Wenzhouxiangella sp. AB-CW3: IC757_04750
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Entry
IC757_04750 CDS
T08427
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
wez
Wenzhouxiangella sp. AB-CW3
Pathway
wez00260
Glycine, serine and threonine metabolism
wez00261
Monobactam biosynthesis
wez00270
Cysteine and methionine metabolism
wez00300
Lysine biosynthesis
wez01100
Metabolic pathways
wez01110
Biosynthesis of secondary metabolites
wez01120
Microbial metabolism in diverse environments
wez01230
Biosynthesis of amino acids
Module
wez_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
wez_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
wez_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
wez00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
IC757_04750 (thrA)
00270 Cysteine and methionine metabolism
IC757_04750 (thrA)
00300 Lysine biosynthesis
IC757_04750 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
IC757_04750 (thrA)
Enzymes [BR:
wez01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
IC757_04750 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
IC757_04750 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
ACT_7
NAD_binding_3
ACT
ACT_AHAS_ss
Motif
Other DBs
NCBI-ProteinID:
QOC23455
UniProt:
A0A7H4GPZ3
LinkDB
All DBs
Position
complement(1093006..1095468)
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AA seq
820 aa
AA seq
DB search
MQWFTHKFGGTSLADADCFRHVAGLLIERDDPAQAVVVSAMAGVTNELVGLTGQAAAGES
GWHERIDALRARHLDTASALLDQPDELESTRAHINQTFDELNQLLLSLALMGTAPIEAIE
LISGLGEVLSARLLSAHLRQLGEDAVFVDAREVLRTRPTAMMTAVDWTESSERLARLRRE
QPSSRYVMTGFICRRADGRISTLGRNGSDYSGTIFGRLFDADEIHIWTNVDGLLSADPDQ
VPQAQLLDHLSYREAFELAYFGARVIHPQALSPALEANIPVLVRNTFKPDCAGTRIDSDG
HPQPPVKGISGISDMALVTIEGAGMIGVPGTAERVFSALNRASVSVTMISQGSSEHSICL
VVPQNDAERACRLLEETFEREMRHGLIQRIFSSSGIRVLAIVGEGMAGTPGVAARLFSSL
ARAGINVRAIAQGASERNISVAVDEVDAERALKAIHAGFYLSEQTLSIGLIGPGQVGGVL
LEQLEQARQRLFEQGRLDIRLSAIAASRRMRLSGADGHLTDHRPLNDDDLTADLDQLTDH
IDDGHMPHALIIDCTASDRVSDRYADWLKRGIHVITPNKHAGSGPLERYVSIRDQVSRGG
ARWRYEATVGAGLPVIQTLRDLLDTGDRILRIEGIFSGTLAWLFNRFEPGMSFAALVAEA
REAGYTEPDPRDDLSGTDVARKLVILAREMGLEIGLDDIEVESLCPDHLTRLDVERFMAT
LPEQDEIMADRVEKASASGQVLRYIASLDESGRASVHLAELPDDHAFANLALTDNVVAFT
TERYRDNPLIIQGPGAGPEVTAAGVFADLLRVAAHLGARL
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcaatggttcactcataaattcggtggcaccagcctggctgatgccgactgtttccgt
catgtcgcgggcctgctgatcgaacgcgacgacccggcccaggccgtggtggtttcggcc
atggccggtgtcaccaacgaactggtgggcctcaccggccaggctgcggccggggagtcc
ggatggcacgagcgtatcgatgcgctgcgcgcacggcatctcgatacggcaagcgcattg
cttgatcaacccgatgaactggaatccacccgggcgcacatcaaccagacctttgatgaa
ctgaaccagttgctgctcagcctggcactgatgggcacggcgccgatcgaggccatcgag
ctgatttccggcctcggcgaagtgctgtcggcacgcttgctttcggcccatctgcgccag
ctcggcgaggacgcggtgtttgtcgatgcgcgcgaggtattgcgcacccgcccgacggcc
atgatgacggctgtcgactggacggaaagcagcgagcgtcttgctcgcctgagacgcgag
cagccatcaagccgctacgtcatgaccggtttcatctgtcgtcgggccgacggtcgtatc
tccacgctgggccgaaacggttctgactattccggaaccatcttcgggcgtctgttcgac
gccgacgagattcatatctggaccaatgtcgatggcctgctgtcggccgaccccgaccag
gtgccgcaggcgcaactgctggatcacctctcctaccgcgaagccttcgagctggcctac
ttcggtgcccgggtcattcacccccaggcgctgagcccggcgctggaggccaatatcccg
gtgctggttcgcaacaccttcaagcccgactgcgcagggacccgcatcgactccgacggc
cacccgcaaccaccggtcaagggcatttccggcatcagcgacatggccctggtcaccatc
gagggggcgggcatgatcggtgtgccgggcacagccgaacgggtgttttccgcactcaac
cgcgccagcgtgtcggtcaccatgatctcgcagggatcctccgagcattcgatctgcctg
gtcgtgcctcagaatgatgccgagcgcgcctgccgcctgctcgaagagaccttcgagcgc
gagatgcgccatggactcatccagcgcattttcagttcatcgggcattcgtgtactggcc
atcgtcggcgagggcatggccggcacacccggcgtggcggcacggctgttctcgtcgctg
gcgcgggccggcatcaatgtgcgcgccatcgcccagggggcttcggagcgcaatatttcc
gtggccgtcgacgaggtcgatgccgaacgtgcgctcaaggccattcacgccggcttctat
ctgtcggagcaaacgctttcgattggactgatcggccccggccaggtgggcggagtcctg
ctggagcagcttgagcaggcccgccagcggctgttcgagcagggccggctcgacattcgc
ctcagcgccattgccgcctcgcgccgcatgcggctgtcgggtgccgatggccacctcacc
gatcatcgcccgctcaacgatgacgatctgaccgccgatctcgatcagctcaccgatcat
atcgatgatggccacatgccgcacgcactgatcatcgactgcaccgccagcgatcgagtt
tccgaccgctacgccgactggctgaagcgcggcattcacgtcatcacgcccaacaagcat
gcgggcagcggtccgctggaacgctacgtttcaatacgagaccaggtcagccgtggcggt
gcacgctggcgctacgaagccaccgtcggcgccggactgcccgtgattcagacgctgcgc
gacctgctcgataccggcgaccgcatactgcgcatcgaaggcattttttccggcaccctg
gcctggctgttcaatcgcttcgagccgggcatgtcatttgccgcactggtggccgaagcg
cgcgaggccggctacaccgaacccgacccccgcgacgacttgtccggcaccgatgtggcc
cgcaagctggtgattctcgctcgcgaaatgggactggagatcggccttgacgacatcgag
gtcgagagcctgtgccccgatcacctgacgcggctggatgtggagcgcttcatggccacc
ctgcccgagcaggacgagatcatggccgatcgtgtcgagaaggccagcgccagcggacag
gtgctgcgctacattgcctcgctcgatgagtccggccgcgcttcagtgcacctggccgaa
ctgcccgacgatcatgcctttgccaacctggccctgaccgacaacgtggtggccttcacc
accgaacgctaccgcgacaatccgctgatcatccagggcccgggcgccgggccagaagtc
accgccgccggcgtgttcgcggatctgctaagggtggcagcccacctcggggcacgattg
tga
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