Williamsia herbipolensis: OG579_08840
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Entry
OG579_08840 CDS
T09708
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
whr
Williamsia herbipolensis
Pathway
whr00860
Porphyrin metabolism
whr01100
Metabolic pathways
whr01110
Biosynthesis of secondary metabolites
whr01120
Microbial metabolism in diverse environments
whr01240
Biosynthesis of cofactors
Module
whr_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
whr_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
whr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
OG579_08840
Enzymes [BR:
whr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
OG579_08840
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
OG579_08840
BRITE hierarchy
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
WUM21853
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All DBs
Position
complement(1974972..1976627)
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AA seq
551 aa
AA seq
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MSRTKKASPGRILFVGSGPGDPALLTLRARDAIASASTVFVDADVPAGVTALIGADIPVE
EPVVRRPEPSSADATADGDDAPVDTPPAVDDQDAAGARIRPALGDPGEVAKTLLAAAKAG
DDVVRLVSGDPLTTDSVLAEVTAVARTSVGFEVIPGLPAAAAVPSYAGMPLGSSHTEADV
RGEVDWAALAAAPGPLVLHATAGHLAETASALTEHGVAAQTPVAVTVNGTTCQQRTIEAT
LATLNDKGAGLQGPLIVTIGKVVAQRGKLSWWESRALYGWTVLVPRTKDQAGDMSDRLVV
HGAIPMEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFAEFGLDAR
AFSGVKIACVGEATAEKVRTFGINPELIPSGEQSSLGLLDDFPPYDDVFDPVNRILLPRA
DIATETLSEGLRDRGWEIDDVTAYRTVRAAPPPATTREMIKTGGFDAVCFTSSSTVRNLV
GIAGKPHARTIVACIGPKTAETATEFGLRVDVQPESASVPDLVDALAEHASRLRAEGALP
PPRKKARRSRS
NT seq
1656 nt
NT seq
+upstream
nt +downstream
nt
atgagccgtacgaagaaggccagtccgggtcggatcctgtttgtcggatcgggccccgga
gatccggcactgctgacgcttcgcgcccgagacgccatcgcctcggcgagcaccgtgttc
gtcgacgccgacgtccccgcgggtgtcaccgctctcatcggggccgacatcccggtcgag
gagcccgtcgtccgccggcccgaaccctcgtcggccgacgcgaccgccgacggtgacgac
gcccccgtcgacaccccgcccgccgtggacgatcaggacgccgcgggcgcacgcatccga
ccggccctgggcgatccgggtgaggtcgccaagaccctgctcgccgccgcgaaggccggc
gacgacgtggtccggctggtctccggcgatccattgaccaccgattccgttctcgccgag
gtcaccgccgtcgcccgcacctcggtcggcttcgaggtcatccccggtctcccggccgcc
gccgcggtgccgagctacgcgggtatgccgctgggctcgtcgcacaccgaggccgacgtc
cgcggcgaggtcgactgggccgcgctcgcggccgcccccggcccgctggtgctccacgcc
accgcaggtcacctggccgagacggccagcgccctcaccgagcacggtgtggcggcgcag
acgccggtcgcggtcaccgtcaacggcaccacctgccagcagcgcaccatcgaggcgacg
ctggcgacgctcaacgacaagggtgcgggtctgcagggaccgctcatcgtcaccatcggc
aaggtcgtcgcccagcgcggcaagctgagctggtgggagtcgcgtgccctgtacggctgg
accgttctggtgccgcgcaccaaggatcaggccggcgacatgagcgatcggctcgtggtg
cacggtgcgatccccatggaggtgccgaccatcgccgtcgagccgccgcgcagtcccgcg
cagatggaacgtgcggtcaagggtctcgtcgacggccgctaccagtgggtggtgttcacc
tccaccaacgcggtgcgtgcggtgtgggagaagttcgccgaattcggtttggacgcacgc
gcgttcagcggcgtcaagatcgcctgcgtcggcgaggccaccgccgagaaggtgcgtacc
ttcggcatcaaccccgaactcatcccgagtggcgagcagtcgtcgctgggtctgctcgac
gacttcccgccctacgacgacgtgttcgacccggtgaaccggatcctgttgccgcgcgcc
gacatcgcgaccgagacgctctcggagggtctgcgtgatcgtggctgggagatcgacgac
gtcaccgcctaccgcaccgtgcgggcggcgccgccgccggcgaccacccgcgagatgatc
aagaccggcgggttcgacgcggtctgcttcacctcgagctccaccgtccgcaacctcgtc
ggcatcgcgggcaagccgcatgcgcgcaccatcgtggcgtgcatcggacccaagaccgcc
gagacggcaacggaattcggcctgcgggtcgatgtccagcccgagtcggcgtcggtgccc
gatctcgtcgacgccctcgccgagcacgcctcgcgtctgcgcgccgaaggtgctctgccc
ccgccgcgcaagaaggcccggcgctcccggtcctga
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