Williamsia herbipolensis: OG579_13570
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Entry
OG579_13570 CDS
T09708
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
whr
Williamsia herbipolensis
Pathway
whr00300
Lysine biosynthesis
whr00550
Peptidoglycan biosynthesis
whr01100
Metabolic pathways
whr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
whr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
OG579_13570
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
OG579_13570
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
OG579_13570
Enzymes [BR:
whr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
OG579_13570
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CbiC
Motif
Other DBs
NCBI-ProteinID:
WUM18763
UniProt:
A0AAU4JY93
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All DBs
Position
2992619..2993950
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AA seq
443 aa
AA seq
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MQFTATEVAAATGGRLIGPDTTVSGAGIDSRTITAGQLFVPIVAARDGHEFIGTAVAAGA
SVTLASTPVDVPGVTVVEVDDTATALARLGTAARDRVTGPVIGVTGSVGKTSTKDLLARV
LSTGLRTAANERSFNNELGLPLTLFNAPDDTEAVVVEMGARGVGHIATLCEIAHPTIGVV
TRVDGVHLELFGDIASIVQAKGELIASLPDDGLAVLNADQAEVVSMAARTSARVIAYGSA
PTADVRATDIRVDAELRPTFVLHTPWGSIEVSMQARGRHQVHNALAAAAVAGGIGLGVDR
IAEGLSGAAISGLRMELSRTDSGVQILNDSYNANPTSMVAALEALAGLTGNRKLAVLGVM
AELGGTARAEHLAISDRAAELGIDVIAVDAPDYGPRATHVADIDDAVLALGDLGDGDAVL
VKGSRVAALERVAQALLTTTGAH
NT seq
1332 nt
NT seq
+upstream
nt +downstream
nt
gtgcaattcacagcaacggaggtggccgcggcgaccggtggtcgcctgatcggccccgac
acgacggtgtcgggcgcaggcatcgactcgcgcaccatcaccgccggtcagctgttcgtg
cccatcgtggccgcacgagacggccacgagttcatcggcaccgcggtggccgcgggtgcg
agcgtgaccctggcctcgaccccggtcgacgtcccgggggtgaccgtcgtcgaggtcgac
gacaccgcgacggcgctcgcccgcctcggcacggcggcccgtgaccgtgtcaccggccct
gtcatcggcgtcaccgggtcggtcggcaagacctcgacgaaggacctcctggcgcgcgtc
ctgtcgacgggtctgcggaccgcggccaacgagcgctcgttcaacaacgagctcggcctg
ccgctgaccctgttcaacgcccccgatgacaccgaggccgtcgtggtggagatgggtgcg
cgcggcgtcggccacatcgcgacactctgcgagatcgcccatccgacgatcggggtcgtg
acccgggtcgacggcgtgcatctcgaactgttcggcgacatcgcctcgatcgtgcaggcc
aagggcgagctcatcgcgtcgctccccgacgacggtctcgccgtgctcaacgccgatcag
gcggaggtggtgtcgatggcggcacgcacctcggcgcgggtcatcgcctacgggtcggcg
cccaccgccgatgtccgcgccaccgacatccgtgtcgacgccgaactccgacccaccttc
gtgctgcacaccccgtgggggtcgatcgaggtgtcgatgcaggcgcgcggccgtcaccag
gtccacaacgcgctcgccgcggcggcggtcgccggcgggatcgggctcggtgtcgatcgc
atcgccgagggcctgtcgggtgcggcgatctccggtctgcgcatggaactgtcgcgcacc
gactccggtgtgcagatcctcaacgactcctacaacgccaacccgacgtcgatggtcgcc
gcactggaggcgctcgccgggctgacgggcaaccgcaagctcgccgtcctgggtgtcatg
gccgagctcggcggcaccgcgcgcgccgagcacctcgcgatcagtgaccgcgccgccgaa
ctggggatcgacgtgatcgccgtcgacgcgccggattacggtccgcgcgccacccatgtc
gccgacatcgacgacgccgtgctggccctcggcgatctcggggacggggacgcggtcctg
gtgaagggcagtcgggtcgccgcgctcgaacgggtggcgcaggccctgctcacgaccacg
ggcgcgcactga
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