Xanthomonas sp. SI: HEP75_03487
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Entry
HEP75_03487 CDS
T10656
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
xai Xanthomonas sp. SI
Pathway
xai00300
Lysine biosynthesis
xai00550
Peptidoglycan biosynthesis
xai01100
Metabolic pathways
xai01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
xai00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HEP75_03487
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HEP75_03487
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HEP75_03487
Enzymes [BR:
xai01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HEP75_03487
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Paralog
Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QNH14019
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Position
complement(4186803..4188335)
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AA seq
510 aa
AA seq
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MKRLPLSMIAHWAGAELHGDDVAIDAIAHDTRTLAPGSLYVALRGERFDGHDFVADAAAR
GASALLVELLQPQIELPQILVADTQLALARIAAGMQRGRATRVAAITGSNGKTSVKALLL
AILQHACRVNGGSVYANPGNRNNEIGLPLAVIEAPDAADYAIYEMGAGKPGDIAYLTDIV
APHAALVNNIAPAHLERMGSLLGVAETKGAIYAALSADGTAVINADDAFGLWFEQRLPAP
LAPRVLRFGLQASAEVSATQLRMRADRSQFVLVTPQGEIETTLPLPGRHNLMNALAAASL
ALALDIAPALIAAGLAQVQPVPGRQIAHTLPGGAVLIDDSYNANPGSLAAAIDALAAAGG
ERWLVLGDMRELGDGAEALHASGGRRARDAGLTRLYALGPLSAVAAQAFGENGRVFDSHA
ALIAALRADLRAAGTRDSGLGTRQQQDQDQEPKQMHENTGAAADGVAPLRVPSPESRVPA
TLLVKGSRGSAMDKIVSALLAQGEEAPHAA
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgcctgccgctgtcgatgatcgcgcactgggccggcgccgagctgcacggcgac
gatgtggcgatcgatgcgatcgcccacgacacccgcacgctggcgccgggcagcctgtac
gtggcgctgcgcggcgagcgtttcgacggtcacgacttcgtcgccgatgccgccgcgcgc
ggcgccagcgcattgctggtggaactgctgcagccgcaaatcgaattgccgcagatcctg
gtcgccgacacccagttggcattggcgcggatcgccgccggcatgcagcgcggccgcgcc
acgcgggtggccgcgatcaccggcagcaacggcaagaccagcgtcaaggcgctgctgctg
gcgatcctgcagcatgcctgccgtgtgaacggcggcagcgtctacgccaatcccggcaac
cgcaacaacgagatcggcctgccgctggcggtgatcgaagcgccggacgcggccgactac
gcgatctacgagatgggcgcgggcaagccgggcgatatcgcctacctgaccgacatcgtc
gccccgcatgcggcgctggtgaacaacatcgccccggcgcatctggagcggatgggcagc
ctgctcggcgtcgccgagaccaagggtgcgatctacgccgcactgagcgccgacggcacc
gcggtgatcaatgccgacgacgcgttcgggctgtggttcgaacagcgcctgccggcgccg
ctggccccgcgcgtgctgcgcttcggcctgcaggccagcgccgaggtcagcgccacgcag
ctgcgcatgcgcgcggaccgctcgcagttcgtgctggtcaccccacagggcgagatcgag
accacgctgccgttgccgggccggcacaacctgatgaacgcactggccgccgcctcgctg
gcgctggcgctggacatcgcgccggcgctgatcgccgcgggcctggcgcaggtgcagccg
gtgccgggccgacagatcgcgcacacgctgcccggcggcgcggtgctgatcgacgacagc
tacaacgccaatcccggttcgctggccgcggcgatcgacgcactggccgcggccggcggc
gagcgctggctggtgctgggcgacatgcgcgaactcggcgacggcgccgaggcgctgcac
gccagcggcggccgccgcgcccgcgatgccggcctgacccggctgtacgcgctgggtccg
ctcagcgccgtcgccgcgcaggcgttcggcgagaacggccgcgtgttcgacagccatgcg
gcgttgatcgccgcgctgcgtgcggaccttcgtgcggccgggactcgggactcgggactc
gggactcggcaacagcaggatcaagatcaggaaccaaagcaaatgcatgagaacactggc
gcggcggcagatggcgttgcgcctttacgagtcccgagtcccgagtcccgagtcccggcc
acgcttctggtcaaaggttcccgcggcagcgccatggacaagatcgtgagcgcgctgctg
gcgcagggagaggaggcgccgcatgctgcttga
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