Xanthomonas sp. SS: HEP74_03413
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Entry
HEP74_03413 CDS
T09534
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
xas
Xanthomonas sp. SS
Pathway
xas00300
Lysine biosynthesis
xas00550
Peptidoglycan biosynthesis
xas01100
Metabolic pathways
xas01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
xas00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HEP74_03413
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HEP74_03413
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HEP74_03413
Enzymes [BR:
xas01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HEP74_03413
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QNH18241
LinkDB
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Position
complement(4115532..4117049)
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AA seq
505 aa
AA seq
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MKRLPLSMIAHWAGAELHGDDVAIDAIAHDTRTLAPGSLYVALRGERFDGHDFVADAAAR
GASALLVELLQPQIELPQILVADTQLALARIAAGMQRGRATRVAAITGSNGKTSVKALLL
AILQHACRVNGGSVYANPGNRNNEIGLPLAVIEAPDAADYAIYEMGAGKPGDIAYLTDIV
APDAALVNNIAPAHLERMGSLLGVAETKGAIYAALTADGTAVINADDAFGLWFEQRLPAP
LAPRVLRFGLQASAEVTATQLRMRADRSQFVLVTPQGEIETTLPLPGRHNLMNALAAASL
ALALDIAPALIAAGLAQVQPVPGRQIAHTLPGGAVLIDDSYNANPGSLAAAIDALAAAGG
ERWLVLGDMRELGDGAEALHASGGRRARDAGLTRLYALGPLSAVAAQAFGENGRVFDSHA
ALIAALRADLRAATVGPREEQDQEQETEQMHESTGAASAGVAPLRIPSPESRVPATLLVK
GSRGSAMDKIVSALLAQGEEAPHAA
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgcctgccgctgtcgatgatcgcgcactgggccggcgccgagctgcacggcgat
gacgtggcgatcgatgcgatcgcccacgacacccgcacgctggcgccgggcagtctgtac
gtggcgctgcgcggcgaacgtttcgacggtcacgacttcgtcgccgatgccgccgcgcgc
ggcgccagcgcattgctggtggaactgctgcagccgcaaatcgaattgccgcagatcctg
gttgccgacacccagttggcattggcgcggatcgccgccggcatgcagcgcggccgcgcc
acgcgggtggccgcgatcaccggcagcaacggcaagaccagcgtcaaggcgctactgctg
gcgatcctgcagcatgcttgccgggtgaacggcggcagcgtctacgccaatcccggcaac
cgcaacaacgagatcggcctgccgttggcggtgatcgaagcgccggacgcggccgactac
gcgatctacgagatgggcgccggcaagccgggcgacatcgcctacctgaccgacatcgtc
gcccccgatgcggcgctggtgaacaacatcgccccggcgcatctggagcggatgggcagc
ctgctcggcgtcgccgagaccaagggtgcgatctacgccgcactgaccgccgacggtacc
gcggtgatcaatgccgacgacgcgttcgggctgtggttcgaacagcgcctgccggcgccg
ctggctccgcgcgtgctgcgcttcggcctgcaggccagcgccgaggtcaccgccacgcag
ctgcgcatgcgcgcggaccgctcgcagttcgtgctggtcaccccgcagggcgagatcgaa
accacgctgccgctgccgggtcggcacaacctgatgaacgcactggccgccgcctcgctg
gcgctggcgctggacatcgcgccggcgctgatcgccgcgggcctggcgcaggtgcagccg
gtgccgggccgacagatcgcgcacacgctgcccggcggcgcggtgctgatcgacgacagc
tacaacgccaaccccgggtcgctggccgcggcgatcgacgcgctggccgcggccggtggc
gagcgctggctggtgctgggcgacatgcgcgaactcggcgacggcgccgaggcgctgcac
gccagcggcggccgccgcgcccgcgacgctggcctgacccggctgtacgcgctgggcccg
ctcagcgccgtcgccgcgcaggccttcggcgagaacggccgcgtgttcgacagccacgcg
gcgttgatcgccgcgttgcgcgcggatctgcgtgcggccacggtcgggcctcgggaagag
caggatcaagagcaggaaacagaacaaatgcatgagagcaccggtgcggcgtccgctggc
gttgcgcccctccgaatcccgagtcccgagtcccgagtcccggccacgctcctggtcaaa
ggttcgcgcggcagcgccatggacaagatcgtgagcgcgctgctggcgcagggagaggag
gcgccgcatgctgcttga
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