Xenorhabdus bovienii SS-2004: XBJ1_1089 Help Entry XBJ1_1089         CDS       T01186                                  Name (GenBank) putative toxin RtxA protein   KO K10953   RTX toxin RtxA Organism xbo  Xenorhabdus bovienii SS-2004 Brite KEGG Orthology (KO) [BR:xbo00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    02042 Bacterial toxins [BR:xbo02042]     XBJ1_1089 Bacterial toxins [BR:xbo02042]  Type II toxins: Membrane damaging toxins   Pore-forming toxins, RTX    XBJ1_1089 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RtxA Peptidase_C80 MLD RtxA_C Hydrolase_4 Abhydrolase_1 Abhydrolase_6 Abhydrolase_3 Thioesterase Abhydrolase_11 DUF818 Motif Other DBs NCBI-ProteinID:  CBJ80230 UniProt:  D3UXB8 LinkDB All DBs Position complement(1084951..1099101) Genome browser AA seq 4716 aa AA seqDB search MGKSSNRSAAYAFTGKYEDDNDGNTIHAIGIGGVINAYGGNDYIVVGSVGATVNTTWGND TVVGAAGYLNINDTSGTLTVKGGSGYTSINKTSDGTIDFAGAAGGLKINHTGDKGRIDYS GASGYNGITRKGWEGDFTFKGAGGYNELWHETNQGNFYFAGVGGGNKIDRTWFDRYQGSH GDLTFNGAGAANIISSRVESGDIVFAGAGAANNLVRRGKTGNVTLTGAGASNRIERTRQT DDVYSETKGDIKFEGAGGYNSLYSDVAHGNIRFAGVGGYNHITRKGTATDFDNEGMEYAK AEDIVLKNATMSGDWIGYNVQVTGLKSARESNTYLFAFADGMYTKINKVQLRNDPETGKL IYHSTSWYKEGNHLKTLDKQDISVQGGFKDVKIDGAYTLSNLTVEHQQSVTVHAVEEKLA EDQWMNHGDGVLVDVADVTLSNAKMGGYAIDSKGSTADVQVVKSNHKSNTYIYAKRIDKY TKIVVIELRNDPKTGMLQYNAQAWFSLEDRMAKLANEDISSANGYQAVPAGIYTLSDLHY STKAVRTASGRVSGMHEYRDLALFKSATGSGESSGDVRYTGAGGGNVIQSNVTRGNVYFD GAGIANVIEHTSEFGNTEFNGGGAANVIVKKGKEGNLTFNGVGIANVLLHQGLRGDMDVN AGGAANILVRVGDGRYLAHLLAVGNISIHKGNGNSRISMSGGFNTHTQIGHGDAFWSGVG GFNVLTQMGKGHVSSILLGGANVLSKVGEGDLESGMLGGANIITHISNDRETSNTKAIAL GGANILTKKGKGDVLSVMGGGANVLTHVGDGKTTGILLGGANILTKVGNGDTTGIMLGLG NILTHVGNGQTLGVMAAAGNIFTKVGEGTTIAAMVGAGNIFTHVGQGNAWALMGGIGNIF TKVGDGDALALMLAAGNVFTHVGDGMSVALMVAKGNIATKVGHGEMLSAMIGEGNILTQI GNGDTFAAMLGKANILTKVGNGLTAALMVSEANIYTHVGDGTSIGLFVGSVNVMTKVGNG TTLAAMFGKANIMTHVGDGLTGVLALGKANIMTKVGNDFMGVVAASEANVVTHVGGGTTA ALLLGKGNVLTKVGDGTTVGLLVSKIGNVMTHLGDGTTIGFAKGEANIITKSGDGLGINA AWGKANIMTHIGEGDRYNFAKGEANIITKVGDGQEITVVQGQANIVTHVGNGDDYTGAWG KANVITKVGDGRNVVLAKGDANIVTQIGNGDSFNALWSQGNVVTKVGDGMQVTAAKGKGN ITTTVGNGLSVTTVHGDLNVNTKVGDGVSVNVAWGKLNVNTRVGDGLNVSVMKGQANANI RVGDGLNINASYARNNVAIQVGNGDFYSLAVAESNTESNKLSALFGNVKQTLLGVAGSQG ISHLVNGDEANTSGTHKGRGAIDLPEVSALNGFQLTEVKQVTSDLQQSLKGSVTGVDTPD IGSIQNTLGNEKRLKSNQSRNLIVNGDFEQGADGWQATNGIEASYAAQAYGLSNEGHGER VSELDADTHADKDSNTSIYQDISDLTANESITLSFDFAKRAGISADNGMEVLWNGKTVFS ISAGNAEWQNKTLSLTAQTGSNRLEFKGTGTNDGLGYILDNVVAKSEQPDSAIADHVQQD AAAQNALQDKEKAEADRQRLEQERDTQLAAVSGSQAQLEATDLEALNRNGQDQRDAINHE AQAITKELTEQAKGLSALDSHSKHHGKSGEQWRAQFAEGLLGQVQTQLNSADETAQQQLD RSQHAASERFGDLRDAVAKSEAGVSKGEQNQQQSQKEIEQTRTNAEFRKQQALSQKTQAE HAESNAKAAVQKAGQRGQHEVSEADSQTARVQSDAKAAKQSDNYKPNRTGAAGSGLSGSA YESNAAENQPERVKTDNPIGFAPKNETNTGFSKELQYLDEDLDELAEAKEALNRLQINAT KRGKNTGATLISAYTETSVGQPVSKTADVSTEWVRNTPKISGLDLSGLQALGETHVQQGS ADAPEMSATAIRAQKVADVYRWLDSDNNIATDTYIPVPGFERGDADIPENIRQKLVTFIE GYLEGTDNSVPKDQVAPLAKLFVDATIDCNWDKRVEFVSKLEQYGYSFEPVHGDKSIVSF WSGKNFKQYRSVLDAVQTDGKKVVYDIDVKGNSFAIELNKTLMRWGNVYLDSDNAEHNAL QTAINTSARSNTGFWSSLYATGSRDDVYVIAEGGLRLGNYFWNVELPVLRQLQREGLVGE IRLLDKPAREYQGAAPESIGRRLTEAGVSVKARFDSLSIGEQERLLTLNPTGYKPDTLID LDIKLSAIDNMLNQALPFYGLRTERNLLVREADDEGFEVRRWPGHDGDDFKTIIVEDAGD PAQIRAIERFILANYDDYGKLPDALYLVADQIVSHEQGRTRIVAKKADGSWNYKPKTDLM SASEFKDAAYVKGKILGDSYRNVLEAFGSYEKALQNGADYDLDVVEKLISLHQQVEGYLL GHPDSKRLPAMTNLLSQINVRMEESRVLAEPTLTSVGKGNFSELYNKLGNANLKDSKHLY IDEQGDFVTRGKSNIQIAMKAEGAEKAVEQIKAAVTREYGQEVAETVFSNLKSRDLSKDG KGIDVSGLRKVHQAIEQQLSPVSATLFVWKPSDHSQLGHAALQIGQGRFQVSAEDAEGFN EKNYVSWWPKGGKSTSPGHIFNVSTEENPDVSLRWRDLSQPASQNETLAFDVGSEEGDNF GLKDGTYKLEKFIEKLQAAKGVDAKFEDISEGFAMAALANPNLLKSAGIPEHISRPFIEQ WENGNIDMQDIGRDFAEALRTAAKQKVTPELTEKRITNIIRQFAERELSDIQDFKASEAD QGRVFRINLAGLDTAAMQTEWNKISQNPDARYQILNGNCSSIVAKVLKAGGADKVIGHTW RPNFGIWTPTELFNYAQKLQEAQIEIIANKPKRIVGEDLEALGQPDKKDNVLEKVAIDND GKPPRDREPFNPVTRFLNNELYGAKEERRNVYDYTQTALDTAVTNGTADKVTLRGDAGRL TGYYHQGEQKTDASAEPNTAKKVVLFIHGSGSSAEEQASVIKNQYQKQGIDMLAVNLRGY GSSDGRPSEKGLYHDARTMFRYLVNDRGVRPENIIIHGYSMGGPIAADLARYAERNGHTV SGLLLDRPMPSMTKAITAHEVPNPAGMTGVLAKAVNGQFSVEKNLQGSSKQTPIMLLTDN EGLGEAGEKLRAKLVIDGYQVSGEHTFYSHEASSRLMNQYAEQIVTGLFDVKRQPDESTA LKGLRSDLKRYGEALEPQKSAPGKTKDIRATQDFLTGYQQGHAEQTVDGFRSDMNIKQLV DLLVKGNWTAEQKGSLAWEIESRALKVTFQPQAEKHNRLFNDVVSSGVADTKASKHLAPQ LLLLNLSNDGFGGRCDPLSKLVLVAKQLENNGQDGVARKLLEKMYSAAAVLSNPTLYSDT ERGNANKLLGSLAALHARNPMHDTSIKVWQEKLEDKQALTVNGVIGKVTAANADGKPVLL ELDAPGHAMAAWAKGSGDNRVYGFYDPNAGIVEFSSAEKFGDYLTRFFGKSGLNMEQSYK LPKNAAGEIIFKRVVVMDGSVLATYNPTRADKTTMQGILDLNIFDETPIKTHSDVEITHE VKVPLKDNLPEGVDRVVNNENVEHWEPAFVKPQAEGGDSRFNSQVIIQTENDPVAAKAAA RLAGKHPDSSVIVQLDANGRYRVVYGDPATLSGKLRWQIVGHGRDESVQHHTRMSGYSAD ELALKLKQFRTDFKQAGSPDHISLVGCSLISDDKRDGFARHFISELDKQGIRTTVSARSS EVAVDSIGRKFTRNAEEQWVHKLMDNKIVLGWNDKGELETHAERIRRGISENDINLSRIG HIDTDAKAKGAIAENAETFHAPEQHKKVNDDASATSSAKSSNNKLSYSGNIQVQAGDGEF TVINWGTTNVGIKVGTGGFKSLAFGDNNVMVHLGNGDSKHSVNIAGYQALEGAQLFMGNR NVSFNMGRSNDLIVMMDKSIPTPPLVNPFDGASRISGVLQNIAGSFESPDWLTAQDQQWT LESAKKYVSDLSGLDLTSSVDYNTLTDLDTENEKSSRGLKSDIETTLNKKYNQWLGRNGN AREMGNVSRADKFRQENETLAFNFAVGGQGADIQVTTGNWNFMFGDNIQSILDTNLGSLF GLMTQEYTSTGMAKTTFTFSPKDLPRQLKNKLLGNLAGVSADTTLADIFGVDYTADGHIV SRSGQSVDGVAILREMLEVIGEFSGNQLQAFTDPAKLLDSLEAGLNTGADGVKSFAESHG LQAKAPEENKEGHVSISTEGKPVQEVAELPSDRALGFNLPSLFTTLFKQNKQVEMASLVA DLKQNLTADLLNIQDKTFDFLRNSGHLQGDGDMHVSLGNYNFNWGGDGKDLGAYLGDNNN FWGGRGDDVYYSVGTSNIFTGGEGNDMGVLMGRENMMFGGAGNDVAVLAGRINYAYMGDG DDQVFVFGEGGVIEGGKGRDYIVASGNFNSIHAGEGQDYVVAIGNNNQVSLGEGDDFATV FGNYNNIDGNAGNNAIKLMGYHAVINGGTGDDHLIANVASKFSQLNGGDGDDLLVLGGYQ NNFKGGTGVNSFVVSGDVIDNVVEDIKRGDKIIFNNLNWQKLWFQRSGYDLVLLTGRDVT DTSAQGKFEAIGSVTFNDYFNGNRADIVTQMGDKDTQGEREYTALSANSVDSLVQAMSGF APNMGDTGFIDTLDSQTKSTIVTAWADTTSGKSKLA NT seq 14151 nt NT seq  +upstreamnt  +downstreamnt atgggaaaatcatccaaccgaagtgcagcatatgcctttaccggtaaatatgaagatgat aatgatggaaatacaatacacgccatcggcattggcggtgtcattaacgcctatggcgga aatgattacattgtcgtgggttccgttggtgcaaccgtcaatacaacatgggggaacgat actgtcgtgggggcggccgggtatctgaatattaacgatacaagcggtactctgacggta aaaggaggttcaggttatacctccatcaataaaacaagcgatggcacgatagattttgct ggcgctgccggtggactgaaaatcaatcacacaggtgataagggtcgaatcgattattct ggcgcgtctggctacaatggcatcacccgcaagggatgggaaggcgatttcacttttaag ggcgcaggggggtataacgaactctggcatgaaaccaatcagggaaatttctactttgct ggcgtggggggtggaaacaagattgatcgcacatggttcgaccgttatcagggatctcac ggcgatctgacctttaacggcgctggtgcggcaaacatcatcagttccagagttgaaagt ggtgatattgtttttgcaggcgcaggagccgctaacaatcttgtccgcaggggaaaaacc ggcaacgtcaccttaacgggtgcaggggcttctaaccgtattgaacgtacccgccagacc gatgacgtctattctgaaaccaaaggtgatatcaagtttgaaggcgcgggcggttataac agcctgtattctgatgttgcacacggtaatatccgttttgcaggagtgggggggtataac catattacccgcaagggaacggccactgacttcgataacgaaggcatggaatatgccaaa gccgaagatatcgtgttgaaaaatgccaccatgagtggtgactggattggctacaacgtg caggtgacaggtcttaaatcggcacgggaatcgaacacttatctgtttgcgtttgctgat ggcatgtataccaaaatcaacaaagttcagctccgcaatgatcctgaaaccggcaaactg atctatcactcgacgtcttggtataaggaaggaaaccatctcaagacgttagataaacag gatatctctgttcagggtggttttaaggatgtcaagattgacggtgcttacaccctgtca aacttgacggttgaacaccagcaatctgttaccgttcacgctgttgaggaaaaactggct gaagaccaatggatgaatcatggcgatggcgtgctggttgatgtggcagatgtcacatta tcaaatgccaaaatgggtggctatgcgattgacagtaaaggaagcaccgctgatgtacaa gtggtgaaatccaaccataaatcgaacacttatatctatgccaagcgaatcgataaatac accaaaatcgtggttattgaactgaggaacgatccaaaaacaggcatgctgcaatataac gcacaggcttggttcagtttggaagatcgcatggcgaaactggcgaacgaagatatttct tctgctaatggttatcaggccgtgccagcgggtatctatactctgagtgatcttcattac agtaccaaggcagtacgtacagcttcagggcgcgtatctggcatgcacgaataccgtgat ctggcgttattcaaatcggcgaccggcagcggtgaaagctccggtgatgtccggtataca ggcgcgggtggcggcaacgttatccaatcgaacgtaacccgaggcaatgtctattttgat ggagccggtattgccaatgttattgaacatacttctgagtttggtaacacggaatttaat ggcggcggagcggcgaacgtcatcgtcaaaaaaggcaaagaaggcaacctgaccttcaac ggtgtcggcattgccaacgtactgctgcatcaaggcttgcgtggcgacatggacgtgaat gcgggtggtgcggctaatatactggttcgcgtcggtgatggccgctatcttgcccatctt ttggcggtcggcaatatctccattcacaagggcaacggcaacagccgtatctcaatgagc ggtggtttcaatacccacacacaaatcggtcatggcgacgcattctggtctggtgtcggt ggcttcaatgtcttgactcaaatggggaaagggcatgtttcctcaattctgctgggcggc gccaacgttctgagcaaagttggcgaaggcgatcttgaatccggcatgttaggcggcgcc aacatcattacccatatcagcaatgatcgtgagacgtccaacacgaaagccatcgcactg ggtggtgccaatatcctgactaaaaagggcaaaggagacgtattgtcggtcatgggcggg ggtgccaacgttctgacccatgttggggatggcaaaaccaccggtatcctgctgggcggc gcgaacattctgactaaagtcggcaacggcgataccacgggcatcatgttgggtcttggt aacattctgactcatgtcggtaatggacagacgctgggcgtgatggcggcggcgggtaac attttcaccaaagtgggagagggtacaaccatcgcggctatggtgggtgcaggtaacatt ttcactcacgttggtcagggaaatgcctgggcgctgatggggggtattgggaatatcttc accaaagttggcgatggtgacgcactggcattaatgttggctgccggcaatgtgttcacg cacgtgggtgatggtatgagcgtggctttgatggttgccaaaggcaacattgcgactaaa gtcggccatggtgaaatgctttctgccatgattggcgagggcaatatccttactcagatt ggtaacggtgacacctttgccgccatgctgggtaaggcgaacattctgactaaagtcggc aatggtctgacagccgcgttgatggtgagtgaagccaacatttatacccatgtgggtgat ggaaccagcatcggcctgtttgtgggttctgtcaacgtgatgaccaaagtgggcaatgga accacccttgcggctatgtttggcaaagccaatatcatgacgcatgtcggcgacggtttg actggtgtccttgcattgggcaaagccaacatcatgacaaaagtcggcaacgatttcatg ggggttgttgcggcttctgaggctaacgtggtgacccatgttggtggtggcaccacagca gccctgctgcttggcaaaggcaacgtgctgaccaaagtgggcgacggaaccaccgtgggc ttactggtttccaaaatcggcaacgtcatgactcatcttggtgatggaaccaccatcggg ttcgccaagggtgaagccaacatcattaccaagtcgggtgatgggttgggcatcaatgcc gcttggggcaaggccaacatcatgacccatattggtgagggtgatcgctataactttgcc aaaggtgaagcgaatatcatcactaaagtgggtgacggacaggaaattaccgtagtccag gggcaagccaacattgtgactcatgtaggcaatggcgatgattacacgggtgcctggggt aaggctaacgtgatcaccaaagtgggtgacggacgtaatgtcgtacttgccaaaggcgat gccaatatcgtgacccagatcggtaatggggatagtttcaacgcactgtggagtcagggc aatgttgtcaccaaagtcggtgatggcatgcaggtcacggcagccaaaggtaaaggcaac atcacgacgaccgtaggcaatggcctgagtgttaccaccgtccacggtgatctgaatgtc aataccaaagtgggtgatggcgtttccgtcaatgtggcctggggcaaactcaacgtcaat acccgagtgggtgatggcctgaatgtttccgtcatgaaaggtcaggcaaatgccaatatc cgtgtgggtgacggcttaaacattaacgcctcttatgcccgcaataacgtggcgattcag gtgggcaatggcgatttctatagccttgccgttgcagaaagcaataccgagagtaataag ctgagtgccttgtttggcaacgtgaagcagacactgcttggtgtggcaggcagtcagggt atcagccatctggttaatggagacgaagccaacacatcgggaactcataagggacgcggt gcaattgatctgcccgaagtttctgcgctgaatggcttccagttgactgaagtgaagcag gtcacatctgatttgcagcaaagcctgaaaggttcggtgacaggcgttgatactccagac attggcagtatccagaataccttgggcaatgaaaaacggttgaagtctaatcaatcgcgc aatctcattgtcaatggagactttgagcagggcgcagacggctggcaggccaccaatggt attgaagcctcttatgctgcacaggcctatggccttagtaatgagggtcatggcgaacgc gtcagtgaactcgatgctgatacccatgctgataaggattctaataccagtatttatcag gatattagtgatctcactgcgaatgaatccatcacgctgagttttgattttgcaaaacgc gccggtatttctgcggacaacggtatggaagtgttgtggaacggaaaaaccgtgttctcg atttccgcaggtaacgcggaatggcaaaacaaaacattgtcattaaccgcacagacgggc agcaaccggctggagtttaaaggcacaggcacaaatgatggtctgggctacattctggat aatgtcgttgccaaatctgagcagccagacagtgctattgctgaccatgtgcagcaggac gccgccgcacagaatgcgttacaggataaagaaaaagccgaagcggatcgccagcgtctg gaacaggaaagggatacacaactggccgcagtttctggctctcaggcacaattggaagcc acggatctggaggcgctgaataggaatggacaagaccagcgcgatgcaataaatcatgaa gcccaagctattaccaaagaattgacggaacaagctaaagggttgtcagcgctcgatagc cacagtaaacatcatggaaaatccggtgaacagtggcgagcccaatttgcggagggtttg ttaggacaggttcagacacaactgaatagtgcagacgaaacagcacagcagcagttggat cgctcacagcacgcggcttcagaacgtttcggtgatctcagagacgcagtggccaaatca gaagccggagtcagcaaaggcgagcaaaaccagcagcagtctcaaaaagagattgaacag acccgcaccaatgccgaattcaggaagcagcaagccttaagccaaaagacacaggctgaa cacgctgaaagtaacgctaaagccgcagtgcagaaagccggacagcgtggtcaacatgaa gtttctgaggcagacagccagacagcacgggtgcaatcggatgccaaagccgcaaaacag agtgacaactacaaaccgaaccgcacgggtgcagcaggcagtggtctgtcaggctccgcc tatgagtccaatgccgctgaaaaccagcctgagcgggtaaaaacggataatcctatcggt tttgcaccgaaaaatgagacaaataccgggttcagtaaggaattacaatatctggatgaa gacctcgacgagttggctgaggcaaaagaagcattgaatcgcttacagatcaatgcaaca aaacgcggtaaaaataccggggctaccctgatatcggcttatacagaaacgtctgtcggt cagccggtcagcaagaccgcagatgtgtctaccgaatgggtcagaaacacgccgaaaatt tccggtctggatctcagtggcctgcaagcactgggtgaaacccatgttcagcagggatct gccgatgcaccagaaatgtctgctactgccatcagagcgcaaaaagttgcagatgtttac cgttggctggacagtgacaacaacattgctacagatacttatattccggtgcccgggttt gagcgtggggatgctgatattcccgagaacatcagacagaaactggtgacctttattgaa ggataccttgagggaactgacaatagtgtgccgaaagatcaagtcgccccgttggcgaaa ctgttcgttgatgccacgattgattgtaactgggataagcgtgtcgaatttgtctcaaaa ctggaacaatatggctatagttttgagcctgtccatggcgataaaagcatcgtgtcgttc tggtctggcaaaaacttcaagcaataccgcagtgttcttgatgccgtgcagaccgacggc aagaaagtggtttacgatattgatgtgaaaggcaactcttttgccatcgaactgaacaaa accctgatgcgttggggcaacgtatatctcgattctgacaatgccgaacataacgcatta caaacggccattaatacttcggcacggagcaacaccgggttctggagctccctctatgcc accggatcacgcgatgatgtgtatgtgatcgcagaaggtggcctgcgtcttggcaactac ttctggaatgttgaactgccggtattgcgccaattgcagcgtgaagggctggtgggagaa atccgtctgctggataaacctgcccgtgaatatcagggtgcggcaccggaatctattggt cgcaggctgacggaagccggcgtctctgtgaaagcacgttttgattctctcagcattggc gaacaggaaagattgcttacgctgaatccgactgggtataagccggatacactgattgat ctcgacataaaactgagcgccatcgacaacatgttgaatcaggcattgccattctacgga ctgcggacagagcgcaacctgctggtacgtgaagctgatgatgaaggctttgaagtgcgc cggtggccgggtcatgatggtgatgacttcaagacgatcattgtggaagatgcgggagat ccggctcagatcagggccattgagcgtttcatcctcgccaactacgacgattacggaaaa ctgccggatgctttgtatttggtggcagaccagattgtttcccacgagcaggggcgtacc cgtatcgtggctaaaaaagcggatggcagttggaactacaaaccgaagactgacttgatg tctgccagtgagtttaaggatgcggcttacgttaaaggtaaaatcctcggtgacagttac cgcaacgtactggaagcgttcggcagttacgaaaaagccctgcaaaacggcgcagactat gatctggatgtcgtggagaaactcatcagcctgcatcagcaagttgaaggttatctattg gggcatcctgattcaaaacgcttacccgccatgacaaacctgttgtcacaaatcaatgtg cgcatggaagaatcgcgggtactggcggaacctacattgacaagtgtgggtaagggcaat ttcagtgagttgtataacaaactcggcaatgccaacctcaaagattcaaaacatctttat attgatgagcagggtgattttgttacccgtggtaaatctaatattcagatagcgatgaaa gcggaaggagcggaaaaagcggtcgagcagatcaaagccgccgtgaccagagaatatggt caggaagtagcagaaaccgtcttttcaaacctgaaatcccgtgatttgtcaaaagatggc aaaggcattgatgtgtctggcttgagaaaggtgcatcaggcaattgaacagcaactgtct ccggtcagtgccactctgtttgtctggaaaccgagcgatcacagccaactgggacatgcc gccctgcaaattgggcaagggcgttttcaggttagcgcagaagatgccgaaggcttcaat gagaaaaactatgtgagctggtggccgaaaggcggtaaatcgaccagccctggacacatt tttaatgtttccactgaggaaaacccagacgtgagtctacgttggcgtgatctcagccag ccggcttctcagaatgagacgctggcatttgatgtcggctctgaagaaggggataacttt ggcttgaaggatgggacatacaagctggagaaatttattgaaaaactacaggctgccaaa ggcgttgatgcaaaattcgaggatatcagcgagggctttgccatggctgcgctggctaac cctaacctgcttaaatcagccggtatacctgagcatatttcccgaccgtttatcgaacaa tgggaaaatggcaacattgacatgcaggacattggccgagattttgccgaagcactgcgg acagccgcgaaacagaaagtcacgcctgagctgactgaaaaacgcatcactaatatcatt cgtcagtttgccgaacgtgagttgagcgacattcaggatttcaaggccagcgaagccgat cagggacgtgtattccgcatcaatctggcaggtttggatactgcggcaatgcagacagaa tggaacaaaatcagccagaaccctgatgcccgctatcaaatattgaacggtaactgttca agtattgtagccaaagtgctcaaggcaggtggagccgataaagtgatcggtcatacatgg cggccaaattttggtatctggaccccaaccgaattattcaattatgcacagaaactgcaa gaagcgcagattgagataatagccaataagccgaaacgcattgtgggtgaagatctggaa gcgctcggccagccggataaaaaagacaacgtgctggaaaaagttgccattgacaacgac ggcaaaccaccgcgtgacagagagcccttcaatccggtaacccgcttcctaaacaatgag ctttacggcgctaaggaagaacgccgcaatgtgtatgattacactcaaacggcgctggac acggctgtgaccaacggcacggcggataaagtcacgttacggggcgacgcagggcgtctg accggttattaccatcagggcgaacagaaaactgatgcgtcagccgaaccgaatacagcg aaaaaagtagtcctgttcattcatggttctggctcctctgcggaagaacaagccagtgtc atcaagaatcaataccagaagcagggtatcgatatgctcgcagtgaacctgcggggttat ggttccagtgatggccgtccgagcgaaaaagggctgtatcatgatgcccgcacgatgttc cgttatttggtcaatgatcgcggcgtcaggccggaaaatatcattattcatggctattct atgggcgggccaattgcggctgatcttgcccgttatgccgaacggaacggacacaccgtt tctggcctgctgctcgatagaccaatgccaagtatgaccaaagcgattactgctcacgaa gtgccaaacccagcaggaatgacgggcgtactggcaaaagcggtcaatggtcagttctca gtagagaaaaacctgcaggggagctcgaagcaaaccccaatcatgttgttgaccgataat gaaggcttgggtgaagcgggagaaaaactgcgcgctaaactggttattgatggctatcag gtatcgggtgaacataccttctatagtcatgaggccagcagccggttgatgaaccaatat gctgaacagattgtgacaggtttgtttgatgtgaagcgtcagccggatgaatcaacggca cttaaaggtctcaggagtgatctgaagcgctatggtgaagcgctggaacctcagaaaagt gcaccgggtaaaacgaaagatatccgtgcgacgcaagactttcttaccggttatcagcaa gggcatgcagagcagaccgttgatggtttccgttcagacatgaatatcaaacaactggtg gatctgctggttaaaggtaactggacagcagaacagaaaggctcactggcctgggaaatt gagagcagagccttgaaggtgaccttccagcctcaggcggagaagcacaatcggctattc aatgacgttgtttcgtccggggtggctgataccaaagcgagcaagcatcttgcaccacaa ttgttgttattgaacctgtcgaatgacggctttggcggacgttgtgacccattgtcgaaa ctggtgctggttgcgaaacaactggaaaacaatggtcaggatggcgttgcccgtaaactg ctggaaaaaatgtattctgcggctgcggtacttagcaatccaacactgtattcagacact gaacgcggcaatgccaacaaactattgggttctctggctgcccttcatgcccggaacccg atgcatgacacttccataaaggtgtggcaggagaagctggaagataagcaggccttgacc gtcaatggcgtgattgggaaagtgactgccgcaaatgccgatggcaaacctgttttgctt gagctggatgcaccaggccatgcgatggctgcatgggcgaaaggcagtggtgataatcgc gtttatggtttctacgatccgaacgcgggtattgtcgaattttcatctgcggagaaattc ggcgattaccttactcgtttcttcggcaaatctggcctgaacatggagcaaagctacaaa ctgccaaaaaatgccgcgggtgaaattatcttcaaacgtgtggtggtgatggatggcagc gtactggcgacttacaacccgacaagggctgacaagaccaccatgcagggtatccttgat ctgaatatttttgatgagacgccaataaaaacccattcagatgtggaaattacccatgag gtgaaagtccccctcaaggacaatctaccggaaggcgttgaccgtgtggttaacaacgag aatgtcgaacattgggagccggcttttgtcaaaccacaggcagaagggggtgacagtcgc tttaacagtcaggtcatcatccagacggaaaatgatcctgtcgcagctaaggctgccgca cgtctggccggtaaacatcctgattcaagcgtgattgtgcaacttgatgccaatggccga tatcgagtggtgtatggtgatcctgcgacgttgtccggcaaactgcgctggcagatcgtc ggacatgggcgtgatgaatcagtacagcaccacactcgtatgagtggctacagtgctgat gaactcgcgttgaaactaaaacagttccgtaccgacttcaagcaggccggttcgcctgat catatcagtcttgtcggttgttctttgatcagcgatgataaacgcgatggctttgcccgt cactttatctcagagcttgataagcagggcatccgaaccacggtatctgcccgcagcagc gaggttgcggtagacagcattggtcgtaaatttacacgtaatgccgaagaacagtgggtt cataagctcatggacaacaagattgttctgggctggaatgacaagggagagctggaaacc cacgctgaacggatccgccgtggcatctctgaaaacgacattaatttgtcccgtatcggt cacatcgatactgatgcgaaagcgaaaggcgcgattgcagaaaatgcagaaacattccac gccccggaacagcacaagaaggtgaatgatgatgcatcagccacgtcatcggcgaagtca tccaacaataaactgagctattccggcaatattcaggtacaggcgggtgatggcgaattt accgtcatcaactggggaacgaccaacgtcggtatcaaagtcggtacaggtggcttcaag tcactggcttttggtgataacaacgtcatggttcacctgggtaacggtgatagcaaacac agcgtcaatattgccggttatcaggcactggaaggcgcgcaactctttatgggtaaccga aatgtcagcttcaatatgggacgcagcaacgatctgatcgtgatgatggataaatccatt ccaactcccccgttggtcaatccatttgatggggcttcccgtatatctggtgtcttgcag aacattgccggctcctttgagtcaccagattggctgaccgcccaagatcagcagtggaca ctggagagtgcgaaaaaatacgtcagcgatctgtcaggtctcgatctgaccagcagtgtt gattacaacactctgaccgatctcgatacggagaatgaaaaaagcagtcgtggcctgaaa agtgatatcgaaaccacactgaacaagaaatacaatcagtggttgggcaggaacggtaat gctcgtgaaatgggtaacgtcagtcgggcggataaattccgtcaggagaatgaaacgctg gcctttaacttcgccgttggcgggcagggtgctgatattcaggtaacaacaggtaactgg aactttatgtttggtgacaatatccaatcgatcctggataccaacttgggttcactgttt ggcctgatgacacaggaatacacttccacgggtatggctaaaaccacgtttactttcagt ccgaaggacttaccacgccagcttaaaaacaagctgctcggcaatctggcgggtgtcagt gcagatacgacactggcagatatctttggtgttgactacaccgcggatggtcatattgtt tcccgttctggtcaatcggttgatggtgttgcgattctgcgtgaaatgctggaagtgatc ggtgaattcagtggtaatcaactacaggcatttactgatccggcaaaactgctcgacagc ttggaagccgggctgaatacaggggcagatggtgttaaatcttttgcggaaagccacggc ctgcaagcaaaagcgcctgaggaaaacaaagaagggcatgtgtcaatcagtacagagggt aaacctgttcaggaagtcgcagaattaccatcagatcgtgcccttggctttaacctgcca agcctgttcacaaccttgttcaagcagaataaacaggttgagatggcatcactggtcgct gatctgaaacagaatctgaccgctgatttgctgaacatacaggacaaaacgtttgacttt ctgcgtaacagcggccatctgcaaggtgacggtgatatgcatgtctctctcggtaactat aactttaactggggcggagatggcaaagaccttggcgcttatctgggggataacaacaac ttctggggcggtcgtggtgatgacgtttattactccgtaggaacctccaatatcttcacc ggtggtgaaggtaatgatatgggtgttctgatggggcgtgagaacatgatgtttggtggt gcgggcaatgacgttgctgtactggccggacgcattaactacgcctacatgggcgacggt gatgatcaggtctttgtcttcggtgaaggtggtgtgattgagggcggcaaagggcgcgac tatatcgtggcttccggtaatttcaatagcatccatgcaggagaaggacaggattatgtt gttgccattggtaacaacaatcaggtgagtttgggggaaggcgacgactttgccaccgta ttcggcaactataacaacattgatggcaacgccggcaataacgcgatcaaactgatgggt tatcacgcggtgatcaatggcggtacgggtgacgatcacctgattgccaatgtagcctcc aagttcagccaattgaacggcggcgatggcgatgacctgctggtactgggcggataccaa aacaacttcaagggtggcacgggcgttaatagctttgtggtcagcggggatgtgattgac aacgtggttgaagatatcaaacgcggcgacaagatcattttcaacaacctcaactggcaa aagctgtggttccagcgcagcggttacgatttggttctgctgactggccgtgatgtgaca gacacctcagcacaagggaagtttgaggcgataggttctgtgaccttcaacgattacttc aatggcaaccgtgcggatattgtcacccaaatgggagacaaagatacacagggtgaacgt gaatatacggcgctctctgccaattcggtggattcgttggttcaggcgatgagcgggttt gcaccaaatatgggcgacaccggctttattgatacacttgatagccagacgaaatcgact attgtgaccgcttgggcggacaccacaagcggaaaatccaaactggcctga

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