Xenorhabdus budapestensis: HGO23_03485
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Entry
HGO23_03485 CDS
T07176
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
xbu
Xenorhabdus budapestensis
Pathway
xbu00260
Glycine, serine and threonine metabolism
xbu00261
Monobactam biosynthesis
xbu00270
Cysteine and methionine metabolism
xbu00300
Lysine biosynthesis
xbu01100
Metabolic pathways
xbu01110
Biosynthesis of secondary metabolites
xbu01120
Microbial metabolism in diverse environments
xbu01230
Biosynthesis of amino acids
Module
xbu_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
xbu_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
xbu00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
HGO23_03485 (thrA)
00270 Cysteine and methionine metabolism
HGO23_03485 (thrA)
00300 Lysine biosynthesis
HGO23_03485 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
HGO23_03485 (thrA)
Enzymes [BR:
xbu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
HGO23_03485 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
HGO23_03485 (thrA)
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Paralog
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
PEG10-RTL1_C-capsid
Motif
Other DBs
NCBI-ProteinID:
QTL40471
UniProt:
A0ABX7VKN5
LinkDB
All DBs
Position
complement(798884..801343)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANYQRVLSVADIAESELSLGQVALVLSAPAKITNHLVAMITKTVAGQDI
VSNMSDTTQIFTDLLSGLKEHQPNFDYEHLKGVMERELANLKQTLHGISLLRQCPDSINA
ALICCGEKLSIAVISAVLQARGHQVFVIDPVKSLLAHGHYLESTVDIHESTKRIAALNIP
ADHIILMAGFTAGNDNGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRSV
SDARLLKSLSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTANPNAAGTFIGEGQK
DESMLIKGITNLNHMAMINVSGPGMKGMVGMAARVFAVMSRSGISVVLITQSSSEYSISF
CVPQKELNRAQKALTEEFYLELKDGVLDPIDVIDNLAIISVVGDGMRTQRGISARFFSAL
TRANINIIALAQGSSERSISAVIDNDAATTAVRLCHQMLFNTAQMVEVFVVGVGGVGSAL
IEQIRRQQSWLKQKHIDLRVCGIANSRAMLTDMQGISLDNWQQALSEASEPFSLSRLIRL
EKEYHLLNPVIVDCTSNQSIAEQYASFLSDGFNVVTPNKKANTLSMAYYREIRQAAEKSK
RKFLYDTNVGAGLPVIENLQNLLNAGDELVQFNGILSGSLSYIFGMLDEGMTLSQATLLA
KEKGFTEPDPRDDLSGMDVARKLLILARESGYELELEDIHVEPVLPASFDAGGNISDFLQ
RLPQLDLEFNRRVADATEQEKVLRYVGIIEQGRCMVKIAAVDGNNPLYKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADILRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtactaaaatttgggggcacttcagtcgcaaactaccagcgcgtactgagtgtg
gctgatatcgctgaaagtgaactatcccttgggcaagtcgccctggttctttctgcaccc
gcaaaaattacaaaccatttggtagcgatgataaccaaaacggttgcaggacaagacatt
gtttccaatatgagcgataccacccaaatctttactgatttgctatcgggattaaaagaa
catcagccaaatttcgattatgaacatctgaaaggtgttatggagcgtgagcttgctaat
ctaaaacaaaccctgcatggtatttctctattaaggcagtgcccagacagcattaatgca
gccctgatttgctgtggtgaaaaattatccattgctgttatatccgctgtactacaggct
cgcggacatcaagtatttgttatcgatccagttaaaagccttcttgctcacgggcactat
ctcgaatccactgttgatatccacgaatccaccaagcgtattgcagcactgaacattcct
gctgaccatattattctgatggcaggcttcactgccggtaatgataatggtgaattggtt
gttcttgggcgtaatggttccgattattcggccgcagtgctggcagcatgcttacgtgcg
gattgctgtgaaatctggactgacgtagatggtgtttatacctgtgacccccggtctgtc
tctgatgcccgtctattgaaaagcctgtcctatcaggaagcgatggaactttcctatttt
ggagccaaagttcttcatccccgtactattgcgcctatcgctcaattccaaatcccttgc
ctgattaaaaatactgccaaccctaatgcggcaggaacattcattggtgaagggcaaaaa
gacgaaagtatgcttatcaagggcatcactaacctgaaccatatggcaatgatcaacgtt
tcaggccccggcatgaaaggtatggtcggcatggcagcaagagtatttgccgttatgtcc
cgctcaggcatttctgttgtactgattacacagtcttcatcggaatacagcatcagtttc
tgtgtaccgcaaaaagagttgaacagagcacaaaaagcactgacagaagaattttatctg
gaattgaaagatggagtgcttgatcccattgatgtgatagataacctcgccatcatttct
gtggttggtgatggaatgcgtacacaacgtggcatctctgcccgtttcttctcagcattg
acccgtgccaatattaacatcatcgcccttgctcaaggttcatcggaacgctccatctcc
gcagtcattgacaatgatgctgcgacaacagcggttcgtctctgtcaccaaatgctgttt
aatactgctcaaatggttgaagtgtttgttgtcggtgtgggtggtgtgggcagcgcattg
attgagcaaatccgccgccaacaatcatggctgaaacaaaaacatattgatctccgcgta
tgcggtattgccaactcgcgggctatgctaacagatatgcagggcatcagtttagataac
tggcaacaggctctatcagaagccagtgagcctttcagcctgagccggttgatccgcctc
gaaaaagagtatcatctcctgaacccagtgattgtggactgtacatcaaatcaatccatc
gccgaacaatatgccagcttcctgagcgatggcttcaacgttgtcacaccgaataaaaaa
gccaatacactttcaatggcctactaccgtgaaatccgtcaggctgctgaaaagtcgaag
cgcaagttcctgtatgacaccaacgtaggcgcgggattgcctgtcatcgaaaacttacag
aatctgctgaatgccggggatgagttagttcagttcaacggtatcctgtcaggctctctg
tcttatattttcggtatgttggatgaaggtatgacactttcgcaagcaacgttgctggca
aaagaaaaaggctttacggaacccgatccacgagacgatctctcaggtatggatgttgcg
cgtaaactattaattctggcccgtgaatctggctatgaactggagttggaagatattcac
gtcgagcccgttttaccggcatcatttgatgccggtggtaatatcagcgatttcctgcaa
cgtttaccacaactggatctggaatttaatcgtcgggttgcagatgccacagagcaagaa
aaagtgttgcgctatgttggcattattgaacaaggccgttgtatggtgaaaattgccgca
gtcgatggcaataatccactttataaagtcaaaaatggcgaaaacgccctggctttttat
acccgttattatcaaccaatcccattggtgctacgtggctacggtgcagggaatgatgta
acggcagcaggcgtttttgctgatatattacgcactctgtcatggaaattgggggtttaa
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