Xenorhabdus doucetiae: XDD1_0780
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Entry
XDD1_0780 CDS
T03784
Symbol
thrA
Name
(GenBank) Bifunctional aspartokinase/homoserine dehydrogenase 1 [Includes: Aspartokinase; Homoserine dehydrogenase]
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
xdo
Xenorhabdus doucetiae
Pathway
xdo00260
Glycine, serine and threonine metabolism
xdo00261
Monobactam biosynthesis
xdo00270
Cysteine and methionine metabolism
xdo00300
Lysine biosynthesis
xdo01100
Metabolic pathways
xdo01110
Biosynthesis of secondary metabolites
xdo01120
Microbial metabolism in diverse environments
xdo01230
Biosynthesis of amino acids
Module
xdo_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
xdo_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
xdo_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
xdo00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
XDD1_0780 (thrA)
00270 Cysteine and methionine metabolism
XDD1_0780 (thrA)
00300 Lysine biosynthesis
XDD1_0780 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
XDD1_0780 (thrA)
Enzymes [BR:
xdo01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
XDD1_0780 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
XDD1_0780 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
CDG16483
UniProt:
A0A068QNH6
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All DBs
Position
complement(747315..749804)
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AA seq
829 aa
AA seq
DB search
MRVLKFGGTSVANHQRVLSVADIAEHELSLGQVALVLSAPAKITNHLVAMIEKTVAGQEI
VSNMSDASQIFADLLSGLKEQQTGFDYKRLKGMVERELASLKQTLHGISLLKQCPDSINA
SLICRGEKLSIAIMEAVLQARGHQVTVIDPVKNLCAHGHYLESTVDIHESSKRIAELNIP
ADHIILMAGFTAGNESGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRAV
KDARLLKSLSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTANPDAPGTFIGDTLI
DNALIDHEQKDQNMPIKGITNLNHMAMINVSGPGMKGMVGMAARIFSVMSRKGISVVLIT
QSSSEYSISFCVPQKELVNAQKALTEEFYLELKDGVLDPIDVIDNLAIISVVGDGMRTQK
GTSARFFSALTRANINIIAIAQGSSERSISAVIDNDAATTAVRLCHQMLFNTAQVVEVFV
VGVGGVGSALIEQIRRQQTWLKQKHIDLRVCGIANSRALLTDMQGISLDNWQQALSEATE
PFSLSRLIRLEKEYHLLNPVIVDCTSNQSIAEQYASFLGDGFNVVTPNKKANTLSMAYYR
QIRQAAEKSKRKFLYDTNVGAGLPVIENLQNLLHAGDELVQFSGILSGSLSYIFGMLDEG
MTLSQATLLAKEKGFTEPDPRDDLSGMDVARKLLILAREAGHELELEDIHVEPVLPLSFD
ASGDIDSFLQRLPQLDQAFSQRVKEAAEQEKVLRYVGLIEQGRCTVKMVAVDGNDPLYKV
KNGENALAFYTRYYQPIPLVLRGYGAGNDVTAAGVFADILRTLSWKLGV
NT seq
2490 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtattgaaatttggaggaacctcagtggcgaatcaccagcgcgtactgagcgtc
gcagatatcgccgagcacgagttatcccttgggcaagtggccctggtcctctcggctccc
gcgaagatcaccaaccatctggtggcgatgattgaaaaaacggttgccgggcaagagatt
gtttccaatatgagcgatgccagccaaatctttgctgatttactgtcaggattgaaagag
caacaaaccgggtttgattataagcgcctgaaaggaatggttgagcgtgaactcgccagc
ctgaaacagacgctgcacggcatttccctgttgaaacaatgtccagacagcattaacgcc
tccttgatctgtcgtggtgaaaagctatcgattgccatcatggaagcggtgctacaggca
cggggtcatcaagtcacggtcattgatccggtcaaaaacctgtgtgcacatgggcattat
ctcgaatctaccgtcgatatccatgaatcgtccaaacgcattgccgaacttaacatcccg
gctgaccacatcatcctgatggccggcttcacggcgggtaatgaaagtggcgaactggtc
gtattggggcgcaacggctctgactattcagccgcagtactggcagcctgcctgcgagcc
gactgctgtgaaatctggacggatgtcgatggtgtttatacttgtgatcccagggcggtt
aaagatgcacgcctgctaaaaagcttgtcatatcaagaagcgatggagttgtcttatttc
ggcgcgaaagtgcttcatccccggactatcgcccctatcgcccaatttcaaattccttgc
ctgataaaaaacaccgccaaccccgatgcgccggggacgtttattggtgatacgctgatt
gataatgctcttattgatcatgaacaaaaagatcagaatatgccgattaagggcattacc
aatctgaaccatatggcgatgatcaacgtgtccggccccggcatgaaagggatggtcggg
atggcggcacggatcttttccgtcatgtcgcgcaaagggatttccgtcgtgttaatcacc
cagtcctcgtcagaatacagcatcagtttctgtgtcccgcaaaaagagctggtcaacgcg
cagaaagcactgaccgaagaattttatctggagctgaaagatggtgtgcttgatcccatt
gacgtgatcgacaacctggccattatttctgtcgtcggggatgggatgcgtacccagaaa
ggcacttccgcccgctttttctccgcattgactcgtgccaatatcaacatcattgccatt
gcgcaaggctcttctgaacgctccatttctgccgtcattgacaatgatgccgcgacgacg
gctgttcgtctctgccaccaaatgctgtttaacaccgcccaagtggttgaagtgttcgtt
gtcggtgtgggcggcgtaggcagtgcgttaatcgagcaaattcgccgtcagcaaacttgg
ctcaaacagaaacacatcgatctgcgcgtctgtggtattgccaattcccgtgctttgttg
acggatatgcagggcatcagtctggataactggcaacaagcactttcagaagccactgag
cctttcagcctgagtcgcctgatccgccttgaaaaagagtatcacctcctgaatccggtg
attgtggactgtacgtctaatcagtcgattgcggagcaatatgccagcttcctcggcgac
ggttttaacgttgtcacccccaataaaaaagccaatactttgtcgatggcttattaccgc
caaatccgtcaggcggcagaaaaatcgaaacgcaaattcctgtacgacaccaatgtcggg
gcgggcttgccggttatcgaaaacttacaaaacctgctgcatgccggtgatgaattagtc
cagttcagcggtatcttgtcgggttccctatcctacattttcggcatgctggatgaaggc
atgacgctctcacaagcgaccctgctggcaaaagagaaaggctttaccgaacccgatcca
cgggatgatctctctggcatggacgttgcccgaaaactgttgatcctggcgcgcgaggcg
ggccatgagctcgagctggaagatatccatgtagagcctgttttacccctctcgttcgac
gccagtggtgatattgacagctttctgcaacgtttaccgcaactggatcaggcatttagc
cagcgtgtaaaagaggccgcagaacaagaaaaagtgttacgttatgttggcttgattgag
caaggccgttgtacagtgaaaatggtcgctgttgacggcaatgatccactgtataaagtt
aagaacggcgaaaacgcgctggctttctatacccgttattatcaacccattccgctagta
ttgcgtggttatggcgcagggaatgatgtcacggctgccggcgtttttgctgatatatta
cgcactctatcatggaaattgggggtttaa
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