Xiphias gladius (swordfish): 120788987 Help Entry 120788987         CDS       T07311                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism xgl  Xiphias gladius (swordfish) Pathway xgl04020   Calcium signaling pathway xgl04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:xgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     120788987 (ryr3)    04020 Calcium signaling pathway     120788987 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:xgl04040]     120788987 (ryr3) Ion channels [BR:xgl04040]  Voltage-gated cation channels   Ryanodine receptor    120788987 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 Med16_bridge Motif Other DBs NCBI-GeneID:  120788987 NCBI-ProteinID:  XP_039981292 LinkDB All DBs Position LG4:6747677..6865397 Genome browser AA seq 4852 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQSVATIQKEHRKFCLAVEGLGNRICYLESTSEAKYVPP DLCICNFVLEQSLSVRALQEMLANTGQNSEGSADHEKWAGQGGGHRTLLYGHAILLRHSF SGMYLTCLKTSRSLTDKLSFDVGLQEDSIGEACWWTIHPASKQRSEGEKVRIGDDLILVS VSSERYLHLSISNGNIHVDASFMQTLWNVQPTCSSSNKAVGYLIGGHVLRLCHGHDESLT IPGADKTEEEQRTVNYEAGKGASKARSLWRLEPLRISWSGSHIRWGQAFRLRHLSTGHYL ALTEDRGLVLQDREKSDTTATAFCFRASKEKVDSGPKRDIEGMGVPEIKYGDSVCFIMHV ATGLWLSYQAPDAKSSRLGTLKRRACLHLEGHMDDGLTLQRCQHEESRAARIIRNTTLLF TNFIKALDSIAEGESMAVAGYVEEVLQTLNDLIEYFKQPDSELEHEEKQCLLRSLIKRQD LFKEEGMLALLSKCIDRMNLYNSAAHFGEMAGEEAGAAWKDILNLLYELLASLIRGNRNN CTQFSRNLDWLVSKLERLESSSGILEVLHCILVESPEALNIIQRGHIKSIISLLYKHGRN HKILDVLCSLCVCNGVAVRANQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLGVAEGS AQYKKWYFELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYSF DGLHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTDGF FFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVEPVKEYKRDLEGI RDLLGTTQFLSQASFIPTPVDTTQIVLPPHLDSVRDKLAENIHELWGMNKIELGWTYGKV RDDNKRQHPCLVDFVKLPETERNYNLQMSSETLKTLLALGCHVAQVNIHAEDDLKKIKLP KDYMMSNGYKPAPLDLSDVKLTAGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSR RNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYDIDPPDQEVIHVMDDQSIETIRFFR VEQTYAVKTGKWYFEFEALTGGDMRVGWARLGCRPDVELGVDDQAFVFDGYRGRRMHKGS RYFGHPWKKGDVVGCMINMEDKSMIFTLNGELLITNKGSELCFADFETEDGFIPVCSMGM SQIGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREITMWFSKRLPTFVNTPRDHMHIE VTRIDGTVDSPPCLKVTHKTFGTQNSNNDMVYCRMSMPVEFYSADMLLDESLKLSHPPKE DGTVDFGSITTYYHSVRVFAGQDPASVWVGWVTPDYHYHSKNFSLSKTRTVTVTLGDERG RVHESVQRSNCYMVCGADAVGPSSSSRSNSDLEIGCLIDLATGLVSFTANGKELLTTYQV EPNTKLFPAVFVRPTSANLFQFEFVKIKDAMPLSSAIFKSEHRNPVPQCPPRLDVQTIVA VLWSRMPNTFLSVETARVSERHGWVVQCLEQLQMMAVHIPEENRCLDILELSELEDLRKF HYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNVLMSIHLET AKEARLMMNNEFIIPVTEETRSIKLFPDESKRHSLPGVGLSTSLKPRVNFSPVGIINTKR HQYLHSPQIPLGILKEKAISMLTEAVQGGGTHIRDPVGGSVEYQFVPILKLIGTLLIMGV LTSEEVRLILLLIDPNVFGEAKEGEEGKGDEVALAGEKEEVSKNEEKAVEAGEEETKESK PPAKGLLEKSLPESVKRQMCELLHYFCDCELKHRIEAIVSFSDRFVSKLQYNQKFRYNEL MQALNMSAAVTAKKTKEFRSPPQEQINILLNFSAGDDCPCPEEIQYELISFHEELRLHCG IPVEEEEEEQDTSIKGRLLALLYKIKGPPHKTEEEPTETEQAAPTNLKELISQTITSWAQ ESHIQDPELVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDAINLLASLGQIRSLLS VRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIAFPK MVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVMDNN GLALALEEPDLEKVVTYLAACGLQSCAMLVAKGYPDLGWNPIEGERYLSFLRFAVFCNGE SVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISDDPALDLPKTPTGVTTG SGEEEGEVIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPTKDLV GVISIPLKVPVVNKDGTVTEPDMSACFCPDHKAPMVLFLERVYGIEDQSFLLQMLEVGFL PDLRASASLDTEVLSTTETALAMNRYIGSAVLPLLTRCAALFASTEHYAQLIDSTLHTIY RLSKGRSLTKAQRDAIEDCLLAICKHLRPSMMQQLLRRLVFDVPLLTEYCKIALRLLTHH YEQNWKYYCLPSGMGSFGTASEEELLLTKKLFWGIFDSLSQKKYDAELFKMAKSCLCAIA GALPPDFVDVSPGATLEKQTSVDAQGNFDPIPINTANISVPEKLEYIANKYAEHSHEKWS SEKVSAGWKHGDGMDEQAKTHPLLKPYKALSEKERETYRWPVRESLRSMLAMGWNIERTK EGEAMFQQRESEKQRKISESQVNGFSPAPLDLRNVTLSRELQGMVEVVAENYHNIWAKKK KTELVSKGGGTHSLLVPYDTLTAKEKYRDREKAQELFKFLQISGYAITRGLKDMEQDSSS MEKRFLFKFLKRLLKYIDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLTDQTF KNHCLYFLSTPSKNLSVCGCASNKEKEMITSLFCKLAALVRHRISLFGSDSAMMVSCLHI LTHSLDTRTVMKSGSELVKAGFRTFFENAAEDLEKLLEMLKLGKFMQSRAQIKSVSQSIN YVTVALLPILTALFDHIRTYEFGVDLLLDDVQLSCYRILTCIYSLGTGKNVFVERHLPAL GESLATLVGAIPVAFLEPHLNAHNPLSVFNTKTPRERAILSMPDTVEEMCPEMPRLDRLL KDVSDVSESGARYSDMPQVIEVILPMLCNYLSYWWEKGPENSPPGAQCCTTVTSEHLSII LGNILKILNSNLGIDDAPWMKRIAVYSQPIICKAGADLLRTHFLPTLDKLKKKTVKVVVE EELLKADSKGDNQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRWLKEPDADSTELF RMVADIFILWCKSHNFKREEQNFVVQNEINNLGFLTGEGKTKMSKSGGDQERKHKRRRGE YYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKEHLRQNLHLQD KSDDPAVQWQLDLYKDVVVKSEEPAEPEHTVDRVQSISAAVFHLEQVEQPLRNKKCVWQR LLSKQRKRAVVACFRMAPLYNLPRHRSINLFIPAYQRLWIEAVENSFEEKLVQDLAKTPM KIVEEEEEEVAEIQPDPLHQLILHFSHNALTERSHLDEDPLYIAYADMMAKSCAEDEEEE EEEGKEKTFEEKEMEKQKTLYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLKLGISI LNGGNVQVQQKMLDYLKEKRDTGFFKGLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGS IHTERGSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTVDYLLR LQESISDFYWYYSGKDVIDETGKVNFSKALSVAKQIFNSLTEYIQGPCIGNQQSLAHSRL WDAVVGFLHVFANMQMKLSQDASQIELLKELMDLQKDMVVMLLSLLEGNVVNGTIGKQMV DTLVESSNNVEMILKFFDMFLKLKDLTTSDNFKEYDPDCKGIISKKEFQKSMESQKQYTQ SEIDFLLSCAETDENDMFNYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSRLGTFLD LAESVLNYFEPYLGRIEIMGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEG GESEKMEMFVNFCEDTIFEMQLASQISEPDAVEQPEEEEEEDGHSILEELAGEEEGALES ASAFTTACCSVKKKFASVRQIISVKNIRKQFKKIRKLTIKEIITGFFSFFWMLFTGFFKG IYGLIFGFFHVIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVIEGEKAEAIES SGSLDKAMAPSGDIAEVDVMLEMLTVPKKEGGKHMEPGLGDVSELSTEMSTTDQKKKASA KPVETPESEPEKADTENREKEDKPKEEEAKEPATEEKPKTRLGQPKEAAPAFMSTIFAVL DIYLTKTLNYLARNFYNLRFLALFVCFAINFILLFYKVTDEADEEMDDENDADDHDVDTL FDMDEFVLQESTGYMLPTLRFLAVFHTVISLLCVVGYYCLKVPLVVFKREKEIARKLEFD GLYITEQPSDDDIKGQWDRLVINTPSFPSNYWDKFIKRKVINKYGDLYGAERIGELLGLD KSALDFDPTVEAVEKEASLLSWLSSIDTKYHIWKLGVVLTDNSFLYLIWYTTMSIFGHFN NFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNK SEDEDEPDMKCDDMMTCYMFHMYVGVRAGGGIGDELEDPAGDPYELYRILFDITFFFFVI VILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEHNL ANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPTGDCFRKQYEDQLG NT seq 14559 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggggaagatgagatccagttcttgagaactgatgatgaggtg gtgctccagagtgtggccaccatccagaaggagcatcgaaagttctgcctggctgtcgag ggactcggaaaccgtatatgttacctggaatcaacatcagaagctaagtatgttcctcca gacctgtgtatttgtaactttgtgttggagcagtccctgtcagtgcgggccctgcaggag atgctggctaacactgggcagaacagcgaagggagtgctgaccatgaaaaatgggcaggt caggggggcggacaccggacccttctctatggtcatgccatcctccttcgccactccttc agtggcatgtacttgacctgtttgaagacatcaaggtctctgacagacaagctgtcattc gatgtcggactacaggaagattcaataggagaagcctgttggtggaccatccaccctgcg tccaagcagagatccgagggagagaaagtccgcatcggagacgacctgattcttgtcagt gtgtcatcggagagatacctgcacctctctatctccaatggcaacatccatgtggatgcc tccttcatgcaaactctgtggaacgtccagcctacctgctcctcaagcaacaaggctgta ggatatttgattggtggacatgtgttgcgtctttgtcacgggcatgatgagagcttgacc atccctggagcagacaagactgaggaggagcagaggacagtcaactatgaggcgggtaag ggagcgtctaaggcccgctcactgtggagactggagcctctcaggatcagctggagcggt agccacatccggtggggccaggccttcagactacgtcacctctctactggccattacctg gccctgactgaggaccgtggactggtcctgcaggacagggagaagtctgacaccacggcc actgccttctgcttcagggcctccaaagaaaaggttgactcgggcccaaagagggacatt gagggcatgggagtgccagagatcaagtatggagactctgtctgctttatcatgcatgtg gcgacaggactgtggctgtcctatcaggcacctgacgccaaatcgtctcgcctaggaacc ctgaaaagacgggcctgcctacatttggagggccacatggacgacgggctgaccctgcaa cgctgtcagcatgaggagtctcgggccgcacgcatcatccgcaacaccacgttgctcttc accaacttcatcaaggctttggacagcattgcggagggtgagtccatggcggtggctggg tacgttgaagaggtgctgcagacgctgaacgatctgatcgagtacttcaaacagcctgac tcagagctggagcacgaggagaaacagtgtcttctccgttcgctcatcaaacgtcaagac ctcttcaaagaggagggtatgctggccctcttgtccaaatgcatcgaccgaatgaacctg tacaacagtgctgcccactttggagagatggctggggaggaagcgggcgctgcctggaag gacattctcaacctcctctatgagctgctggcctcactgattcgtgggaacaggaacaac tgcacccagttttcccgcaacttggactggctggtcagcaaactggagagactggaatct tcctcagggatcctggaagtcctccactgtatcttggtagaaagcccagaggctctgaac atcatccagagagggcacattaaatccatcatctctctgctctacaagcatggacgcaac cacaagattctggatgtgttgtgttccctctgtgtttgtaatggggtagcagtgagagcc aatcagaatctgatctgtgacaaccttctccccaaaagggatctgctgcttcagactcga cttgtcaatgatgttcagagtatgagaccaaacatcttcctgggcgtggctgaaggttca gctcagtacaagaagtggtatttcgagctggtgatcgaccaggtggaccactttgttacc ggagagccgactcacctgagggtgggctgggccaacactaaaggctacgctccgtacccg ggtggaggagagggatggggaggcaacggtgtcggggatgacctgtactcctacagcttt gatggacttcacctctggtcaggccgaatcccaagggccgtggcatccatcaaccagcac ctgctgaactcagacgacgtggtcagctgctgtctggatttgggcgctcccagcatgtcc ttcaggatcaacgggcagcctgtccagggcatgttcgaggacttcaatacagatggattc ttcttccccgtcgtcagcttctctgcaggtgtcaaggtacgtttcctgttgggtggacgc cacggagatttcaagttcctgccgcccgctgggtactctccatgctatgaggcgctgttg cccaaagagaagatgcatgtagagcctgtgaaggagtacaagagagaccttgaggggatc cgtgacctgctgggaaccacccagttcctctctcaggcttccttcatccccactcctgtt gacaccacccagattgttcttccccctcacctggacagcgtccgggacaagctggcagaa aacatccacgaactgtgggggatgaacaagattgaactgggctggacctatggcaaggtt cgcgatgacaacaagaggcagcacccttgccttgtggatttcgtcaagctgcctgaaact gaaaggaactacaacctgcagatgtctagtgaaacacttaagaccctgttggcactggga tgccatgttgcccaagtcaatattcatgctgaggacgatctgaagaaaatcaaactaccc aaagactacatgatgtctaatggatataagcctgcgccactggacctctctgatgtgaaa ctgactgcaggtcaggaggttctagttgataaactggccgagaacgcacacaacgtgtgg gccaaagacagaattaaacaaggatggacctatggcatccagcaggatttgaagagcagg cgtaatcctcgcctggtgccatatgctttactggacgaacgcactaagaaatctaacaga gacagtctgagagaggccatcaggaccatggttggatacggatatgacatcgacccccca gaccaggaggtcatccatgtgatggatgatcagagcatcgagaccattcgcttcttccgc gtggagcagacctacgcagtgaaaacagggaagtggtactttgagtttgaggccctgact ggaggtgatatgagggttggctgggccagactgggctgcagacctgatgtggaacttgga gtggacgaccaagccttcgttttcgatggatacaggggtcgacgtatgcataaaggcagc cgctactttggacatccttggaaaaagggcgatgtggttggttgcatgatcaacatggag gacaaatccatgattttcaccctgaacggagagctcctgatcaccaacaagggctctgag ctttgcttcgctgactttgagacagaggacggtttcatccctgtgtgcagtatggggatg tctcagatcggccgtatgaacctgggcaaggacgccagtacttttaagtactataccatg tgtggtctccaggaaggcttcgagccctttgccgtcaacatgaacagagagatcaccatg tggttcagtaagcgcctgcccacctttgtcaatacaccccgggaccacatgcatattgag gtgacgaggatcgatggaacggtggacagccctccctgcctcaaggtcacccacaagaca tttggcacccagaacagcaacaacgacatggtctactgtagaatgagcatgcctgtagag ttctactctgcagacatgttgctggacgaatccctgaaactcagccatcccccaaaagaa gatggaactgttgactttggaagcatcacgacttactaccactcggtgagagtgtttgct ggacaggaccctgcctcagtgtgggtgggctgggtcacaccagactatcactaccacagc aagaacttcagtctcagcaagacgcgaacagtaaccgtcactctgggagatgagagaggc cgagtccatgagagcgtccagaggagtaactgctacatggtgtgcggagcggacgccgtc ggcccgtcctcctccagccgctccaactctgacctggagatcggctgtctgatcgacctg gccactggcctggtctccttcaccgccaacggaaaggaactgctcacaacatatcaggtg gagccaaataccaagctcttcccagctgtgtttgtacgccccaccagtgcaaacctcttc cagtttgaatttgtcaagatcaaggatgccatgccgctctcatcagccatatttaagagc gagcacaggaacccggtgccacagtgcccgccgcgactggatgtgcagaccatcgtggcc gtgctgtggagccggatgccgaacaccttcctcagtgtggagacggctcgggtcagcgag aggcatggctgggtggtccagtgtctggagcagttacagatgatggctgttcatataccc gaggagaacaggtgtttggacatcctggagttatctgagcttgaggacctgcggaagttc cactaccacacgctgaaactgtactgtgcactctgtgccctgggaaacactcgcgtagct cacgccctctgcagccacttggaccaatcacagctcctctacaccatcgacaaccagtac ctctctggcatgctcagagagggcttctacaatgtccttatgagcatccatcttgagaca gcaaaggaggcccgcctaatgatgaacaacgagttcatcattcctgtgacggaggagacg cgctccatcaagctgttcccagacgaatccaagcggcactcgctccctggtgtgggcctg agcacctccctcaagcctcgggtcaacttctcccccgttggcatcatcaacaccaaacgc caccagtacctccatagcccccagatccctctgggcatcctgaaagagaaagccatcagc atgctcaccgaggctgtgcagggcggaggcacacacatccgagaccctgtgggtgggagc gtcgagtaccagttcgtccccattctgaagctgattggaacactattaatcatgggagtc ctaaccagtgaggaagtgaggctgattctcctcctgattgaccccaatgtgttcggagag gccaaggagggtgaggaagggaagggggatgaggtggccttggcaggggagaaggaggag gtgagcaagaatgaagagaaagcagtggaggcaggagaagaggagaccaaggagagtaag ccgccagctaaaggtcttctggagaaatcactgcccgagtctgtcaaacgccagatgtgt gagctgctgcactacttctgtgactgcgagctgaagcaccgcatcgaggccatcgtctcg ttctctgaccgcttcgtgtccaagctgcagtacaaccagaagttccgctacaatgagctg atgcaggcgctcaacatgtccgccgccgtcactgccaagaagaccaaagagtttcgttcc cccccacaggagcagatcaacatcctgttgaatttcagtgcaggggacgactgcccctgt cctgaggagatccagtatgaactcatctccttccatgaagaattgcgactgcactgtgga attccagtggaggaggaagaggaagagcaggacacttcgataaaaggccgtctccttgct ctgctctacaaaatcaagggtccacctcacaagacagaggaggaacccacagagacagaa caggctgctcccaccaacctgaaggagctgatctcccagaccataaccagctgggcccag gagtctcacatccaggacccggagttggtcagagtgatgttcagcctgctgaggaggcag tatgatggcatcggggagctgctccgggccatgaagaagtcctacactatcagcgctgca tccgtgcaggatgctattaatctgttggcatctctgggtcaaatcaggtctctgctgtcc gtgcgcatgggcaaagaggaagagaaactcatgattgatggactcggtgacatcatgaac aacaaggtcttctaccaacatcctaacctgatgagagtgctgggcatgcatgagactgtc atggaggtcatggtcaatgtgctgggaggagacaagtcacaggagattgccttccccaag atggtggccagctgttgtcgtttcttgtgctacttctgtcgtattagccgccagaaccag aaagccatgtttgaccacctgagctacctgctggagaatagcagcgttggactggcctct gaagcaatgcggggctccacgccgctggatgtcgcagcatcttcagtgatggacaacaac ggcctggctctggccctggaggagcctgatctagagaaggtggtgacatacctggcagct tgtggtcttcagagctgtgccatgctggttgctaagggttacccagacctcggctggaac cccattgagggagagcgttacctgtccttcctgaggtttgctgtcttctgcaacggtgag agtgtggaggaaaatgccaatgtggtggtgaaactgctgatcagacgcccagagtgtttc ggccccgccctgaggggagagggaggccagggtcttctggccgccatgaaggaggccatc aagatctcggatgatcccgccctggacttgccaaagacccccactggagtcactactggg tctggtgaggaagaaggagaagttatccacatgggcaacgccatcatgtccttctactca gctcttattgatctgctgggacgctgcgctccagagatgcatcttatcaatgcgggtaaa ggtgaggcgctgcgtatcagagccatcctgcgctctctggttcctaccaaagacctggtg ggcgtcatcagcatccccctcaaagtgcctgtggtcaataaagatggcacagtgacagag cccgacatgtcagcctgtttctgtccggaccacaaggcccccatggtgctcttcctggaa cgagtgtacggcatcgaggaccagagcttcctgctccagatgttggaagttggcttcctg cctgacctccgagcctcggcatctctggatacggaggtgttgagcaccactgagacggcg ttggccatgaacaggtacatcggctcagccgtattgcctctgctgacccgctgcgctgct ctctttgccagcacagagcactacgcacagctgatagactccacgctgcacaccatctac cgcctgtccaaaggccgctcactcaccaaagcccaaagggacgccattgaggactgtctg ctcgctatctgcaagcacctacgcccctctatgatgcagcagctgcttagacggctggtg ttcgacgttcccctgctcacggaatactgcaagatagctctccggctgctgacccaccac tatgagcagaactggaagtactattgcctgccatctggtatgggcagctttggcacagcc tctgaggaggagctcctcctcactaagaaactattctggggaatctttgactccctttct cagaagaagtatgatgctgaacttttcaaaatggccaagtcatgcctgtgtgccatcgct ggagctctgccccctgactttgtggatgtcagtcctggggcaacactggagaagcagaca tcagtggatgcacagggcaactttgaccccatacccatcaacactgccaatatctccgtt cctgaaaaacttgagtacattgccaacaaatatgcagagcattcccatgagaagtggtcc tcagagaaggtgtcagcaggctggaaacatggagacggcatggatgagcaggctaaaacc catccactgctgaaaccttacaaagctctgagtgaaaaggagagagaaacataccgttgg ccagtgagggagtcgttgaggagcatgttggcaatgggctggaacattgagaggaccaag gagggagaagccatgttccaacaacgagagagcgaaaaacaacgaaagatctcagagtct caggttaatggattcagtcctgctccgttggatctgcgtaatgtcactttgtctagagag ttgcagggcatggtggaggtggttgcggaaaattaccacaacatctgggccaagaagaag aaaaccgaactcgttagcaaaggaggagggacccactcgctgctggttccctatgacacg ctgacagctaaagagaagtacagggacagagagaaggcccaggagctcttcaagtttctg cagatcagtggctatgctatcacaagaggtctgaaggacatggagcaggactcatcatct atggagaagcgttttttattcaagttcctcaagaggctgctaaaatatattgactctgcc caggagtttattgctcaccttgaggccatggccaccagtgggaagacggacaaatcacct catgaccaggaaattaagttctttgctaaggtgttgcttcctctgacagatcagaccttt aagaaccactgtctctacttcctttccacacccagcaagaacctgagcgtctgcggctgt gcctccaataaagagaaggagatgatcaccagcctgttctgtaagctggcagctcttgtc agacacaggatttctctctttggcagtgactcagcaatgatggtgagctgtctgcacatc ctcactcactcacttgacaccagaacggtgatgaagtctggctcggagctggtcaaagcc gggtttaggaccttctttgagaatgcagcagaggacttggagaagctgctggagatgctg aaactggggaagttcatgcagtcccgtgcccagatcaagagtgtcagccagagtatcaac tatgtgactgtggcactgctgcccatcctcaccgccctgtttgatcacatcaggacatat gagtttggagtggacttgctgttggatgacgtgcagctttcctgctaccgtatcctgacg tgtatctattctctgggaacaggaaagaacgtctttgtggagaggcatcttcctgcactg ggggagagtctggcaaccttggtgggagccattcctgtagctttcctggagccccaccta aacgcccacaacccactctctgtcttcaacaccaagaccccccgagagagagccattctc agtatgccggacacagtggaggagatgtgtccagagatgcctcgtcttgacagactcctg aaagatgtcagtgatgtctcagagtctggcgctcgctacagtgacatgccacaggtcatt gaggtgatccttcccatgctgtgtaactatctgtcctactggtgggagaaaggtccggag aactcccctccaggtgcccagtgctgcaccacggtgacctctgaacacctcagcatcatc ctgggaaatatcctcaagatcctcaacagcaacctgggcattgatgacgcaccctggatg aagaggattgcagtctactctcagccaatcatctgcaaggctggagcagatctgctgaga acccacttcctgcccacactggacaaactaaagaagaagacagtgaaggttgtggttgaa gaggagctgctgaaggccgacagtaaaggtgacaaccaggaggccgagctgctcatcctg gatgagtttgctgtgctctgcagggacctctatgctttctaccccatgctcatccgttat gtggataacaacaggtctaggtggttgaaggagcctgatgcagactccactgagctcttc aggatggtggctgacatcttcatcctctggtgcaagtcccataactttaagcgtgaggag caaaactttgttgttcagaatgagatcaataatttgggcttcctgactggggaaggcaag acgaagatgtccaagtcaggtggggaccaggagaggaaacacaagcgtcgtcgaggcgaa tactactccatccagacctctctgattgtcgctgccctgaagaagatgctgcccattggc ctcaacatgtgcaccccaggtgaccaggagctcatctctttggccaagatacgctacagt ctgaaagacacagatgatgaggtgaaggagcacttgcgtcagaatctccatctccaggac aagtctgatgacccagcggtccagtggcagttggacctgtacaaggacgtggtggtgaag agcgaggagcctgcagagccagaacacacggtggaccgagtccagagcatctctgctgca gttttccaccttgagcaggtggagcagcctttgaggaataagaagtgtgtgtggcagagg ctcctgtccaaacagcgtaagcgtgctgtggtggcttgtttccgtatggctccactctac aatctacccaggcatcgctctatcaacctcttcatcccggcctatcagagactttggata gaggcagtggagaactcctttgaggagaagctagttcaggatctggcaaaaacccccatg aagattgtggaggaggaggaagaggaggtggctgagatccagcccgaccctctacatcag ctcatcctccacttcagccacaacgctctgacggagagaagtcacttggatgaagatcct ttgtatattgcgtatgcagacatgatggcaaagagctgtgcagaggatgaggaggaagaa gaggaggaagggaaagaaaagacatttgaggaaaaggagatggaaaagcagaagacccta tatcaacaggcgcggctacatgcccgtggggcagctgagatggtgctgcagatgatcagt gccagtaaaggtcgtctaggccccatggtgacctgcaccctcaaactgggaatctccatc ctaaatggaggcaatgtgcaagttcagcagaaaatgcttgattacctgaaagagaaaaga gatacagggtttttcaaaggtctctcaggactgatgcagtcttgcagtgtcctggatttg aatgcatttgagaggcagaacaaagcagaaggacttggcatggtgacagaggaaggttca atccacactgagcggggctccaaggtgctacagaatgatgagtttactaaagatctgttc cggtttttgcaacttctgtgcgaggggcacaatggagatttccagaacttcctgagaacc caaactggaaacacaaccacagtcaacattataatcagcactgtcgactatctgctccgt cttcaggaatctatcagtgacttctactggtactactctggcaaagatgtcattgatgag actggaaaagtcaacttctccaaagctttatctgtagccaagcagatattcaactcgctg actgagtatattcagggcccatgtattgggaaccagcagagtctggctcacagcagactg tgggatgcagtagtgggcttcttgcatgtatttgccaacatgcagatgaagttatctcag gatgccagtcagattgagctgttgaaggagctgatggatttacagaaggacatggttgtc atgttgctgtctctgctagagggtaatgtggtgaatggaacaattggaaagcagatggtc gacactctggtggagtcttctaacaatgtggagatgatcctcaagttcttcgatatgttc ctcaaactgaaggatctgacaacctctgacaacttcaaggagtacgaccccgattgtaaa ggcattatttcaaagaaggagttccagaagtccatggagagtcagaagcagtacacccag tctgagattgatttcctgctctcgtgtgcagagaccgatgagaacgacatgtttaattac aaggagtttgtggagcgattccatgagccggccaaagatatcggcttcaacgtggcagtg ctgctgaccaacctgtcagaacacatgccccacgactctcgacttggcaccttcttggat ctggcagagagtgtgcttaactactttgagccttacctgggtcgtattgaaatcatgggc agtgcaaagcgcatcgagagggtttactttgagatcagcgagtcaagccgtgaacagtgg gagaaaccgcaggtcaaagagtccaaacgtcagttcatctttgatgtggtcaatgagggc ggagagagcgagaagatggaaatgtttgtgaatttctgtgaggacaccatctttgagatg caactggcctcccagatctctgagccggatgctgttgagcaacctgaggaggaggaagag gaggatggacacagcatcctggaggagctggctggagaggaagaaggtgccttggagtcg gcctcggccttcaccactgcatgttgctcagtcaagaaaaagtttgcaagtgtccgccaa attatttcggttaaaaacatacgcaagcagttcaagaaaatcaggaaactgactatcaag gagattatcacaggcttcttctccttcttctggatgctcttcactggcttcttcaaggga atctacggcctcatctttggtttcttccatgtcatctggtcctccatgtttggcggtggc ctggtagagggtgccaagaacatgaaggtgacagacatccttggaaacatgcctgaccca acccaatttggtatccacggagatgtaatagaaggagagaaagcggaggccatagagtcg tcaggaagcttggataaagccatggcgccatcaggggacatagcggaggtggacgtgatg ttggagatgctgacggtacctaaaaaggaaggagggaaacacatggagcccggcctgggt gatgtttctgaactgagtacagaaatgtccactactgatcaaaaaaagaaagcttctgcc aagcccgttgaaacccctgagagtgaaccagaaaaagcagacacagagaatcgggagaag gaggataagccaaaggaggaggaggctaaggaaccagcaacagaggagaagcccaaaacc agattaggccagcctaaagaggcagcacctgccttcatgtccactatcttcgctgttctg gacatctacctgaccaagacgctgaactacctggcccgtaacttctacaacctgcgtttc ctggctctgtttgtgtgttttgccatcaatttcattctgctcttctacaaggtcactgat gaagctgatgaagaaatggacgatgaaaacgatgccgatgaccatgatgtggacacactt tttgacatggatgagtttgtgcttcaggagagcactggctacatgttgccaacgctgcgc ttcttggctgtattccacactgtgatctcgctcctctgtgtggtcggatactactgtttg aaggttcctttggtggtgttcaagagggagaaggagattgccaggaagcttgaatttgat ggtctctacattactgagcagccgtcagacgatgatatcaagggccagtgggaccgactc gtcatcaacaccccgtctttccccagcaactactgggacaagtttatcaagcgcaaggtg atcaacaaatatggtgacctgtatggagctgaacgcatcggtgagctcttaggcctggat aagagcgctctcgactttgaccccacagtggaggctgtagagaaggaggcctccctgctc tcctggctgagctccatcgacacaaagtaccacatctggaaactgggcgtggttttgact gacaattccttcctgtatctgatctggtacaccaccatgtccatttttggacacttcaac aacttcttctttgctgcccacttgctggacatcgctatgggcttcaagacccttcgcacc atcctgtcgtccgtcactcacaacgggaagcagcttgtgctgactgtgggtctgctggct gtggtggtctatctctacactgtggtggccttcaacttcttcaggaagttctacaataag agcgaggatgaagacgagcccgacatgaagtgtgacgatatgatgacgtgctatatgttc cacatgtacgtcggtgtgagggctggaggaggtattggagacgagttggaggacccagcc ggagacccctacgagctctaccgcatcctgtttgacatcaccttcttcttctttgtcatc gtcatcctgctggccatcattcagggtttgatcattgatgcctttggtgagctgagagac cagcaggagcaggtgaaggaggacatggagaccaaatgcttcatctgtggcattggcaat gactattttgatcggacgcctcacgggtttgaaacccacaccttacaggagcacaaccta gccaactacctgttcttcctgatgtacctgattaataaggacgagactgaacacacgggt caggagtcattcgtgtggaagatgtaccaggagagatgctgggacttcttccctactgga gactgcttccgtaagcaatatgaggaccagctgggttag

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