Xiphias gladius (swordfish): 120795452 Help Entry 120795452         CDS       T07311                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism xgl  Xiphias gladius (swordfish) Pathway xgl04020   Calcium signaling pathway xgl04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:xgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     120795452    04020 Calcium signaling pathway     120795452  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:xgl04040]     120795452 Ion channels [BR:xgl04040]  Voltage-gated cation channels   Ryanodine receptor    120795452 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY MIR Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 Ago_Mid Motif Other DBs NCBI-GeneID:  120795452 NCBI-ProteinID:  XP_039993328 LinkDB All DBs Position LG10 Genome browser AA seq 4875 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVACIQKENRKFCLAAEGLGNRLCYLEPTSEAKYVPP DLCICTFVLEQSLSVRALQEMLAKSGQNGEGAAQSGGHKTLLYGHAILLRHSFSSMYLAC LKTSRSQTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYL HLSISNGNIQVDASFMQTLWNVHPICSGSNIEEGYLLGGHVMRLFHGHDEVVTIPGSDQS EEQQRIVNYETGKAGAKARSLWRLEPLRISWSGSHIRWGQPFRLRHLTTGHYLALTEDRG LVLQDRERSDTVATAFCFRASKEKLEQSPKRDIEGMGVAEIKYGDSLCFITHVATGLWLS YQAPDVKSARLGPLKRRACLHTEGHMDDGLTLQRCQHEESRAARIIRNTTLLFNRFIRDL DCLGVKNRALVALPVEEVLQTLNDLITYFQLPDSELEHEERQIKLRSLKNRQNLFKQEGM LTLVSNCIDRLNVYNSAAHFGECAGFEAGAAWKDILNLLYELLAALIRGNRNNCTQFSNN LDWLVNKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNHKILDVL CSLCVCNGVAVRTNQNLICDHLLPKRDLLLQTQLVNDVQSMRPNIFLGVSEGSAQYKKWY YELMIDQVDHFVTSEPSHLRVGWANAKGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWS GRIPRAVASMNQHILTSEDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVSF SAGVKVRFLLGGRHGDFKFLPPSSYAPCYEALLPKEKMKVEPVKEYKRDVDGVRDLLGTT QFMSQASFIPTPVETSQIVMPPHLEKVRDKLAENIHELWGMNKIELGWSYGKIRDDNKRQ HPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCRVVQVNPNAEDSLKKIKLPKNYMMSN GYKPSPLDLSDIKLTPGQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSKRNPRLVP YVLLDERTKKSNRDSLREAIRTLIGYGYNIEPSDQEGGQVAERLSIDKIRFFRVERTYSV KTGKWYFEFEAVTGGDMRVGWARPGCKPDVELGTDELAFVFDGYRGHCLNMGSRLFGRCW HAGDVVGCMINMEDKSMIFTLNGEILITTKGSELCFTDFETEDGFIPVCSLGLAQVGRMN LGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPRDHNHIAVTRIDGT IDSPPCLKVTHKTFGTQNSNADMVFCRLSMPVEFHPFFKSSPVVDMNGVHEEDTLKVKHR YPLRSVRHSDESRRVDYSSITMYYYSVRVFAGQDPAGVWVGWVTPDYHYYSNNFNLTKNR TVTVTLGDERGRVHESVKRSNCYMVWGGDVTNAAHTSSRSNVDLEIGCLIDLATGLVTFT VNGKEISTSYQVEPNTKLFPAAFVRPTSPNLFQFELAKIKNAMPLSSAIFKSEHKNPVPQ CPPRLDVQTINAVLWSRMPNSFLKVETARVNERHGWVVQCVEPLQMLAVHIPEENRCVDI MELSEQKDMRKFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREG FYNVLISIHIETAKEARLMMKDEFIIPVTAETRSIRLFSDASKKHLPPGVGLSTSLKPRL NFAPPCFICTKREQHLYSPQIPLDALKEKAISMLTEAVQGGGHHIRDPVGGGVEYQFVPI LRLISTLLTMGVLGSEDVYQILLLIDPNVFRETHEEGATGATDKEGLTGAEEKAVEAGEE EAAKEAKQPMKGLLEKRLPEPVKRQMCELLHYFCDCELKHRIEAIVSFSDSFVSKLQYNQ KFRYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLTFSMGEDCPCPTDIQGELYDFHN QLQLHCGIPMEEDQDEQDTSIKGRLLMLVNKIKGQSHKAEEPTEKEQAAPSNLKELISQT MVSWAQECHIQDPELVRKMFSLLRRQYDSIGELLRAMRKTYTISAASVQDTINLLASLGQ IRSLLSVRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRILGMHETVMEVMVNVLGGDKSQ EIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAS SVMDNNGLALALEEPDLDKVVTYLAGCGLQSCLMLLAKGYPDIGWNPIEGERYLSFLRFA VFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISETPALDLPGSV QGVSSDVSADGDDEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILR SLVPTEDLVGIISIPLKMPIINKDGSVTEPDMSASFCPDHKAPMVLFLDRVYGIEDQGFL LHLLEVGFLPDLRAATSLDTEGLCTTETALAMNRYIGSAMLPLLTRCAPLFAGTEHYASL MDSTLHTIYRLSKGRSLTKAQRDAIEECLLAVCKHLRPSMLQQLLHRLVFDVPLLTEYCK MPLRLLTNHYEQNWKYYCLPSGWGSYGTASEDELLLTKKIFWGVFDSLSQRKYDPELFKM AMPCLSAIAGALPPDYVDASISTTVEKPVSVDAQGNFDPKPINTANIALPEKLEHFANKY AEHSHEKWSAEKVLLGWKYGDCVDEKAKIHPQLRTYKALTEKEKEIYRWPIRESLRSMLA MGWSIDRTKDGESMSQQRENEKLRKISQASQANGFNPSPIDTSNVVLSRELQGMVEVVAE NYHNIWAKKKKSDLGSRGGGTHPLLVPYDTLTAKEKARDREKAQDLFRFLQINAYSITRG LKDLEQDSSSMEKRFAYKFLKKLLKYVDSAQEFISHLEAMAASGKTDRSPHEQEIKFFAK VLLPLIDQYFKNHSLYFLSSPNKNLSSSGYASNKEKEMVTSLFCKLAALVRHRISLFGSD STTMVSCLHILAHTLDTRTVMKSGSEMVRVGLRTFFENAAEDLEKTFENLKLGKFTHSRS QMKGVSQNINYTTVALLPILTALFEHITQHHFGVDLLLDDVQVSCYRILTSLYALGTGKN IYVERQLPALGQCLATLAGAMPVAFLEPLLNTYNPCSVFNTKTVRERAILGIPDSVEEMC PGMPRLNGLIKDINDMAESGARYTEMPHVIEVVLPMLCNYLSYWWERGPENQPASGGSVC CTTVTSEHLSLILGNILKILNNNLGIDEASWMKRIAVYVQPIISKARADLLKSHFLPTLE KLKKKTVKVVAEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRW LKEPDADSNELFKMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDNKTKMSKSGG QDQERKHKKRRGEFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYLLKDTDDE VKDHIRQNLHLREKSEDPAVRWQLNLYKDIVMRSEGHPDPDRVVDRIQRISAAVFNLEQV EQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLLAYQRIWIETEEYSF EEELVQDLAKTQPKVEEEEEEEVRKQPDPLHQLILHFSHNALTECSSLEEDPLYIAYADM MAKSCAEGEEEEDEEGKEKTFEEKEMEKQKMLYQQARLHDRGAAEMVLQMISASKGRLGA IVTFTLKLGISILNGGNTLVQQKMLDYLKEKRDVGFFKSLSGLMFSCSVLDLNAFERQNK AEGLGMVTEEGSSSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIIS TVDYLLRLQESISDFYWYYSGKDVIDEAGQRNFSKALAVAKQVFNSLTEYIQGPCIGNQQ SLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQKDMIVMMLSLLEGNVVNG TIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSESFREYDPESKGIISKKDFQKSME NQKQYSQSEIEFLLSCAEADENDMFNYEQFVERFHEPAKDIGFNVAVLLTNLSEHMPHDA RLSTFLDLAESVLSYFEPFLGRIEIMGGAKRIERVYFEISESSRTQWEKPQVKESKRQFI FDVVNEGGESEKMELFVNFCEDTIFEMQLASQISEPDPVERPEEDEEDNQSVVENQDEGE EESMMLESSSAFTIACISLRKSLCHFRQMLTLKSMRRQYRKFRKMSVKEMVRGFFSFFWM IITGLFHFVYSLIWGFFHILWTTMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVLET EKMEASEASALAEMGQMAQGDAAEADLMAELLNIQPKKEGKHGAEPGLGDVSEVVVGDAP SIASAVKQKKAQMAAKKRATNGDYKSDSEKGDSEDGEKKDHDKAKDEAPPEHSAEEKKAP KKRLDQRKEPPEAFMASFFAGLEVYQTKMLNYLARNFYNLRFLALFVAFAINFILLFYKV TGDYSDDEDPWNNRGRAGEEEDEGALEYFVLQESTGYMAPTLRCLAILHTIISFLCVVGY YYLKVPLVVFKREKEIARKLEFAGLYITEQPSDDDIKGQWDRLVINTPSFPNNYWDKFVK RKVIKKYGDLYGAERIAELLGLDKSALDFNPTEETVAKEASLVSWLSSIDTKYHIWKMGV VFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVG LLAVVVYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIE DPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICG IGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFF PAGDCFRKQYEDQLG NT seq 14628 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggagaaggagaggatgaaatccagttcctcagaactgatgatgaagtg gtgctccagtgcgtggcctgcatccaaaaggagaatcgcaagttctgcctggctgctgag ggactgggcaaccggctgtgttacctggagcccacatctgaggcaaagtatgttcctcca gacctgtgcatctgtacctttgtgctggagcagtctctgtcggtacgggctctgcaggag atgctggccaagagcggacagaacggtgaaggggcagcgcagagcggcggacacaagact cttctgtacggacacgccatcctcctgcggcactcctttagctctatgtacctggcctgt ttgaagacatcaaggtcacagacagataagctttcctttgatgtcggcctgcaggaagac tcaacaggtgaggcctgctggtggacgatccacccagcctccaaacagagatcagaggga gagaaagtgcgcatcggcgatgacctcatcctcgtcagtgtgtcctcagagcgatacctt cacttatccatctccaatggcaatatccaggtggatgcttccttcatgcaaaccctgtgg aacgtccatcccatctgctctggtagcaacatagaggaaggctacctgctgggtggtcat gtgatgcggctgttccatggacatgacgaggtagtgaccatcccaggatcagaccaaagc gaagagcagcagaggatagtcaactatgagacgggtaaagccggtgccaaggccaggtcc ttgtggagactggagccgctaagaatcagctggagtgggagccacattcgctggggccag cctttccggctgcggcacctgaccaccggtcactacctggccctgactgaggacaggggg ttggtgctgcaagaccgggagaggtccgacactgtcgccacagccttctgcttcagagcc tctaaggagaagctggagcagagccccaagcgggacatcgagggcatgggggtggcagag attaaatacggggactcgctctgcttcatcacgcatgtggccacgggactctggctctcc tatcaggcacctgatgtcaaatctgctcgtctgggtcccctcaagagacgagcatgccta cacactgaaggtcacatggatgacgggttgaccctgcagcgctgtcaacacgaagagtcc cgcgccgcacgcatcatccgcaacaccacactactctttaaccgattcatcagagacctg gactgtctgggtgttaagaatagggcactggtcgcactgcctgtcgaggaggtgctccaa actctcaatgacctcatcacctatttccagctccctgactctgagctggagcatgaagag aggcagatcaagctgcgctcactcaagaaccgacagaacctattcaaacaggagggcatg ctgactctggtgtccaactgtatcgaccgtctgaacgtgtacaacagtgcggcccacttt ggggagtgcgccgggttcgaggccggagcagcctggaaagacattctgaacctgctgtac gagctgctggcggcgttaatccgagggaacaggaacaactgcacccagttctccaacaac ttggactggctggtgaacaagctggagagactggagtcttcttcaggcatcctggaagtt ctgcactgcatcctaattgagagccccgaggccctcaacatcatccagagaggacacatc aagtcgatcatatcactgctctacaagcacggacgcaaccacaagattctggacgtgctc tgctcgctgtgtgtgtgtaacggcgtagctgttagaaccaatcagaaccttatctgtgat cacttgctgcccaagagagatctgctgctgcaaacccagctggtcaatgatgtccagagt atgagaccaaacatcttcctgggtgtgagtgagggctcagctcagtataagaagtggtac tatgagctgatgatcgaccaggtggaccactttgtgaccagtgagccctcccacctgaga gtgggctgggccaatgctaaaggatatgctccctaccctggaggaggagagggctggggg gggaatggcgttggagatgacctctactcgtatggttttgatggactccacctctggtca ggtcgtatcccgcgggcggttgcgtccatgaaccagcacatcctgacctcagaggatgtg gttagctgttgtctggacctgggagcacccagcatctctttcaggatcaacgggcagccc gtccagggcatgtttgaaaatttcaacacagacggcctcttcttccctgtcgtcagcttc tctgcaggggtcaaggtgcgtttcctgttgggtggtcgacatggcgactttaaattcctg cctccatcaagttatgctccctgttatgaggctctgctgccgaaagagaagatgaaggtg gagccagtgaaagagtacaagagggatgtggacggagtcagagatctgctgggcaccacc cagttcatgtcacaggcctccttcatccccacacccgttgaaaccagccagattgtgatg ccacctcatttggagaaggttcgggacaagctggctgagaacattcacgaattgtggggc atgaataagattgagctgggctggtcatatggcaagataagggatgataataagcggcag catccatgcctcgtggatttctccaagctaccagaaacagaaaagaactacaatctacag atgtcaacagaaactctgaagaccctgctggcattggggtgtcgtgtggttcaggtgaat ccaaatgctgaggactccctcaaaaagataaaactccctaagaactacatgatgtctaat ggatataagccatcccctctggatctgtctgacataaaactgactccgggtcaggagctg ctggtggacaaactggcagagaatgcacacaatgtgtgggccaaggaccgtatcaaacag ggatggacctacggcattcagcaggatctgaagagtaagcgtaaccctcgcctggttccc tatgttctgctcgatgagcgcaccaagaagtcgaatagggacagcctgcgggaggctatc cgcactctgattggctatggatacaacattgagccctcggaccaggaaggcggacaagtg gctgagcggctcagcatcgataagatccgcttcttcagagtagagaggacatactcggtg aagacagggaagtggtactttgaatttgaagctgtgacgggaggagacatgagagtgggt tgggccagacctggatgtaagccagatgtggaacttggaacagatgagcttgctttcgtc tttgatgggtacaggggccattgtctgaacatgggcagccgtttgttcgggcggtgctgg catgctggggacgtggtgggctgtatgatcaacatggaggacaagtccatgatctttacc cttaatggagagatcctcatcaccaccaagggctctgaactctgcttcactgactttgaa actgaggatgggttcattccagtgtgtagtcttgggctggctcaggtgggtcgtatgaat ctgggcaaagatgctagcaccttcaagtactacaccatgtgtggccttcaggaagggttt gaacccttcgctgtcaacatgaacagagaggtcaccatgtggttcagcaagcgtctgcct acttttgtcaatgtgccgagggaccataatcacatcgcagtaaccaggattgatggcacc atcgacagccccccgtgtcttaaagtcacccacaagacgtttggcacccagaacagtaat gctgacatggtgttttgtcgtctcagcatgcctgtagagttccaccccttcttcaagtcc agtccagttgtagacatgaatggagtgcatgaggaagatacccttaaagtcaaacacagg tatccattgaggtctgtgaggcacagtgatgaaagcagacgagtggactacagcagcatc actatgtactattattcagtgagggtctttgctggtcaggaccctgccggtgtgtgggtt ggatgggtaacccctgactaccattactatagcaacaatttcaacctcacaaaaaaccga acggtgactgtaaccctgggtgacgagcgaggacgagtccatgagagtgtgaagaggagt aactgctacatggtgtggggtggggatgtgaccaatgctgctcacacctccagtcgcagc aacgtggacttggagattggctgtctgatagacctggcaaccggcctggtaacattcact gtcaatggcaaagagatatccacatcctaccaggtggaaccgaacaccaagctcttccct gctgcgtttgtgcgacccaccagcccgaacctcttccagtttgagctggctaaaataaag aatgccatgcctctgtcatcagccatctttaagagtgaacataagaatccggtgccacag tgtccgccccgtctagatgtccagaccatcaatgcagtgctttggagccgcatgcccaac tcctttctgaaggtggaaacagccagggtcaatgagagacatggctgggtggtccagtgt gtggagcccctgcagatgttggctgtacacatacctgaggagaacaggtgtgtcgacatc atggagctgtctgagcagaaggacatgaggaagttccactaccacaccctgaagctctac tgtgccctctgtgctctgggaaacacccgcgtggcccatgccctctgcagccacctggac cagtctcagctcttatacaccatcgacaatcagtacctgtcaggcatgttgcgtgagggc ttctacaatgtcctgatcagcatccacattgagactgccaaagaggcacgactcatgatg aaagacgagttcatcatccccgtcacggctgagacgcgctccattcgtctcttttctgat gcttccaaaaagcacctcccgccgggggtggggcttagcacctcgctcaaaccgcgcctc aactttgccccgccctgtttcatctgcaccaaacgggagcagcatctgtatagtccccaa atcccactggatgcactgaaggagaaagcaatttcaatgttgacagaggctgttcaaggt ggagggcaccacatccgagaccctgtgggaggaggtgtggagtaccagtttgtgccaatc ctgaggctcattagcaccttgctgactatgggcgtattagggagtgaggatgtttatcag atcctactgctcattgacccaaatgtgttcagagagacacatgaggagggagccacgggg gccacagacaaagagggacttacaggggcagaggagaaggcggtggaagctggagaagag gaggcagccaaggaggctaagcagccaatgaaaggactgctggagaagaggctgcccgag cctgtcaaacgacagatgtgcgagctgcttcactatttctgcgactgtgagctgaagcac cgcatcgaggccatcgtgtccttttctgacagcttcgtgtcaaagctgcagtacaaccag aagttccgctacaacgagctgatgctggccctcaacatgtcagccgctgtaactgcaaag aagaccaaagagttcagatcacctccgcaagaacagatcaacatgctgctgaccttcagt atgggagaggactgtccgtgtccaacggacatccagggtgaactctacgattttcacaac cagctgcagctccactgtggaatccctatggaggaagaccaagacgagcaggatacatct attaaaggtcgtctcctaatgctggtaaacaagatcaaaggccagtcccacaaagcagaa gagcccacagagaaggagcaagccgcaccatccaatctgaaggaactgatctctcagacg atggtaagctgggcccaggagtgtcacatccaggacccagagctcgtccgtaagatgttc agcctgctgaggaggcagtatgacagcatcggggaactgctccgggccatgaggaagact tacaccatcagtgccgcctcggtgcaggacaccatcaacctccttgcctcactgggtcag atcagatctctgctgtctgtccgcatggggaaagaggaggagaagctcatgattgatgga cttggcgacatcatgaacaacaaggtgttctaccagcacccgaacctaatgagaatactg ggcatgcacgagactgtcatggaggtcatggtcaatgtgctcggaggagacaaatcccag gaaattgccttcccaaagatggtggccagctgttgtcgcttcctgtgctacttctgccgg atcagccgtcagaaccagaaagccatgtttgaccaccttagttacctgctggagaacagc agcgtgggtctagcttcaccagctatgaggggttccactcctctagatgtggctgcttca tcagtgatggacaacaacggcctggctctggcactggaagaacccgatctggacaaggta gtcacctacctggcaggatgtggtctccagagttgtctaatgcttctggctaaaggctat ccagacattggctggaaccccattgaaggagaacgttacctttccttcttgcggtttgcc gtcttcgtcaacggtgagagtgtggaggaaaactccagtgtcgtggtcaagctgctcatc cgtcgtccggagtgtttcggacctgccctgaggggagagggagggaacggcctgctggcc gcaatgaaggaagctattaagatctctgagacacctgctttggacctgccgggctctgtc cagggagtcagctctgacgtgtctgcggatggtgatgacgaggaagaggtggttcacatg ggcaatgccattatgtccttctactctgcgctcatagaccttttgggacgttgcgcccca gagatgcatctcataaacaaggggaaaggtgaagctctgcgtattcgtgccatcttgcgc tctctggtgcctaccgaggaccttgtggggattatcagcataccactcaaaatgcccatc attaacaaagatgggtcagtgacagagccggacatgtcagccagcttttgtccagaccac aaggcccccatggtcttgtttctggacagggtgtatggtattgaggaccagggctttctg cttcacctgcttgaagtcggctttctccctgacctgagggctgctacctctctggacacg gagggtctctgtaccactgagacagccctggccatgaatcgctacatcggctcagccatg ctacccctcctcacccgctgcgcccctctctttgcgggcaccgagcattacgccagcctc atggactccactcttcacaccatctaccgcctttccaagggccgttcactcaccaaggcc cagagagatgccatagaggagtgtctgctggccgtctgcaaacaccttcgtccgtctatg ctgcagcagctcctgcaccgactcgtctttgatgtgcccttgctgactgaatactgcaag atgcctctcaggctgctaaccaaccactatgagcagaactggaagtactactgcctcccg tcgggctgggggagctatggcacggcatctgaggatgagctactgctcaccaagaagatc ttctggggagtgtttgattctctgtcccagaggaaatatgacccagagctattcaagatg gccatgccttgcctcagtgccatagctggagctttgccgccagactatgtggatgcctcc attagtaccactgtggaaaagcctgtttctgtcgacgctcagggcaactttgaccccaaa cccatcaatactgctaacattgctcttccagagaagcttgagcactttgccaacaaatat gccgagcattcccatgagaaatggtctgcagagaaggtgctgctgggatggaaatacgga gactgtgtggatgagaaggccaagattcaccctcagctcaggacctacaaagccctaaca gagaaggagaaggagatttacagatggccaattagagagtccctgaggagtatgttggca atgggctggagcatcgacaggaccaaggatggagagagcatgtctcaacagagagagaat gagaaattgagaaagatatctcaggcctcacaggcaaatgggttcaatccaagcccgata gacacaagcaacgtggttctatccagggaactgcaggggatggtggaggtagtggctgaa aattaccataacatctgggccaagaagaaaaaaagtgacctgggaagcagaggtggggga acccaccctctgttggtgccctacgacacgctgacagccaaggagaaggcccgtgatcga gagaaggcccaggacctttttcgcttcctgcaaatcaatgcctatagcatcacaagaggt ttgaaggacttggagcaggattcttcttccatggagaagaggtttgcctataagttcctc aagaagctgctcaagtatgttgactcagctcaggaattcatctcccatctagaggccatg gctgcgagtggaaaaacagacaggtcccctcatgaacaggaaatcaagttttttgccaaa gttcttctccctctcatcgaccagtacttcaagaaccactctctatacttcctctcctcc cccaataagaacctgagcagcagcggttacgcctccaacaaggagaaggagatggtcacc agcctgttttgtaaactggcagctcttgtcagacataggatttcactctttgggagtgac tccaccaccatggtgagctgtctgcatatcctggcacacactctggacaccaggacggtg atgaagtcgggctcagagatggtgcgggtggggctgaggacattctttgagaacgccgca gaggacctggagaagacgttcgagaacctcaagctggggaagttcactcactcccgctcg cagatgaaaggggtgtcgcagaatatcaactacaccactgtggctctgctccccatctta accgctctgtttgaacacatcactcagcaccactttggagtcgacctgctgttggatgat gtccaagtctcctgctatcgaatcctgaccagcctctatgcactgggcactggaaaaaac atctacgtagaaagacagctgccagctcttggtcagtgtctggctaccctggctggggcc atgcctgtggccttcttggagccattgctcaacacgtacaacccctgctcggtttttaat accaagactgtccgggaacgagccatcctaggcataccagactcagtcgaggagatgtgt cccgggatgccgcggctgaacggcctgattaaggacatcaatgacatggctgagtctggg gcacggtacacagagatgcctcatgttatcgaggtggtgctgcccatgctgtgtaactat ctgtcctattggtgggagagggggcctgagaaccagccagccagcgggggcagcgtctgc tgcaccaccgtcacctcagagcacctcagcctcattctcggcaacatcctcaagatcctc aacaacaacctgggcatcgatgaggcctcgtggatgaagaggattgcagtgtacgtgcaa cccatcatcagcaaggctcgtgcagacctgctgaagagccacttcctgcccacactggag aagctaaagaagaagacggtgaaggtggtggctgaggaggagctgctgaaggcggacagc aagggagacacccaggaggccgagctgctcatcctggacgagtttgctgtactctgcaga gacttgtatgccttttaccccatgcttatccgctacgtggacaacaacaggtccaggtgg ctgaaggaaccagatgctgactccaatgagctcttcaaaatggtcgcagagatttttatc ctctggtgcaagtcccataatttcaaaagagaggagcagaactttgtggtccagaacgaa attaacaacctttcctttttgactggagataataaaaccaagatgtcaaagtctggagga caggaccaggagaggaaacacaagaaaaggcgtggcgagttttactccatccagacctcg ctgattgtggctgctttgaagaagatgctgccaatcggtctcaacatgtgtaccccaggg gatcaggagctcatatctctagccaagacccggtacctcctgaaagatacggatgacgag gtcaaagaccacattcggcagaatctgcatcttcgagaaaagtcagaggaccctgcagtg aggtggcagctaaacctgtacaaggacatagtgatgaggagcgaggggcatccagaccct gacagggtggtggaccgtatccagaggatctccgctgcggtcttcaacctggagcaggtc gagcagccactgagatccaaaaaatgtgtttggcagaagttgctgtccaagcagaggaag agagcggttgtagcctgcttccgcatggctccgctttataatctaccaaggcatcgctct attaacctcttcctcctggcctatcagagaatatggatagaaacagaggagtactctttt gaggaggagctagtacaggatcttgcaaaaacgcagcccaaagtggaggaagaggaagag gaggaggtcagaaaacaaccagacccgcttcaccagctcattctgcatttcagccacaac gctctgactgagtgcagttctttggaagaggatcccttgtacattgcatatgcagatatg atggcaaagagttgtgctgaaggtgaagaagaggaagatgaggaaggaaaagagaaaaca tttgaggaaaaggaaatggagaagcaaaagatgctgtatcagcaagccagacttcacgat cgaggggctgcagagatggttctccagatgatcagtgccagcaaaggtcgactaggtgct attgtgacgttcaccctcaaactgggcatctccattctgaatgggggtaacacactggtc cagcagaaaatgctggactatctgaaggaaaaaagagatgttggctttttcaaaagttta tctggactgatgttttcttgcagtgtcctggacttgaatgcttttgaaaggcaaaacaaa gctgaaggtctggggatggttactgaagaaggatcaagttccaaggtactgcagaatgat gagttcactaaggatctttttaggtttctgcagcttctctgtgaaggccacaacaatgat tttcagaacttcctgaggactcagacagggaacacaactacagttaacatcatcattagt actgtagactacctactaagactccaggaatccatcagcgatttctactggtactactct ggtaaggatgtcattgatgaggccggtcaaaggaacttctccaaagccctggcagtggcc aagcaggtcttcaactctttaactgagtatatacagggtccatgcattgggaaccagcag agtctggctcacagcaggctatgggatgctgtggtgggctttctgcatgtttttgccaac atgcagatgaaactatcccaggactccagtcagattgaattattgaaggagctgctggac ctacagaaggatatgatcgttatgatgctctctcttctcgaaggtaatgttgtcaatggt accattggcaaacaaatggtggacactttagtggaatcttctagcaacgtggagatgatc ctaaaattttttgacatgttcctcaagttgaaggacttaaccacctcagagagcttcagg gagtacgaccctgagagcaaagggatcatctcaaagaaggatttccagaagtccatggag aaccagaaacagtactcccagtctgagattgaatttcttctctcttgtgccgaggctgat gagaacgacatgttcaactacgagcagtttgtggagagatttcacgaacctgccaaggac attggcttcaatgtagctgtgttgctaaccaatctctctgagcatatgcctcatgatgct cgcctctcaacgttcctcgacctggctgagagtgttctcagctactttgagccctttttg ggtcgtattgagatcatgggtggagcgaagcgcatcgagagagtctacttcgagatcagt gagtcgagtcgtacccagtgggaaaagcctcaggtgaaggagtcaaagcggcagtttatc tttgatgttgtcaatgaaggtggagagagtgagaagatggaactgtttgtcaacttctgt gaggacaccatctttgagatgcaactggcttctcaaatttccgagccagacccggtggag cgcccggaggaagacgaagaagacaaccagagtgtggtggagaaccaggacgagggagag gaggaaagcatgatgttggagtcttcctctgccttcacaatcgcctgcatctccttgaga aaaagcctctgccactttcgccaaatgctaaccctcaagagcatgaggcggcagtacagg aaattcaggaagatgagtgtgaaggagatggtgagaggcttcttctctttcttctggatg atcatcacaggactcttccactttgtctacagccttatttggggtttcttccatatcttg tggaccactatgtttggtggtggccttgttgaaggggctaagaatatgaaggtgacagat attttgggaaacatgccagatcccactcagtttggcatccatggagatgtgttagagacg gagaagatggaggcgagtgaagcgtcagcgttggcagagatgggtcagatggctcagggg gacgcagcagaggcagacctgatggctgagttgctgaacatacagcccaagaaggaggga aagcatggggctgagccggggttgggggatgtgtctgaggtggtggtgggggatgctcca tctattgccagtgccgtcaagcagaagaaggcacagatggctgcaaagaagagggctaca aatggagactacaagtctgattcagaaaaaggagattcagaagacggtgagaagaaggac cacgacaaagctaaagacgaagcccccccagaacactctgcggaggagaagaaagccccc aagaagcggctcgaccagaggaaagaaccaccagaggccttcatggccagcttcttcgct ggcttggaagtctaccagactaaaatgctgaactaccttgccagaaacttctacaacctc cgctttctggcactttttgtcgcctttgccatcaacttcattctgctcttctacaaagta accggtgattactcagatgatgaagatccctggaataatcgaggtagagctggggaggag gaagatgaaggggcgcttgagtacttcgtcctgcaggagagcacaggctacatggcgcca acacttcgctgtctagcaatactacacactatcatatctttcctgtgtgtagtaggatac tactaccttaaggtgcctctggtggtgttcaaacgtgagaaggagatagcgaggaagttg gagtttgccggcctctacatcactgagcagccgtctgatgatgacatcaaaggacagtgg gaccgactggtcatcaatactccttccttcccgaacaactactgggataaatttgtcaaa cgcaaagtgatcaaaaagtacggagacctgtatggggcagagaggatagcggagctgctg ggattggacaaaagtgccctggatttcaaccctacagaggaaactgtcgccaaggaggct tcactggtgtcatggttgagctcaatcgatacaaagtaccacatctggaaaatgggagtg gtgtttacagacaattctttcttgtatctagtatggtacaccaccatgtccattctgggc cactacaacaacttcttcttcgccgcccatctcctggacatcgccatgggcttcaagacc cttcgcaccatcctctcgtctgtcacacacaatggcaaacagctggtgttgaccgtaggc ctgctggcagtcgtggtctatctctacactgtggtggccttcaacttcttcaggaagttt tacaacaagagcgaggacgatgatgagccggacatgaagtgcgatgacatgatgacgtgc tacttgttccacatgtacgttggggtgagagcaggagggggcatcggggatgagatcgag gacccggctggtgacccttatgagctctaccgcatcctttttgacattaccttcttcttc tttgtcatcgtcatcctcctggccatcatccagggtttgatcattgatgcgtttggagag ctgagagaccagcaggaacaagtcaaagaggacatggagaccaaatgcttcatttgtggg atcggtaatgattatttcgacacaacacctcacggctttgagactcacaccttacaagag cacaatttggccaactacctgtttttcctgatgtatcttatcaacaaggatgagacagag cacactggccaggagtcatatgtgtggaagatgtaccaggagcgatgctgggatttcttc ccagctggagattgcttccgcaaacagtacgaagatcagcttggatag

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