KEGG   Xiphophorus hellerii (green swordtail): 116721571
Entry
116721571         CDS       T07363                                 
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
xhe  Xiphophorus hellerii (green swordtail)
Pathway
xhe00562  Inositol phosphate metabolism
xhe01100  Metabolic pathways
xhe04012  ErbB signaling pathway
xhe04068  FoxO signaling pathway
xhe04070  Phosphatidylinositol signaling system
xhe04081  Hormone signaling
xhe04140  Autophagy - animal
xhe04145  Phagocytosis
xhe04150  mTOR signaling pathway
xhe04210  Apoptosis
xhe04218  Cellular senescence
xhe04370  VEGF signaling pathway
xhe04510  Focal adhesion
xhe04517  IgSF CAM signaling
xhe04518  Integrin signaling
xhe04620  Toll-like receptor signaling pathway
xhe04625  C-type lectin receptor signaling pathway
xhe04810  Regulation of actin cytoskeleton
xhe04910  Insulin signaling pathway
xhe04914  Progesterone-mediated oocyte maturation
xhe05100  Bacterial invasion of epithelial cells
xhe05132  Salmonella infection
xhe05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:xhe00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    116721571
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    116721571
   04370 VEGF signaling pathway
    116721571
   04068 FoxO signaling pathway
    116721571
   04070 Phosphatidylinositol signaling system
    116721571
   04150 mTOR signaling pathway
    116721571
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    116721571
   04517 IgSF CAM signaling
    116721571
   04518 Integrin signaling
    116721571
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    116721571
   04140 Autophagy - animal
    116721571
  09143 Cell growth and death
   04210 Apoptosis
    116721571
   04218 Cellular senescence
    116721571
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    116721571
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116721571
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    116721571
   04625 C-type lectin receptor signaling pathway
    116721571
  09152 Endocrine system
   04910 Insulin signaling pathway
    116721571
   04914 Progesterone-mediated oocyte maturation
    116721571
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    116721571
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116721571
   05100 Bacterial invasion of epithelial cells
    116721571
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:xhe04131]
    116721571
Enzymes [BR:xhe01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     116721571
Membrane trafficking [BR:xhe04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    116721571
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_C2 PI3K_p85B DUF2321 ABC1 Ribosomal_S15
Other DBs
NCBI-GeneID: 116721571
NCBI-ProteinID: XP_032421302
LinkDB
Position
6:4057428..4078685
AA seq 1068 aa
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGSHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMSKESLYSQLPME
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYVTEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSMIEDHANWNISRELGFNYSHPGLSNRLARDKPLTESDNEQLRQVCNRDPL
SEITEQEKDFLWSHRHYCINIPDILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMKRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctccgcggccctcttccggagaactatgggggatgcacttgatgccccccagcatc
ctagtggattgcctgctgccaaacggcatgatcctcacgttggagtgcctccgggaggct
acgctcattacggtcaagcacgagctcttcaaggaagccaggaagtaccccctctaccat
ctgctgcaggaggagagctcctacatcttcgtcagcgtcacgcaggaggccgagcgcgag
gagttttacgacgagaccaggaggctgtgcgatctcaggctcttccaggctttcctcaaa
gttatcgagccagtgggcaacagagaggagaaaatcctcaacagagaaataggcttcgcc
atcggaatgcccatatgcgagtttgatttggtgaaggactccgaagtgcaggacttcaga
aggaacattttaaatgtttgcaaagaagccgtggacctcagagacagcaacggctcccac
agcagagcgctgtacgtctacccgcctaacgtggaatcgtccgcagagcttcccaggcat
atctacaataaactagataaaggccagattatcgtggtgatctgggtcatcgtttctccc
agcaacgacaagcagaagtacaccctgaagatcaaccacgactgcgtgcccgagcaggtg
atcgccgaagccatccggaagaagacgcgcagcatgctgctcactcaggagcagctgaag
atgtgcgtccaggagtaccaggggaagtacatcctcaaagtctgcggctgcgacgagtac
ttactggagaaataccccctgagtcagtacaagtacatccgcagctgcatcatgctggga
aggatgcccaacctgatgctgatgtccaaagagagcctgtattcccagctgcccatggag
aacttcaccatgccgtcgtacgccaggcggatctccacggcgacgccctacatgaacggc
gagacggccaccaagtgtctctggacaatcaacgggacgctgaggatcaggatcctctgc
gctacctatgtcaatgtaaacatcagagacatagacaagatctacgtcaggactgggatc
taccatggtggggagcagctgtgtgacaacgtcaacactcagcgcgttccctgctctaat
cccaggtggaacgagtggctgacctacgacatgtacgtcacagaaatccccagagccgct
cgactctgcctctccatctgctccgtcaaaggaaggaagggagctaaagaggaacattgt
cccctggcctggggcaacatcaacctgtttgactacacacacacgctggtagcggggaaa
atggctctcaacctgtggcctgtcccacatggcctggaggatctgctcaaccccatcggt
gtcacaggctccaaccccaacaaggaaaccccttgcttggagctggagttcgaccacttc
agctgcccagtcaagttccccgacatgagcatgatcgaggatcacgccaactggaacatt
tcccgggagctcggctttaattactcacaccccggcttgagcaacaggctggcacgagac
aaacccctgactgagagcgataatgagcagctgcgccaagtgtgtaaccgggaccctctg
tctgagatcactgagcaggagaaggactttctgtggagtcacagacattactgcatcaac
atcccagatatccttcccaagatcctcctggctgtgaagtggaactccagagacgaggtc
gcgcagatgtattgccttctcaaagactggcctgccattaagccagaacaagccatggag
ttgctggactgcaacttccccgaccccatgatccgagagttcgccgtgaagtgccttgag
aaatacctaaccgacgacaaactgtcgcagtacctcatccagctggtccaggttctgaag
tatgagcagtacctggacaacccgctcgcacgcttcctgctgaaaaaggctttgaccaat
cagaggataggacacttcttcttctggcatttaaaatcagagatgcacaacaagacggtg
agccagcgcttcggccttctgctggagtcgtactgccgggcgtgcggcatgtatctgaag
cacctgagccggcaggtggaggccatggagaagctcatcaatctcaccgacctgctcaag
caggagaaaaaagacgaggcgcagaaggtccaaatgaagtttctggtcgagcagatgaag
aggcctgactacatggatgcactacagagctttacctctccgctcaacccggcacatcag
ctgggaaacctccgcctggaggaatgtcggatgatgtcatcggcaaagcgacctctctgg
ctgaactgggaaaacccggacatgatgtccgaactcctcttccagaacaacgaaatcatc
ttcaaaaatggagacgatctgaggcaggacatgctgacgctgcagatcattaggataatg
gagaacatctggcagaaccagggccttgatctcaggatgctgccgtacggctgcctgtct
atcggcgactgcgtggggttgatcgaagtggtgaggaactctcacaccatcatgcagatc
cagtgcaaaggaggcctgaagggggcgttgcagttcaacagccacgctctgcaccagtgg
ctcaaggataagaacaagggggaaatgtacgaccaggccatcgatctgttcacccggtcg
tgcgccggctactgcgtggccaccttcatcctcggcattggagacagacacaacagcaac
atcatggtgaaagatgacggacagctgttccacatcgacttcggccatttcctcgaccac
aaaaagaagaagttcgggtacaagagagagcgggtcccgtttgttctcacgcaggacttc
ttgatcgtcatcagcaaaggaacgcaagagtgtacaaaaaccagagagttcgaaagattc
caggagatgtgctacaaggcgtacctggccatccggcagcacgccaacctcttcatcaac
ctgttctccatgatgctgggctcgggcatgccagagctgcagtcgttcgacgacatcgcc
tacatcaggaagaccctggccctggacaagtccgagcaggaggcgctcgactacttcatg
aagcagatgaacgacgcccatcacggcggctggaccaccaagatggactggatcttccac
accatccgccagcacgccatgaactga

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