Xenopus laevis (African clawed frog): 108702492
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Entry
108702492 CDS
T01010
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla04010
MAPK signaling pathway
xla04012
ErbB signaling pathway
xla04020
Calcium signaling pathway
xla04510
Focal adhesion
xla04520
Adherens junction
xla04530
Tight junction
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108702492
04012 ErbB signaling pathway
108702492
04020 Calcium signaling pathway
108702492
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
108702492
04520 Adherens junction
108702492
04530 Tight junction
108702492
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xla01001
]
108702492
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
xla04147
]
108702492
04090 CD molecules [BR:
xla04090
]
108702492
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
108702492
Protein kinases [BR:
xla01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
108702492
Exosome [BR:
xla04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
108702492
CD molecules [BR:
xla04090
]
Proteins
108702492
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
ABC1
DOR
HAUS-augmin3
Kinase-like
V_ATPase_I
ADIP
TPR_MLP1_2
Motif
Other DBs
NCBI-GeneID:
108702492
NCBI-ProteinID:
XP_018093465
UniProt:
A0A974BSL2
A0A1L8EKP1
LinkDB
All DBs
Position
9_10S:complement(1962223..1993418)
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AA seq
1290 aa
AA seq
DB search
MEPRRSCRSGLLLLLLIVQTRGQEVCTGTDMKLLHPFSQRNHYETLHTIYRDCQVIQGNL
EITYLKEDDDVSFLQNIKEVHGYVLIAHNLLSYLPLENLRIIRGTQLYQERYALAVLSNS
EAGGTAGLRELRMRKLTEILKGGVIIQNNTQLCFQETVLWMDILSQSNSQRKEVVLDSSH
RQCPLCSPACGSLPSGRSGLCWGVGQEYCQTLTSTICDSGCQRCKGNHSTHCCHEQCAAG
CTGPKNSDCLACLLFNHSGVCGTHCPPLSTYNPETYESVHNEGGRYTFGASCVTSCPYNY
LATEVGSCTLFCPKDNKEVIVGNMQKCEKCDKQCSKVCYGLGRDFLRTTQAINASIIHHF
QGCTKIFGSLAFLAESFKPDPNKPGSVLTAQNLEVFKTLEEITGYIYIESWPEELNSLSV
FENLRVIRGRMLQNGAYSLVLRNLSISSLGLRSLTEISSGLAQIEGNPNLCFLESAPWSD
LFKTQRQTIVKTLNKPQEVCDQEGQKCFSRCAGEKCWGPGPSQCVRCNGFLRGHDCIESC
NVLDGDPREHVNGSQCVPCHSQCYQQNGTQTCSGPEADQCMACAHYMDGEDCVEQCPKGS
SFVPIWKYPDKDGICQLCLVNCSHSCNQLDERGCPILPDNSQVYMAASIIISILIVITIS
TAIVLSIRRRKQLRRKHTTRRLLQEELVEPLTPSGAVPNQAQMRILKETELKKMMILGSG
AFGTVYKGIWIPDGENIKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVCRLLGIC
LTSTVQLVTQLMPYGCLLDYVRENKDRIGSRDLLNWCVQIAKGMTYLEEVRLVHRDLAAR
NVLVKSPTHVKITDFGLARLLDVDETEYHADGGKVPIKWMALESILHRRFTHQSDVWSYG
VTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPVCTIDVYMIMVKCWMIDSECRPKF
RELVHELSRMARDPSRFVVIENEEIMAQASPLTTQFYSALLQEVGMDDLVDAEEYLVPHR
GFFPSEDVTAEHCSRISSMQSATEMQPCQPFLQEVLPSGAALARTLSEKSGGSGSDAFSE
GDYVFEPPLTGESGSPHGYTDDPVHLGEDETDSCFFEADCVSPSIPPHPLAEYVNQKEGE
RNHSPIKSLRTSVSTLERQKPTLERQKSTLERQKSTLERQKSTLERQKSTLDRQKSTLER
QKGQQCKNGLRSPPPLSALDNPDFLPPPRLILPNGFPQAFDNPYYWNHELNIAKADGDPQ
AHNGFTTPTAENPEYLGLDDTMIRPRDITV
NT seq
3873 nt
NT seq
+upstream
nt +downstream
nt
atggagccgagaaggagttgcaggtcggggctcctgttgctgctgctgatcgttcagact
cggggacaggaagtttgtactggaaccgatatgaaactacttcatcccttcagccagagg
aatcactatgagaccctccatactatctaccgggactgccaagtcatccaagggaattta
gagataacctacttaaaagaagatgatgatgtatcctttctgcagaatatcaaagaagtc
catggctatgtcctaattgctcataacttgttgagttatctgcccttggagaatttacgg
atcatccgcggcacgcaactgtaccaagaacgttacgcgctcgccgtgctgtccaattca
gaggccggagggacggccggcctgcgggagctgcgcatgaggaagctaacggaaatccta
aagggtggcgtgatcatacagaacaacacacagctatgtttccaggagaccgttttgtgg
atggacatcctgagccaaagcaacagccagagaaaagaggtggtcctagactccagccac
cggcagtgcccgctctgctctcctgcatgcggctcccttccctcgggcagatctggattg
tgttggggagtgggccaggagtattgtcagaccttaaccagcactatctgtgacagcggc
tgccagagatgtaaagggaaccattcaactcactgctgtcatgaacagtgtgccgccggc
tgtactggacccaagaactcagactgcctggcctgccttctctttaaccacagcggagtg
tgtgggacgcactgcccccctctctcaacctacaacccagagacctacgagtctgtacac
aacgagggtggccggtacacgttcggcgccagctgcgtcacttcttgcccctataactac
cttgccaccgaggttggctcttgcacactcttttgccctaaggataacaaggaggtgatt
gtgggaaatatgcaaaaatgtgagaaatgtgacaagcagtgcagcaaagtgtgttatggg
cttggaagagatttcttgagaacaacacaagccattaatgcttctatcatccatcatttc
caaggctgcactaagatctttgggagtctggcattccttgccgagtccttcaaaccagat
cccaacaaacccggctcagtcctcactgcacagaaccttgaggtcttcaagacccttgaa
gaaatcacaggatacatctatattgagtcctggccagaagaacttaacagtctcagtgtc
tttgagaacctgcgtgtgattcgcggacgaatgctacagaacggggcatattcattggtc
ctgaggaacctttccatctcatctcttggcttgcgctccttgacggaaatcagcagtggg
ctggcacagatagaggggaaccccaacctgtgcttcttggaaagtgccccatggtcggat
ctcttcaaaacccaaagacaaactatagtaaagacactcaacaaaccccaagaagtgtgc
gaccaagaagggcagaagtgcttcagtcgctgcgctggagagaaatgctggggtcctggc
ccttcccagtgcgttcggtgcaatggattcctgagaggccatgattgcattgagtcttgc
aatgttttggatggagacccaagagagcatgttaatggaagtcagtgtgtgccttgccac
tctcagtgctatcagcagaatggaactcagacatgctctggcccggaggctgaccagtgt
atggcgtgtgctcactatatggacggagaagactgtgtggagcagtgccctaagggaagt
tcctttgttcccatttggaaatacccagacaaggatgggatctgccagctgtgccttgtc
aactgctcacactcgtgcaatcagttggatgaaaggggctgcccaattttaccggacaac
agccaagtgtacatggcagcttcaattatcattagcatattaatcgtgatcaccatatca
acggccatcgtgttgtcgatccggcgcagaaagcagctgaggaggaagcacaccacacgt
cgccttttacaagaagagctcgtggaacctctgactccaagtggagctgtccccaaccaa
gcccagatgaggatccttaaggagacagaacttaagaagatgatgatcttgggatctggg
gcatttggtactgtatacaagggtatttggattccagatggtgaaaatatcaaaataccg
gttgccattaaagttttgagggagaacacatcacctaaagccaacaaggagatccttgat
gaagcatatgtgatggcaggggtgggcagcccttatgtgtgtcgcctgcttgggatctgc
ctcacatctaccgtacagcttgtcacccagctcatgccatacggctgcttactggactac
gtgagggagaacaaagaccgcattggctccagagatctcctcaactggtgtgtgcagata
gcaaaggggatgacatacctggaggaggtgcgtttggtgcacagagacttagctgcaagg
aacgtcttggtgaagagcccaacgcatgtgaagatcacagactttggcctggcccgactg
ttagatgtggacgagactgagtaccatgctgatggtggaaaggtccccatcaaatggatg
gctttagagtccattttgcaccgaagattcacccaccagagtgatgtgtggagctacggt
gtaaccgtttgggagctcatgacctttggtgcaaaaccctatgatggaatcccagccaga
gaaatcccagaccttttggaaaaaggagagaggctccctcagccaccagtttgcaccata
gacgtttatatgatcatggtgaagtgctggatgatagactccgaatgccgacccaaattt
cgggaacttgtccatgaattatctcgtatggcacgcgatccatcacgttttgtggtcatt
gagaatgaagagatcatggcccaggcgagcccactgaccacccagttttacagtgctctg
cttcaagaggttgggatggatgacctggtagatgcagaggaatatctggtgccccacagg
ggatttttcccatcagaagatgttactgcagagcattgcagtcgtatttcatcaatgcag
agtgctactgagatgcagccatgccaaccttttctgcaggaggttcttccaagtggagct
gcactggctcgtaccttatcggagaagtcagggggcagcggctcagatgcatttagtgaa
ggtgactatgtgtttgaacctcccctcactggagaaagtggctctccacatggatataca
gatgacccagtgcacttgggcgaggatgagactgacagttgtttcttcgaagcagactgt
gtttcaccaagcattcccccacaccccctagctgagtatgtgaaccaaaaggagggagaa
cggaaccattcgcccataaaatctctgagaacatctgtttctaccctagagaggcaaaaa
cccacattggagaggcagaagtccacattggagaggcagaagtccactttggagaggcag
aagtccactttggagaggcagaagtccacattggacaggcagaagtccacattagagagg
cagaagggtcagcagtgcaagaatggcctgaggagcccacctcccttgtctgctctggac
aatccagactttttgcctccgccgagactaatcctgccaaacggctttccccaagccttt
gacaatccctattactggaatcatgaactgaacattgctaaggctgatggggatccgcag
gcacataacggatttactaccccaacagctgagaacccggaatacttggggctggatgat
accatgattagaccacgggacataactgtgtaa
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