KEGG   Xenopus laevis (African clawed frog): 108706593
Entry
108706593         CDS       T01010                                 
Symbol
kdr.S
Name
(RefSeq) vascular endothelial growth factor receptor 2 isoform X2
  KO
K05098  kinase insert domain protein receptor [EC:2.7.10.1]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla04010  MAPK signaling pathway
xla04020  Calcium signaling pathway
xla04370  VEGF signaling pathway
xla04510  Focal adhesion
Brite
KEGG Orthology (KO) [BR:xla00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108706593 (kdr.S)
   04370 VEGF signaling pathway
    108706593 (kdr.S)
   04020 Calcium signaling pathway
    108706593 (kdr.S)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108706593 (kdr.S)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:xla01001]
    108706593 (kdr.S)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:xla04090]
    108706593 (kdr.S)
Enzymes [BR:xla01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     108706593 (kdr.S)
Protein kinases [BR:xla01001]
 Receptor tyrosine kinases (RTK)
  VEGFR family [OT]
   108706593 (kdr.S)
CD molecules [BR:xla04090]
 Proteins
  108706593 (kdr.S)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ig_3 I-set Pkinase Ig_2 VEGFR-1-like_Ig-like VEGFR1-3_N_Ig-like ig Ig_VEGFR-1-like_5th VEGFR-2_TMD V-set Ig_4 C2-set_2 Adeno_E3_CR1 Ig_6 DUF1442
Other DBs
NCBI-GeneID: 108706593
NCBI-ProteinID: XP_018098634
Xenbase: XB-GENE-17339883
UniProt: A0A1L8HLA0 A0A974DU42
LinkDB
Position
1S:complement(29407685..29437231)
AA seq 1326 aa
MKAVLLGFLLLLLPLLGSLMASDFPSLSANKDHLVLAADETLNITCRGLRPVNWTWPINH
SNINNRLSVSECQESSYCLTLTLTKVVANDSGIYKCYYEDSNATNSVRVFILDKRSPFVP
SISEQPLAVYVTENKTVTVPCLASKPDLNVTLSAKYPSSTFHPDGIRIHWDNKKGFTILS
ELLKTVSLVSCETKLNGEVYSSPTYFVLVVGFKIYSLTMNPHPQVQLAVGEKLALTCTAR
TPLNVRIDYKWDYPAIMDKRVETKGHKKELRRELEFSGIFILNSVTLKDRGNYSCTAYTG
LMSKTSSTTVIVHEKPFITLDETMDSVIVTKVGQTVRIPVKYTAYPTPDIRWLKNGKPMP
HHIVKMENSLLINGTCEEDAGHYTVSLRNGQTKQQESHTFQLIVQVPPKIYEKAVPAPLD
SYKYSNPYILTCTASGIPNPVSIKWEWQLEDECSFYSHQYDIGKKPYTCASWRDISDKNG
GNVIETDETRTDVIEDKVKTVSKLIIRSARVSSLYRCSAYNQAGEDEHVISFHVTRGLEI
DMHPSSKLTERDNVTLLCTADKFTYENVTWFKLNPSRWSIPVCKNLVGLVKMHVSTTNTN
GNNVTSALILHNISMHEQGNYVCVAQDKKTQKRYCLVRHISIQAQKVPFIHHDLKNQTRN
VSETVVVKCQASGNPDPQILWFKDEDSLVEDSGIILKDGNRTLIIQRVRKEDEGVYSCKA
CNDLGCTKSEMYFTVNDTDEKTNLELIILVGTGIIALFFWVLLVIILRTVKRPNGGELKA
GYLSIIMDPGEVPIEEQCERLSYDASKWEFPRDRLKLGKLLGRGAFGQVLEADAFGIDKS
GTCKTVAVKMLKEGATTSEHSALMTELKILSHIGHHLNVVNLLGACTKPGGPLMVIVEYC
KYGNLSAYLRSKRSEFVLYKTKTPHYRKQHYVEVSRELKRRLDSIASSQSSASSGFAEEK
SLSDVEEEDTEVSEDTCKTPLCIEDLISYSFQVAKGMEYMGSRKCIHRDLAARNILLAEN
NVVKICDFGLARDVYKDPDYVRKGDARLPLKWMAPETIFDRVYTTQSDVWSFGVLLWEIF
SLGASPYPGVQIDEDFCRRLKEGTRMRAPEYATPEIYQTMLDCWHGDPQQRPVFSELVEH
LGNVLQASVQQDGKDYIPLTVSLNIEDDSGLSLPTSPVSCMEEEEVCDAKFHYDNTAGLR
FLQSSSKRQSRPVSVKTFEDIPVEPVMKVIQDENQTDSGMILASEELKTIQNKTDQTQFF
SKSKESVTSKSSNQTSDYQSGYHSDDTEAATDSNEKTQLLKRNSPSDNCHPDIIRHETVL
QLSTDV
NT seq 3981 nt   +upstreamnt  +downstreamnt
atgaaggctgtgctgctggggttcctgctactgcttctgccgctgctgggctcactcatg
gcttcagattttccaagtttaagtgctaataaagaccaccttgtcctagctgcagatgaa
acattaaatattacatgcaggggactgagacccgtgaattggacgtggccaataaaccac
agcaatattaataaccgcttatctgtcagtgagtgtcaagagagctcctactgtctgacg
ctcacacttaccaaggttgtagccaatgacagtggcatttacaagtgctactatgaagac
agtaatgctacaaacagtgttcgggtctttattctggataaaaggtctccctttgtgcct
tcaataagtgaacaacctcttgctgtttatgtcacagagaataaaactgtgacagtccca
tgcctggcttctaaacctgatctgaatgtcacactgtctgcgaaatacccaagttccaca
tttcatcctgatggtatcagaatacactgggataacaaaaagggatttaccatattaagt
gaattattaaagactgtgagcttggtctcttgtgaaaccaaactcaacggagaggtctac
agctcacctacttattttgtactagttgtaggttttaagatctacagcctgaccatgaat
ccccatcctcaggtacagctggcggttggagagaaactagctctaacatgcactgcacgt
actcctctaaatgtgagaattgactataaatgggactatcctgcaatcatggataaaaga
gtagaaacaaaagggcacaaaaaagaacttcgtagggaactggaattttcggggatcttc
atcttaaactctgtgacactgaaagacagaggcaattacagctgcacagcatacactggc
ctcatgtcaaagaccagcagtacaactgtgattgtacatgagaagcccttcataaccctt
gatgaaaccatggactctgtcattgtaaccaaagttgggcagacggtgagaatccctgtg
aagtacacagcataccctactcctgatatacgatggttgaagaatgggaaaccgatgcct
catcatatagttaaaatggaaaactctttattaatcaatggcacatgtgaagaggatgct
gggcattacaccgtcagtcttagaaatggtcagacaaagcagcaggaaagccataccttc
caactgattgtacaggtgccaccaaagatatatgagaaagctgtgcctgcccccctggat
tcttacaagtacagcaatccttatattttaacctgcacagcatctggaattcctaaccca
gtcagtataaagtgggagtggcagctggaagatgagtgttctttttattcacaccaatat
gatattgggaaaaaaccatacacatgtgcaagctggagggatatttctgacaaaaatggc
ggaaatgtgattgaaaccgatgaaactcgcacagatgtcatagaagacaaagtaaagaca
gtgagtaagttgatcattcgttctgccagagtatcttccctgtatagatgctcagcatat
aaccaagcaggagaggatgagcatgtgatctctttccatgttaccagaggcctagaaatt
gacatgcatcctagcagcaagctgactgagcgggacaatgtaactctcctatgcacagct
gacaagtttacttatgagaatgtcacatggtttaagcttaaccccagcagatggtcaata
ccagtgtgcaaaaacctcgttggcctggtcaaaatgcatgtctcaacgacaaataccaat
ggaaacaatgtgacctcagctctaatcctgcataacatttcaatgcatgaacaaggcaac
tatgtgtgtgttgctcaagacaaaaagacccagaagagatattgtttggtcagacacata
agtatacaagcacagaaagttcccttcatccaccatgatctgaagaaccaaactagaaat
gtcagtgaaacagtggtagtgaagtgtcaggcctctggaaatcctgatccgcaaatcctc
tggtttaaagatgaggacagccttgtagaagactcaggcattattttaaaagatggcaat
aggactttgataatccaaagagttaggaaggaagatgaaggggtctattcttgcaaggct
tgtaatgacttgggatgcacaaagtcagaaatgtacttcactgtaaatgacacagacgag
aaaacaaatctggagctcattattctggttggcaccggaatcatcgccttgtttttttgg
gtgcttctcgtaatcatcctccggaccgtaaagaggcccaatggaggggaacttaaggcc
ggctatttgtccatcattatggaccctggtgaagttccgattgaggaacagtgcgagcga
ctttcttatgacgccagcaagtgggagttcccaagagatcgtcttaaattagggaagctg
cttggccgtggggcttttggacaagttttggaagcggatgcctttggaattgataaaagt
ggcacctgcaaaactgtcgcagtaaaaatgctgaaagaaggggctaccaccagtgaacac
agtgcattaatgacagagctgaaaattctgagccacattggtcaccatttaaatgtcgtc
aacctgcttggagcctgcaccaaacctggaggtccattaatggtgattgtggaatactgt
aaatatggaaatctgtctgcttatttaagaagcaaacgaagtgaatttgtgttatacaag
actaaaactccccactacaggaaacaacactatgttgaagtttcaagagaacttaagcgg
cgcttagatagtattgcaagtagccaaagctcagccagctctgggtttgcagaagagaaa
tctctcagcgacgttgaggaagaagatactgaagtttctgaagacacttgcaagactcct
ttgtgtatagaagatctgatatcttacagcttccaggtggccaaaggcatggaatatatg
gggtcacgtaagtgcatccatcgtgacctagcagcacgcaatatactactggctgagaac
aatgtggtaaaaatctgtgactttggtctggcacgagatgtctacaaagaccctgattat
gtcagaaaaggagatgctcggcttcctttgaagtggatggcaccagaaaccatctttgac
agagtatacactacacagagtgacgtctggtcattcggagtacttctttgggaaattttt
tccttaggagcttcgccctatcctggtgttcaaattgatgaagacttctgcagacggtta
aaagagggaacacgaatgagggcgccagaatatgcgacaccggaaatatatcagacaatg
ctggactgctggcatggagatccacaacaaaggcctgtattttctgagctagtagagcat
ttaggaaatgtgttgcaagccagcgtgcaacaggacggtaaagactatattccacttacg
gtatctttaaacatagaagatgattctggcctctctctgccaacttcacctgtttcctgt
atggaggaagaggaagtttgcgatgcaaaattccattatgataatacagctggattaagg
ttccttcagagcagcagcaagagacaaagccgtcctgttagtgtcaagacatttgaggac
attcctgtagagcctgtgatgaaagtcattcaagatgagaatcagacagacagtgggatg
attctagcatcagaagagctgaaaacaatacagaacaaaacagaccaaacacagtttttt
agtaaaagcaaggagtctgttacatccaagtcttcaaaccaaactagcgactaccagtca
gggtaccattccgatgacacggaggcagctacagattctaatgaaaagacgcaactactc
aagagaaattctccatcagacaattgccatccagacatcattcggcatgaaactgttctc
cagttaagcacagatgtttaa

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