Xenopus laevis (African clawed frog): 108713394
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Entry
108713394 CDS
T01010
Symbol
gne.L
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00520
Amino sugar and nucleotide sugar metabolism
xla00541
Biosynthesis of various nucleotide sugars
xla01100
Metabolic pathways
xla01250
Biosynthesis of nucleotide sugars
Module
xla_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
108713394 (gne.L)
00541 Biosynthesis of various nucleotide sugars
108713394 (gne.L)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
108713394 (gne.L)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
108713394 (gne.L)
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Gene cluster
GFIT
Motif
Pfam:
Epimerase_2
ROK
DRTGG
FGGY_N
Hexokinase_1
Motif
Other DBs
NCBI-GeneID:
108713394
NCBI-ProteinID:
XP_018112050
Xenbase:
XB-GENE-17335381
UniProt:
A0A974E020
A0A1L8HXN5
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Position
1L:complement(119742966..119779785)
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AA seq
796 aa
AA seq
DB search
MFRILNRHNCIYTEPNQPCMITDCGLAVKPVEKNAHVPFALKSWGEILADKIRKRPRIYV
FALYFENLSRQKATMEKNINQRKLRVCVATCNRADYSKLAPIMFGIKAEPDHFELSVVVI
GSHLIDDYGNTYRMIEQDDFDIQARLHTIVRGEDEASMVESVGLALVKLPDVLNRLNPDI
IVVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHSITKLAHYHVCCTRSAEQ
HLIAMCEDHDRILLAGCPSYDKLLSVKNKDYMSVLKMWLGDDVKSREYIVALQHPVTTDI
KHSIKMFEFTLDALLSFNKRTLILFPNIDAGSKEMVRVMRKKGVEHHPNFRAVKHVPFEQ
FTQLVAHAGCMIGNSSCGVREAGAFGTPVINLGTRQTGRETGENVLHVRDADTQNKIIHA
LQLQFGKRYPCSKIYGDGNAVPRIVKFLKSVSLDEPLQKKFCFPPVKESISQDIDHILET
LSALAVDLGGTNLRIGIVSMKGEIIKKYVQPNPKTYEDRIELILKMCIDAAAEAVNLNCR
ILGVGISTGGRVNPQEGIVLHSTKLIQEWSSVDLRTPISDTLHLPVWVDNDGNCAALAER
KFGQGKGIEDFVTVITGTGIGGGVVHNHELVHGSSFCAGELGHIMVSFDGPECMCGSSGC
VEAYASGIALQREAKKLHDDDLLLVEGMTVKNDESVSAIHLIQAAKFGNTKAANILKTAG
TALGIGIINILHTINPSLVILSGVLANQYVNVVKDVIRQRGLASIQDVNVVVSNLSDPAL
LGAASMVLDYTTRRTY
NT seq
2391 nt
NT seq
+upstream
nt +downstream
nt
atgtttaggattttaaacaggcacaattgcatatatacggaaccaaatcagccctgtatg
atcactgactgtggcttggcggttaaaccagtggagaaaaatgcacatgtgccatttgcc
ttaaagtcttggggtgaaattttagctgataaaataagaaaaaggccaaggatatatgta
tttgcactctattttgaaaatttgtcaaggcaaaaggcaaccatggaaaagaacattaac
caacgaaagctacgtgtatgtgttgctacttgtaaccgagcggattactccaaactggcc
cctattatgtttggcataaaagcagaaccggaccactttgaactgagtgtagtagttata
ggctctcaccttattgatgactatggcaatacttatcgtatgatcgagcaggatgatttc
gatattcaggcaagattacatacgattgttagaggagaggatgaagcctcaatggtcgag
tcagttggccttgctttggtgaagcttccggatgttttaaatcgtttgaatccagacata
attgttgtccatggagatcgatttgatgcattggccttagcaacatctgctgcattaatg
aacattagaattcttcacatagaaggcggtgaagtcagtggtaccatagatgattctatc
agacactctatcaccaaactggctcattaccatgtctgctgcacccgaagtgcagaacag
catctgattgctatgtgtgaggaccatgacagaatccttttagcaggatgtccctcctat
gacaaacttctcagtgtgaaaaataaggactacatgagtgttctaaaaatgtggctcggt
gatgatgtcaagagtagggaatatattgtggccttgcagcacccagtgacgactgatatt
aaacattcaattaagatgtttgagtttacattggatgcccttctctccttcaacaagaga
acactaatactttttccaaacattgatgcaggaagtaaagaaatggtacgagtaatgagg
aaaaagggtgtggagcaccacccaaattttcgagctgtgaaacatgttccatttgaacag
ttcacccaattagtggctcatgccggatgcatgatcggaaatagcagttgcggagtccgt
gaagctggggcgtttggcaccccagtcatcaatttgggaactcgtcagacaggaagagaa
acgggtgaaaatgtgcttcacgttcgtgatgcagatacccaaaataaaataattcatgca
cttcagctgcagtttggaaagcggtatccctgttcaaagatctatggtgatggaaatgcc
gtcccacggattgtgaagtttttgaaatcagtcagtcttgatgaaccccttcaaaagaag
ttctgtttccctccagtaaaagaaagcatctctcaagatattgaccacattctggaaact
ttaagtgctttggctgtagatcttggagggacaaatctacgaataggcattgtcagcatg
aagggtgaaataataaagaagtatgtgcagcctaatcctaaaacatatgaggacagaata
gaactaattttaaaaatgtgtattgatgctgcagctgaagctgttaatctaaactgcagg
attctgggagtgggcatttctacaggaggtcgtgtaaacccacaggaaggtatcgtgctt
cattccacaaaacttatacaagagtggagctctgtggaccttcgaactccaatttctgac
acactacatctaccagtatgggtagacaatgatggcaattgtgctgcactggcagagagg
aaatttggccaaggcaaaggaatagaagactttgtgaccgttattactggcacggggatt
ggaggaggagtcgttcataaccatgagttggttcacggcagctctttctgtgccggcgag
ctgggccacatcatggtgtcctttgatgggccagagtgtatgtgtggcagcagtgggtgt
gtagaagcatatgcctctggaatagcccttcaaagggaagcaaaaaagcttcatgatgat
gatctgctgctggttgaaggcatgactgtgaagaatgatgaatctgtgagtgcaattcat
ctgattcaagctgcaaaatttggcaataccaaagcagccaacattctcaaaacagctggt
actgctctgggcattggcattataaatatcctccacactataaacccatcgctggtgatc
ttatcaggagtccttgcaaaccagtatgtgaatgtggtgaaggacgtgatacgccagaga
ggtttggcttcaattcaggacgtcaatgttgtcgtgtccaatttatcagatcctgctctt
ctaggagcggcaagcatggtgctcgattataccacacgcagaacatactaa
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