Xenopus laevis (African clawed frog): 108714085
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Entry
108714085 CDS
T01010
Symbol
hsd17b2.L
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00140
Steroid hormone biosynthesis
xla01100
Metabolic pathways
Module
xla_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
108714085 (hsd17b2.L)
Enzymes [BR:
xla01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
108714085 (hsd17b2.L)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
108714085 (hsd17b2.L)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
Epimerase
Motif
Other DBs
NCBI-GeneID:
108714085
NCBI-ProteinID:
XP_018113453
Xenbase:
XB-GENE-17343396
UniProt:
A0A1L8GL07
A0A974D2U9
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Position
4L:complement(57995873..58021604)
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AA seq
386 aa
AA seq
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MAQLDSRLLYLAVGVFFSGSALHKLMKNKVKIENASVPGLLSLLILGIFCFFILSDSFGL
TLLTLACTLYYYSIPVRNMLSAEGKSVLITGCDSGFGHALAKHLDELGVHVFAGVLDKKG
PGAEELKRVCSSHLCLIQLNITHSEEIREAYKEISSHVQDAGLWGIVHNAGVLGYVADGE
LIPFSVYKQCMDVNFLGAVQVTKIFVPLLRKAKGRLVSISSMGGHVPLKGFAAYASSKAA
LSMFSAVMRQDLSKWGVKVAVVCPSGFRTNIFGSQEQWWCQNQVILDDVMPDVKGDYGED
YIENFKGLYHTMHKFGSSDLSPVLEDVCHALLAQTPNPSYTPGRFAYLIPCLYYYSPQWI
SDRISMQSFQTQNNMLPRALRTKNKT
NT seq
1161 nt
NT seq
+upstream
nt +downstream
nt
atggcccagttggattccaggctgctttacttagctgtgggtgtcttcttcagtggatca
gcccttcacaaattaatgaagaacaaggtgaagattgaaaatgcctctgtccctggtctc
ctgtcactgctcatattggggattttctgtttcttcattttgtctgacagttttggctta
actctattaactctagcatgtaccctctattattattccatacctgtcagaaacatgtta
agcgccgaaggaaagtctgtgcttattacagggtgtgattctgggtttggacatgcacta
gctaagcacctggatgaactgggcgttcatgtctttgctggtgtgttggataagaaaggg
cctggcgctgaagaactgaaaagggtttgttcatcacacctttgcctaatccaacttaat
atcacccattcagaggagataagggaggcctacaaggaaatcagcagtcatgtgcaagat
gcaggactgtggggcattgtgcacaacgctggggtacttggttatgtggctgatggagaa
ctaattcctttcagtgtatataagcaatgcatggatgtcaattttcttggtgcggttcag
gtcacaaaaatatttgttccattgctgcggaaagccaagggaaggctagttagcatctcc
agcatgggaggacatgtcccccttaaagggtttgcagcatatgcctcatccaaggcagct
ctttcaatgttttctgctgtgatgcgacaggatctctccaaatggggtgtaaaagttgct
gttgtttgtccaagtggattccgaacaaatatttttggttctcaagaacaatggtggtgc
caaaaccaagtcattttggatgatgtcatgccagatgtgaaaggggattatggtgaagac
tatatcgaaaactttaagggcctctaccatacaatgcacaagtttggttcctctgacctc
tcacctgtcctggaagatgtgtgccatgctttactggctcaaaccccaaatccctcatat
acacctggaagatttgcatacttaatcccatgtttatactattactctcctcagtggatt
tctgataggatatcgatgcaaagtttccagacacaaaacaacatgcttcctagggcttta
aggactaaaaacaagacataa
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