Xenopus laevis (African clawed frog): 108716702
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Entry
108716702 CDS
T01010
Symbol
srd5a2.L
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00140
Steroid hormone biosynthesis
xla01100
Metabolic pathways
Module
xla_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
108716702 (srd5a2.L)
Enzymes [BR:
xla01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
108716702 (srd5a2.L)
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Motif
Pfam:
Steroid_dh
DUF1295
PEMT
Motif
Other DBs
NCBI-GeneID:
108716702
NCBI-ProteinID:
XP_018118564
Xenbase:
XB-GENE-6488238
UniProt:
A0A1L8G8B0
A0A974CW89
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Position
5L:52458834..52484096
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AA seq
254 aa
AA seq
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MQCNQDMDYYMSLCLAIISILFLIRQFTYPAAYGKHVVTGKKQTYFMVPAKYGWFIQELP
SFLVPVVVILYRQQCSSLGCKMLSFMFCGHYFHRTFIYSAFTRGRPSPIRIVLMAVVFCT
YNGFLQGHCMIYVATYPKDWCMDLRFLSGVLIFCLGMGINIHSDHILRKLRKPSEVAYKI
PQGGMFNYVSGANYLGEIVEWFGYAVATWSLPGFAFAFFTLCCIGPRACHHHKFYLQSFK
DYPPERKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcagtgcaaccaggatatggactattacatgagcctgtgccttgccattattagcatt
ctcttcctgatcagacagttcacttatcctgctgcttatgggaaacatgttgtcactggc
aagaagcaaacttatttcatggtcccggcaaagtatggctggtttatccaagagttaccc
tccttcctggtcccggttgtcgttatactttacagacagcaatgcagctcccttggctgc
aagatgctttcattcatgttctgcggacactatttccacaggacttttatctattctgct
ttcacaagaggaagaccatcacctatacgcatagttcttatggctgttgtattctgtacc
tataacggatttctgcaagggcactgtatgatttatgtagctacatatccaaaagattgg
tgcatggatctacgatttctatcaggtgtgttaatattctgtcttggaatggggatcaac
attcacagtgatcatattctacgcaaattaagaaaacccagcgaggttgcatacaaaata
ccccaaggaggaatgtttaattatgtatctggggcaaattatcttggtgaaattgttgaa
tggtttggatatgctgttgcaacgtggtcactgccaggatttgcctttgctttctttacc
ttgtgttgcattggcccacgggcttgccatcatcacaaattttacctccaaagttttaaa
gattatccaccagaaaggaaggctctgattccatttattttctaa
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