Xenopus laevis (African clawed frog): 108717870
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Entry
108717870 CDS
T01010
Symbol
pde10a.S
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00230
Purine metabolism
xla01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
108717870 (pde10a.S)
Enzymes [BR:
xla01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
108717870 (pde10a.S)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
108717870 (pde10a.S)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD-CE
HD
DUF7334
DUF4748
Motif
Other DBs
NCBI-GeneID:
108717870
NCBI-ProteinID:
XP_018120773
Xenbase:
XB-GENE-17336730
UniProt:
A0A1L8G297
A0A974CQZ9
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Position
5S:complement(46473846..46578801)
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AA seq
792 aa
AA seq
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MEDGPSSAGCFRRFTDCFLSTSLTDEKVKAYLSLHPQVLDEFVSESVSPETVEKWMKKKS
KNEDMTRTEVSRQYQDTNMQGVVYELNSYMEQRLDAGGDNKLLLYELSDIIKTATKADGF
ALFFLGECNNSLCLFTPTGTKDGQTQLTSVGPVEYGTTVSAHVAKSRNTVLVEDILGDER
FPKGTGLDSGTRIQSVLCLPIVTAIGDLIGILELHRHWGRESFHLCHQQVATANLAWASV
AIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDTLLEHIMIYAKNLVNADRCALFQV
DQKNKELYSDLFDIGEEDEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRF
NREVDVYTGYTTRNILCMPIVIRGSIIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALAL
HCANMYHRIRHSECIYRVTLEKLSYHSICTSDEWQNLMNCTLPVSLCREIELYHFDIQPF
EDLWPAIYVYMIHQSCGETCFELEKLCRFTMSVKKNYRRVPYHNWKHAVTVSHCMYLILR
NNQEIFTDLERKGLLVACLCHDLDHRGYSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSI
LQLEGHNIFSNLSSNEYEQVLEIIRKAIIATDLALYFGNRKHLEDLHQMGALNLNNQSHR
DRMIGLMMTACDLCSVTKLWPITRLIADDIYAEFWAEGDEMKRLGISPIPMMDRDKKDDI
PQGQMGFYNAVAIPCYTTLSEIFPSTRPLLQACKENLSQWEKVSRGEDTTVWIPSQSVPT
ESSDSLPVKIDD
NT seq
2379 nt
NT seq
+upstream
nt +downstream
nt
atggaagatggaccttcttctgcaggctgctttagaaggtttactgactgcttccttagc
acaagtctcacagatgaaaaggtaaaagcatatctctctctccatcctcaagttcttgat
gagtttgtatctgagagtgttagccctgaaactgtagaaaaatggatgaagaaaaaaagc
aaaaatgaagatatgacgcgtacagaagttagcaggcagtaccaggatacaaatatgcaa
ggagttgtatatgaactaaatagttatatggagcagcggctagatgctgggggagacaat
aaattactactttatgaattaagtgacattatcaaaactgctacgaaggctgatggattt
gcactattctttttgggagaatgcaataacagcttgtgtttgttcaccccaactggaaca
aaagatggacaaacccagcttacttctgttggacctgttgaatatggcaccacagtatct
gcacatgtagccaaatccagaaacactgtgttagtagaagatattctgggggatgaaagg
tttcccaaaggtactgggctggactcagggacacgtatccagtctgttctttgtttaccg
attgttactgcgattggtgatctgattggaatcttagaacttcatcgacattgggggaga
gaatcttttcatctttgtcaccaacaggtggcaacagcaaaccttgcctgggcttcagta
gcaatacatcaagtacaagtatgtagaggcttggctaaacagactgagctaaatgacttt
ctgcttgatgtatcaaaaacatactttgacaacatagttgcaatagatacattacttgaa
catataatgatatatgcaaagaacctggtgaatgccgatcgttgtgcactcttccaggtt
gatcaaaagaacaaagagttgtattcagatctttttgatattggggaagaggacgaggga
aagcctgtttttaagaagaccaaagaaattaggttctccattgagaagggtattgcagga
caggttgcaagaacaggtgaagtccttaatattcctgatgcctatgcagatccacgcttt
aatagagaagtagatgtttacacaggttacacaacgagaaacatcttgtgcatgcctatt
gtaatccgtgggagtattattggagttgtacaaatggtgaacaaactaagtggaagtgcc
ttctccaaaacagatgaaaacaactttaagatgtttgctgtcttctgtgctttggcctta
cactgtgcaaatatgtaccacagaatacggcattcagagtgcatttaccgagttacattg
gaaaaattgtcttatcacagcatttgtacttcagatgaatggcagaacctcatgaactgt
acactaccagtttctctttgcagggagattgaactataccactttgatatccagccattt
gaagacctatggccagccatatatgtttatatgattcatcagtcttgtggtgaaacctgc
tttgagcttgaaaagttatgccgttttaccatgtctgtgaaaaagaactatcggcgtgtc
ccctatcacaactggaaacacgcggttacagtatcgcactgcatgtaccttatacttcga
aataaccaggagatattcacagacttggagcgaaaagggcttctagttgcatgtttatgc
catgatcttgatcacagaggttacagcaacagctacctgcaaaaatttgatcacccttta
gcagctttgtattccacatcaacaatggaacaacaccacttctcgcagactgtatctata
ttgcagctggaagggcacaatattttttccaacctgagctccaatgagtatgaacaagtg
ttggagataatacgcaaagccatcattgccactgaccttgcactgtactttgggaacaga
aaacaccttgaagaccttcatcaaatgggtgcattaaatcttaataatcaatcacacaga
gatcgcatgattggtttgatgatgacggcttgtgatctttgctctgtaacaaagctatgg
ccaattaccagactgatagctgatgatatatatgcagaattctgggctgagggtgatgaa
atgaaacggcttggtatttcacctattccaatgatggacagagataaaaaagatgatatc
cctcagggccagatgggattctacaatgctgtagctattccatgttatacaactctttcg
gagatatttccttcaacgcgaccgcttcttcaagcgtgcaaggagaacctcagtcagtgg
gaaaaggtttctagaggagaagacaccacagtctggattccttcccaatcagtaccaaca
gagtcctctgattcactcccagttaagattgatgactga
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