Xenopus laevis (African clawed frog): 108718090
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Entry
108718090 CDS
T01010
Symbol
pik3ca.S
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00562
Inositol phosphate metabolism
xla01100
Metabolic pathways
xla04012
ErbB signaling pathway
xla04068
FoxO signaling pathway
xla04070
Phosphatidylinositol signaling system
xla04081
Hormone signaling
xla04140
Autophagy - animal
xla04150
mTOR signaling pathway
xla04210
Apoptosis
xla04218
Cellular senescence
xla04370
VEGF signaling pathway
xla04510
Focal adhesion
xla04620
Toll-like receptor signaling pathway
xla04625
C-type lectin receptor signaling pathway
xla04810
Regulation of actin cytoskeleton
xla04910
Insulin signaling pathway
xla04914
Progesterone-mediated oocyte maturation
xla05100
Bacterial invasion of epithelial cells
xla05132
Salmonella infection
xla05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
108718090 (pik3ca.S)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
108718090 (pik3ca.S)
04070 Phosphatidylinositol signaling system
108718090 (pik3ca.S)
04150 mTOR signaling pathway
108718090 (pik3ca.S)
09133 Signaling molecules and interaction
04081 Hormone signaling
108718090 (pik3ca.S)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
108718090 (pik3ca.S)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
108718090 (pik3ca.S)
09160 Human Diseases
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
108718090 (pik3ca.S)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
xla04131
]
108718090 (pik3ca.S)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
108718090 (pik3ca.S)
Membrane trafficking [BR:
xla04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
108718090 (pik3ca.S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_rbd
PI3K_C2
PI3K_p85B
DUF2321
ABC1
Ribosomal_S15
Retrotran_gag_4
Motif
Other DBs
NCBI-GeneID:
108718090
NCBI-ProteinID:
XP_018121180
Xenbase:
XB-GENE-17344667
UniProt:
A0A1L8G3Z7
A0A974HHZ9
LinkDB
All DBs
Position
5S:complement(95655069..95685148)
Genome browser
AA seq
1065 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRILVECLLPNGMVVVLECLREATLVNIKHELFKEARKYPLYH
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVVEPVGNREEKILNREIGFA
IGMPVCEFDMVKDSEVQDFRKNILNVCKDSVELRDANGPISRALYVYPPNVESSSELPKH
IESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHDCVPEHVIAEAIRKKTRSMLLSTEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQLPMD
SFTMPSYSRRISMAAPYMNGEASAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGVEPLCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVSGSNPNKETPCLELEFDCF
SSPVKFPDMTAIEDHANKVLEREMGYNYSHSGLSNRIVRENEVRESDKEQLKAISNRDPL
SEITEQEKEFLWSHRLYCRNVPEILPKLLLSVKWNCRDDVSQMYCLLKEWPAIRPEQAME
LLDFNYPDRIVRSFAVSCNEKYLTDDKLSQYLIQLVQVMKYEQYLDNHLVRFLLKKALVN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSKQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRLMSSAKRPLW
LNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGMQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGCGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKHL
NT seq
3198 nt
NT seq
+upstream
nt +downstream
nt
atgccgccaagaccttcctccggggagctatggggcattcatttgatgcccccaagaatt
ctagtggaatgcttattaccaaatggaatggtggtggtgttagaatgtcttcgtgaagcg
acccttgtaaatatcaaacatgagctctttaaagaggcccgaaagtaccctctttaccat
ctactccaggatgagtcctcttatatttttgtgagtgttacacaggaggcggaaagagaa
gaattttttgacgaaactcgccgtctttgtgatcttcgactgttccaacctttcttgaaa
gtagttgagcctgtaggaaacagagaagagaaaattcttaatcgagaaattggcttcgcc
attggaatgccagtgtgtgaatttgatatggttaaggactccgaggttcaggactttaga
aaaaacatccttaatgtttgtaaagattcagttgaacttcgtgatgcgaatgggccgatc
agcagagcattatatgtttacccacccaatgtagaatcctcttcagagcttcccaaacac
atagaaagcaaactagataaagggcaaataattgtggtcatatgggtcattgtatccccc
aacaacgaaaagcagaagtattctttgaagattaaccatgattgtgtgccagaacatgtc
atcgctgaagcaatccggaagaaaacaagaagcatgctgctgtccaccgaacaactaaag
ctttgtgttctagagtaccaaggaaaatacattttgaaagtctgtggatgtgatgagtat
ttgcttgaaaagtatccactgagtcaatataagtatattagaagttgtataatgcttggt
cggatgcctaatttaatgttaatggccaaagacagcctgtacagccaacttcctatggat
agctttacaatgccatcttattcaaggaggatttccatggcagcaccatacatgaatgga
gaagcttcagcaaaatcattgtgggcaatcaacagtactcttagaataaaaatcctttgt
gccacatatgtcaatgtaaacattcgagacattgataagatctatgttcgaactggtatc
tatcatggggttgagccgttgtgtgacaatgttaacactcagagggtgccttgctcaaat
ccaagatggaatgaatggcttttatatgatatgttcattcctgatttaccacgagctgca
cgactttgcctctctatttgctccgtaaagggacggaagggcgccaaagaagaacactgc
cctttagcatggggaaatattaacctgtttgactacacagatacactggtgtctggaaaa
atggctctaaatttgtggcctgtgcctcatgggttagaagacttgctaaatcctattgga
gtcagtggctccaatcctaacaaggaaacaccctgtttggaactagaatttgactgtttc
agtagcccagtcaaatttcctgatatgaccgcaatagaagatcatgcaaataaagttctg
gagcgggaaatgggctataattacagccattctggactaagtaacagaattgttagagaa
aatgaagtaagagaaagtgacaaggagcagctcaaagccatttctaaccgtgaccctctc
tctgaaattactgaacaagaaaaagaattcctttggagccacagactgtattgtcgaaat
gtacctgaaattcttcctaagctgcttctgtctgtgaaatggaattgcagagatgatgtt
tcacagatgtattgtcttctaaaagagtggcctgctatccggcctgaacaagcaatggaa
ctgctggattttaattacccagatcggattgtacgatcatttgcagtttcttgcaatgag
aagtatctgacagatgataagctatctcagtatttgatccaacttgtgcaggttatgaaa
tatgagcagtacttggacaaccatctagtgagatttctgctgaaaaaggccctggtcaat
caaagaataggacatttctttttctggcatttaaagtcagaaatgcacaacaaaactgtc
agccagcggtttggtcttttgctggagtcctattgccgtgcatgtggaatgtatttaaaa
catttaagcaagcaagtggaggctatggaaaaactgatcaacctcacagatattctaaag
caggagaagaaggatgagacacaaaaggtgcaaatgaagttcctggttgaacaaatgaag
cggccagactttatggatgccttacagggatttacatctcctctaaatcctgctcaccaa
ttaggaaacctaaggcttgaagagtgcagactaatgtcatctgcaaaaaggccactctgg
ttaaactgggaaaatccagatataatgtcagagatgctgtttttgaataatgagatcatc
tttaaaaacggagatgatttacggcaagatatgctcacgctccagatcataaggatcatg
gaaaacatttggcaaaatcaaggccttgatttacggatgttgccatatggttgcctgtca
attggagactgtgtcggacttattgaagtagtgagatgttcacataccattatgcagatt
cagtgcaaaggaggtctgaaaggagcattgcaattcaacagtcatacattgcatcaatgg
ctcaaggataaaaacaagggggaaatgtatgatgccgccattgatctgttcactcgatcg
tgtgctggttactgtgttgcaactttcattcttggaataggtgatcggcataacagtaac
attatggttaaagacaatgggcaactgtttcacatagattttggccactttttggatcac
aaaaagaaaaaatttggctataaacgtgaaagggtaccgtttgtcttaactcaagatttt
ctgattgtgatcagcaaggggatgcaagaatgcacaaaaaccagggattttgaaagattt
caagagatgtgttacaaagcgtatttagcaatccgccagcatgccaaccttttcatcaac
ttgttctctatgatgcttggctgtggaatgcctgaactacaatcttttgatgacattgcc
tatattcgaaagacattagctttggataaaactgagcaagaggctttggaatacttcatg
aagcagatgaatgacgcacatcacggtggctggacaacaaaaatggactggatcttccat
acaataaagcatctttaa
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