Xenopus laevis (African clawed frog): 108719653 Help Entry 108719653         CDS       T01010                                  Name (RefSeq) obscurin isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism xla  Xenopus laevis (African clawed frog) Pathway xla04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:xla00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     108719653  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:xla01001]     108719653   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:xla04131]     108719653 Enzymes [BR:xla01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      108719653 Protein kinases [BR:xla01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    108719653 Membrane trafficking [BR:xla04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     108719653 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_4 Izumo-Ig Ig_5 Ig_6 V-set_CD47 SOS1_NGEF_PH C1-set C2-set_2 RhoGEF fn3 PH IQ RHG20_PH Egh16-like IQ_SEC7_PH Motif Other DBs NCBI-GeneID:  108719653 NCBI-ProteinID:  XP_041423262 UniProt:  A0A8J1L139 LinkDB All DBs Position 6S:complement(5398692..5532680) Genome browser AA seq 7439 aa AA seqDB search MDYSSFSGVPRFLTRPKAFMMSVGKDSTLSCQIIGNPTPVVTWDKDKLPIKSEGRFKMIE DGNLYRLTIYDLQFGDSGQYICRAINTIGEAFAAITIKVGDEKEGTVAECAPFFILKPIT TKINLGEDATFQCRVQGNPPPAVKWEKDGKILGKSFDSNRIRIIDNGESSSIKINCIRFS DSGTYLCRAENPVGQATASASLLIDSFSNSTSALEPTYAKTTSLLSHLQKRREEMRKSDT SVISTVDTNANSYGAVDPVSSLGFSLSLDYERAASLTPKISRDGTFGVLTRTCTVTEGKH AKMSCYVTGEPKPEIVWKKDGDIISEGRRHVIYEDEQENFVLKILFCKQIDNGLYTCRAS NLAGQTYSSVLVIVNEPRIPFKTKLRDVEVREKESATFQCEVPSAITESSWYKEETQIEQ SSKYNIEEEGSIRRLTIQNVTADDDAVYICEMKEGSRTIAELSVQGNIIKKLPRRTAVPI SDTAMFCVELDNECQKIKWLNNGQEVKPGGRISISSSRKQHTMTIRECQNSDAGEITFIA DECRTSTKFTVTCLRKPPSNAPTNPMVKDKTETSVTLVWSPPPMDRPVPIDGYIVERKKL GATAWLRCHESTNVPVPQFTINNVFDEGSYHFRVSAVNTYGQSPYLEFPGTLHLEPVPSV KTPLRPAEVTLGGEATFTIDLSTVSSGVWLINGKIIQNSERYTIRRVKNTHTLIIQSITQ ADHETEVKFNSNGIESSAKLMVKALPQFTNSKKINDVKVVAGEQAELISETSEENVKVLW YKDNKEIRQSKKFSLEVKGKQHKLLVTAVKKEDEGTYSCKTADDSVGFTLKVTEHEPVFM NQDKVQKEFQATLTESVTLKCEVSQSKTEVKWYKEGKLISSSKRVRMESEGKSRRLVVEQ LEKKDAGEYSCEAAGEKINFRIKVIEPEPAFSNLEKVQKEVQATLNESATLSCEVSQAKT EVKWYKEGKVITSSKKMRVESKGKSRCLVVEKVEKQDAGEYSCEAAGQKINFKINVKEHE PAFTNTDKIQKEVQVTLNESATMSCEVSQAKTEVKWYKEGKLITSSKKMRVESKGKSRCL VVEKVEKQDAGEYSCEAAGQKINFKINVKEHEPAFTNTDKIQKEVQATLNENATMSCEVS QAKTEVKWYKEGKLITSSKRVRVESEGKSRRLVVEKVEKQDVGEYSCEAAGQKINFKVTV KESEPAFTNQDKVQKEVQATLTESATLSCEVSQAKTEVKWYKEGKVITSSKKMRVESKGK SRSLVVEKVEKQDAGEYSCEAACQKINFKINVKEPEPAFTNTDKIQKEVQATLNENATMS CEVSQAKTEVKWYKEGKLITSSKRVRVESEGKSRRLVVEKVEKQDAGEYSCEAAGQKINF KVTVKEPEPVFTNQDKVQKEVQANLTESATLSCEVSQAKTEVKWYKEGKLITSSKRVRVE SQGKSRRLVVEKVEKQDAGEYSCEAAGQKISFKINVKEPEPVFANQEKVQKEVQATLTET ATLSCEVSKTKTEVKWFKDGKQITASKKIKVVSEGKSRRLVVEQLEKKDAGLYSCEAAGQ KISFRINVKEQEIVFTNQEKVQKEVQATLTESVNLSCEVSQAKTEVKWYKDGKQITTSKK FKVVSEGKSRQLVVEQMEKKDAGEYSCEAAGQKISFKITVKDSELAFINKEKIQKEVQAT LNESATVCCEVSQDKTEVKWYKDGKLITSSKRVRLESEGKSRRLVLEKTEKQDAGEYSCE AAGQKINFKIKVKEPEPVFTNQEKVQKDIQATLTESSTLSCEVSQAKTEVKWYKDGKLIT SSKRVRVESEGKSRRLVVEKVEKQDAGEYSCEAAGQKINFKINTVEAQAKFLKKPSKQEP ILVQEDEDIILKTSVQPENTEVRWFKDGKELTATKKYQISAEGATRTLVVKVAESKDSAS YSCTTKSDKQEFKVQVKEIPQKFQKKLEAVCGEIGSNITLTCELSQAKVDVIWRKNGQEI KAGKHFAIRSDGAKRILTISGLKADDEGEYSCESRDDKTITQLTTKAPRVVKFTGELSNA VMEEGGEATLKCTISLDDAVVTWYRNGVKIESNKKYTINKKGTNHSLTIKELVLQDAGEI MAESEGIQTKASLKVREKPLTFKKKLEAITVEERQTVRFEVEVSKATKEVKWMKNSIVLQ PSENIEIQSEGTKQILILKNVTYTDRGLYCCETLDDKTQAKLNVEMRQVKVAKGLKDVEV HEKDSATFELELSHEDVEGFWMKDGIKLKPSDTCKMTFKGKKHSLTLSSLKMDDSGPVVF KSEGLQSSAKLTVKEPPVKITLPLKDIKAPEKEKVTFECEVSRPNAEVKWFKDGSGLKPS KKVAIISQAKKRSVTIHKCEREDQGTYVCDAGEDKTSAYLTVHGRDIQIVKPLVDVEVVE KESASFMCQISHDEVQTQWYKNGIKLKAGENVKMRQEGRTYSLVFQSVQAEDAAEIKFVA EASESRAKLKIKELPLKIVKPLRDKIAIEKHRAFLECQVSRASAEVTWYKKNKQIAPGDK YEIVSQGLYRKLIINEAEFEDEDTYTCDAGDDKTSAKLLIEEQSINIVKELADVEVTQPE SATFECVTSIVSVKPPKWSLGGEVLCDGKGITIEQDGTVHRLTLRKTSPEMSGAVQFHIG KSKSSAKLLVKEIPVRLTQRIEDKTANERQTVILSCEFKPPPKFVEWFKDKSQIEPSERF KLKLERNMAELKILQVTPEDSGTYTCKAGDAETSGNLNVHARDVKVLKPLKDVEVEEESC AVFSCELSHDDEEVEWFLNNTLLYSNNFNDIQKIGATHTLTLKQVAPEDSGTVSVKTKKL SFSAQLKVKEKTAVFMKSLDDAVGEERGMVTLGCEVSKAKVKPVWKKDNQVLPNGDKYQQ MQAGKTVCLIIHDLNKSDAGLYICDIGTDTAKSKISVQELNIGITKRLKSSEAKEGESCT FECILSHESIDECSWTVNGQSVEGDQRFNVSNKGRKYVLHIKEVRARDAGEVIFTARNLN SKASLTIKEKPSEIIKPLEDKTVPVGEDVILKCELSKEDANVKWCKDGKVLKKSQKYEFF QEGTETRMTIHEVTSKDSGEYTCETSISQTKASVQIKEKPNWFKKELSDINIEEGESAVF NCETEKKASSVTWRKGIMEIKSSEKYEISQKGNALSLQVNDLEKSDSDLYVCDIKDAQTK ANLTVKAPQAYFKRELQSTEAVEGETATLWCELSNPDAEVEWSKDGNVLKASKKHEMRVR DHRVELLIHHLVEEDAGTYKCGTGERTSSATLTVKVEQVLFKRGLRNEKAKEGGSVKLHC ELSKASASVRWMKGSQVLENGEKYNMKLVGTVAELFILNAKTEDSGDYTCDIGDQKSTAN VTVTALPVRFKQDLKDAEIEEGSSVTLSCEVTKPDAPVTWKKGITTLQANEKYEFRQKGC LVDLIIHKAGPEDSGTYTCDTGNQQTSARVKVKELPALFKEELKHQKVSEGECASLRCEL TKANASVEWKKDHRMIKQSKKYKIRQEGAVSELEIRDLVLEDSGDYSCVCGDHKSTATVT VAASPPRFSEELRDEKATEGQQATLHCELTKPGAVLEWTKGQSFLKPGGKYSMRQEGLSA ELLISNLEERDSGDYTCVCGDQQTTATLTVNALPVFFKKNLRDTVATEEEMVTLHCELSK PATKVEWKKGHRLLKGSDKYTMKLEGLAAELSISDLNVKDSGEYTCVCGDQETTANLTVN ALPILFKEELSNKESPEGEKVALCCVLTKAPGHVEWRQGHKALKSSPKYEMRVDGASAEL IIHNLELKDMGEYTCVCGEQQTTAVLIVNALPTHFKHGLKDENIKEGDRAILHCELSKPD VTVQWRKNSEDLVTSEKHILRQDGSIAELVIPHLEEEDSGVYTCICGDVKTTSTLSVIAL PPRFKEDLKNKEAVEGDSVTLRCELTKSNASVGWRRGQEALRPNDKYKMRQEGLVAEILI SQLDLQDSGKYTCFCGDHETTAMLTVNAVPPQFKEELRSKEAVEESSVVLTCKLTKPNAL LEWRRGHKTLKTCDKYKMIQEGLEAELVINNLDLKDAGEYTCVCGVHQTTASLTVNELPA LFKEEIKHAEEREGQKAVFHCKLTKPNARVEWKKGHETLQPSDKHQLMQDGVIAELTISK LELKDSGNYTCVCGEEATTASLTVTELPAVFNADLKNVEVTEGVTATLHCGVTKASASVQ WMKGNQALRSNDKYHMKQEGCEIELLICDTDLDDADQYTCICGDQKTSAILTVNALPVVF KEELKNTEVTESDTATLHCALSKPNVFVEWKKGTQVLSQSQKYSFRQEGSSADLVINNID PKDAGEYTCTCGDKKTSAVVTVNALPCVFTKPLQNTEAEEGDTLTLRCEVSKPNVSVEWR KGSLGLQQGSKYEIRQKDCVAELIIHNLRLEDTGEYSCDTGDQETRAYLTVKALPVLFKK PLKDTTVEEGVNVTLRCETTKPNVPIEWRKGTIGLFPCAKYEMRQEGVAAELVVYDVEAG DGDEYTCDTGDQQTTATIKVSVLQFLQNLQNMEAQEGGKARFRCEVSSKKNLVEWRKGAQ TLQASSKYEMKEQDGVRELIIHNLELEDAGEYTCLSRSKKSSATLKVNELDVTIVKGLKD VSVFAAEDAVFTCELSHPDAKDVEWKLQGITLANNEMNEISVEKGKIHRLKLSSVTQEDT GSITFRVGPYTSTAELTVKAPLPVFTKNLLDIQVEEDGSVVLECELSQPSVPVVWRKGTE QISASAKFDIKELGAVHSLQINNLKPEDSGVYTCDIGHQQTKAKVTVTALPVQITKPLQN EQGEENKYVILRAEVSKSNAPIQWKKAGVTLQPGSKYEMKQAGHVVELHILKLQMSDAGE YTCDTGDQKSVANVCVKEPEPFIIDHLQNVSVEEGEDAIFKCKVSKENAPDVQWCLAGVP LQSNEMNEISCHKGKIHTLTLKKVSTQDTGIVSFRVGQNTTSAELSVTAVALTFTKKLQP VEGEEQGVAVLQCEISKVNVPVEWRKGSKIIIHGGRYEISMNGSVHTLCIKDLTSEDSEE YSCSAQSEATSARLQVNQLPVTFTQELQNVEPEEGGTASLQCKVSRADAHVEWRKGALVL QTSAKYEMKQSGSLVELLIHNVDLEDCGPYTCSTDTAQTTASVFVQAKNKVLQELENIDA VEGGEALFECYLSKPECYNYNWLLDDEPARTSENIEMIYFENGRRHLLLLKNLTSQESCR VTFIAGAAVTSAFLNVQGWRLEVLKPPVDTEVIAGGQATFSCILSEAIPVNEVAWYFNGV DIQPDENWAMQVDGNEYKLILKDAQLHHSGEVAFASRDVVASAKISVLEHPITIKHQLEN KNLKEGETIRLECEFSKETRDVKWMKGSEILTSGGKYEFVCQGQKQVLIIHNSSSDDQGS YTCATSSGDKTTASVTLEKQIITEVMSIQEIFGLAQERTDIKHEDEESQPSLPPEAAQEG DLHLLWEALAKKRRMSREPTLDSISELPEEEEKRRQKKEAERHSDFSGYTSDDLTKTSEA DFSVTSSDDESRAGTPSLVTYLKKAGHSTVTHRSKVHKVSESKFFKHFETKEIERKEIKE PPQEPEIPDLFHDDDPALDKAAVKIQAAFKGYKARKVIKQQECPLFAETFKDLSVEPGGT VHLECVAICKTDITARWLKDNKELSDGRHYHIDNYPDGTCSLIITAVETADTGIYTCEAS NKFGAVSHSASLVVGSGLPEVTLKPKPLIVKYGSDSETESTTGSDLDDAFRKAGRRLHKI FKSKTSLEMSDVEEELFVSADEGDLPPVDQQTYREDDKYIYIKFEVMSEASFAAKRFKEM FSAMGIPVKIDILDQGAKNIDLRIMKVETGTTEQQRMAARHQMTLLTSDTAPIFITELQN QEVQDGYPVSFDCVVIGRPMPSVRWFKDGKVIEEDDHYMINEDQEGCHQLIITAVVPKDM GVYRCLAENRMGVSSTKAELRVDLTSSDYDTAEATETSSYFSAQGYLSREQEGLESATEQ DQLPQILEELRDTMVAPGTPLTKFEIKVKGYPRPRVYWFKDGQPIHASDRILMTDKKKLH SLEILNVTKEDAGEYSTYISNSAGSAYSSARLSVKGPDELQKDKPMEDAVDGEKPVPPRF LERFTNKKVLKGASITLSVKVEGIPPPTITWLKEDSPEDVLWIKPDTPGYKMASSNRHHS LILLDVGTEFSGTYTCIATNKVGQSICTASVEIAEAKEAKILKEADKLVKEMLGRTSLPG FEEGRETESGVIGISVQPPEDSGEVSKPHISLTDVGTEEFFQKLTSHITEMVSAKISQAS LRVPGTTGMDSDDETKTPSASPRHGRSRPSSIAVESSSESEDGDSRGEIFDIYMASADYN PIVADKESITLKEGQYVEVLDSAHPLKWMVRTKPTKFSASRQGWVSPAYLDKRLKLSTEW TAGEAPELSGVCVSEEEYKKKLSILIQELLNTEKEYVKELQFLENHHLHHTEHWPDIPES VASQKSTIFRNISDIGNFHSSIFFPELKKCDTDDDIAMSFIKNEDEFNKYIMFLVGRVQA ESVVLSDSIQEFYKNYSEERLALSDPSKPPVPPLQHYLEMPINRIQRYQVIIKELIRNKA RNGKNCALLEQAYAIVSALTRRAENFLHVSMIENYPGTLEVLGEPIRQGHFIVWEGAPGA RMAWKGHNRHVFLFKNYLIICKPKRDTKTDTYSYVFKNMMKLTNIDINDQIEGDDRAFEV WHEREDSVRKYLLQARTVIIKNSWVKEICGIQERFSMPVWNPPKFIEILADCTAELGETV KLACRVTGTPKPVVAWYKDGRPVEADPHHIIIEDPDGSCTLILDNMTGADSGQYMCFAAS PAGNASTLGKILVQVPPRFVNKLRNAHFVDGEDSQFTCTIEGAPYPQIRWYREGKLLSES AKHQTFTEPRSGVLVLVVKNATNDDLGYYECELVNRLGSARSGAELSPMTPALLAQERRG DQTITIEVTEQETKVPKKTIIIEETITTVVKSPRMRRRPGFSPSRPASASPSRQPRSEMS TPEPHFVTRAKQFVHRPEQEIRKTVLPTLFVTEPEDERGSHSRVEEQKPRYFEVEEIIEF KVKKSPLPPRKRGTSPAKPEKDDFSGRKFTRPRRSPHDDPNTNNSNNKSLEESNSSLSSC GLSDTDITSMDYGLIEEDSYLDDNLHLQCVSEEDNDSFSNDITAANGYSAVQHRNSPTQT ETKVELSVSNEIESSALGTKENVSELQNSEQEMPFEVEDVIVEEPPEEEEDNELKNRDKK ILTCDGKVLTFEDLEDYVPGQGETYGCGENDSYISKDEPCEISVLQAEINEPTIGKPVLL NVGRPVVPKPRQSFFHNFKENITGGIFMAASRMSRMNLMGSSNVSFSMNETSMAGASVSS PSSALPSFNIKPSYCTEVQRSVDNGPPSFKTEVSTRTLSYGTLGETVTLHISKKDPSNC NT seq 22320 nt NT seq  +upstreamnt  +downstreamnt atggattacagttcatttagcggggtgccacggttcctcaccaggcccaaggccttcatg atgtctgtggggaaagattccaccctgagctgccagattataggaaacccaactcctgta gtcacatgggataaggacaaactcccaatcaaatccgaaggtcgtttcaaaatgattgaa gatggcaacctgtatcgactcactatttatgatctacaatttggagacagtggtcagtac atttgtcgggcgatcaacaccattggtgaagcctttgcagccatcaccatcaaagtaggg gatgaaaaggaaggcactgttgcagaatgcgcacccttctttattttgaaaccgatcacc acaaagattaatctaggagaagatgccacatttcagtgcagggtccaaggcaatccccca cccgcagtgaaatgggaaaaggacgggaaaattcttggcaaaagttttgactcaaatcgc attcggattatagataatggagagtccagctctataaagataaactgcataaggttttca gacagtggaacgtatttatgccgggcagagaatcctgtaggccaagccactgcttccgca tcattgttgattgactccttttccaacagcacatctgctctggaacctacctatgccaaa acaacttctctcttatctcaccttcaaaaacgacgggaagaaatgaggaaatcagacaca tcagtcattagtactgttgacaccaatgctaattcgtatggagctgtggatccagtatcc agcctgggctttagcttgagtcttgactatgaaagagctgcttctctcacaccaaaaata agtcgtgatggaacatttggtgttcttacccgtacttgcacagtaactgaaggaaagcac gccaaaatgagttgctatgtaaccggggagcccaaacctgaaattgtctggaagaaggat ggcgacattatttcagagggacggaggcatgtcatttatgaggatgagcaagagaacttt gtattgaaaattttattctgcaagcaaatcgacaatggcttgtacacctgcagagcctct aatctggcgggacagacctacagctcagtgctggttatagtaaatgaacctagaatccct ttcaaaacaaaactgagagatgtggaggtcagagagaaagaatcagccaccttccaatgc gaggttccaagcgccatcacagaatcatcttggtacaaggaggaaacccagatcgagcaa agttccaagtacaatattgaagaggagggatccatcagaaggctcaccatacagaatgtc accgctgatgatgatgccgtgtatatctgtgaaatgaaggaaggcagcaggacaattgct gagctctctgttcaaggtaacatcatcaaaaagcttccaagaaggacagcagttccgatc agtgatacagccatgttctgcgtggagctggataatgaatgccagaaaatcaaatggtta aacaatggtcaagaagtaaaacccggaggacggatttccatcagttcctcacgcaaacag cacactatgaccatccgcgaatgccagaatagcgatgccggagagataaccttcatagcc gatgagtgtagaacgtccaccaagttcactgtcacctgtttacggaaacccccttctaat gcgcccactaaccccatggtgaaggataaaacagaaacatcagttacattagtctggtcc cctcccccaatggatagacccgtgcccattgatgggtacatcgtagaacgtaagaaactt ggagccaccgcctggctaagatgccacgaatcaaccaatgtgcctgttccgcagttcacc atcaacaatgtttttgatgaaggaagctatcatttccgtgtcagtgctgtgaacacctat gggcagagcccttaccttgagttcccaggaactctgcatcttgaacccgtaccttctgtt aaaactcctttaaggcctgcggaagtcactttgggtggtgaggcaacatttacaattgac ctaagcactgtatcttcaggcgtctggctgatcaatggaaaaataattcagaacagtgag cgatacactataaggcgggtgaaaaatactcacactcttattattcagagcatcacccaa gctgaccatgaaacggaagtgaaattcaacagtaatgggatcgaaagcagtgctaagctc atggtgaaagctcttcctcagttcaccaactccaagaagatcaatgatgtaaaggtggtc gctggagagcaggcagagctcatctcagagacttcagaggagaacgtgaaggttctgtgg tacaaagacaacaaagagatccgacaatccaaaaagttttcactggaagttaaagggaaa cagcacaaactgcttgtcactgctgtcaagaaggaagacgaggggacatactcttgcaag actgccgatgactctgttggtttcactttaaaagttacagaacatgagccagtgtttatg aaccaagacaaagtacagaaggaatttcaagccacactgacagagagtgtcaccctcaaa tgtgaggtgtcccagtccaaaactgaggtgaagtggtataaggagggcaaacttatcagc tccagcaagagagtgaggatggagtctgagggcaaatcccgtcgcttggtggtggagcag ttggagaagaaagatgctggagagtacagctgtgaggctgctggagagaagattaacttc agaatcaaagttattgagcctgagccagcatttagcaacttggagaaagtgcagaaggag gttcaggccaccctgaatgagagtgccaccctgagctgtgaggtgtcccaggccaagact gaagtaaaatggtacaaggaaggcaaagtgatcacctcaagcaagaaaatgagggtagag tctaagggcaaatctcgctgcctggtggtggagaaagtagagaaacaagatgccggagag tacagctgtgaggctgccggccagaagatcaattttaagattaatgttaaagaacatgag ccggcattcaccaatacagacaagatacagaaagaggttcaggtcaccctgaatgagagt gccaccatgagttgtgaggtgtcccaggccaagactgaagtaaaatggtacaaggaaggg aaactgatcacctccagcaagaaaatgagggtagagtctaagggcaaatctcgttgcctg gtggtggagaaagtagagaaacaagatgccggagagtacagctgtgaggctgccggccag aagatcaattttaagattaatgttaaagaacatgagccggcattcaccaatacagacaag atacagaaggaggttcaggccaccctaaatgaaaatgccaccatgagttgtgaggtgtcc caggccaagactgaggtgaagtggtacaaggaagggaaactgataacctccagcaagaga gtcagggtggagtctgaagggaaatctcgccgcctggtggtggagaaagtggagaaacaa gatgttggagaatacagctgtgaggctgccgggcagaagatcaattttaaagttacagta aaagaatctgaaccagcattcaccaaccaagataaggtacagaaggaggttcaggccacc ctgacagaaagtgccaccctgagctgtgaggtgtcccaggccaagactgaagtaaaatgg tacaaggaaggcaaagtgatcacctcaagcaagaaaatgagggtagagtctaagggcaaa tctcgcagcctggtggtggagaaagtggagaaacaagatgccggagagtacagctgtgag gctgcctgccagaagatcaattttaagattaatgttaaagaacctgagccggcattcacc aatacagacaagatacagaaggaggttcaggccaccctaaatgaaaatgccaccatgagt tgtgaggtgtcccaggccaagactgaggtgaagtggtacaaggaagggaaactgataacc tccagcaagagagtcagggtggagtctgaagggaaatctcgccgccttgtggtggaaaaa gtggagaaacaagatgctggagaatacagctgtgaggctgccgggcagaagatcaatttt aaggttacagtaaaagaacctgagccagtgttcaccaaccaagataaggtacagaaggag gttcaggccaacctgacagaaagtgccaccctgagctgtgaggtgtcccaggccaagact gaagtgaagtggtacaaggaggggaaactcatcacctccagcaagagagtcagggtggag tctcagggcaaatctcgccgtctggtggtggagaaagttgagaaacaagatgctggagaa tacagctgtgaggctgctgggcagaagatcagttttaagatcaatgtcaaagagccagaa ccagtgttcgctaaccaggagaaggtgcagaaagaagttcaggccaccttaacagaaact gccaccctgagctgtgaagtgtccaagacaaagacggaggtgaagtggttcaaggatggg aaacaaatcaccgccagcaagaaaattaaagtggtgtctgagggcaagtcccgccgactg gtggtggagcagttggagaagaaagatgctggactgtacagttgtgaggctgccgggcag aagatcagtttcaggataaatgtcaaagagcaagagatagtgttcaccaaccaggagaaa gtacagaaggaagttcaggccacccttacagagagtgtcaacctaagctgtgaagtgtcc caggccaagaccgaagtgaagtggtataaggatgggaaacaaatcaccaccagcaagaaa tttaaggtggtgtctgaaggcaagtctcgtcagctggtggtggaacagatggagaagaaa gatgctggggagtacagctgtgaggctgctgggcagaagatcagcttcaagatcaccgtc aaagattctgagctggcatttatcaacaaagagaagatacaaaaggaggttcaggccacc ttaaatgagagtgccaccgtttgctgtgaggtgtcccaagataagactgaagtgaagtgg tacaaagatgggaaactcatcacctctagcaagagagtaaggctggagtctgagggcaaa tctcgccgcctggtgctggagaaaacggagaaacaagatgcgggagaatacagctgtgag gctgccggacagaaaatcaatttcaagatcaaagtcaaagaacctgagccagtgttcacc aaccaagagaaggtacagaaggatattcaggccaccctgacagagagttctactctgagt tgtgaagtgtcccaggccaagactgaggtgaagtggtacaaagatgggaaactcatcaca tccagcaagagagtcagggtggagtctgagggtaaatctcgtcgcctggtggtggagaaa gtggagaaacaagatgctggagagtacagctgtgaggctgccgggcagaagatcaatttc aagatcaatactgttgaagcacaagccaaattcttgaagaagccatcaaagcaagagcca atccttgtccaagaggatgaagacattatactgaagacctctgtccaaccagaaaatact gaggtcagatggtttaaggatggaaaggagttgacggcaacaaagaagtaccaaatatct gctgaaggggccacaagaactttagtagtaaaggtggcagagagcaaagacagtgcaagt tactcctgcacaacaaaaagtgacaaacaggaatttaaagttcaggttaaagaaattccc cagaagtttcagaagaaactagaagctgtctgtggggaaataggaagcaacatcactctg acctgtgagctgagccaggccaaagtagatgtgatctggcgcaagaacgggcaggaaatt aaagctggaaaacattttgcgatcagaagcgacggggccaagcgcatattgaccatctca gggctcaaggcagatgatgaaggagagtactcatgtgaatccagagatgacaagaccatc acccaactgacaaccaaagcaccaagagtagtgaagttcactggagaactcagcaatgca gtaatggaagaggggggtgaagccaccctgaaatgtaccatctccttggacgatgcagtg gtgacttggtatcgaaatggggtcaagattgaaagcaacaaaaaatacaccatcaataag aaaggcacaaaccacagtctaacgatcaaggagctggtcctgcaagatgcaggagagatt atggcagagtcagaagggatacagactaaggcatctctcaaggtccgagaaaaaccactg actttcaagaaaaagctggaagctatcactgtcgaggaaagacaaaccgtccggtttgaa gtcgaagtctctaaggccaccaaggaagtgaaatggatgaaaaacagcattgtcctgcag ccctctgagaacatagagatccagtctgaaggaactaagcagatccttatccttaagaat gtcacgtacactgaccgaggcctgtactgctgtgagaccctggatgacaagacacaggcc aagctcaatgtggaaatgcgtcaagtgaaagttgccaaagggctgaaggatgtagaagtc cacgagaaagatagtgccacttttgagttggagctgtcccatgaagatgtggaaggattt tggatgaaagacgggatcaaactgaaaccgtcagatacatgcaaaatgactttcaaggga aagaagcactctctaaccctgtcttctctgaagatggatgattcaggtcctgtggtattt aaatcagaaggactgcaatcttctgccaagctcactgttaaagaaccaccagtaaaaatc acactacctctgaaagacattaaagcaccggagaaggaaaaggtgacattcgaatgtgag gtgtctagacctaatgctgaagtgaaatggttcaaggatggttctgggttaaaaccaagc aaaaaagttgccattatttcacaagccaagaaaaggagtgtgacaattcacaagtgtgag cgtgaagaccaaggaacatatgtttgtgatgcaggagaagacaagacctctgcatacctg actgtacatggtcgagacatccagatcgttaaaccgcttgtggatgtggaagtggtagaa aaggagagtgcatcatttatgtgccagatttctcatgatgaggtgcaaacccagtggtat aaaaatggcatcaaactgaaagcaggagagaatgtaaagatgcgtcaagaaggaagaaca tattcattggttttccagagtgtccaggctgaggatgcagctgaaattaaatttgtggct gaagcatctgaatctcgggcaaaactaaaaataaaagaacttcccttaaaaattgtgaag cccctccgtgataagattgctatagagaagcacagggcattccttgagtgccaagtttca agagctagcgcagaagtgacttggtacaaaaagaacaagcagattgccccgggtgataaa tatgagattgtgagccaggggctgtacagaaaactcatcatcaatgaagcagagtttgag gatgaagatacctacacatgcgatgctggagatgacaagacttcagctaaacttctgatt gaagaacaatcaattaatattgtgaaggaactggcagatgtagaagtgacacagcctgaa tctgctacatttgaatgtgtcacatcgattgtgtcagtgaagcccccgaaatggtccctc ggtggagaagttctttgtgatggaaaaggcatcaccatagaacaagatggaaccgtccac cgactgacattgagaaagacttctcctgagatgtctggagctgtccagtttcacattgga aagtccaagtcttctgccaaacttttggttaaagaaatccccgttcggttaacccaacgt attgaggataagactgccaatgagcgccagactgtgatactgtcctgtgaatttaagcct cctcccaaatttgtggaatggtttaaagataaaagtcaaattgaaccatcagagaggttc aaactgaagctggagaggaacatggcagagctcaaaatattacaggtgactccagaggat tccggaacatatacctgcaaagctggagatgccgagacatcaggaaacctgaatgtacat gcccgtgatgtgaaagtcctgaagcccttgaaggatgtagaggttgaagaagaaagctgt gctgtgttctcctgtgagttgtcccacgatgatgaggaggtggaatggttcctgaacaac accctcctatactccaataatttcaatgacattcagaaaattggggccactcacactctt acgctgaaacaggtggcccccgaggactctggaacagtgagtgtgaagactaagaaactc tccttcagtgcacagctaaaggtcaaagaaaaaacagcagttttcatgaagtccttagat gatgctgtaggtgaggaacgaggaatggttactttagggtgtgaagtctccaaggccaag gtgaaaccagtctggaagaaagataaccaagtcctacccaatggagacaagtatcagcag atgcaggcaggaaaaaccgtgtgcttgatcatccatgaccttaacaagtctgatgcagga ctgtacatctgcgatattggaacagatactgcaaagtccaaaatcagtgttcaggagctc aacattggaatcactaagcgtctcaagagctcggaggctaaagaaggtgagagttgtacc tttgagtgcattctttctcacgagagcatcgatgaatgttcctggacagtgaatggacag agtgtagaaggtgaccaacgtttcaatgtctctaataagggacggaaatatgtacttcat ataaaagaagtgagagcaagagatgctggggaagtcatattcacagctcgaaatctgaac tccaaagcatcactgactattaaagaaaaaccatctgaaataataaaaccattggaagat aaaaccgttccagtgggagaagacgttattttgaagtgtgaactatctaaagaagacgca aatgtaaaatggtgcaaagatggaaaagtgctgaagaaaagccaaaaatatgaatttttc caggaaggaactgaaacccgaatgacaatccatgaagtcacgtcaaaagactctggagag tatacttgtgaaaccagcatctcccaaacaaaagccagcgtccaaataaaagaaaaaccc aactggttcaaaaaggaattgtcagatattaatattgaagaaggagagtctgcagttttt aactgtgagacagagaagaaggcatcctctgtaacctggagaaaagggataatggagatc aaatcaagtgaaaaatatgaaataagtcaaaaaggcaatgccctaagcttgcaggtcaat gacttggagaagagtgacagtgacctctatgtatgtgatattaaggacgcacagacgaag gccaacctcactgtcaaagccccacaagcctatttcaaacgggagctacagagcactgaa gctgtggaaggggaaacagccaccctgtggtgtgaactgtccaatcctgacgctgaggta gaatggagcaaagatggaaatgtgcttaaagccagcaagaagcatgaaatgcgagtgaga gaccacagggtggaactactgattcaccatttagtagaggaagatgctggaacctataaa tgtggaactggggaaaggacctcctcagcaactctaactgtgaaagttgagcaagttttg ttcaaacgagggctcaggaatgagaaagccaaagagggaggcagcgtgaagttgcactgt gaactgagcaaggcaagtgcgtctgttcgttggatgaagggcagccaagtcctagagaat ggagagaagtacaacatgaagctcgtcggcactgtggctgagctgtttattttgaatgca aagaccgaagattctggagactatacttgcgatattggagaccagaagagcacagccaat gtgacagtgactgccctgcccgttcgcttcaaacaagacctgaaagatgctgagattgaa gaaggctcctccgtgacgttatcttgtgaagtcactaagcctgacgccccagtcacgtgg aaaaagggcatcacaacccttcaagccaatgagaaatatgaatttaggcaaaaaggatgc ctagtagatttaattattcataaggcaggaccagaggattctggtacctacacttgtgat actggaaaccaacagacttctgcacgtgttaaagttaaggaactgccagcccttttcaaa gaagaacttaaacaccagaaggtctcagaaggtgaatgtgcttccctgcgctgcgagctc acaaaagccaatgcctccgttgaatggaagaaagatcacagaatgataaaacagagcaaa aagtataagatccgtcaggaaggtgcagtttccgagctagaaatacgtgacctggtattg gaggattcaggagattatagttgtgtgtgcggggaccacaagtctacagcaacagtgaca gtagctgcttccccaccgcgtttcagtgaggaactaagagatgagaaggccacggaaggc caacaggccactcttcattgtgagttaactaaacccggagctgtcttggaatggacgaaa ggtcaatcttttcttaaacctggtgggaaatattcaatgaggcaagaaggtctttctgct gagcttttaatcagcaatcttgaagaacgtgattcgggtgattacacatgcgtgtgcggg gatcagcagacgacagcaaccctaacagtgaatgctcttccggtattctttaaaaagaac ctgagggatacagtagctacagaagaagaaatggtcactcttcactgcgaactctccaaa ccagccacaaaggtggaatggaagaaaggtcaccggctgctgaagggaagtgacaagtat acaatgaaacttgaaggcttggctgctgagctgagtatcagtgacctaaacgtgaaagac agcggcgaatacacatgcgtttgtggagaccaggagaccacagcaaacctaacagttaat gctctgcctatccttttcaaagaagaactgagcaataaagaaagcccagaaggagaaaaa gttgctctatgctgtgtcttgacaaaagctcctggccatgttgagtggagacagggtcac aaagctctgaaatcaagtcccaaatatgaaatgagagtggatggggcttctgcagaacta ataatccataatttggaactgaaagacatgggagaatatacatgtgtgtgtggtgaacaa cagactacagctgtcttaatagtgaatgccttgcctactcacttcaaacatggactaaag gatgagaacataaaagagggcgaccgagctatcctgcactgcgagcttagcaaacccgat gtgactgtgcaatggagaaagaatagtgaggacttggtgacatctgaaaagcacatattg cgccaggatggttctattgcagaattggtgattcctcatctagaagaagaggattctggg gtttacacctgtatttgtggagatgtgaagaccacgtcaaccttaagcgttatagcttta cccccacgttttaaagaggaccttaaaaataaagaagcagttgaaggagactccgtcaca ctgcgctgtgagctgaccaagtctaatgcttctgtcgggtggaggagaggacaggaagcc ctcagacccaatgacaaatataagatgaggcaggaaggccttgtggctgagatacttata agtcagttagatctgcaggattctgggaaatacacttgtttttgtggagatcacgaaaca acagccatgctgactgtgaatgctgtgccaccacaatttaaagaggaactcaggagcaag gaagctgttgaagagagctcagttgtgttgacttgcaaactgacgaagcctaatgcacta ctagagtggaggagaggacacaagactctgaagacatgcgataagtacaaaatgatacag gaaggtcttgaggcagagttggtcattaataatttggacctgaaagatgccggcgagtat acttgtgtatgtggagttcaccagaccacagcttcactcactgtgaatgaattaccagcc ctctttaaagaagaaatcaaacatgcagaagaaagagaaggacagaaggctgtcttccat tgtaagctgactaagcctaatgcaagagtagagtggaagaaaggtcatgaaactcttcaa cctagtgataagcatcaactgatgcaggatggtgtcatagcggaactaaccatcagcaaa ctggagttaaaggattctgggaattatacatgtgtgtgtggagaggaggccactactgct tctttaacagttactgagctgcctgcagtcttcaatgctgatctgaaaaatgttgaggtc actgaaggggtaacagccacgttgcattgcggggtgacaaaggcttctgcatcagtacaa tggatgaaaggaaatcaagctttaagatccaatgataagtatcacatgaagcaagaaggt tgtgagattgagttgctaatatgtgatacggatctggatgatgctgaccagtacacctgc atctgtggagaccagaagacctctgctattttaactgtgaatgctctgcctgttgttttt aaagaagagctgaagaacacagaggtcacagaaagtgatacagcgactctccactgtgcc ctcagcaaacccaatgtttttgttgagtggaagaaaggaacccaagtgctgagtcagagt cagaaatattccttcagacaagaaggctcaagtgctgatcttgtaatcaacaacatagat ccaaaagatgcgggagaatacacgtgtacgtgtggcgataagaagacttcggctgtggtg acggtcaacgccctgccatgtgtattcacaaagcctctgcagaacactgaggctgaggag ggtgacacattgacgttgcgatgtgaagtgtctaagcctaatgtctcagtcgaatggaga aaaggaagcctaggccttcagcagggcagcaagtatgagatcaggcagaaggactgtgtt gcagaactgataatacacaacctcaggttggaagacacaggagagtacagctgtgatact ggggaccaggaaacaagggcctatctaacagtaaaagctctgccagtgctcttcaagaaa ccactaaaagacacaacagtagaggaaggtgtcaacgtgactcttcgctgtgaaaccaca aaaccaaatgtccccattgaatggaggaagggaaccattgggctcttcccatgtgctaaa tatgagatgagacaagaaggggttgcggctgaacttgtggtctatgacgttgaagcagga gatggggatgaatatacgtgtgatacaggagaccagcagaccaccgctaccatcaaagtc agtgtgctgcaattcttgcagaacttgcagaacatggaagctcaggaaggtgggaaagct cgattccgctgtgaggtatcttcaaagaagaatttagtggaatggagaaaaggagctcag acacttcaggcgagttccaagtatgaaatgaaagaacaagatggagtcagagaacttata atccacaatcttgagctggaagatgctggagagtacacctgtctgtcccggagcaagaaa tcttcagcaactcttaaagttaatgaactggatgtgactattgtgaagggcctgaaagac gtgtcagtatttgcagcagaagatgccgtgtttacgtgtgaactgtcccaccctgatgcc aaggatgtagagtggaagctgcaggggatcactctggcgaacaacgagatgaatgaaatt tcggtggagaagggcaagatccacaggctgaaactgagcagcgtgacacaggaggacaca ggcagtatcaccttcagggttggaccatacacatcaacagcagaacttaccgtgaaagcc ccacttccagtgtttaccaaaaatcttctggatatacaagtggaagaagatggctcagtt gtccttgaatgtgaactctcccagcccagtgtcccagtggtgtggaggaaaggcacagag cagatatctgccagtgcaaagtttgatatcaaggaactgggagctgttcactctttgcag atcaataacctcaaacctgaagactcaggcgtctatacatgtgatattggacatcaacag acaaaagcaaaagtaacagtcacagccctcccagtgcagataacaaaacctctgcagaac gagcagggagaagaaaacaaatatgttattctacgggctgaggtctctaaatcgaatgct ccaattcagtggaagaaagctggagttactcttcaaccaggttctaaatatgaaatgaag caggctggtcatgtggtagaacttcatatactcaaacttcagatgtctgatgctggagaa tatacctgtgatacaggggaccagaaatcagtggctaatgtctgtgttaaagagccagag ccgttcattattgaccatcttcagaacgtttctgtagaagagggggaagatgccatcttc aaatgtaaagtgtccaaggaaaatgccccagatgtacagtggtgcttagctggtgttcca ctgcagtccaatgaaatgaatgagatttcgtgccataaagggaaaattcacaccttaaca ctaaaaaaggtgtcaacacaagatactgggatcgtcagttttagagtagggcagaataca acgtcggcagagcttagcgttacagctgtagccttgacgtttaccaagaagcttcagcca gttgaaggagaggaacaaggagtggctgtgcttcaatgtgagatatccaaggtcaatgtt ccagtggaatggagaaagggatccaagattatcatacatggcgggcgatatgaaatcagc atgaatggatctgtccacaccttatgcattaaggacctcacctcggaggattctgaggaa tatagctgtagtgcccaaagtgaagcaacatcagccagactccaagtcaaccaactacct gtaacattcacccaagagcttcagaatgttgaaccagaggaaggaggcaccgcttcattg cagtgcaaagtatccagagccgatgcccatgtggaatggaggaagggagctcttgttcta caaaccagcgctaaatacgaaatgaagcaaagtggctccctcgttgaattgcttattcac aacgtggacctagaagactgtgggccctacacatgtagtactgacaccgcacaaacaaca gcctctgttttcgttcaagccaagaataaagtgctgcaagagctggagaacatcgatgcc gtagagggaggtgaagcactttttgagtgttacttgtctaagcctgagtgctacaactat aactggctgttagatgatgaacctgcgaggacatcagaaaacattgagatgatttatttt gaaaatggtcgtaggcatcttcttttactgaaaaacctcacctctcaagagagctgcaga gtaaccttcatagcgggcgctgctgtaacctcagcctttttgaatgtgcaaggatggcgc ttggaagttctgaagcctcctgtagacactgaagtcattgctggtggccaggcaaccttt agctgtatcctaagtgaagccattccagtaaatgaggttgcctggtattttaatggagta gatatccaaccagatgaaaactgggcaatgcaggtagatggaaatgagtacaagttaatt cttaaagacgctcaactacatcattcgggagaagtggcgtttgcttcaagagatgtagtg gcatcagccaagatttctgttcttgagcaccctatcaccataaaacaccaactggaaaac aaaaatctaaaggaaggtgaaactattcgccttgagtgtgaattctctaaagaaacccgg gacgtcaaatggatgaagggaagcgaaatactgacgtcggggggaaaatatgagtttgtt tgtcaaggacaaaaacaagttctgattattcataatagttcatcagatgatcagggctcc tacacatgtgcaacctcatcaggagacaaaacaaccgcctctgttactttggaaaaacaa ataatcaccgaagtcatgagcatacaagagatttttggtctagcacaagaaagaactgat atcaaacatgaagatgaagagagccagccaagtctcccaccagaggctgctcaagaaggg gatctccatttattatgggaagcattagcaaagaagcggagaatgagcagagaacctacg ctggattccatctctgagttgccagaagaagaagaaaagcgtaggcagaaaaaagaagca gaaaggcattcagacttttcagggtacacgtctgatgatttgactaaaacaagtgaagct gatttttcagtaacaagctcggacgatgaatcccgagctggaactccatctttggtgact tatcttaaaaaagctggccactctactgtcacacatagatccaaagtccacaaagtgtct gaaagcaaattttttaaacactttgagaccaaggaaattgagcgcaaggaaatcaaggaa cccccacaagaacctgagattccagatttatttcatgatgatgaccccgcactggataag gcggctgtgaaaattcaagctgcttttaaaggatacaaagcgagaaaggtgatcaagcaa caagaatgtcctttattcgcggaaacatttaaagatttatcggttgaaccaggaggaaca gtccatcttgaatgtgtagctatctgcaaaactgacattacagctcgatggttgaaagac aataaagaactctctgatggccggcattatcatattgataattaccctgatggaacctgt tccttgattattactgctgtagaaactgcagacactggcatatatacatgtgaagcctct aacaagtttggtgcagtttcacatagtgcttctttggtggttggcagtggtttacccgaa gttactctaaaaccaaagccgttgattgttaagtatggatcagacagtgaaacggagagt acaacaggaagtgatttggatgatgcttttagaaaggcaggaagaaggcttcataagatc tttaaatccaagacatcccttgaaatgtctgatgttgaagaagaactatttgttagtgct gatgagggtgacctaccacctgtagaccagcaaacctacagagaggatgataaatatatt tacatcaagtttgaagtcatgtcagaagcatcctttgctgctaaaagattcaaagagatg ttctctgcaatgggcatccctgtcaaaatagatattttggaccaaggtgcaaaaaatatt gacttacggataatgaaagtagagacaggaaccactgagcagcagagaatggcggcaaga catcaaatgaccttgttgacttctgatactgctcccatttttattactgaactacagaac caagaggtacaagatggttatccagtcagttttgattgtgttgttattggaagaccaatg ccatcagtacgttggttcaaagatggtaaggtgattgaagaggatgaccattacatgatc aatgaagaccaagagggatgccaccaacttattataactgccgtagtccccaaagacatg ggagtctacagatgtctggcagaaaatagaatgggggtatcttcaaccaaggctgagctg agagtggacttaaccagctcagattacgacacagcagaggcaacagaaacatcatcttat ttcagcgcacagggatatctgtccagggaacaggagggcctggaatctgccacagaacaa gaccagcttcctcagattctagaagagctacgagacacaatggttgccccagggactcca cttaccaaatttgagataaaagtgaaaggttacccaaggcctcgagtctactggtttaaa gatggtcaacccatccatgcctctgacagaatactaatgactgacaaaaagaaactgcat tcactggaaattctgaatgtgacaaaggaagacgctggggagtattcaacttacatcagt aattcagctggttctgcttactcatctgcaagactttctgtcaaagggccagatgagcta cagaaagacaagccaatggaagatgcagtagatggagagaagccagtaccaccaaggttc ttggaaagattcacaaacaaaaaagtattgaaaggagccagcataaccttgtctgtgaaa gttgaaggaattcctcctccaacaatcacctggttgaaggaagactctcctgaagatgta ctttggatcaaaccagacactcctgggtacaaaatggccagttcaaacaggcaccacagt ctgatcttactggatgttggcacagaattttctgggacttacacctgtattgcaacaaac aaggtggggcagtcgatctgcacagcctctgtggagattgcagaagctaaagaagccaag attctgaaagaagcagacaaattagtgaaagaaatgttgggtcgaacatcacttccaggg tttgaagagggcagggagacagaatctggagtgattggcatctccgtgcaaccgcctgag gatagtggagaggtgtccaagccccatatttcactgacagatgttgggacagaggaattc ttccagaaactgacatcccatattacagaaatggtgtctgcaaagataagtcaagcctca cttcgtgtccctggaacgacggggatggatagtgatgatgaaacgaagaccccttcagca tccccacgccacggaaggtccaggccttcctctattgctgttgagtcttcctcagagtca gaagatggcgactctagaggagagatatttgacatctacatggcgtctgcggattataac ccaattgtcgcagataaggaatccataaccttgaaagagggtcagtatgtggaggttcta gactctgcacatcccctcaaatggatggtccgaacgaagccaaccaagttcagtgcgtcc aggcaaggttgggtctcaccagcttacttggataagagactgaagctgtctactgagtgg actgcaggagaagcaccggaactttctggagtgtgtgtatcagaagaggagtacaagaag aagctcagcattctgatccaggagctgctaaacacagagaaggagtacgtgaaggagcta cagtttttggagaaccatcacctacatcacactgagcactggcccgatatcccagagagc gttgctagccaaaaatctaccatcttcaggaacatcagcgacattggcaattttcactca agcattttctttcctgagctgaagaaatgtgacacagacgatgacattgccatgtccttc ataaagaacgaggacgaattcaacaagtatatcatgttcctggttggccgcgtccaggcc gagtctgttgtactcagtgattctatccaggagttctacaagaactattcagaagaaaga ctggcactgtcagatccatccaagcccccagtgcctcctctgcaacattatctggaaatg cccataaacaggatccagagatatcaagtcattattaaggaactcatccggaacaaagca agaaatgggaagaattgtgcattgctggaacaggcctatgccattgtatctgctcttact cggcgggcagagaactttttgcatgtgtccatgatcgaaaactaccctggaacactagag gtcttgggtgaacctatccgtcagggtcatttcattgtttgggaaggagctccaggagct cgaatggcctggaagggtcacaaccgtcatgtatttctgttcaaaaactacttgatcatc tgcaaacccaagcgggacacaaagacagacacttatagctacgtgttcaagaacatgatg aagctgacaaatatagacatcaatgatcagatagaaggagacgacagagcttttgaggta tggcatgaacgggaagactcagtccggaaatacctgctgcaagctcgaaccgtcatcatt aaaaactcctgggtgaaggaaatctgtggcatacaagagcgctttagtatgccagtctgg aatcctccgaaattcatcgaaattttagcagactgcacagccgaattgggagaaactgtc aagctggcgtgccgtgtaacagggacacctaaaccagttgttgcctggtataaagatggc agacctgtggaagctgatccccatcacatcattattgaggaccctgatggctcctgcaca ttgattctggataacatgactggtgcggactcagggcagtacatgtgctttgcagccagc ccagccggaaacgccagcactttagggaagattcttgttcaagtgcccccaaggtttgtc aataagcttcgaaatgctcactttgtggatggtgaggattcccaattcacatgcaccatt gaaggagctccctacccacagataaggtggtacagagaagggaaactactgtcagaatct gctaaacaccagacattcactgaaccgagaagtggagtgttagtgctcgtggtcaagaat gcgaccaacgatgacctaggctattacgaatgtgagttggtgaacagactcggatcagct cgtagtggagcagaactgagcccaatgaccccggctctacttgcccaagaaaggagagga gaccagaccataactattgaagttaccgagcaggagactaaagtgcccaagaaaaccatc atcatagaggagacaataacgacagtggtgaaaagtccaagaatgaggcgcagacctgga ttttctccttcacgtcctgcctctgcatccccctcaaggcaaccaagatctgaaatgtca acacctgaaccccactttgtaaccagagccaaacagtttgttcataggcccgaacaagaa atcagaaagactgtgctcccaactctctttgtgacagaaccagaagatgagcgagggtca cattcaagagtggaagaacaaaagcccaggtactttgaagttgaggaaattattgaattt aaggtaaaaaaatctccgctgccacctagaaaaagaggaacatcgccagccaaaccagag aaagatgatttcagtggaaggaagtttacacgaccaagacgttcccctcatgatgatccc aacacaaacaactctaataacaaatcattggaagaatcaaactcttcactttcttcttgt ggtttatcggatactgatatcacgtcaatggattatggacttatagaggaggactcctat ttagatgataacttacatttacagtgtgtttcagaagaggacaatgactccttctcaaat gatatcactgctgccaatggatattctgctgtacagcacagaaatagtcctactcagaca gaaaccaaagtagaactaagtgtttcaaatgaaatagaaagttcagcattaggtacgaaa gaaaatgtttctgaattacaaaattcagagcaagagatgccctttgaagtagaagatgtc attgttgaagagccaccagaagaagaggaagacaatgagttgaaaaacagagataaaaaa attctcacttgcgatgggaaagttctaacatttgaggaccttgaagactatgttccaggc caaggagagacctatggatgtggtgaaaatgactcatatatatccaaagatgaaccatgc gaaatctctgtcttacaggctgaaattaatgagccaacaatcggcaagccagtgttgtta aatgtgggaagacctgtggtaccaaaaccaaggcaaagcttttttcacaactttaaagaa aacattactggaggaatatttatggcagcatcaaggatgagcagaatgaatttaatggga tcctcaaatgtttctttcagtatgaacgaaacctctatggctggggctagtgtgagttct ccatcgtctgcattgccttcattcaacattaaaccttcctactgcaccgaagtccaacgt tctgtagacaatggaccaccaagctttaaaacagaggtttctaccaggaccttgagctat ggaactcttggagaaactgtgacattgcatattagtaaaaaggatccttctaattgttaa

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