| Entry |
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| Symbol |
hspa5.S, BiP, grp78, hspa5, hspa5.L, XAP-1
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| Name |
(RefSeq) heat shock protein family A (Hsp70) member 5 S homeolog precursor
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| KO |
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| Organism |
xla Xenopus laevis (African clawed frog)
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| Pathway |
| xla04141 | Protein processing in endoplasmic reticulum |
| xla04156 | Integrated stress response (ISR) signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:xla00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
379756 (hspa5.S)
04141 Protein processing in endoplasmic reticulum
379756 (hspa5.S)
09140 Cellular Processes
09143 Cell growth and death
04156 Integrated stress response (ISR) signaling pathway
379756 (hspa5.S)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:xla03110]
379756 (hspa5.S)
04131 Membrane trafficking [BR:xla04131]
379756 (hspa5.S)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:xla04147]
379756 (hspa5.S)
Enzymes [BR:xla01000]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.10 non-chaperonin molecular chaperone ATPase
379756 (hspa5.S)
Chaperones and folding catalysts [BR:xla03110]
Heat shock proteins
HSP70 / DNAK
379756 (hspa5.S)
Membrane trafficking [BR:xla04131]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
379756 (hspa5.S)
Autophagy
ER-phagy
ER stress-related proteins
379756 (hspa5.S)
Exosome [BR:xla04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
379756 (hspa5.S)
Exosomal proteins of other body fluids (saliva and urine)
379756 (hspa5.S)
Exosomal proteins of colorectal cancer cells
379756 (hspa5.S)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
8S:40418638..40425439
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| AA seq |
655 aa
MVTMKLFALVLLVSASVFAADDDDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQG
NRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFK
VIEKKTKPYIQVNIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SAQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIVGKLYGGAGAPPPEGAEETEKDEL |
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| NT seq |
1968 nt +upstreamnt +downstreamnt
atggtgaccatgaagctgtttgccttggtgttgctggtgtctgccagcgtatttgctgct
gatgatgatgacaagaaagaagatgttgggactgtggttggaattgatttgggcacaaca
tactcctgtgttggagtgtttaaaaacgggcgtgtagaaattattgccaatgaccagggt
aaccgtatcacaccctcttatgtggcattcaccccagaaggtgagcgtctcattggagat
gctgcaaaaaaccaacttacatctaatcctgagaacactgtgttcgatgccaagcgtctg
attggtcgtacatggaatgacccctcagttcagcaggacataaagtacctgccttttaag
gtcattgagaagaaaacaaagccttacattcaagtcaatattggagatcagatgaaaaca
tttgccccagaagagatttctgctatggtgctggttaagatgaaggaaactgcagaggct
tacttgggcaaaaaggttactcatgctgttgtaactgtacctgcttatttcaatgatgca
cagcgtcaagccaccaaggatgcaggagttattgctgggctgaatgttatgaggatcatc
aatgaaccaactgctgcagctattgcttatggtctggacaaaagagaaggagagaagaac
atccttgtgtttgacttgggtggtggtacttttgatgtttccctacttacaattgataat
ggcgtatttgaagtggtggctacaaatggagatacccatcttggtggtgaagactttgac
cagagagtaatggagcatttcatcaagctgtacaagaagaaaactggcaaggatgtcaga
aaggataacagagctgtacagaaacttcgcagagaggtggagaaagccaagagggcattg
tcagcccagcatcaatctagaattgagattgagtctttctttgaaggagaagatttctct
gaaactctgacaagagccaagtttgaagagttgaatatggaccttttccgttccactatg
aagccagtacagaaagtccttgatgatgctgacctaaaaaaatctgacattgatgaaatt
gtgcttgttggtggctctactcgtatcccaaaaatccagcaattggtgaaagaattcttc
aatggcaaggagccttcccgtggtatcaatcccgatgaggctgttgcatatggtgcagct
gttcaagctggagtactttctggtgaccaggatactggtgacttggttctccttgatgtg
tgccctcttactcttggtattgagactgtcggaggtgtcatgacaaaactcattcccaga
aacactgttgtacccaccaaaaagtcacagatcttctctaccgcttctgacaaccagccc
actgtcactatcaaagtttatgaaggtgagcgtccactgaccaaggataaccatctcctg
ggcacttttgacttgactggaattccccctgcaccccgaggagttcctcagattgaggtc
acttttgaaatcgatgtgaatggtattctgcgtgttactgcagaggacaagggcactggc
aacaagaacaagattaccattacaaacgatcagaaccgtctaacacctgaggaaatcgag
aggatggtaactgatgcagagaaatttgcagaagaggacaaaaagttgaaggagcgtatt
gacactcggaatgaattggagagctatgcctactcattaaagaaccagataggtgataag
gagaagcttggaggaaaactttcttcagaagacaaggagaccattgagaaggctgtagaa
gaaaagatcgaatggttagaaagccaccaggatgctgatattgaagacttcaaggccaaa
aagaaggaattggaagaaattgttcaaccaattgtaggcaaactatatggtggagctggt
gcaccccctccagaaggtgccgaggagactgagaaggatgaattgtag |
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