Xenopus laevis (African clawed frog): 394427
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Entry
394427 CDS
T01010
Symbol
pole.L
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla03030
DNA replication
xla03410
Base excision repair
xla03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
394427 (pole.L)
03410 Base excision repair
394427 (pole.L)
03420 Nucleotide excision repair
394427 (pole.L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
xla03032
]
394427 (pole.L)
03400 DNA repair and recombination proteins [BR:
xla03400
]
394427 (pole.L)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
394427 (pole.L)
DNA replication proteins [BR:
xla03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
394427 (pole.L)
DNA repair and recombination proteins [BR:
xla03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
394427 (pole.L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
Motif
Other DBs
NCBI-GeneID:
394427
NCBI-ProteinID:
XP_018115858
Xenbase:
XB-GENE-1011592
UniProt:
A0A974E2Z8
A0A1L8HZP3
LinkDB
All DBs
Position
1L:complement(156116960..156168548)
Genome browser
AA seq
2285 aa
AA seq
DB search
MVLQNSGKFRAESRGDGQNQQDDASASSAAKRLERSQWTDKIDAQYGFERIREPGEKTGW
LLNMHPNEILDEDKRLVSAVDYYFIQEDGSRFKVALPYKPYFYVATKKGCEREVSSFLSK
KFQGKLAKSETIPKEDLDLPNHLVGLKRGYIKLSFHSVDDLIKVRKEISPAVRKNKERDH
ASDTYTAMLSSALTGNNMGAEEEGPSKKISDQMENIVDMREYDVPYHVRVSIDLKIHVAH
WYNIRYRGSSSPPEITRRDDLVERPDPVVMAFDIETTKLPLKFPDAETDQIMMISYMIDG
QGYLITNREIVSEDIEDFEFTPKPEYEGPFCIFNEADEAHLIQRWFEHIQETKPNIIVTY
NGDFFDWPFVETRATVHGMSMLQEIGFQKDNQGEYKSPPCIHMDCLRWVKRDSYLPVGSH
NLKAAAKAKLGYDPVELDPEEMCRMATEEPQVLATYSVSDAVATYYMYMKYVHPFIFALC
TIIPMEPDEVLRKGSGTLCEALLMVQAYHANIVFPNKQETVFNKLTNDGHVLDSETYVGG
HVEALESGVFRSDIPCRFKMNPAAFDFLLQRVELTLRHAIEEEEKIPLEQITNFQEVCDE
IKKKLNSLKEVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEVTCAACDFNKPGAA
CQRQMTWQWRGECMPASRSEYHRIQQQLESEKFPPLFPGKPPRAFHELTREEQAKYEKKR
LADYCRKAYKKIHVTRLEEKVTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSSA
SESGDAAEIKRCKNMEILYESLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCYTGANI
ITQARELVEQIGRPLELDTDGIWCVLPNSFPENFVIKSTNAKKPKVTITYPGAMLNILVK
EGFTNHQYQELSDPATLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNED
GSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYASVAKVADYWLDVLYSKAA
NMPDAELFELISENRSMSRRLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYVISR
KPEGSPVTERAIPLAIFQAEVGVKRHYLRKWLKNPSLQDLDIRSILDWDYYIERLGSAIQ
KIITIPAALQQVKNPVPRVRHPDWLHKKLLEKNDIYKQKRINELFTSEGKRQITAQMQQP
DSSQTPDMEDFGVGKRLQPAVPISTKRKRVPTAEESQGDSQDLALTQSWREVLGQPPPLG
TTKEERLVWLRYHKKKWELQARQRKERQKKRRLEDGEVAPGAGGVIRETQAAGLGSFLRR
TARSILDMPWQIVQIGESSQPGLFRLWAVIGNDLHCIKLNIPRLFYVNQRVPKPEEGAVY
RKVNRILPRSNPVYHLYEYTVPEDMYQEHINEINADLSAPDIEGVYETQVPLTMRAVSQL
GCVCMVNKQLVRHLSGREADTFDLDHLEMKSLAQYSYLEPGSIRHIYMYHNSQGHKALFG
LFIPSQRKSAVFVVDTVRSNQMPNLSNMYTAEHTAMQERVDPELLPPEKHIFEVRAETDL
KTVYRGIQRLLLSYKDERRGPTLIAVQSNWNARRLAAGMPVLDEFPLVPVRITDDISYGV
LDWQRHGARRMIRHYLNLDSCLSQAFEMARYYHLPVGNLPDDVSTFGSDLFFSRHLRRHN
HLLWLSPSARPDLGGKEADDNRLVMEFDERASVEINNPGCYNTVCVELDIQSLAVNSILQ
SHHINDLEGAGSMGISFDVLQQASLEDMVTGNQASSVASYDETALCSNTFRILKSMVVGW
VKEITQYHNVYADNQVMHFYRWLRSPSSLLYDPALHRTLHNMMKKLFLQLVAEFKRLGSS
VVYANFNRIILCTKKRRVEDAVAYVEYITQSIHSREIFHSLTISVSRCWEFLLWMDPANY
GGIKGKLPSSVHYGESAKKKKVQNGEEDDCSEEEEEEDQPVNSDDESEDQVEESLENNWN
IVQYLPQTASCQSYFLMIVSAYIVAVYHSMREEMRRNAPGNTPIKRRQNSQVSQETNGDG
GAMPGLITFSQDYVANELTQNFFTITQKIQKKVTGTRNATEPSEMFPSLPGSHLPLNNPA
LEFIKYVCEVLALDSNITNQVNKLKRDLLRLVDVGEFSEDAQFRDPCRSYILPEIICRSC
NFCRDLDLCKDPALNQDGSVLPQWVCTNCQAEYESDAIEMALVEALQKKMMAFTLQDLVC
LKCKGVKESNMPVYCSCAGDFALTISVKALLEQINVFRNIAQHYNMAHLLETIVWIMQQN
SHLIQ
NT seq
6858 nt
NT seq
+upstream
nt +downstream
nt
atggtgctccagaatagcggaaagttccgagctgagtcccgaggagatgggcagaatcag
caagatgatgcttctgcaagctcagctgccaagagattggaacgcagtcagtggacagac
aagattgatgctcagtatggatttgagaggattcgtgaaccaggggaaaaaacaggctgg
cttctcaacatgcacccaaatgagattttggatgaggacaaacggctggtgagtgctgtg
gattattacttcatccaagaagatgggagtagatttaaggtagcactgccgtacaaacca
tacttctatgtagctacaaagaagggctgtgagagggaggtttcctctttcctttccaaa
aagttccaggggaagctggcaaagtcggagacaataccaaaggaagacctcgatttgcca
aaccatcttgttggtctgaaacgtggctacattaaattgtctttccactcggtggatgac
cttattaaagtgaggaaggagatctcccctgctgtgaggaagaacaaagagcgagatcat
gccagtgacacttacacagccatgctctctagtgccctaactgggaataacatgggtgca
gaggaggaaggtccttccaagaagatctctgatcagatggagaatatagtggacatgcgg
gaatatgatgttccataccatgtgcgagtttctatagatcttaaaatacatgtggcacat
tggtataatattcggtatcgtggaagctcttcccctcctgaaattacacgacgagatgac
cttgtggaaaggcctgacccagttgtcatggcatttgacattgaaaccacaaagctgcct
ttgaagtttccagatgctgaaactgaccaaattatgatgatttcctacatgattgatgga
cagggttacctgataacaaacagggaaattgtatctgaagatattgaagactttgaattc
acaccaaagcctgagtatgaaggtcctttttgcatctttaatgaagcagatgaggcacat
cttatccagagatggtttgaacatatccaagagaccaaacccaatatcattgtaacatac
aatggggacttctttgactggccatttgtagaaactcgtgcaacagtgcatgggatgagt
atgcttcaggagattggctttcagaaagacaatcaaggggaatacaaatctcccccttgc
attcacatggattgtctcaggtgggtgaagagagatagttatctccctgttggaagccac
aatctcaaagctgctgctaaagctaagctgggttatgacccagtggagctggatccagag
gagatgtgtcgtatggctaccgaggaaccacaggtccttgccacttactctgtgtcagat
gcagtagcaacttactacatgtacatgaagtatgttcaccccttcatctttgcactctgc
actattattccaatggagcctgatgaggtcctgagaaaaggttcaggaaccctctgtgag
gcactgctgatggtccaagcataccatgcaaatattgttttccccaacaaacaagagact
gtattcaacaaattgactaatgatggccatgtgctggactctgagacctatgtaggtgga
catgtggaggcccttgagtctggagtgttcaggagtgacattccttgccgatttaaaatg
aacccagcagcctttgattttttactccagcgtgttgagttaactttgcgccatgcaatt
gaggaagaggaaaaaattccactggagcagataacaaactttcaagaggtctgtgatgag
attaagaagaaactcaattctcttaaggaggtgccaaacagaatagagtgtcctcttatt
taccatcttgatgtgggggcaatgtaccccaatattattctcaccaaccgacttcagccc
tctgccatggtggatgaagtgacttgtgctgcttgtgacttcaataaacccggtgctgct
tgtcagcgacagatgacttggcaatggagaggagagtgcatgcctgccagccgcagtgaa
tatcatcgcatacaacagcagcttgagtctgagaaatttccgcctctttttcctgggaaa
cctccacgagcttttcatgaattaacacgggaggagcaagcaaagtatgagaaaaaacgt
ttagcagattactgccgcaaagcatataaaaagatacatgtaacaaggctagaggagaaa
gtcacaaccatctgtcaaagggagaattccttctatgtggacactgtgcgagcttttcga
gatcgtagatatgagttcaaagggctgcacaaggtatggaaaaaaaagttatcttctgca
agtgaaagtggagatgctgctgaaattaagagatgtaagaacatggagattctttatgaa
tctctgcagctggctcacaagtgcattctgaattccttctatggatatgttatgcgcaaa
ggagcccgttggtattccatggagatggccggtattgtgtgctacactggagccaacatc
atcacacaagcccgagaactggtagaacagattgggagaccacttgaactagatacggat
gggatttggtgtgttcttccaaatagttttcctgaaaactttgtaatcaaatcaacaaat
gccaaaaagcctaaagtaaccataacgtacccaggggccatgctaaacattctggtgaag
gagggttttacaaaccaccagtaccaagagctgagtgacccagccaccctcacttatgta
acacgatctgagaatagtatcttctttgaagtagatggcccttatctggccatgatcctt
ccagcttccaaggaggaggggaaaaagctaaagaaaaggtatgctgtgtttaatgaggat
ggatcacttgctgagcttaaaggatttgaggttaagcgaagaggagagctgcagctgatc
aagatcttccagtcttctgtgtttgaggctttcctaaagggtagtacccttgaagaggtt
tatgcatctgtggcaaaggtggcagattactggctagatgtcctatacagcaaggcagcc
aatatgccagatgctgagttatttgagctaatctcagaaaatcgctccatgtcccgacga
ctggaagattatggagagcagaaatctacttccatcagtactgctaaaagacttgctgag
tttctgggagaccagatggtcaaggatgctggtctaagctgtcgctatgtcatctctcgc
aaacctgaaggctccccagtcacagagagagccattcccctggcaatatttcaggctgaa
gtgggcgtaaagaggcactacttgcgaaaatggctgaaaaatccttcattgcaggacctg
gatatacgctctattctagactgggattattacattgagagattgggcagtgcaatccag
aagatcattaccatcccagcagccctgcagcaggtgaagaatcctgttcctcgtgtacgt
catccagactggcttcataaaaagctgcttgaaaaaaacgacatctacaaacagaaacgt
ataaatgagctgttcaccagtgaaggcaaaagacagatcactgcccagatgcagcagcca
gattcctcacaaactccagacatggaagattttggagtaggcaaacgtctgcaaccagca
gtgccaataagcaccaaaagaaagcgtgtcccaacagctgaagagagccagggagactca
caagacctggctcttacccagtcttggcgggaagttttggggcagccacctcctctaggt
accacaaaggaagagcgtctagtctggcttcgttatcacaagaaaaagtgggagcttcag
gcacgccagcgaaaagagcgacagaaaaaacgaagactggaggatggagaagtggcacca
ggtgcagggggagtgataagagaaacgcaggcagctggacttggcagttttttaagacgg
actgcacgtagtattctagacatgccatggcagattgtgcaaataggtgagagcagtcaa
ccggggcttttccgcctgtgggctgttattggtaatgacctacactgcattaagctcaac
attccccgtcttttttatgtgaaccagcgcgtccctaaaccagaagagggagcagtgtac
cgcaaggtaaatcgaatcctacctcggtctaacccagtctaccatctttatgaatatact
gtaccagaggatatgtaccaagaacacatcaatgaaatcaatgcagacctgtctgccccc
gatattgagggggtgtatgaaacccaggttcctctcactatgcgagcagtaagtcagctt
ggctgtgtctgcatggtgaacaagcagctggtgcgacatctttcaggacgggaagcagac
acctttgacttagaccatttagaaatgaagtctcttgctcagtatagctacttggagcca
ggaagcatcagacacatctatatgtatcataattctcagggtcacaaagctctcttcggc
ctgtttatcccatcccagcggaaatcagctgtttttgtggtggacacggtccgcagtaac
cagatgccaaacctaagcaatatgtatacagcagaacacactgccatgcaggaaagagtg
gaccctgagcttctgcccccagagaaacacatttttgaggtacgagcagagacggacctg
aaaaccgtctacagaggaattcagagactactcctaagttacaaggatgaacggcgtggc
cccactctgattgcagtgcagtctaattggaatgcaagaaggttagcagctggaatgcct
gttctggacgaatttcctcttgttcctgtacgtataacagatgatattagctatggagtg
ttagattggcaacgccatggagccagacgcatgatccgtcattatctgaacctggatagc
tgtctttcccaggcctttgagatggcaaggtattatcacttacctgtgggtaacctacca
gatgatgtgtcaacctttggatctgacttgttcttctcaagacaccttcgtagacacaat
catctgctttggctgtcacctagtgcccgtcctgacctggggggcaaagaagcagatgat
aaccgtttggttatggagtttgatgagagggcatcagtggagattaataatccaggctgc
tataatactgtgtgtgttgagctggatatccagagtctggcagtaaatagtatccttcag
tcccatcatattaatgacctggagggagctggaagtatgggaataagctttgacgtcttg
cagcaagcctctcttgaagatatggtcactggaaaccaagcaagctctgtggccagctat
gatgaaacagccctctgttctaatactttcaggattctgaaaagcatggtggtgggctgg
gtaaaggagatcacacagtatcacaacgtctatgcagataaccaagttatgcatttttat
cgctggctgcggagtccatcctctctgttatacgatccagctttgcatcgaactctgcac
aacatgatgaagaagctattcttacaacttgtagcagaattcaagcgcctgggatcctct
gttgtttatgccaactttaaccgaattatcctgtgcacaaagaagcgccgagttgaagat
gcggttgcctatgtagaatacattacacagagcatccattctcgggagatctttcactct
cttacaatctcagtgtcacgttgctgggagtttctgctttggatggatccagcaaattat
gggggcatcaaaggaaagcttccttccagcgttcattatggagagagtgcaaagaagaaa
aaagtgcagaatggtgaagaggatgactgcagtgaggaggaagaggaagaagatcaacca
gtgaattcagatgatgagtccgaagatcaagttgaagaatcacttgaaaacaattggaat
attgttcaatacctgcctcagacagcatcttgtcaaagctacttcttgatgatagtttct
gcttacatagtggcagtgtatcacagtatgcgagaggagatgagacggaatgccccaggc
aacactccaattaaacgcagacagaacagtcaggtctcccaagaaactaatggagatgga
ggcgccatgccaggactcatcacattttctcaagattacgttgctaacgaacttacacaa
aacttcttcaccatcacacagaagatacagaagaaagtaactggaacccgtaatgccaca
gaaccctctgaaatgtttcccagtttaccagggtcacatctgccccttaataaccctgcc
ttggagttcataaaatatgtatgcgaggtactggcattggattcaaatatcacaaaccaa
gtgaacaagctgaagagagatctccttaggctagttgatgttggagaattctcagaagat
gcacagttccgtgatccatgccgttcttatatcttacctgagatcatatgcaggagttgt
aatttctgccgggatctagatttatgcaaggatcctgctttaaatcaggatggatctgtg
ctacctcagtgggtttgtacaaactgccaggctgaatatgaatctgatgctattgagatg
gctttggtagaagctctacagaaaaaaatgatggcttttacccttcaagatttggtgtgc
ttgaagtgtaaaggtgtgaaagaatccaacatgccggtgtattgcagctgtgcaggagac
tttgctctcacaatttctgttaaggcacttttggagcagattaatgtatttaggaatatt
gcacaacattacaacatggctcatcttctggagacaattgtttggattatgcaacaaaat
tctcatctaatccagtga
DBGET
integrated database retrieval system
