KEGG   Xenopus laevis (African clawed frog): 397692
Entry
397692            CDS       T01010                                 
Symbol
plcb3.L, plc-xb, plc1, plcb3
Name
(RefSeq) phospholipase C beta 3 L homeolog
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla00562  Inositol phosphate metabolism
xla01100  Metabolic pathways
xla04020  Calcium signaling pathway
xla04070  Phosphatidylinositol signaling system
xla04081  Hormone signaling
xla04082  Neuroactive ligand signaling
xla04261  Adrenergic signaling in cardiomyocytes
xla04270  Vascular smooth muscle contraction
xla04310  Wnt signaling pathway
xla04371  Apelin signaling pathway
xla04540  Gap junction
xla04621  NOD-like receptor signaling pathway
xla04912  GnRH signaling pathway
xla04916  Melanogenesis
Module
xla_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:xla00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    397692 (plcb3.L)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    397692 (plcb3.L)
   04371 Apelin signaling pathway
    397692 (plcb3.L)
   04020 Calcium signaling pathway
    397692 (plcb3.L)
   04070 Phosphatidylinositol signaling system
    397692 (plcb3.L)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    397692 (plcb3.L)
   04081 Hormone signaling
    397692 (plcb3.L)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    397692 (plcb3.L)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    397692 (plcb3.L)
  09152 Endocrine system
   04912 GnRH signaling pathway
    397692 (plcb3.L)
   04916 Melanogenesis
    397692 (plcb3.L)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    397692 (plcb3.L)
   04270 Vascular smooth muscle contraction
    397692 (plcb3.L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:xla04131]
    397692 (plcb3.L)
Enzymes [BR:xla01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     397692 (plcb3.L)
Membrane trafficking [BR:xla04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    397692 (plcb3.L)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    397692 (plcb3.L)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 397692
NCBI-ProteinID: NP_001081169
Xenbase: XB-GENE-1008416
UniProt: Q92137 A0A1L8GJS2
LinkDB
Position
4L:complement(26272239..26383232)
AA seq 1210 aa
MAGARPGVHSLQLEPVKVPETLIKGSKFIKWDEESSSKSLVTLRVDTMGFYLYWTCPNME
VDILDISVIRDTRTGKYAKIPKDTKMREILGFTGPEQRPEDKLVTVVYGNDIVNISFLNF
MAVQEDTAKIWTEELFKLAHNILAQNSSRNTFLQKAYTKLKLQVNQDGRIPVKNILKMFA
ADKKRVETALESCGLNFNRGDSIKPEEFTLDIFERFLNKLCLRPDIDKILLELGAKGKPY
LTLEQLMDFLNQKQRDPRLNEILFPPLKRDQVRQLIEKYEPNRQFLDRDQMSMEGFSRFL
GGHENSIVPPEILDLSDDMNQPLSSYFINSSHNTYLTAGQLTGNSSVEMYRQVLLTGCRC
IELDCWKGRPQDEEPFITHGFTMTTEIPFKEVIEAIAESAFKTSPFPVILSFENHVDSSK
QQAKMAEYCRNIFGDALLIDPLEKYPLQPGVALPSPQELMGKILVKNKKRHKVAVKGPEG
SVKRRVSEQTSNTYSDSSSVCESSATGLPPSESADVSLTLSNGDEKIEEKPPKYTEPRKS
IDHDAYSEEEEEEEPSDPKKSDEGTASSEVNATEEMSTLVNYVEPVKFKSFDAAKKRNKY
YEMSSFVETKALEQLTKSPMEFVEYNKKQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVAL
NFQTLDLPMQLNVGIFEYNRRSGYLLKPEFMCRTDKHFDPFTENIVDGIVANTVKIKIIS
GQFLSEKRVGIFVEVDMFGLPVDTKRKFRTKTSQGNSFNPVWDEEPFILPKVVLPTLATL
RIAVFEEGGKFVGHRILPVSAIRPGYHYICLRNELNQPVCLPALLVYTEVNDYIPDDHQG
YANALTNPIKHISLMDQRAKQLAALMGENEQPFNKDKIDWDPISKPPIRSRDDTPEKIKI
PIIPVPSPPAQRDDHIASVLTDIQAPTMEELKSQKSFEKLICRQYRELRQLRRKHLRKVS
SLCKEQSTWVTPLQSLRRRKPFGRSHRGVSGADQDAEQKLMDMQRDQQKRLLELREIQHE
QERKLKHSHLLQAVQKLQEVAISYHSTQLKKLKEINEKEKKELQKILDRKRHNSITEAKS
RERQKKDVELTEINRRHINESVSSIRRLEEAQKRRQEKLQTAHQETLQRIKDEEPKLQAQ
LDEACQAEFCQLPQEVRRYLQEDGWVGSGSGPPSSSHSSPPSITRSWGSESGEKDSLHSP
GDSSDEATRL
NT seq 3633 nt   +upstreamnt  +downstreamnt
atggcgggggcacggcctggggttcactctcttcaactggagcccgtgaaagtgccggag
actcttatcaaagggagcaagttcatcaagtgggatgaggagtccagcagcaaatccctg
gttactctgcgtgtggatacaatggggttttatctttactggacctgtccaaatatggag
gttgatattttggatatcagcgtaataagagacacccggacaggaaaatatgcgaaaatt
ccaaaggatacaaaaatgagggagattttgggattcacaggcccagagcagcgccctgag
gataagcttgttacagtggtatatggcaatgatattgtgaatatcagcttcctcaacttt
atggctgtgcaagaagatacagcaaagatttggacagaagagctttttaaattggcacat
aatattctggcacagaactcatctcggaacaccttcctgcagaaagcatacaccaaacta
aagctgcaagtgaatcaagatggacgaattccagttaagaatatcctaaagatgtttgca
gctgataagaaaagagtggaaacagcactggaatcttgtggcttgaactttaacaggggg
gattctattaaaccagaggaatttacactagatattttcgaacgcttcctgaacaagctg
tgtctgcgtccagatattgataagatccttctagaacttggagccaaagggaagccatat
ctgactctggagcaactaatggacttcctaaatcagaaacaaagggacccccggctcaat
gagattcttttccctccactaaaaagagaccaagtgcggcagctcattgagaagtatgag
cccaacaggcagttcctggacagagaccagatgtcgatggaaggtttcagccgcttttta
ggtgggcatgagaacagcattgttcccccggagatccttgatctaagtgatgatatgaac
cagccgctcagcagctactttattaactcctcccataacacctacctcacagctggccag
ctaactggaaattcatcagtggagatgtacaggcaagtgctgttgactggctgccgctgt
attgagctagattgctggaagggtcgtccgcaggatgaagaaccattcataacccatgga
ttcactatgaccaccgaaattccttttaaggaagtaattgaagcaatagcagaaagtgcc
tttaaaacatcgccgttcccagtcattttgtcatttgaaaatcatgttgactcttcaaag
cagcaagcaaagatggccgagtactgcaggaacatcttcggagatgcgttgttaatagac
ccgctggagaagtatcctctccagcctggagttgcacttcctagtccccaggaacttatg
ggtaagatcctagtgaagaataaaaaaagacacaaagtggcagtaaaaggcccagaaggc
agtgtaaaaagaagggtcagcgaacaaacctccaatacttacagtgactcatccagtgtt
tgcgagtcttctgctacaggtctaccaccttcagaatcagctgatgtttcattgacactt
tccaatggggatgaaaaaatcgaggagaaaccccctaaatatacagagccacggaaatcg
attgatcatgatgcttatagtgaggaggaagaagaagaagagccgtcagatcccaagaaa
tctgatgagggtacagcaagtagtgaggtgaatgccacagaggagatgtccacacttgtg
aattatgtagaacctgttaagttcaagtcatttgatgcggccaaaaaaagaaataagtat
tatgagatgtcctcatttgttgaaaccaaggcattggagcagctcactaaatccccaatg
gaatttgtggaatataacaagaagcagctcagccgtatttacccaaaaggaactcgggta
gattcctcaaattacatgccccagctcttctggaatgcaggatgtcaaatggtggctttg
aactttcaaacgctggatcttccaatgcagctgaatgtgggcatttttgagtataataga
cgcagtggttacctcctcaaaccggaattcatgtgcaggacagacaagcattttgatcct
tttactgaaaatatcgtcgatggaattgtcgcaaatacggttaaaatcaagattatatca
gggcagttcctatctgaaaagcgagtaggcatattcgtagaggtcgatatgtttggtctg
ccagttgataccaagaggaaatttcgcacaaaaacatcccaaggaaactcatttaatcct
gtctgggatgaagagccatttattttgcctaaggttgtactccccacacttgccactctc
cgcattgctgtctttgaagaaggtggaaagtttgtaggtcatcgaatcctgcctgtctca
gctatccgaccaggatatcactacatttgccttagaaatgagcttaaccagcctgtctgt
ctcccagcgctgcttgtttacactgaagtaaatgattatattcctgatgaccaccagggc
tatgcgaatgccttaactaaccccatcaagcacatcagcctcatggaccaaagggcaaag
caactggcagctctaatgggagagaatgagcaaccattcaacaaagacaagattgattgg
gatccaatatcaaagcccccaataagatcccgcgatgataccccagagaagattaaaata
cccattattcctgtgccttccccaccagcgcaacgagatgaccacattgccagtgtgctg
acagacatacaagcccccaccatggaagagctgaaatctcaaaagagctttgagaaattg
atttgccgccagtaccgagaactgcgtcaactacgccgcaagcacctgcgcaaggtgtcg
tctctgtgcaaggagcagagcacttgggtgacacctctgcagagtcttcgcaggaggaag
ccatttggaagaagccatagaggagtgtctggggcagatcaggatgctgagcagaagtta
atggatatgcagcgggaccaacaaaaacgtctcctggaactaagggaaattcaacatgag
caggaacgcaaactgaaacacagccacttactgcaggctgttcagaagctccaggaagtg
gccatttcctatcattccactcaactcaagaagttaaaggaaatcaatgaaaaggagaag
aaagagctgcagaagatcctggacagaaaaagacataacagcattacagaggccaagtca
cgggagcggcagaaaaaggacgtggaactgacagaaattaacaggcggcacattaacgag
tccgtaagctccatacgaaggctggaagaggcccagaaaaggcgtcaggagaagctgcag
acggctcaccaggaaacattgcaaaggataaaggatgaggaaccaaagctgcaggcacag
ttagatgaagcatgccaggctgagttctgccagctaccccaagaagtccgccgttacctg
caggaagatggttgggttggaagtggttcaggtcccccctcatcttcgcacagcagccca
ccctcaatcacccggagctgggggtcggagtctggcgaaaaagattctcttcattccccg
ggagattcaagtgatgaagccaccaggctctga

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