Xenopus laevis (African clawed frog): 398892
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Entry
398892 CDS
T01010
Symbol
araf.L, a-raf, araf, araf-a, araf-b, araf1, pks2, rafa1
Name
(RefSeq) A-Raf proto-oncogene, serine/threonine kinase L homeolog
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla04010
MAPK signaling pathway
xla04012
ErbB signaling pathway
xla04068
FoxO signaling pathway
xla04270
Vascular smooth muscle contraction
xla04810
Regulation of actin cytoskeleton
xla04910
Insulin signaling pathway
xla04914
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
398892 (araf.L)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xla01001
]
398892 (araf.L)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
398892 (araf.L)
Protein kinases [BR:
xla01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
398892 (araf.L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
TUG-UBL1
STATB_N
Pkinase_fungal
Kdo
Motif
Other DBs
NCBI-GeneID:
398892
NCBI-ProteinID:
NP_001083376
Xenbase:
XB-GENE-5755836
UniProt:
Q6PA51
A0A974C5I3
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Position
8L:1085845..1102297
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AA seq
643 aa
AA seq
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MKRSHTPPGALVNGALHSLSRELGKGSAVMLSAAVLELPNPGARMPTQQVSSRGASVSEY
PHTDGKSGGTVKVYLPNQQRTVVNVRPGMTVYDSLDKALKVRGLSQECCAVYRLIQGRKA
LTDWETDITPLVGEELMVEVLADVPLSMHNFVRKTHFNLAFCDFCLKFLFHGFRCQTCGY
KFHQHCSSKVPTACVDMAKLPKPLTPLSYQDFQSYYEHPTVHTPLSPQPPSPRTQHPGSA
SFSFPGEGQPLQRHRSTSTPNVHIDSTTGPVDNSIIEEALRSAAVTPVDGPPKSAQPRGS
KSPQTKSPLEATRERKTSASDEKKKVKQLGYRDSSYYWEVNSSEVIILKRIGTGSFGTVY
RGKWHGDVAVKILKVTNPTSEQIQAFKNEMQVLRKTRHVNILLFMGFMTRPQFAIITQWC
EGSSLYRHLHVIETRFDIFQLIDIARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKI
GDFGLATVKTRWSGSQQVEQPSGSILWMAPEVIRMQENSPYSFQSDVYAYGVVLYELMAG
LLPYANINNRDQIIFMVGRGYLTPDLSKVSNNCPKAMKRLLVDCMKFKREERPLFPQILS
SIELLQRALPKIERSASEPSLHRAVNSEDLNPFLISTLRLVPQ
NT seq
1932 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgctctcacacacctcctggtgcactagtaaatggtgccttgcactctctctcc
cgtgagctgggtaagggcagtgctgttatgttgtctgccgctgtcctggagctgcccaac
cctggtgcccggatgcccacccagcaagtaagctcccggggagcctcagtcagcgaatac
ccacacacagacggcaagtctggggggacagtcaaagtttatcttcccaaccagcagagg
acagtggtgaacgtgcgccctggtatgaccgtatatgattctctggacaaggcattgaaa
gtgcgaggtctgagccaggaatgttgtgctgtgtatcgcctgatacagggccggaaagcc
ctgacagattgggagacagatatcacacccctagtgggagaggagctgatggtggaggtt
ctggcagatgttcctttatccatgcacaattttgtcagaaaaacacatttcaacctcgca
ttttgtgacttctgccttaaatttctgttccacggcttccgctgccagacctgcggctac
aagtttcaccagcactgcagcagtaaggtgcccacagcctgcgtggatatggccaagctc
ccaaagccactgacgcctctcagctatcaagacttccagtcatattatgaacatcccact
gtccacacgcccctcagtccccagccacccagcccccggacacagcaccccggatccgct
tccttttcatttcctggtgagggacagccactgcagagacatcgctccacctccaccccc
aacgttcatattgacagcaccactggccccgtggataactccatcattgaggaggcgctg
agaagtgcagcagtcacacctgtcgatggtccccctaagagtgcccagcctcgtggaagt
aaatctccccaaactaagtcaccattagaggcaacacgagagaggaagacgtctgcgtct
gatgagaagaagaaagtgaaacagcttggttaccgagactccagttattactgggaggtg
aattccagcgaggtgattatcctgaagcgcattggcacaggctcctttggcaccgtgtac
cgagggaaatggcacggagacgtggctgtgaagatcctgaaagtgaccaaccccacatcg
gagcagattcaggcctttaagaacgagatgcaggttctcaggaagactcggcatgtcaat
attctgctgttcatgggcttcatgactcgacctcagtttgccattattacccaatggtgc
gagggaagcagtttgtaccggcacctgcatgtcattgaaacgcgcttcgatattttccag
ctgatcgacattgcccggcaaacggcacaaggcatggactatctccatgccaagaatatt
atccaccgggacttgaagtcaaacaacattttcctgcatgagggactgacggtgaagatt
ggtgactttggcttggccacagtgaagacccgttggagtggatctcagcaggtggagcag
ccgagtggatctattctgtggatggctccagaggtgattaggatgcaagagaacagcccc
tacagcttccagtcagatgtatatgcctacggggtggttctgtatgaactcatggctgga
ctgttaccctatgcaaatatcaacaacagagatcagatcatttttatggtgggacgcggt
tacctcactcctgacctcagcaaggtgtccaacaattgtcccaaggcaatgaagaggctt
cttgtagactgcatgaaattcaagcgagaagagaggccccttttcccacagatcctctcc
tccattgagcttctgcagcgagctctgcctaaaatagagcgcagtgcgtccgaaccttcc
ctgcaccgggctgtcaactccgaggacctcaaccccttcctcataagcaccctccgactc
gtgcctcagtga
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