Xenopus laevis (African clawed frog): 432200
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Entry
432200 CDS
T01010
Symbol
ikbkb.L, ikbkb, ikk-beta, ikk2, ikkb, ikkbeta
Name
(RefSeq) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog
KO
K07209
inhibitor of nuclear factor kappa-B kinase subunit beta [EC:
2.7.11.10
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla04010
MAPK signaling pathway
xla04068
FoxO signaling pathway
xla04150
mTOR signaling pathway
xla04210
Apoptosis
xla04620
Toll-like receptor signaling pathway
xla04621
NOD-like receptor signaling pathway
xla04622
RIG-I-like receptor signaling pathway
xla04623
Cytosolic DNA-sensing pathway
xla04625
C-type lectin receptor signaling pathway
xla04910
Insulin signaling pathway
xla04920
Adipocytokine signaling pathway
xla05132
Salmonella infection
xla05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
432200 (ikbkb.L)
04150 mTOR signaling pathway
432200 (ikbkb.L)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
432200 (ikbkb.L)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xla01001
]
432200 (ikbkb.L)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
432200 (ikbkb.L)
Protein kinases [BR:
xla01001
]
Serine/threonine kinases: Other
IKK family [OT]
432200 (ikbkb.L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
IKBKB_SDD
Pkinase
PK_Tyr_Ser-Thr
IKKbetaNEMObind
Pkinase_fungal
Kdo
ubiquitin
YrbL-PhoP_reg
APH
Motif
Other DBs
NCBI-GeneID:
432200
NCBI-ProteinID:
NP_001085125
Xenbase:
XB-GENE-949882
UniProt:
Q6INT1
Structure
PDB
PDBj
LinkDB
All DBs
Position
3L:139923634..139954581
Genome browser
AA seq
742 aa
AA seq
DB search
MKERLGTGGFGYVLRWIHQDTGEQVAIKQCRQELSPKNRERWCLEIQIMKKLNHPNVVSA
REVPDGLQKLAPNDLPLLAMEYCEGGDLRKYLNQFENCCGLKEGPIRTLLSDISSALRYL
HENRIIHRDLKPENIVLQPGPQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQ
KKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHGKVREKSNEHIVVYDDLTGAVKFS
SVLPTPNHLSGILAGKLERWLQCMLMWHQRQRGTDPQNPNVGCFQALDSILSLKLLSVMN
MVSGRVHTYPVTENENLQNLKSWLQQDTGIPEEEQELLQASGLALNSAQPLTQYVIDCTV
IDGRQGEGDLIFLFDNRKTVYEPQISLPAHPESVSIVLQDPKRPLTYTHLRRVWGQIWQT
IRALKEDCARLLQGQRTSMVNLLRYNTELSKKKNSMTSECEQLKAKLDFFRSSIQIDLEK
YSEQMEFGITSEKLLSAWREMEQAVELCGREREVQALVDKMMALQTDSVDLQRNPLGRKH
RGTLDDLEEQARDLYRRLRERPRDQRTPGDSNDMVRLLILAIQSFEKRVILIYDQLSKTV
VCKRKALELSPKVKEVMNLMREDEKIVVRRQEKRQQELWNLLKIACSKVRGPVSGSPDSL
GTSRMPGPSQLLSQPPVLSVSLAQEYVKKSEDLRSESLNLCSQLESSMRSFMKEQDGSLM
SLDWSWLLQQEEESGASPITTS
NT seq
2229 nt
NT seq
+upstream
nt +downstream
nt
atgaaggaacgattgggaacgggaggatttggttatgtcctgcgctggattcaccaggat
acaggagagcaggtggctataaagcagtgccgacaggagctgagccctaagaaccgggag
agatggtgtctggaaatccagatcatgaaaaagttaaatcatcccaatgtagtctctgcc
cgtgaagttcctgatgggctacagaagctggcccccaatgacctcccccttctggctatg
gaatactgtgaggggggtgacctgcgcaagtatctgaatcagtttgagaattgctgtggc
cttaaggaaggaccgatacggactctgctcagtgacatttcctccgcgcttcgatacctc
cacgagaacagaatcatccacagagatctgaagcctgagaacattgttctgcagccagga
ccacagagattgatccataaaattattgatttgggatatgccaaggagcttgatcagggt
agtctgtgcacatccttcgtgggtaccctacagtatttggccccagaattgctggagcag
aagaagtacaccgtgactgttgattactggagtttcggaaccttggcctttgaatgtata
acaggattccgacctttccttccaaactggcaaccagttcaatggcatgggaaagtgcga
gaaaaaagcaatgagcacattgtggtatatgatgacctgaccggagctgtgaagttctcc
agtgttttaccaactcccaatcatcttagtggcatactggctggcaagttggagcgatgg
ctacagtgtatgttaatgtggcaccagaggcagagaggcacagatccccagaaccctaat
gtgggttgcttccaggccttggattccatcctaagccttaagctgctgtccgtaatgaac
atggtgtctggccgtgtgcacacttacccagtgaccgagaatgaaaacctgcagaatctg
aagagttggctgcagcaagacacagggattcccgaggaagagcaggaactattgcaggcc
tcaggactggcccttaattctgcccagcctctaacccaatatgtgatagactgcacggtt
attgatgggcgtcagggtgagggtgatctgatatttctttttgataaccggaagactgta
tacgaacctcagatatcactgccggcacaccctgagagtgtctccattgtattgcaggat
cccaagcggcccctcacttacacccacctccgacgtgtgtgggggcagatctggcagaca
atacgagcactgaaagaggattgtgctcgtctccttcaagggcaacgtacctctatggta
aacctgctgcgatacaataccgaactttcaaaaaaaaagaactcaatgacctctgagtgt
gagcagctaaaggccaaactggatttcttccggagcagtatccagattgatctagaaaaa
tacagcgaacagatggagtttggaatcacttctgaaaagctcctgtcagcctggagagag
atggagcaagcagtggaattgtgtggaagggaaagggaagtgcaagctcttgtggataaa
atgatggctttacaaacggacagtgtagatctgcagagaaatccactaggcaggaaacat
cgggggaccctggatgacctagaagagcaggctagagacctatatcggcggctacgagag
cgacctagagatcagaggacgccaggtgacagcaacgacatggtgcgcctcctaatacta
gccatccagagcttcgagaagagagtcatccttatatacgaccaactcagcaagactgtg
gtgtgcaagcgcaaagctctggaactctccccaaaggtgaaagaggtgatgaacctaatg
cgagaggatgaaaagatagtggtgaggagacaagagaagagacagcaggagctctggaac
ctgctaaagattgcttgtagcaaagtccgcggccctgtgagtggtagcccagatagcttg
ggcacatctcgaatgcctggccccagccaactgctttcccagcctcctgtcctctccgtc
agcctagcccaagagtatgtgaagaaaagtgaagatcttcggtcggaatctttgaatctg
tgtagccaactggaatcttcaatgaggagctttatgaaggaacaagatggtagtctaatg
tctttagattggtcgtggctgttgcagcaagaggaggagtcgggcgcatctcccatcaca
acctcgtga
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