Xenopus laevis (African clawed frog): 432200
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Entry
432200 CDS
T01010
Symbol
ikbkb.L, ikbkb, ikk-beta, ikk2, ikkb, ikkbeta
Name
(RefSeq) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog
KO
K07209
inhibitor of nuclear factor kappa-B kinase subunit beta [EC:
2.7.11.10
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla04010
MAPK signaling pathway
xla04068
FoxO signaling pathway
xla04150
mTOR signaling pathway
xla04210
Apoptosis
xla04519
Cadherin signaling
xla04620
Toll-like receptor signaling pathway
xla04621
NOD-like receptor signaling pathway
xla04622
RIG-I-like receptor signaling pathway
xla04623
Cytosolic DNA-sensing pathway
xla04625
C-type lectin receptor signaling pathway
xla04910
Insulin signaling pathway
xla04920
Adipocytokine signaling pathway
xla05132
Salmonella infection
xla05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
432200 (ikbkb.L)
04068 FoxO signaling pathway
432200 (ikbkb.L)
04150 mTOR signaling pathway
432200 (ikbkb.L)
09133 Signaling molecules and interaction
04519 Cadherin signaling
432200 (ikbkb.L)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
432200 (ikbkb.L)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
432200 (ikbkb.L)
04621 NOD-like receptor signaling pathway
432200 (ikbkb.L)
04622 RIG-I-like receptor signaling pathway
432200 (ikbkb.L)
04623 Cytosolic DNA-sensing pathway
432200 (ikbkb.L)
04625 C-type lectin receptor signaling pathway
432200 (ikbkb.L)
09152 Endocrine system
04910 Insulin signaling pathway
432200 (ikbkb.L)
04920 Adipocytokine signaling pathway
432200 (ikbkb.L)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
432200 (ikbkb.L)
09171 Infectious disease: bacterial
05132 Salmonella infection
432200 (ikbkb.L)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xla01001
]
432200 (ikbkb.L)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
432200 (ikbkb.L)
Protein kinases [BR:
xla01001
]
Serine/threonine kinases: Other
IKK family [OT]
432200 (ikbkb.L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IKBKB_SDD
Pkinase
PK_Tyr_Ser-Thr
UBL_IKK
IKKbetaNEMObind
Pkinase_fungal
Kdo
ubiquitin
APH
YrbL-PhoP_reg
Spectrin_SYNE1_2
Motif
Other DBs
NCBI-GeneID:
432200
NCBI-ProteinID:
NP_001085125
Xenbase:
XB-GENE-949882
UniProt:
Q6INT1
Structure
PDB
PDBj
LinkDB
All DBs
Position
3L:139923634..139954581
Genome browser
AA seq
742 aa
AA seq
DB search
MKERLGTGGFGYVLRWIHQDTGEQVAIKQCRQELSPKNRERWCLEIQIMKKLNHPNVVSA
REVPDGLQKLAPNDLPLLAMEYCEGGDLRKYLNQFENCCGLKEGPIRTLLSDISSALRYL
HENRIIHRDLKPENIVLQPGPQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQ
KKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHGKVREKSNEHIVVYDDLTGAVKFS
SVLPTPNHLSGILAGKLERWLQCMLMWHQRQRGTDPQNPNVGCFQALDSILSLKLLSVMN
MVSGRVHTYPVTENENLQNLKSWLQQDTGIPEEEQELLQASGLALNSAQPLTQYVIDCTV
IDGRQGEGDLIFLFDNRKTVYEPQISLPAHPESVSIVLQDPKRPLTYTHLRRVWGQIWQT
IRALKEDCARLLQGQRTSMVNLLRYNTELSKKKNSMTSECEQLKAKLDFFRSSIQIDLEK
YSEQMEFGITSEKLLSAWREMEQAVELCGREREVQALVDKMMALQTDSVDLQRNPLGRKH
RGTLDDLEEQARDLYRRLRERPRDQRTPGDSNDMVRLLILAIQSFEKRVILIYDQLSKTV
VCKRKALELSPKVKEVMNLMREDEKIVVRRQEKRQQELWNLLKIACSKVRGPVSGSPDSL
GTSRMPGPSQLLSQPPVLSVSLAQEYVKKSEDLRSESLNLCSQLESSMRSFMKEQDGSLM
SLDWSWLLQQEEESGASPITTS
NT seq
2229 nt
NT seq
+upstream
nt +downstream
nt
atgaaggaacgattgggaacgggaggatttggttatgtcctgcgctggattcaccaggat
acaggagagcaggtggctataaagcagtgccgacaggagctgagccctaagaaccgggag
agatggtgtctggaaatccagatcatgaaaaagttaaatcatcccaatgtagtctctgcc
cgtgaagttcctgatgggctacagaagctggcccccaatgacctcccccttctggctatg
gaatactgtgaggggggtgacctgcgcaagtatctgaatcagtttgagaattgctgtggc
cttaaggaaggaccgatacggactctgctcagtgacatttcctccgcgcttcgatacctc
cacgagaacagaatcatccacagagatctgaagcctgagaacattgttctgcagccagga
ccacagagattgatccataaaattattgatttgggatatgccaaggagcttgatcagggt
agtctgtgcacatccttcgtgggtaccctacagtatttggccccagaattgctggagcag
aagaagtacaccgtgactgttgattactggagtttcggaaccttggcctttgaatgtata
acaggattccgacctttccttccaaactggcaaccagttcaatggcatgggaaagtgcga
gaaaaaagcaatgagcacattgtggtatatgatgacctgaccggagctgtgaagttctcc
agtgttttaccaactcccaatcatcttagtggcatactggctggcaagttggagcgatgg
ctacagtgtatgttaatgtggcaccagaggcagagaggcacagatccccagaaccctaat
gtgggttgcttccaggccttggattccatcctaagccttaagctgctgtccgtaatgaac
atggtgtctggccgtgtgcacacttacccagtgaccgagaatgaaaacctgcagaatctg
aagagttggctgcagcaagacacagggattcccgaggaagagcaggaactattgcaggcc
tcaggactggcccttaattctgcccagcctctaacccaatatgtgatagactgcacggtt
attgatgggcgtcagggtgagggtgatctgatatttctttttgataaccggaagactgta
tacgaacctcagatatcactgccggcacaccctgagagtgtctccattgtattgcaggat
cccaagcggcccctcacttacacccacctccgacgtgtgtgggggcagatctggcagaca
atacgagcactgaaagaggattgtgctcgtctccttcaagggcaacgtacctctatggta
aacctgctgcgatacaataccgaactttcaaaaaaaaagaactcaatgacctctgagtgt
gagcagctaaaggccaaactggatttcttccggagcagtatccagattgatctagaaaaa
tacagcgaacagatggagtttggaatcacttctgaaaagctcctgtcagcctggagagag
atggagcaagcagtggaattgtgtggaagggaaagggaagtgcaagctcttgtggataaa
atgatggctttacaaacggacagtgtagatctgcagagaaatccactaggcaggaaacat
cgggggaccctggatgacctagaagagcaggctagagacctatatcggcggctacgagag
cgacctagagatcagaggacgccaggtgacagcaacgacatggtgcgcctcctaatacta
gccatccagagcttcgagaagagagtcatccttatatacgaccaactcagcaagactgtg
gtgtgcaagcgcaaagctctggaactctccccaaaggtgaaagaggtgatgaacctaatg
cgagaggatgaaaagatagtggtgaggagacaagagaagagacagcaggagctctggaac
ctgctaaagattgcttgtagcaaagtccgcggccctgtgagtggtagcccagatagcttg
ggcacatctcgaatgcctggccccagccaactgctttcccagcctcctgtcctctccgtc
agcctagcccaagagtatgtgaagaaaagtgaagatcttcggtcggaatctttgaatctg
tgtagccaactggaatcttcaatgaggagctttatgaaggaacaagatggtagtctaatg
tctttagattggtcgtggctgttgcagcaagaggaggagtcgggcgcatctcccatcaca
acctcgtga
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