KEGG   Xenopus laevis (African clawed frog): 432317
Entry
432317            CDS       T01010                                 
Symbol
mthfd2.L, mthfd2, nmdmc
Name
(RefSeq) methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase L homeolog
  KO
K13403  methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla00670  One carbon pool by folate
xla01100  Metabolic pathways
xla01240  Biosynthesis of cofactors
Module
xla_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:xla00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    432317 (mthfd2.L)
Enzymes [BR:xla01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)
     432317 (mthfd2.L)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     432317 (mthfd2.L)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH CcmH AKAP_110 PirA-like
Other DBs
NCBI-GeneID: 432317
NCBI-ProteinID: NP_001085223
Xenbase: XB-GENE-941969
UniProt: Q2VPP2
LinkDB
Position
3L:128437908..128453611
AA seq 335 aa
MATITSLRVLCCAVRAQVRTIHCTPCRNEAVVISGRKLARQIRQEARHDVEQWVAAGNKR
PHLSVILVGDDPASHSYVLNKTKAAADVGISSETILKPTSITEEELLDLINKLNDDDHVD
GLLVQLPLPEHLDERNICNAVTPDKDVDGFHVVNVGRMCLDQYSMLPATPWGVWEIIKRT
GIPTLGKNVVVAGRSKNVGMPIAMLLHTDGRHERPGGDATVTISHRYTPKEQLKMHTKLA
DIVVAAAGIPNLITADMIKEGAAVIDVGINRVQDPVTGKPKLVGDVDFEGVRKKASYITP
VPGGVGPMTVAMLMKNTIIAAKKMLKPTELQAVAM
NT seq 1008 nt   +upstreamnt  +downstreamnt
atggcaacaattacatctctccgggttctgtgctgcgctgtgagagcccaggttcggacg
atccactgtaccccgtgcaggaatgaggcagtcgtcatctctggcagaaagctggcaagg
caaatccggcaagaggcccggcacgatgtggaacagtgggtggcagccggcaacaagagg
ccacacctcagtgtcattcttgttggagacgaccctgcgagccattcctacgtgttaaac
aagacaaaagccgctgcagacgtgggtatcagcagtgaaaccatactcaagccaacatcc
atcacagaagaggagctcttggacctcatcaacaagcttaatgacgacgatcatgtcgat
gggctccttgtgcagctgcctctcccagaacacttagatgagaggaatatctgcaacgct
gttactccagacaaagatgttgatggtttccatgtggtgaacgtgggccgaatgtgcctg
gaccagtactccatgctgccggccaccccttggggagtgtgggagatcattaaaagaaca
ggaattcccactcttggtaaaaacgtggtagtagctggaagatctaaaaatgttgggatg
cccattgcaatgctgctgcacacagatggacggcatgagcgtcctggaggtgatgcaaca
gtgacaatatctcaccgctacactcctaaggaacagctgaagatgcacaccaaacttgcc
gatattgttgttgcagctgcaggcatccctaacctcatcacggctgacatgataaaggaa
ggcgctgcagtcatcgatgttggcattaaccgcgtgcaggatccagtcaccggcaaacca
aaacttgttggtgatgtggattttgaaggtgtaagaaagaaagcaagttacatcactcca
gtgccagggggggtgggacctatgactgttgccatgctaatgaagaacacaatcattgct
gcaaagaaaatgttgaaacccacagagctccaagccgttgccatgtaa

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