KEGG   Xenopus laevis (African clawed frog): 444287
Entry
444287            CDS       T01010                                 
Symbol
cltc.L, Clathrin, cltc
Name
(RefSeq) clathrin, heavy chain (Hc) L homeolog
  KO
K04646  clathrin heavy chain
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla04142  Lysosome
xla04144  Endocytosis
xla05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:xla00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    444287 (cltc.L)
   04142 Lysosome
    444287 (cltc.L)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    444287 (cltc.L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:xla04131]
    444287 (cltc.L)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:xla04147]
    444287 (cltc.L)
Membrane trafficking [BR:xla04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Clathrin
    444287 (cltc.L)
Exosome [BR:xla04147]
 Exosomal proteins
  Proteins found in most exosomes
   444287 (cltc.L)
SSDB
Motif
Pfam: Clathrin Clathrin_propel Clathrin_H_link Clathrin-link TPR_COPA_B TPR_Vps41 TPR_1
Other DBs
NCBI-GeneID: 444287
NCBI-ProteinID: NP_001085860
Xenbase: XB-GENE-984052
UniProt: Q6GNR4 A0A974DPX7
LinkDB
Position
2L:94954789..95022690
AA seq 1675 aa
MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGDQAQVVIIDMNDASN
PIRRPISADNAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVSFWKWISLNTVA
LVTDNAVYHWSMEGESQPVKVFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGA
MQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGN
QPFPKKAVDVFFPPEAQNDFPVAMQISSKHDVVFLITKYGYIHLYDLETGTCIYMNRISG
ETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGA
EELFARKFNALFAQGNYSEAAKVAANAPKGILRTPETIRRFQSVPAQPGQTSPLLQYFGI
LLDQGQLNKFESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYL
RANVPNKVIQCFAETGQVQKIVLYAKKVGYTPEWIFLLRNVMRINPDQGQQFAQMLVQDE
EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPTEGPLQTRLLEMNLMHAPQVADAIL
GNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSV
EDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTLSLIELFESFKSFEGLFYFLGSIVN
FSQDPDVHFKYIQAACKTGQIKEVERISRESNCYDPERVKNFLKEAKLTDQLPLIIVCDR
FDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKSLILVVRGQF
STDELVAEVEKRNRLKLLLPWLESRIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYY
DSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWASVL
LESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSE
HRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTS
AVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSFMEV
VEAANASGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQ
VGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFAC
VDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTEL
AILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEFDNAIITMMN
HATDAWKEGQFKDIITKVANVELYYKAIHFYLEFKPLLLNDLLMVLSPRLDHTRAVNFFT
KVKQLPLVKPYLRSVQNHNNKSVNEALNNLFITEEDYQALRTSIDAYDNFDNISLAQRLE
KHELIEFRRIAAYLFKGNNRWKQSVELCKKDKLYKDAMQYASESKDTELAEELLQWFLVE
EKKECFAACLFTCYDLLRPDVVLETAWRHNIMEFAMPYFIQVMREYLSKVDKLDASESIR
KEEEQATETQPIVYGQPQLMLTAGPSVPVPPQAAYGYGYTAPAYGQPQPGFGYSM
NT seq 5028 nt   +upstreamnt  +downstreamnt
atggctcagatcctcccgatccgcttccaggagcacctgcagctccaaaatctgggtatt
aatccagccaacattggttttagtacccttacaatggagtctgataaattcatctgcatt
cgggagaaggtaggagaccaagcccaagtggttatcattgacatgaatgatgccagcaac
ccaattcgcaggcctatttcagctgacaatgccataatgaatccagccagcaaggtcatc
gctctgaaagctggaaaaacactccaaatttttaacattgaaatgaaaagcaagatgaag
gcccacaccatgaccgatgatgtctcattctggaaatggatctccttgaacactgtcgct
ttagtgactgacaatgcagtctatcattggagtatggagggggaatctcagccagtaaag
gtgtttgaccgacattcaagcctggcagggtgccagatcattaattatcgaacagatgca
aagcaaaagtggctgcttctcactggaatatctgcccagcaaaaccgggttgtgggagcc
atgcagctttactctgtagacaggaaagtgtctcagcccattgaaggacatgctgccagc
tttgcacagttcaagatggaaggaaatgctgaagaatcaaccctcttctgctttgctgta
aggggtcaagctgggggtaagctccatattatagaagttggtacaccacctacaggcaac
cagccatttccaaagaaagctgttgatgtcttctttcctccagaagctcagaatgatttt
cctgtagccatgcagattagcagtaagcacgatgttgtttttctgattacaaaatatggc
tacattcacctttatgacctagaaactggcacctgcatttatatgaatcgtataagtggg
gaaaccatctttgttactgcccctcatgaagccacagctggaatcatcggagttaacaga
aaaggacaggttctttctgtgtgtgtggaagaggagaacataatcccatatatcacaaac
gttctgcagaaccccgacctagctttgcgtatggctgtacgaaacaaccttgctggagct
gaggagctttttgctcgaaaattcaatgctctctttgcacaaggaaattattcagaagca
gcaaaggtggctgcaaatgccccaaagggaatactgcgtacaccggaaacgatccgccgt
ttccaaagtgttcctgcacaaccaggtcagacctccccattgctgcaatactttggaatt
cttttagaccaaggccagctgaacaagtttgaatcattggagctttgcagacctgtgttg
caacaaggtcgcaaacaactgttggaaaaatggcttaaggaagacaagctggagtgttcg
gaagaattgggagatctcgtaaagtctgttgaccctacacttgccttgagtgtttatctg
agggctaatgttccaaataaagtaattcagtgctttgcagagactggacaggttcagaag
attgtgctgtatgcaaaaaaggtgggctatacccctgaatggattttcctgctgcgaaat
gttatgcgaatcaatccagaccaaggccaacagttcgctcaaatgttggtccaagatgag
gagcctcttgcggatatcacccagattgtggatgtctttatggaatacaaccttatccaa
caatgcactgctttcttattggatgctctaaaaaacaaccgtccaactgaaggtcctttg
caaacccgtctccttgaaatgaatctgatgcatgcacctcaggtggctgatgcgattttg
ggcaaccagatgtttacacattacgaccgtgctcacattgcacagctttgtgagaaagca
ggccttcttcagagagccttggaacacttcacagatctgtatgacataaaaagggcagtt
gtccacacacatcttttgaatcctgagtggctggtgaattattttggctccttgtctgtt
gaagattctctcgaatgcttgcgtgccatgctttctgcaaacattcggcaaaatttgcag
atttgtgtccaggtcgcttccaaataccatgagcagctttccactctgtcactcattgaa
ctttttgaatctttcaagagctttgaagggctgttttatttcttgggctctattgtcaac
tttagccaggatcccgatgtgcattttaaatatatccaggcagcttgcaaaaccggtcaa
attaaagaagttgaaagaataagcagagagagtaactgttatgatcctgagcgagtgaaa
aacttccttaaggaagccaagctcacagaccagctgccactgataattgtatgtgatcgt
tttgactttgttcacgaccttgtcctgtatctgtacaggaacaacctacagaaatacatt
gagatctatgttcaaaaggtaaatccaagtcggttgccagtagttattggaggcctgctt
gatgtggattgttcagaagatgtcattaagagtcttatccttgttgtgcggggacagttc
tctacagatgagcttgttgctgaagttgagaaaagaaacaggttgaaactgcttttgcca
tggctagaatctcgaattcatgagggttgtgaagagcctgccactcataatgctttggct
aaaatctacatagatagcaacaataatcctgaacgattcctacgagagaacccatactac
gatagccgcgttgttggaaagtattgtgaaaaaagggacccccatcttgcatgtgttgca
tatgaacgaggacagtgtgatctggaactaataaacgtttgcaatgaaaattctcttttc
aaaagcctttcccgttaccttgtacgtcgtaaggatccagaattgtgggccagtgtcttg
ctagaaagcaacccatataggagacctctaattgatcaggttgtgcaaacagctttgtct
gaaacgcaggatcctgaagaggtgtctgttactgtgaaagcctttatgacagcagacctt
cccaatgagctcattgaattgttggagaaaattgtattggacaactctgtctttagtgaa
cacagaaatctgcagaacctcttgattctgactgcaattaaagctgaccgcacaagggtc
atggaatatattaatcgtctggataattatgatgccccagatattgcaaacattgccata
agcaatgagttgtttgaggaagcatttgctattttcaggaaatttgatgtgaacacctca
gctgtgcaggtattgattgaacacatcgggaatttggaccgggcatatgaatttgctgag
cgatgtaacgaaccagctgtttggagtcagcttgccaaagcgcagttacagaaagggatg
gttaaagaagctattgattcctacataaaagcagatgatccttcttctttcatggaagtt
gttgaagctgctaatgccagtggaaattgggaggagttggttaaatacctgcaaatggct
cgtaaaaaggcacgagaatcctatgtggaaactgagcttatatttgctcttgctaaaaca
aatcgccttgcagaactggaggagttcattaatggaccaaataatgcacacattcagcag
gttggtgatcgctgctatgatgaaaaaatgtatgacgctgctaagctcctctataacaat
gtttcaaattttggacgtttggcatccacattggttcacttgggagagtatcaagcagct
gtggatggtgcccgtaaggcaaatagcacacgcacttggaaagaggtttgctttgcttgt
gttgatggaaaagagtttcgcctggcgcagatgtgtggccttcatattgtggttcatgct
gatgaattggaggagcttataaattattaccaggatagagggtattttgaagaactaatc
actatgctggaggcagctcttggactggaaagggcgcacatgggaatgttcactgaactt
gcaatcctttactccaaatttaaaccccagaaaatgagggagcacttggagcttttctgg
tcaagagtcaatattccaaaggtgctgagagcagcagaacaggcacacttgtgggcagaa
ttagtattcctgtatgataaatatgaagagtttgacaatgctatcatcacaatgatgaac
catgccacagatgcatggaaggaaggacaatttaaagatatcattacaaaggtcgcaaat
gttgaattgtattacaaagcaatccatttttatttggagttcaagccactgctactgaat
gatcttctgatggtgctctcaccaagacttgaccacacccgtgcagtaaactttttcacc
aaggtgaaacagcttcctctggtaaaaccatatctgcgttcagttcagaatcacaacaac
aaatctgtgaatgaggctttaaacaatctgttcattacagaagaagattaccaggcactt
cgaacctctatagatgcatatgacaactttgataacatttcccttgcgcaacgactcgag
aagcatgagctaattgaatttagaagaattgctgcatatctattcaagggcaataatcgt
tggaagcaaagtgtggagctttgtaaaaaagacaagctctacaaggatgctatgcagtat
gcctctgaatccaaagatacagaattggcggaggaacttctacagtggtttttggttgag
gagaaaaaggaatgctttgcagcctgtctctttacctgctatgacttgctgcgaccagat
gttgttttggaaacagcatggaggcacaacatcatggaatttgctatgccctacttcatt
caggtcatgagggagtacttatctaaggttgacaaattggatgcctcagaatccattaga
aaagaagaagagcaagcaacagagacacaacccattgtttatggccagccacagctgatg
ttgactgcaggacccagtgttccagttcctcctcaagctgcgtatggctatggctatact
gcacctgcatatgggcaacctcaacctggctttgggtattccatgtaa

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