Xenopus laevis (African clawed frog): 445832
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Entry
445832 CDS
T01010
Symbol
lrrk2.L
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
xla
Xenopus laevis (African clawed frog)
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xla01001
]
445832 (lrrk2.L)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
xla04131
]
445832 (lrrk2.L)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
xla04147
]
445832 (lrrk2.L)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
445832 (lrrk2.L)
Protein kinases [BR:
xla01001
]
Serine/threonine kinases: TKL group
LRRK family
445832 (lrrk2.L)
Membrane trafficking [BR:
xla04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
445832 (lrrk2.L)
Exosome [BR:
xla04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
445832 (lrrk2.L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
LRR_4
COR-B
COR-A
Ras
LRR_14
LRR_1
Ank_2
Arf
nSTAND3
WD40_CDC20-Fz
AAA_16
G-alpha
Gtr1_RagA
AAA_23
Arm
Kdo
T2SSE
PduV-EutP
AAA_7
Ank
NACHT
AAA_29
TniB
FtsK_SpoIIIE
TFCD_C
AAA_22
ABC_tran
NB-ARC
TsaE
Septin
ATP_bind_1
Beta-prop_EML_2
Sigma54_activat
WD40_Prp19
MobB
MMR_HSR1
Motif
Other DBs
NCBI-GeneID:
445832
NCBI-ProteinID:
XP_018108120
Xenbase:
XB-GENE-6252262
UniProt:
A0A1L8GZ36
A0A974DEI7
LinkDB
All DBs
Position
3L:81853355..81961420
Genome browser
AA seq
2514 aa
AA seq
DB search
MSNTEELEENVRKLVVRLNNIEEGKQIDTLVQILDDLYAHTLCDCAPKIFQDKNVLSPLL
LVLDFYGKVAVIQQAGWSLLCRLIEVCPAILHSLQTPTDLGKEWDILGVHQQILKILSIY
LTNIAVLTTGLKTLTVLLASDVMHFLLLDHEVDIFMLIFDAMRAFSNKEEIQIYGCKALY
LLLIKVPEQQLTEFIESKDHFILLRVLRDFKDKESVVLPALQVLLPLAGPSSNVEVLMSG
NVRCYNLITEAMKAFPDNEEMQEVCCCLFQKLTFGSFYNILVLNEAHEVIIQALTKYYSN
AKLQAAALSCLALLTETIFLNKDLEDGDNVEEIKGQAYWFQQSFKALKSHKKNTEVQEAA
CWALNNLLMYHHELHDKVGDEDHQYPVHKEVMLSMLMHSSSKDVFQASTTALATLSEYNV
NIRKVLLEKGVHINVIEIMKKHIGCPEATESACRVLQHLFNGSSFNLDIMVGALTVILSA
AKKHKNIPSVQLEAMRVLLQMVFEDEELKVQNNAAISEETLFLNLPQKVIKNQCLLEGTH
ILVLQAMNKFIGHRAIQECGLKVLQCLSECSGALDILSQQGALDTILHTLQMYPGDPEIQ
YFGLFLLAHLITRKNLCIATMHLLSTHLVSALHRYKDDVRIQEEGFLTVLTLVKLSHSFA
KLLDLEEFEKVIFYQISMCLANKRNMKFQKLCYGCFAEMTSEDDLKNTLLVKACADNYIV
IVECLLLLGADVNKKTKHTSLIIEVCEKGNNPKLVELLLNNGVREQDARKALNVSIKKCD
NEIISLLLKKLGLDAANNSICLGGFHMGRTEPSWLIPLFTEKQPLVKQPSVGQEGRKGSI
LARMVLRYHRKNSEIERCRSSGDLSFTEEIHEKSEDSLLHPDVFEEAGIPYSDVDSEGSG
GSLRMKKSNSFGNLDIHKLEHAKLWRRHCNSLGAWADEPIVHRKKDFPQMDYPGAKLSLN
MKRADSLSSLADKDHIKSLDLSTNDLENINLVLKKGSLTNHLERLEKLELQHNLLSSFPK
SLCEALRSLTYLDLRGNSFKYFPHHILEINCLVFLDVSRNEIGPNLDWNSSKMCPNLKQL
NLSYNQLITFPENIANIAQNLEELLLEGNHISEIHGQLCLPELHTINLNKNRIHFVETDF
LMNCVKLETISAMTNLLSIAPNLPQKITTVKLSQNQLTNIPTEILQLSHLRSIDLSNNQI
VHLPGPQEWASSNLREVNLNYNQISILNLRKDACRWSRLEKLHLSNNKIKEIPPEIGYLE
NITSFDISYNPDLRTFPDEMGKLTKVWDLPLDGLHLDIDLKHIGCKAKDLIRFLQQRLKK
AAPYNRMKLLIVGNTGSGKTTLVQQLMKCKRLEHGAEKATIGIDVKDWPILIRGKIKKEI
TLNVWDFAGQEEFYCSHPHFMSPQALYLVVYDLSKGVSEVDAIKPWLFNIKARASSSPVI
LVGTHLDVSDEKCQKACIGKIKQELYNQRGLPSIQEYHFVNANEESDPLAKLRKTIIKEC
LNFKIREQPVLGQLIPDSYLELEKKILNERKTVALEFPVISHERMLEIVEESQLHLDENE
LKHAVHFLNESGVLLHFEDPALQLRDLYFVDPQWLCKIIAQILTVRADGCQKYPKGIIHY
KDVETFLAKKKKFPKNYMSQYFKLLEKFQIALPLGDDQLLIPSSLSDHRPVIELPHCENS
EVIIRLYEMSYFPMGFWSRLINRLLEVSKYILSGRERAQRPNRMYWRQGIYLNWSPEAYC
LVESATLDRNPNSFLKVTVPSCRKGCILLGQVVDHIDSLMEEWFPGLLETDICEEGETLL
KKWVLYSFDDGQEHQKILLSDLQAKAEEGDLLVNSEDSRQTIPISQIAPDIVLADLPRNI
MLNAEELEFDQAPEFLLGDGGFGSVYRASYKGEDVAVKIFNKHTSSRLLRQELTVLSHLH
HPSLVYLLAAGVHPRMLVMELAPKGSLDHLLQQDSASLTRTLQHRIALHVADGLRYLHSA
MIIYRDLKPHNVLLFTLYPNSAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNV
IYNQQADVYSFGLLLYDILTGGARMVEGLKFPNEFDELAIHGRLPDPVKEYNCAPWPEVE
VLIKKCLKENPQQRPTSVTVYEILNSAELLCLMRNHVIFSMLTAECMVAASPLVKKHVVW
VGNGCTEKGQMCCIDLNKGGQTCEDFSDSRILCLTLVTLPGEKQNWIVAGTQSGEIITAD
LDELKIKHTLHKLTDSVTCLLFSCIQGQSQKKYHILAGTANGRIAIFENTAVKCAYAAPI
KVIDIGDNSTPVMCLCESTYSSEKNSVWGICGTKIFSLSSEFTVQKTIDTRTATLYSHGS
YSESNITCFAIDKYIYVAKKISPYVEIWDKKTEKICEVLDCVQFLKEDSRKRRKCKQEEA
YTSRVKALYLQKNTALWVGTGGGHILLIDLSTRQPIRIITSFCDSIRSMVPAQLDRGSIK
NVVLVLGCRCTPQKEIQSFLSVWDTNLPHEVQNLKKHNEIRQELADKLRGLSMD
NT seq
7545 nt
NT seq
+upstream
nt +downstream
nt
atgagcaacacagaagaacttgaagaaaatgtcagaaaactggtggttcgtctcaataac
atagaggaaggcaaacagatagatactctggtccagatacttgatgacttgtatgctcat
acactttgtgactgtgcaccaaaaatattccaggacaaaaatgtgctttctccactgttg
ttggtcttagacttctatgggaaagttgcagtaatacagcaggctggctggtctctattg
tgcagattaatagaagtatgtcctgctattcttcatagtttacagacccccactgacctt
ggaaaggaatgggatatacttggtgttcatcagcaaattctaaaaatcctgtctatctat
cttacaaacatagctgttttaactactggattgaaaactttaactgttctcctagcttca
gatgtaatgcattttttgctgttggatcatgaagtggatatatttatgctgatttttgat
gccatgagagcattttccaacaaagaagaaattcagatatatggatgcaaagcattatac
cttcttctaataaaagttccagaacagcagctgactgaattcattgaaagcaaggatcat
tttattctcttgcgggttttgagagacttcaaagataaagaatctgttgttctcccggca
ctgcaagtacttcttccattagctggcccttctagcaatgtggaagtgcttatgtctgga
aatgtaaggtgctataacttaataacagaggccatgaaagcttttccagataatgaagaa
atgcaagaagtttgctgttgtttgtttcagaaacttacttttggaagtttctataacatc
ttggtacttaatgaagcccatgaagtcattatacaggctcttaccaagtattattccaat
gcaaaactacaagcagctgctctcagttgtcttgctttacttaccgaaactatttttttg
aacaaagatttggaggatggtgataatgtggaggaaatcaaaggacaggcatattggttt
caacagtcatttaaagcattgaaatcacacaagaaaaacacagaggttcaggaggctgca
tgttgggctctgaataacctacttatgtaccaccatgaacttcatgacaaagttggggat
gaggaccatcaatatccagtacataaagaggtgatgctgtcaatgctcatgcattcttct
tccaaagatgttttccaagcatctactacagctttggccacactctcagaatataatgta
aatattaggaaagttctgctggagaaaggtgttcatataaatgttattgaaattatgaag
aaacatattggttgtcctgaagctacagaaagtgcctgtcgagttcttcagcatcttttt
aatggaagctcttttaatttggatattatggttggggctttgactgtgatattaagtgca
gcaaaaaagcacaagaacattccatcagtccaattagaggctatgcgtgtccttttacaa
atggtgtttgaagatgaagaattgaaggtacagaacaatgcagcaatttcagaagaaacc
ttatttttaaatctcccacaaaaagtaataaagaaccaatgcttgttagaaggaacacac
attttagttttgcaagcaatgaacaaatttattggccatcgtgctatccaagaatgtgga
ctgaaagtgcttcagtgtctttcagagtgctctggggccctggatattctttcacaacag
ggtgctctggataccattctgcacactcttcagatgtaccctggagatccagaaatccag
tattttggcttattccttttagctcatttgataactagaaaaaacttgtgcattgcaaca
atgcatcttttatcaacacatttggtttctgctttacatcggtataaagatgatgtcagg
attcaagaagagggattcttaactgtgttgacattagtgaagctatcacatagttttgca
aagctattagacctagaagagtttgaaaaagttattttctaccagatatcaatgtgcttg
gccaacaaacggaatatgaagtttcagaagttgtgctatggctgctttgcggaaatgact
tccgaagatgacctgaagaacactctactggtgaaagcatgtgctgacaattatattgta
attgtggaatgcttgcttctactgggtgcagatgtcaataagaaaacaaaacatacttct
ttaatcattgaggtctgtgagaaggggaacaaccctaaattggtggaattgttgttaaat
aatggagttcgagagcaagatgccagaaaagccctgaatgttagcattaagaaatgtgat
aatgaaataataagcttgcttttaaaaaagcttggtttagatgcagccaacaacagtata
tgccttggtggatttcatatgggcaggacagaaccatcttggcttattccactgttcaca
gaaaaacagccattggttaaacagccatcagtaggtcaagaagggagaaaaggttccatt
ttggcaagaatggttttgcgatatcacaggaagaattcagaaatagaacgctgtagatcc
tctggagacctgagtttcactgaagaaatacatgaaaaaagtgaagatagtctactccac
cctgatgtttttgaagaagctggaattccatatagtgatgtggacagtgaaggaagtggt
gggtcacttaggatgaagaaatccaattcctttggaaatctggatattcacaaactggag
catgccaagttatggagaaggcattgtaattcattgggggcttgggcagatgaacctata
gtacatcgaaaaaaagattttcctcagatggattatccaggtgcaaagttgtctttgaac
atgaagagggcagacagtttgtcttcgttagctgacaaagatcacataaaatcactcgat
ctttcaacaaatgatttggaaaatattaatctagttcttaaaaagggcagcttaactaat
cacttggaacgtcttgaaaaattagagcttcagcataatttattgtcatcttttccaaaa
tcactgtgtgaggccttgagatcattaacttacttggacttgcgtggcaacagcttcaaa
tactttcctcatcatatactagaaatcaattgccttgtgtttcttgatgtatcgagaaat
gaaattggtccgaatctggattggaattcaagtaaaatgtgtccaaatttaaagcagctc
aacctctcttacaaccaactgataacttttccagaaaacattgccaatattgctcagaac
cttgaagaattattattggaaggaaaccacatttctgaaatccatggacaactctgtttg
ccagaattacacactataaatctgaataagaacagaatacattttgttgagactgatttc
ctaatgaactgcgtaaaactggagacaattagtgcaatgacaaatttactgtctatagct
cccaatttgccacagaagataacaactgtaaaattgtcacaaaaccaattgacaaatatt
ccaacagaaattctacaactttctcatttacgaagcatagacttgagcaataatcagatt
gttcatcttcctggtcctcaggagtgggcatcatcaaatttgagagaagttaacttgaac
tacaaccaaatcagcattttaaaccttcgtaaagatgcgtgcagatggtcaaggcttgaa
aaattacatttatctaacaataaaattaaagagattcctcctgaaattgggtatcttgaa
aacatcacatcttttgacataagttacaaccctgaccttagaacttttcctgatgaaatg
ggaaaacttacaaaggtatgggaccttcctcttgatggactgcatttggacattgatttg
aaacacattggatgtaaggccaaagatctcataaggtttcttcagcaacgtttaaagaag
gctgctccctataatcgcatgaaacttttaattgtggggaacacgggtagtggaaagaca
actttagtacaacagctaatgaaatgcaaacgccttgagcatggtgcagaaaaagctact
attggtatagatgtgaaggactggcccatcctgatccgaggcaaaataaagaaagaaatc
actttaaatgtctgggactttgcaggccaagaggagttctactgtagtcacccacatttt
atgtctccacaagctttgtatctggttgtttatgatctgagcaaaggtgtttctgaggtt
gatgccatcaagccttggcttttcaacataaaagctcgagcttcttcatctccagttatt
ctggttggaacacacttagatgtgtctgatgaaaaatgccagaaagcctgtattggcaaa
atcaaacaggaattatataatcagcgtgggttgccctccattcaggagtatcactttgta
aatgccaatgaagaatcagaccctttggcaaagcttagaaaaacaattataaaagagtgt
ttgaattttaagataagagaacaaccagtacttggacagctgattccagatagttatcta
gagctcgaaaaaaaaattctgaatgagcgcaagactgttgcactggagtttcctgtaatc
agccatgagagaatgctagaaattgtagaggaaagtcaattacatttggatgaaaatgaa
ctaaaacatgcagtacattttctcaatgaatctggggttctgctgcattttgaagaccct
gctttacaacttcgagatctttattttgttgatccccagtggctatgtaaaatcatcgca
cagattttgactgtgagagctgatggttgtcaaaagtaccctaagggaattatacattat
aaagatgtggagacatttcttgcaaaaaagaaaaagtttcctaaaaattacatgtcacaa
tattttaagctgttggaaaagtttcagattgcattgcctctaggagacgatcaacttctt
attcccagcagcttgtctgatcacagaccagtgatagagcttcctcactgtgagaattca
gaggtcatcatacggttgtatgaaatgtcttatttcccaatgggtttctggtcaagactt
attaaccgcctcttagaagtgtctaagtatattctttctggaagagaacgagctcagcgt
ccaaacaggatgtattggagacagggaatttacctaaactggtctccagaggcttactgc
ttggtggagtcagcaactttagacagaaatccaaatagttttttaaaagtgacagtccca
tcctgcagaaaaggttgcattttactgggccaggttgtagaccacatagattctctgatg
gaggaatggtttccaggtctacttgaaactgatatttgtgaagaaggtgaaaccctttta
aaaaagtgggtgctgtacagctttgatgatgggcaagaacaccaaaaaatattgctgtct
gacctgcaggcaaaagcagaagaaggagacttgttggtcaattctgaggattcaagacaa
actattcctatctcccagattgcgcctgacattgtgctggcagaccttcctagaaatatt
atgttaaatgctgaagaactggaatttgatcaggctcctgaatttttgctgggggatgga
gggtttggatcggtgtatagagcatcgtacaaaggcgaagatgtagctgtgaaaattttt
aacaaacatacttcttcaaggcttttaagacaggaacttacagttcttagtcaccttcat
catcctagcttggtgtatttgttagcggctggagtacatccaagaatgttagttatggaa
cttgcacctaaaggctctctggatcatctcctgcagcaagacagcgctagcctcacaaga
actctccagcaccggatagctctgcatgtagctgatggactaaggtaccttcattcagcc
atgattatataccgtgatttaaagcctcataatgtccttctttttactctgtatccaaac
tcggcaattattgcaaaaattgcagactatggaattgcacagtactgttgcagaatgggt
attaaaacctctgagggtaccccaggatttcgggcacctgaggttgctagaggaaacgtt
atctacaaccagcaggctgatgtctattcatttgggttgttgctgtatgacattctgaca
ggtggagcccgcatggtggaaggtctgaaatttccaaatgaatttgatgagttggcaatt
catggaagattacctgatccagtcaaagaatataattgtgccccttggcctgaagttgaa
gtattgattaaaaagtgtttaaaagaaaatccccagcaacgtcctacatctgtcacggta
tacgagatcttaaactcagcagaactactctgtttaatgagaaaccatgtgatattcagt
atgttaacagcagaatgcatggtggctgccagtcctcttgtcaagaagcatgttgtttgg
gtaggaaatggctgcactgaaaagggacagatgtgctgtatcgatttaaataaaggtgga
caaacgtgtgaggatttttcggacagcagaatcttatgccttacactagtcacattaccc
ggagagaaacaaaactggattgtggctggaactcagtctggagaaattataactgcagat
ttagacgaacttaaaataaaacacactctgcataaattgacagattctgttacatgtttg
ttgttctcgtgcatccaaggacagagccaaaagaaatatcacattctagcaggtactgca
aatggccgaatagcaatttttgaaaatactgcagtaaagtgtgcatatgctgcaccaata
aaggtgatcgacattggtgataacagcactcctgtaatgtgtctgtgtgaatccacttat
tcatctgaaaagaattcagtctggggtatctgtgggacaaagattttctcactttctagt
gaattcactgtacaaaagacaattgataccagaactgccacactgtattctcatggctca
tacagcgaatccaatatcacatgctttgcgattgacaaatacatttatgtggcaaagaaa
atcagtccctatgtagaaatatgggacaagaagacagaaaaaatatgtgaagtccttgat
tgtgtccagttcctgaaagaagatagcaggaagagaagaaaatgtaaacaggaagaagct
tatacttcacgagtaaaagctttatatttgcaaaaaaatactgctctttgggtaggaact
gggggaggtcatattctgttaattgacttatcaactcgtcaaccaatacgaataatcaca
agcttctgcgattctattcgaagtatggtgcctgcacagttagacagaggaagtataaag
aatgttgtgcttgttttgggatgtcggtgcacaccacaaaaagagatacaatcatttctc
tctgtctgggatactaaccttccacatgaggtccagaatcttaaaaaacacaatgaaatc
agacaagaacttgctgataaactgagaggattatcaatggactaa
DBGET
integrated database retrieval system
