Xiphophorus maculatus (southern platyfish): 102223156
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Entry
102223156 CDS
T02923
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
xma
Xiphophorus maculatus (southern platyfish)
Brite
KEGG Orthology (KO) [BR:
xma00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xma01001
]
102223156 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
xma04131
]
102223156 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
xma04147
]
102223156 (lrrk2)
Enzymes [BR:
xma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102223156 (lrrk2)
Protein kinases [BR:
xma01001
]
Serine/threonine kinases: TKL group
LRRK family
102223156 (lrrk2)
Membrane trafficking [BR:
xma04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
102223156 (lrrk2)
Exosome [BR:
xma04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
102223156 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
COR
Roc
Ras
WD40_2
Ank_3
Ank_2
Ank_4
TniB
G-alpha
Arf
MMR_HSR1
SRPRB
Motif
Other DBs
NCBI-GeneID:
102223156
NCBI-ProteinID:
XP_023203095
Ensembl:
ENSXMAG00000002775
LinkDB
All DBs
Position
2:24617547..24657611
Genome browser
AA seq
2537 aa
AA seq
DB search
MVNKEELEGRLKKLLVRLKTPQEDRQLSTLIQILQDLRSLAATEHAAELFEDKDVHVPLT
VVLSSYTNSKKVQEVGLSLLCRLIEIWPNTLEELCRPLQASREWEVLAVHQQILKVLSKF
IADRQVTIVGLRALALLLTSDPIPLLVLDEEEDVFSLVVQAMKAFPTIEEVQLQGCRALQ
LLLDRVSDDHLGEFVENQDHVVVLSALQRFSNSPKLLTQAMKVLLPLARTGSNVEVLMSG
GTRCYAVIIAAMDAFPAVAELQETACLLFRRFTSASFYDILVRNGVQRVALRACQSFPNN
PVLQAAALSCLAELTATIVQSKAVAEKGRKEEERGMEEVEDVGLDWMEDCCTALDLHAAE
PAVQEAASWAIHNLLLHGAQVNPSEEEQDGRTPVHRQLMAAMLVHSSSPSVFIAATSAIA
TLITNNSKMSFLLLSGGLHVNLVEMMKRHASSAEVSISACKLLKLLFHGRTASLDELNMA
MNQILTTMKMHNFQSEVQLAALEASLIFLCPDRSLRENGSSIADPDMADVSLRVLKNQCV
VEGAHTLYLEALNRFISRPAIQQCGLKVLSFLADCSGAVDLLCQQGAIDTVLHTLHAFPE
DREIHYWGLTLLNYLVTKKKLSRMIVPVLASVVVASLSQYKEDSEMVLKCFQVALRMLDA
CSGAAAELQREDFDRQIFQHLIQEREQSVSPLRKAVCLALSKMWSDLELHYSMLEKACMD
GNTLMAECLIELGADINRKAKTESLIYQVCEKGGPLELVELLVSRGAPEQQLRRALAVSL
KRADGPIVILLLSRLGLDFNNSALCLGGFRLGRLDAAWLSPLLAERGRAYSLRYSSKGVD
LARYIQSLQRSKSVGGFSRPMSDQCLTSGYISDESDDSSFSAVSMDDSLFMNDEIESDGS
DPVLGTLSPKSKNNSVEELRGDSFKRKQGRHRHSSAESPQPENENNESTNVRCVRRNSKP
VLGSGENSAALFKERERIRLLDLSGNELDSLSCFLDNAVVQQQLWHVHRLDLSSNVLLDF
PSAICQSLKSVTRLDLQGNQLRSLPDDLLALPSLSTLNVSRNCIGPVLTFDPAVTCPSLR
QLNLSFNKITTFPYELGRTMGKLEELFMDGNGLTELCSALYLPEVKLLDVSKNNVENISP
DFLTTCPKLETLNASNNKICSFSQLPAKVTTLKLANNKFTHVPEAILNLPNLRSVDMRTN
TIDVLPGPGCWVSHNIRELMFSQNNIKGLDLSGPIFRWARLEKLHLSDNKLKEIPPQIGM
LEGLNSLDVSQNARLRSFPDEMGKLGRLWDLPLDGLRLDLDLKLIGNKTKDIVRFLQQRL
KKAVPYHRMKLIVVGTTSCGKSSLVRQLMKMKRSQLNSKQSAVDVFDWTVKKMLLNVWDF
SGGEELTGSHPLFLTSRALYLVVYDLSKGPSQVDALKPWLFNIKAVAPLSPVILVGTHTD
VSEELQIQSCLSKIREELLNHQGFPAIRDCHMVSLCEDPDSIAKLRRAVIREVTNFKIQG
QQVMGQLVPDCYVELERRILQERSRVPPEFPILRYDKLLQLIQESQLQLEEAELPHAIHF
LSEVGILLHFGDPALQLQELYFIDPQWLCNILSQKLTLKSCGLLEQPKGVVQRSVVERFL
LETKCFPKSHMLQFFKLLEKFQIALSFGEDQLLVPSSLSKHRPVIELPHCENSEMIVRLY
EMPYFPMDFWSRQISRLLEVSSYLLCGREKVLRPNLIYWRRGIYLNWSSDAYCLMEATSE
EQSPSSFVRITVPSSQKGRVLLGQVVDHVDSVLEEWFSGLLNTDMHGNGEALLKKWALYS
FEDGQEWSKILLEDLCNHFDEDFLMVNPENPRCKLLISQIAPDLVLSDQPAGISLDGEEL
EVDLSKEHRLGDGGFGTVYRGIYKTEEVAVKVFNKHASDLYVHRLLRQELVVLGRLRHPS
LVSLLAAGSAPPVLVMELAHRGSLDSLFNHENGSLNQKLQHRIALHVADGLRYLHTAMII
YRDLKPHNVLLFNLKSDSEIIAKITDYGIAQYCCSMGVRSSEGTPGFRAPEVARGNVIYN
QQADVFSFGLLLYDLLTRGERISEGMKFPSEFDEVAVQGKLPDPVKHYGCSPWLSFQALM
MDCLKESPQDRPTSAQVFDRLNSGEMLSLISEVKLSGMFTAQCITMSSSGAATGGDQKTS
SHTAWLGGGSSSKRKGYITAVDLHTNVVTTQEVDTSPVLCLVTVQIPNEEFDWLVAGMQS
GSLLVISTQDVSTYHHLQSVTDAVTSLYFHVHPRRTQRTNYLLVGTADGVLSVYEESVLM
RKNGQPVKSVTVGNGSTPLMCLGQSTHSLDSRTVWAGCGTKILCFSADYDVCKFIDTKPN
LIFRQQRGQSSEACVSRMVVDRHVYLSKASTPTVEVWDKKSERMVDCIDCAQIIRRGGGA
EPLSEASPSWATVKTLMMQNTAALWIGTRGGYLLLLELSKHQALQVVAPSCDSIRAIVSA
VIQSMNWKNAVLVLGRRLPRDRNRDGERPRLAPPLLYEESVLMAWSSTLPLEVTDLKKHC
EKRERAAARMREQLHHA
NT seq
7614 nt
NT seq
+upstream
nt +downstream
nt
atggttaacaaagaagagctggaaggaaggctgaagaagctgctggtgcggctgaaaacc
ccgcaggaggacaggcagctgtccacgctgatccaaatcctgcaggatctgcggtccctg
gcggcgacggaacatgcggctgagctgtttgaagacaaggatgtccatgttcccctcaca
gtggtgctttcatcttatacaaacagcaaaaaagtccaggaggtgggcttgtcactgctg
tgccggctcattgaaatatggccgaacacgctggaggagctttgcagacctctgcaggcc
agcagggagtgggaggtactggcagtgcaccagcagatcctgaaggtcttatctaagttt
attgcagatcgtcaagtaaccattgttggactcagagccctggcgcttctgctcacatca
gatccgattcctctgctggtgctggatgaagaagaggacgtgtttagcctggtcgtgcag
gcgatgaaggcatttcccaccattgaggaagttcaactccaaggttgtagggctctgcag
ctgctgctggacagagtaagtgacgaccatctgggcgagtttgtggaaaaccaggaccat
gttgtggttctctcagctctgcagaggttctctaacagccccaagcttctcactcaggcc
atgaaggtgttactgcccttagctcgcacaggcagtaacgtggaggtgttgatgtcagga
ggcactcggtgttacgccgtcatcatcgcggccatggacgccttccctgccgtggcggag
ctgcaggagacggcctgcctgctgttcaggaggttcacatcagcaagtttctacgacatc
ctggtacggaacggcgtccagagagtcgccctgagagcctgtcagagttttcccaacaac
cctgtcctgcaagctgcagctctctcctgcctggctgaacttactgcaaccatcgtgcag
agcaaagcggtggcggagaaaggacggaaggaagaggagaggggcatggaggaggtggag
gacgtgggcctggactggatggaagactgctgtacggcactggacctccatgcagccgag
ccggctgttcaggaagctgcgagctgggccattcacaatctgctactgcatggagcccaa
gttaacccttcagaagaggagcaggatggcaggactcctgttcacagacagttaatggct
gccatgctggttcactcctcctctcccagtgtgttcattgctgctaccagtgccatcgcc
acgctcattaccaacaacagtaaaatgagcttcttgctgctgtctggtggcctccatgtc
aatctggtagagatgatgaagagacatgcaagctcagcagaagtttccatcagcgcctgc
aagttgttaaagctgcttttccacggaaggactgccagcctggatgagctgaacatggcc
atgaatcagatcctcaccaccatgaagatgcacaacttccaatcagaggtccagctggca
gcactggaagccagtctgatcttcctttgcccagaccggagtttaagggagaatggttcc
tccatcgcggatcccgacatggccgacgtgtcgctgagagtcctgaagaaccagtgtgtg
gtggaaggggctcacacactctacctggaagccctcaacaggtttatcagcagacctgcc
atacagcagtgcggcctgaaggtgctttcattcctggctgattgctcaggtgcagtggat
ctgttgtgccagcagggggcgatagacaccgtacttcatacactacatgcgttcccagag
gatcgagagatacactattggggtctaaccctgcttaactacctcgtgacgaagaagaag
ctctccaggatgatcgtaccagtcctggcctctgttgttgtcgcctccctaagtcagtac
aaagaagattctgagatggtgctgaagtgttttcaggtggccctgaggatgttggatgcc
tgctcaggggcagcagctgaactgcagagagaagacttcgacaggcagatcttccagcac
cttatccaggagagggagcagagcgtcagcccactgcggaaagctgtgtgtctggctttg
tccaagatgtggagcgacttggagctacactacagcatgctagaaaaagcctgcatggac
ggcaacacgctgatggcagagtgcctcattgagctgggcgccgacatcaacaggaaggca
aaaacagagtctctcatctatcaggtgtgtgagaaaggaggtcctctggagctggtggag
ctcctggtgagcagaggcgctccagagcagcaactccgcagagctctagctgtgagcttg
aagagggccgacgggcctatcgtcatcctgctgctcagccggctcggtctggacttcaac
aacagcgccctctgtctgggaggcttccgactcggcagattggacgccgcttggctgagc
cccctcctggccgaacggggcagggcatacagtctgcgctacagcagtaaaggtgtggat
ttggccaggtacattcagtccctgcagaggtccaagagcgtcggcgggttttccagaccc
atgtcagaccagtgtctgacttccggctacatttcagacgagagcgatgactccagcttc
agcgccgtgtcgatggatgacagcttgtttatgaatgacgaaatagagagtgatggaagt
gatccagtgttggggactctgtctccaaagtccaaaaataactctgttgaggagctgagg
ggagactccttcaaaaggaagcagggacgtcacaggcactccagtgcagagagtcctcaa
cctgaaaatgaaaataatgaatcgactaatgtaagatgcgtacggagaaactctaagccg
gtgctgggctctggtgagaactccgctgctcttttcaaagaaagggagaggatccgcctg
ctggacctgtccgggaacgagttggactcgctgtcctgtttccttgacaatgctgttgtc
cagcagcagctgtggcatgtccatcgcctggacctgagcagcaacgttctgctggacttc
ccctctgccatctgccagagtttgaagagtgtgacccgtctggacctgcagggtaaccag
cttcggtcattgccagacgacctgctggctctgccctcactgagcacgctcaacgtctcc
cgtaactgcatcggccccgtgctgaccttcgaccccgctgtcacctgcccctcactgagg
cagctcaatctgtcattcaataaaatcaccacattcccctatgagctgggccggaccatg
ggaaagctggaggagctgtttatggacggtaacggtttaactgagctgtgctcggctctc
tatctcccggaagtcaagctgctggatgtgagcaagaataatgtggagaatatttctcct
gactttctgaccacctgccctaaactggaaactttgaatgcttcaaacaacaaaatatgt
tccttttcccagctgccagccaaggttacaacgttgaaattggctaacaacaagttcact
cacgttcccgaggccatactgaatctaccaaacttacgttcagtggacatgaggaccaac
accatcgacgttctacctggtccgggctgctgggtgtcccacaacatccgggagctgatg
ttcagtcagaacaacatcaaaggtttggatctgagtggaccgatcttcagatgggccaga
ctggagaagctccatctgagtgacaacaagcttaaagagatcccgccgcagatcggcatg
ttggaaggcctgaactctctggatgtgagtcagaacgccagactgcggtcgttcccggat
gaaatgggaaagctgggcagactgtgggacctgcctctggacggccttcgactggacctg
gatctgaaacttattggcaacaagaccaaggacatagtcaggttcctgcagcagcgcctg
aagaaggccgtgccgtaccaccgcatgaagctcattgtggtggggaccaccagctgcggg
aagagcagccttgtcaggcagctgatgaagatgaagcggtcccagctgaactcaaagcag
agcgctgtggacgttttcgactggaccgtcaagaaaatgttgctgaacgtctgggacttc
tcaggtggagaggagctcactggctctcaccctctcttcctcacatccagagcgctctat
ctggtcgtctatgacctcagtaagggacccagtcaggtggacgctcttaagccctggctc
ttcaacattaaagcagtggctccgctgtctccagtcatccttgttggaacccacactgat
gtgagcgaggagctgcagatccagtcgtgcctgagtaaaatcagagaggagctgctgaac
catcagggcttcccggccatcagagactgtcacatggtctcgctctgcgaggatccggac
tccatcgccaaactccgcagggcggtcatcagagaggtcaccaacttcaagatccaaggc
cagcaggttatgggtcagctggtgccagactgctacgtggagctggagcgcagaattctc
caagagaggagcagagtcccgccagagtttcccatcctcaggtacgacaagcttctgcag
cttatccaggagagtcagctgcagctggaggaagccgaactcccccacgccatccatttc
ctcagcgaagtgggaattttattacactttggcgaccctgctctccaacttcaagaactt
tactttattgacccacagtggttgtgtaacattctgtctcagaaactgaccttgaagagc
tgtggcctcttggagcaaccaaagggagtggtccagcgttctgttgtggaaaggtttctg
ttggagaccaaatgtttccccaagagccacatgctccagttcttcaaacttttggagaag
tttcagattgccctttcctttggtgaggaccagctactggtacccagcagtttgtccaaa
cacagaccagttatagaactacctcactgtgaaaactctgagatgattgtgcgtctgtat
gagatgccctacttccccatggacttctggtctaggcagatcagtcgcctgttagaggtc
tcctcatatttgctctgtggaagagaaaaggtgcttcgacccaaccttatttactggagg
cgaggtatttacctgaactggtcctctgacgcgtactgtctgatggaggctacttcagag
gagcaaagtccctccagctttgtcaggataaccgttccctcatctcaaaaaggccgggtg
ttactgggccaagtggtggaccacgttgactccgtactggaggaatggttttctggtctg
ctcaacaccgacatgcatggcaatggagaagctttgctaaagaagtgggctctgtacagt
tttgaagatggccaggagtggagcaagattctgctagaagacctttgtaaccattttgat
gaagatttcttgatggtgaacccagagaatccgcgctgcaagcttctgatttctcagatc
gccccagacctggtgctgagtgaccagcctgcaggaatttcactggatggggaggaattg
gaagtagacctctccaaagaacacagactaggggacggaggttttggaacagtttatcgc
ggaatttataaaaccgaagaagttgccgtgaaggttttcaacaagcatgcttctgatctt
tacgtccacagactcctcagacaggaactggtagtcctgggtcgtctccgacaccccagc
ctggtgagcctgctggctgccggctccgctcctccggtcctggtgatggagctcgctcac
agaggctctctggactccctctttaatcacgagaatggcagcctgaaccagaagctgcag
cacaggatcgccctgcatgtggcagatggcctcaggtacctccataccgccatgatcatc
tatcgggacctgaagccccacaacgtgctcctcttcaacctgaagagcgactcggagatc
atcgccaaaatcaccgactacgggatcgctcagtattgctgtagcatgggcgtgaggagc
tccgaggggactccaggtttccgagcgcccgaggtcgcccgggggaacgtgatctacaac
cagcaggcggacgtgttctcgttcggcctgctgctgtacgacttactgacgagaggcgag
cgcatttcagaaggcatgaagttccccagcgagtttgatgaagtggcggtgcagggaaag
ctgccagacccagtaaaacactatggctgctcgccttggctcagcttccaggctctgatg
atggactgtctgaaggaaagcccacaggatcgacccacctctgctcaggtgtttgaccgg
ctgaattcaggggaaatgctgagcttaataagtgaagtgaagctttccggcatgtttact
gctcagtgcatcacaatgagcagcagcggtgctgccaccggtggcgaccagaagacatca
agccacacagcctggcttggtgggggcagcagctccaagaggaagggctacatcacagcc
gtggacctgcacaccaatgtggtcaccacacaggaggtcgataccagccccgtcctttgc
ctcgtaacggttcagatcccaaatgaggaattcgattggctggtggcaggcatgcagtct
ggctccttactggtcatcagcactcaggacgtgtccacttatcaccacctgcagagtgtc
acagatgccgtcacctcgctgtacttccatgtacaccctcggcgcacccaaaggacaaat
tacttgctggtcggcaccgcagatggagttctgagtgtttatgaggagtccgtgctcatg
cggaagaatggccagccagtgaaaagcgtcaccgtgggaaacggcagcactccgctcatg
tgtttgggccagtcgacccactcgctggacagcaggacggtctgggccggctgtgggacc
aagatcctctgcttctcagccgactacgacgtctgcaagttcatcgacacgaaaccaaac
ctcatcttccggcagcagcggggtcagagcagcgaggcgtgcgtctcccgcatggtggtg
gacagacacgtgtatctcagcaaagccagcactccgaccgtggaggtgtgggacaagaag
agcgagaggatggtggactgcatcgactgcgcgcagatcatcaggcggggcggcggggcg
gagccgctctccgaggcgtcgccctcttgggccacggtgaagaccctgatgatgcagaac
accgcagcgctctggatcggcactagagggggctacctgctcctgctggagctctccaag
caccaggcgctgcaggtggtggcaccgtcttgcgactccatccgcgccatcgtctctgca
gtcatacagtcgatgaactggaagaacgcggtgctggttttgggccggaggctcccacga
gacaggaaccgggacggtgagcgtcctcgtttggccccgccgcttctctatgaggagtcg
gtgctgatggcgtggagcagcacgctccctctggaggtcacagacctgaagaagcactgt
gagaagagggagcgcgccgcggccaggatgagggagcagctccaccacgcctga
DBGET
integrated database retrieval system
