Xenorhabdus nematophila AN6/1: XNC2_1343 Help Entry XNC2_1343         CDS       T03752                                  Symbol rtxA Name (GenBank) toxin RtxA   KO K10953   RTX toxin RtxA Organism xnm  Xenorhabdus nematophila AN6/1 Brite KEGG Orthology (KO) [BR:xnm00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    02042 Bacterial toxins [BR:xnm02042]     XNC2_1343 (rtxA) Bacterial toxins [BR:xnm02042]  Type II toxins: Membrane damaging toxins   Pore-forming toxins, RTX    XNC2_1343 (rtxA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RtxA MLD Peptidase_C80 RtxA_C PMT_C2 ChaB Motif Other DBs NCBI-ProteinID:  CEK22337 LinkDB All DBs Position I:1241026..1255860 Genome browser AA seq 4944 aa AA seqDB search MGKSASRSTAYAFTGKYEDDNDGNTIHAIGIDGVINAYGGNDYIVVVSARAVVNTTWGHD TIVGGAGYLDVNDTGGDLTVKGASGFTSINKTQSGPITFEGVSGGVKINHTGDKSGIFYS GAAGYNSITRKGLQGDISFKGAGAYNELWHETNQGNFSFAGAGGANKIDRTWFNRYQGSH GDLTFKGAGAANIISSGVESGNVEFEGAGAANNIVRKGKIGDVTLRGAGASNHVERIREA DDVYSETKGNIRFEGVGGYNSLYSDVAHGDIHFAGAGGYNQITRKGTANDVNSEGIQYAK AEAIVLTKATMGGSWIGDTSYQVTGLKSAQQPNTYLFAFVDGTHTKINKVQLRNDPQTGK LIYHSTSWYKEGNHLSDIEKKDISEQGGFNATNTDGAYTLSNLTVESRQDAVFNAVQEKL VENKWMAYGGDILVNAADVTLLDAKMGGYAIGHNGETADVNVVKSNRKPNTYIYAKKVDS YTKIVVVELRNDPKTGILQYHAQAWLNNGDHVANLGNEDISPDNGYQALPGGIYVLSDLH YSAKAVRMSSGRVAKMREYSDQELFQSATDSGESSGDVHYNGAGGGNVIKSNVTRGNVYF NGAGIANIIEHSSDFGNTEFNGAGGANVIIKKGKEGNLSFNGAGIANVLLHQSQRGDMNI NAGGAANVLVRVGDGRYLAHLLAVGNISIHKGNGNSRISMGGGFNTHTQIGNGDAFWTGV GGANVLTQTGNGDVSSILIGGANVLTKMGGGHLESAMFGGANIITHISNNQGTSDTKAFN TKAIALGGANVLTKKGKGDVQAVMGGGVNVLTHVGDGKTTGVMLGGANILTKVGNGDTTG IMFGLGNVLTHVGNGQTLGVMVSAGNIFTKVGNDTTIAAMIGAGNIFTHVGEGNAWALMG GAGNIFTKVGNGDALALMLAFGNVFTHVGDGMSVALMIAKGNIATKVGNGDVLSAMIGKG NIFTQIGHGSTFAAMIGGANVLTKVGDDLTAALMIGEANIYTHVGKGTSIGLFGGSANIM TKVGDGTTLAAMFGKANIMTHVGDGLTGVLALGKANIVTKVGDDFMGVVAASEANIVTHV GDGTTAALLSGKGNILTKVGDGTTVGLLKSEIGNIMTHLGDGTTVGFAKGDANIITKVGD GLGINAAWGKANVMTHVGDGDRYNFAKGEANIITKIGDGQEVTVVQGQANIVTHVGNGDD YTGAWGKANVITKVGDGRNVVLAKGEANIVTQIGNGDSFNALWSQGNIVTKVGDGIQVTA AKGEGNITTTAGDGLNVTAVHGDLNINTKVGDGVSVNVAWGKLNVNTRVGDGLNVSVMKG KGNANIRVGDGLNINASYARNNVAIQVGNGDFYSFAVAESNTESNKLDALFANIKQTLLG SAGSQGINYLVNGDEASTSGTHKGRGAINLPEVSSLDGFKLTEIGEITSDLQNGLKGTVS GADEPNTDGIENALGNERRLNPNQQRNLIVNGDFEKGAEGWTYTNGIEASHSATAYGLSV EGHGERVSELDVSGNTHLYQDIKNLTADEKIVVKFDFARRAGSAADNGLEVWWNGKVVFA EANGNTEWQNKTLTLTAKAGSNRLEFSGVGRNDGLGYVLDNVVATSELSESHLAEHVKQD KAAQNALQDKAQAEADRQRLEQEKNNQLAAISGTQKQLENTDLNALNANGQSQRDAIDGE ARAFTDELKEKVKGLDALDSYATYDGKSGEQWHQFADGLKGRIQTQLDSTSETAKKQLAD SQQAAAGRLNDIKDAVAKSEAGVIDGEKNQLNAEQDIDKARAEAKFREQEATRQQQRAEQ AKHDGNLAAQKAEQRGQQEVFAANNKTAQVQSNAQGSKLDANYKPNRAGAAGSGLSGKVL TDSHNVSLESDAESGFDPNVELPAQTNAGFSAELQFIDEDLNELSNAKEALNRLQINAGV RARKASVGSSLTSAYTETPIHQPVSKVTRSSAEISRDTPRISGLDLSGLQALSETLAQPE SSDIPETVSAAAIRAQKVADVYRWLDSDNDFATEKYIPVPGFDRVDTDIPDDTRQKMVDF VERYISNTENSVPKEQAASLAKLFVDATIDYDWDKRVEFISRLEHYGYSFEPVHGDKSIV SFWSGKNFKQYRDILDAAQLDGKKVVYDIDVKGNAFAIQLNKTLTRWSGFYLDSDNADQK ALQSAIDASAYSNTGFWSSLYATGSRDDVYVIAEGGLRLGNYFWNVELPVLRQLQREGLV GEIRLLDKTAKEYADVPPESIGRRLTDAGVPVKARFDSLSFEEQKRLLALNPDGYKPDTL INLDIKTSAIDSLLNKALPFYGLRTERNLLVRKSEDGKGFKVRPWPGNHRDEFKTIMVDD PKDSNQIKAIERFILANYDNYGKLPEALYLADDRIVSYDQGRTRIVAKKVEGSWNYKPKA ELISAAELQEAAYVKGKILGDSYRNVLDALRDYENTLQNSKDYDLNAVEKLTYLHHQVEG YLLGHPDSARIPALKNLLSQINVRMEESLILAEPALKSAGKGNFSELYNKLGNAKLKDSK HLYIDEQGDFVTRGKSNIQIAMKAESAENAVEQVKAAVTREYGQSVTDAVFANLNTRDLA KDGKGIDVSGLKKVHHAIEQQLSPVSATLFVWKPSDHSSLGHAALQIGQGRIQISAEKAG EFNEKNYVSWWPKGIKSPNIGDIFNVSSEHNPDVRLRWRDLSQPARQHTLLKTDVAFEEG DKFGMQDGSYKLAKFNKELEVAKEGYARFADFSENTAIMMLENPKILQSAGIPESISRPF VERVEAGGADVFELGKEFAEALRTAAKQQHTPELAEEHTANIIRQFAEHELSDIQGFKTS EADQGRVFRISLAGLDAAAMQAEWQKISQNPDARYQLLNGNCSSIVAKVLKAGGADKIIG HTWRPKFGVWTPTELFNFAQKLQEVQIETAAKKQPYSPVEELAALSGKNKTLETVIAEND GTPSLNELITKDGLRKKASVFAKPIGPAYQAILDKLDHIHNLTGNEQLSAGFELYQRITR YLNEHPDSKRNTALSGVQTQLGDIMFRGALQEVRSPLLEIAQTRPEMASRIYQIARNEAR GDTPGLTDLMVRWVKEDPYLAAKLGYQGEIPADLAFNPKFHVDLGDQFDDFKQCLSKAQD KGLLINARIDEQNKRVHLGYSYNELLDMTGSEDVKMAVYFLKEVAKQADPNFAGSHEAIL LNRFANPAYLVQLEQGRLAQIEAIYHSSHQTDIAAWDKQYSSDALTQLNRQLSDGTDLNS QLSLLLKDRQGLLIGESHGSDLNGLRFVNEQMDALKVHGVTVIGLEHLRSDLAQPLIDKF LAGGDMPAELTAMIETKHLPVDLFEQAKSKGIKIIALDDNSTTRPAIEGSQHGLMYRAGA ANNVAVKRLGLLAEGEKFVAIYGDAHLQSHEGIDHFVPGMTHRLGLPALKVDANNRFTAQ ADDISLRKHYDDVPQLEKNLYKPNRVVGGDLEVLGHSDESEILKGTKSLLKRYLEVLKPE VNSAGITTKDIRTTKDFLVGYKQGYAEQIVDGFRSKMDVKQLVDLLVKGDWSAEQKGALA WEIESRALKITFQPKAEKFNRLFRDVASAGIADTKANEQAAPQLLLLNLSNDGFDGRCDP LSKLVLVAKQLENDGQDGVARQLLEKMYSAAAVLSKPNRYSETEHANASKLLGSLAALHA KNPMANTFTKVWKEKLEDAKALTIDGVVQKITAGNADGKPVLLELDAPGHAMAAWAKGSG ENRVYGFYDPNVGIVEFSSAEKVGAYISRFFGESDLNMAQRYQLPKNEAGEIVFKRVVVM DGEILATYRPIPADKTTMRGMLELPVFDDTPIRKPTDIDATDGIKKPLGDNSPESHIRVN NHDVGSWENITVKPQPESGDSRFSGQIIIQTENDPVAAKAAANLAGKHPDSSVIVQLDAN GQYRVVYGDPADLSNKLQSGKLRWQIVGHGREESAQNHTRISGYSADELALRLKQFSIDF KQAGKPDHISLVGCSLISDDKRNGFARRFISALNEQGVRTTVSARSSEVAVDSIGRKYTK DAQDQWVHKLTDNKIVLGWNDKGEVESHSERVRRGISENDIFLSRVGHTAVDAKAQGAIA DNVETFHAPKKRNENGENNPATSLKSNKQLSYSGNIQLQVGDGEFTAVNWGTTNVGIKMG TGGFKSLAFGDNNVMVHIGNGDSKHSVDIAGYQALEGAQLFVGNRNISFNWGRSNDLIVM LEKSIPTPPLVNPFDGAARISGVLQNIAGSYDSPDWLTTQNQQWTLESAKKYVSDLSGLD LTSSVDYKTLTDLDSQNERSSRGLKSDIESTLNKQFNQWLGKSGNTLDMGKISRADKFRQ ANEKLAFNFAVGGQGADIQVTTGNWNFMFGDNIQSILDTNLGSLFGLMKQEYTSTGMAKT TFTFSPKDLPRQIKNKLLGDLAGVSADTTLADIFGVDYTADGKIVSRSNQPVDGVAILRE MLEIIGEFSGSQLQAFTDREKLRDGLRAALDLGADGVKSFAESHGLKAAAPDEKQSEHVS INEENKPVPTTEELQADRALGLNSLNLPNLFATLFSKNKQTEMKSQVTNLKENLTADLLN IQDKTFDFLRNSGHLKGNGDINVSLGNYNFNWGGDGKDLGAYLGENNNFWGGRGDDVFYS VGTSNIFTGGAGNDTGVMMGRENMMFGGAGNDVAVLAGRINYAYMGEGDDQVFAFGEGGM IDAGKGRDYIVASGNFNRIEAGEDQDYVVTIGNNNQVDLGEGNDFARVFGNYNRIDGNTG NNSIKLMGYHAMINGGTGNDHLIADVVSKFSQFDGGDGDDLLVLGGYQNSFKGGTGVNSY VVSGDVIDNVVEDIKQGDKIIFNDINWQNLWFQRSGYDLVLSTHRNVKDSSAQGQFEAMG SVTFNNYFNGNRADIITQMGDKDAQGEREYTALSANGVDSLVQAMSGFAPNMGDSGFIDS LDSQTKSTIVTAWSDTTNGKSRLA NT seq 14835 nt NT seq  +upstreamnt  +downstreamnt atgggaaaatcagccagccgaagtacagcatatgcctttacaggtaaatatgaagatgac aatgatggaaacaccatacatgccataggcatagatggagtcattaacgcctatggcgga aatgattacatcgttgttgtatccgccagagcagttgtcaatacaacatggggacacgat accatcgtagggggagcggggtatctggatgtcaatgataccggtggcgatctcaccgtg aagggagcctctggcttcacgtcaatcaataagacacagagtggaccgataacatttgaa ggcgtctctggtggggtgaaaattaatcataccggtgacaaaagtggtatcttttattct ggagccgctggatacaatagcatcacccgcaaaggattgcagggcgatatcagttttaag ggcgcaggggcgtataacgaactctggcatgaaaccaatcagggtaatttctcctttgcg ggagcgggtggtgcaaacaagatcgatcgtacttggttcaatcgttatcaaggttctcac ggtgatctcacgtttaaaggtgcgggtgctgcaaacatcatcagttccggagttgagagc ggaaatgtcgagtttgaaggtgccggggcagccaacaatattgtccgtaaaggcaaaata ggtgatgttacattacgcggtgcgggtgcttctaatcatgttgaacgtatccgtgaggca gatgatgtttactctgagactaaaggaaatatccggtttgaaggcgttggtggttataac agcctgtactctgatgtcgcgcacggggatatccattttgcaggagcgggtggctataac caaattacccgtaagggaaccgccaatgatgtcaatagcgaagggattcaatatgccaaa gctgaagcaattgtcctgacaaaagcgactatgggggggtcatggattggggacacctcc tatcaggtgacgggtcttaaatcggcacagcaaccgaacacttatctgtttgcgtttgtg gatggtactcatactaaaatcaacaaagttcagctccgcaatgatccacaaacgggcaaa ctaatctaccactcaacgtcttggtataaagaggggaatcatctctcggatattgagaaa aaagatatttctgagcagggtggttttaatgcaaccaatactgatggtgcatacaccctg tcgaatctgacggttgaaagccggcaggatgccgtatttaatgccgtccaagaaaaattg gttgaaaacaaatggatggcctatggcggggatattctggttaatgccgccgatgtgaca ttgttagatgccaaaatgggcggctatgcaattggtcataatggagaaaccgctgatgtt aatgtggtgaaatccaaccgtaaaccgaacacctatatttatgccaagaaagtcgatagc tacactaaaattgtggttgttgagctaaggaacgatccaaaaacaggaatactgcaatat cacgcacaagcctggctcaacaacggagatcatgtggcaaatctggggaacgaagatatt tctcctgacaacggctatcaggccttgccgggaggtatttatgtactcagtgatcttcat tacagtgccaaggcggtacgcatgtcttctggacgtgttgccaagatgcgtgaatatagc gatcaggagttattccaatcagcaaccgacagcggagaaagctctggggatgttcattat aacggtgcgggtggcggcaacgttatcaaatccaacgtaacgcgcggtaatgtttacttt aacggtgccggcattgccaatattattgaacacagttctgacttcggcaataccgagttc aatggtgcaggtggtgccaacgtcatcatcaaaaaaggtaaagaaggcaacctgagcttt aatggtgccggcattgctaacgtactgcttcaccagagccagcgcggtgacatgaatatc aatgcgggcggtgcagcaaacgtgctggttcgcgttggtgatggccgctatcttgcccat cttctggccgtcggcaatatatctattcacaaaggtaatggtaacagccgcatctctatg ggcggtggtttcaatacccatacacagattggtaatggtgatgccttctggacgggtgtc ggtggtgcgaatgttctgacccaaacggggaacggtgatgtttcctcaatactgattggt ggggcaaacgttctgaccaagatgggtggaggtcatctggaatccgccatgtttggtggt gccaacatcattacccatatcagcaacaatcagggtacttccgatacaaaagcgttcaat accaaagccattgccttgggcggggccaatgtcctgacgaaaaaaggcaagggtgatgta caggcggtcatgggagggggtgttaacgtactgacacatgttggtgacggcaaaaccact ggtgtcatgctgggcggcgcgaacattctgactaaagtcggtaacggtgataccacgggc attatgtttggtctggggaatgtgctgacccatgtcggaaacggccaaacactgggcgtc atggtttctgccggtaacattttcaccaaagtcggtaatgatacaacgattgctgccatg attggggcaggcaatattttcacccatgtgggtgaagggaatgcctgggcactgatgggg ggggcaggcaatatctttactaaagtcggtaatggtgatgctctggcgctgatgctggca ttcggcaatgtgttcactcatgttggtgatggcatgagtgtggccctgatgatcgccaaa ggcaacattgcaacgaaagtcggtaacggtgatgtactgtctgccatgattggcaaaggc aatatctttacccagattggtcatggttccacgtttgccgccatgattggcggggccaat gtgctgaccaaagtcggcgatgacctgacggcagccttgatgataggtgaagccaacatt tatacccatgtcggaaaaggaaccagcatcggcttatttggcggctcagctaacatcatg acgaaagtgggtgatggtacaacgctggctgccatgtttggcaaagccaatatcatgact cacgttggtgatggtttgacgggcgtactggcgttaggcaaagccaacatcgtgacgaaa gtcggtgatgatttcatgggcgttgtggcggcttcggaagctaacatagtcacccatgtc ggcgatggcacgacggcggctttattgtcaggcaaaggcaatatcctgaccaaagtgggc gacggaaccacggtcggtttattgaagtccgaaatcggcaacatcatgacccatcttggt gatggtaccacagtcgggtttgcaaaaggtgatgccaatatcatcactaaagtgggtgat ggattgggcatcaatgcggcctggggcaaagccaacgtcatgactcatgtcggtgacggc gatcgctataattttgccaaaggtgaagccaatatcatcaccaaaatcggcgatggtcag gaagtcactgttgttcaggggcaggccaatattgtcactcatgtaggcaacggtgatgat tacactggagcctggggcaaggctaacgtcattaccaaagtgggtgatggccgcaatgtg gttctcgccaaaggtgaagccaatattgtgactcagatcgggaatggtgacagctttaat gccttatggagtcaaggtaacatcgtcaccaaagtgggtgatggtatacaagtcactgcc gccaaaggcgagggcaatatcacaacgacggccggggatggcttaaacgttactgctgtt catggcgatctgaatattaataccaaagtcggtgatggtgtttcagtcaatgtggcttgg ggcaaactcaacgttaatacccgggtaggtgacggcctgaatgtttctgtcatgaaaggc aagggcaatgccaatatccgtgtgggtgacggtttgaacatcaatgcttcttatgcccgc aataacgtggctattcaggtaggtaacggtgatttctatagctttgccgtggcggaaagc aacactgagagcaataagctggatgccctgtttgctaatataaaacaaacattgcttggc agtgcaggcagtcaggggatcaattatctggtcaatggtgatgaagccagcacatcagga acccataaaggacgcggtgccattaatctgccggaagtctcttctttggatggctttaaa ctcactgaaattggtgaaatcacttctgatttgcaaaatggcctgaaaggcacagtgtca ggtgctgatgagccaaatactgacggcattgaaaatgcactcggcaatgaaagacgcctg aatccaaatcagcaacgcaacttgatcgtcaatggtgattttgaaaaaggtgctgaggga tggacgtacaccaatggcattgaagccagccattccgctacggcatacggactcagtgtt gaaggacatggtgagcgtgtcagtgagcttgatgtcagtggtaatacacatctctatcag gatattaagaatctgacagcggatgaaaaaattgtcgtgaagttcgattttgcaagacgt gctggtagcgctgcggataacggtctggaagtttggtggaatggtaaggttgtttttgcc gaggccaatggcaacaccgaatggcaaaacaagacactgaccttaactgccaaggcgggc agcaaccgcctggaattttccggggtaggtagaaatgatgggttgggctatgttttggat aacgtggtggcaacctctgaactgtcagaaagtcaccttgctgagcatgtgaagcaggat aaagcggcacagaatgccttgcaggataaagcacaggcagaagctgaccgccaacgtctg gagcaggaaaaaaataaccaacttgccgctatttccggcacccagaaacagcttgagaat actgatctgaacgccctgaatgcgaacggacaatctcagcgcgatgccattgatggcgaa gcacgagcattcactgatgaacttaaggaaaaagtcaaaggtctggatgcgttggatagc tatgcgacatatgatgggaaatcaggtgagcagtggcaccagtttgcggacggattaaag ggtcgtatccaaacccaattggacagcacaagcgagacagcaaagaaacagttggcggac tcacaacaagcagcagcaggccgcctgaatgacattaaagatgcggtagccaaatcagaa gctggtgtcattgacggtgaaaaaaaccaactgaacgccgagcaggatattgataaagca cgggccgaagccaagttcagggagcaagaagctacccgccagcagcaacgggctgaacag gcaaaacatgacggtaatctggcagcacaaaaagcagagcaacgtggtcagcaggaagtg tttgcggcgaacaataaaaccgcgcaagtgcaaagcaatgctcagggttcaaaacttgat gccaactataaaccaaaccgggcaggggctgcggggagtggtttatcaggcaaggtgctt actgatagccacaacgtgagtcttgaatcggatgctgaatcgggttttgatccgaatgtt gaattacccgctcagactaatgctggatttagtgcagagttacaattcattgatgaagat ctgaatgaactcagcaatgctaaagaagcgttaaatcgtttgcagatcaatgcgggtgtg cgggcgagaaaagcctcagtgggatcttccctgacttctgcctataccgaaacgccgata catcaacctgtcagtaaagtaacccgttcatcggctgaaataagcagggatacacccaga atttccggtttggatctcagtggattgcaagcactgagcgaaacccttgctcagccagaa tctagtgatataccagaaaccgtttctgccgcagcgataagagcacagaaagtggccgat gtttaccgttggctggacagtgacaacgattttgccaccgaaaaatatatccccgtgccg ggatttgatcgtgttgatactgatattcctgatgataccagacagaaaatggtcgatttt gtcgagagatacatcagcaatacggaaaacagtgtaccgaaagaacaagcagcctcgctg gcaaaactgtttgttgatgccacgatagattatgactgggacaagcgtgtcgaatttatt tcaaggctggagcactacggctacagttttgagccggttcatggtgataaaagcattgta tcgttctggtcaggcaaaaactttaagcaataccgtgacattcttgacgcagcacagctt gatggtaagaaggttgtttacgatattgatgtaaaaggtaacgcttttgccattcaactg aacaagactttaacacgttggagcgggttttacctcgattctgataatgctgaccaaaaa gcattgcaatctgccattgatgcttctgcctatagcaacaccggattctggagttccctc tatgccacaggatcgcgtgatgatgtgtatgtcattgcggaaggtggcctgcgtctcggc aactacttctggaatgttgaattgcctgtattgcgtcaattgcaacgtgaagggctggtg ggtgaaatccggttgctggacaaaacagccaaagaatatgcagatgtgccgcctgagtcc attggtcgcaggttgacagacgcgggtgttcctgtgaaagcgcgctttgactcactcagt tttgaagaacagaaaagactgctggcgctgaaccctgacggatataaaccggatactctg attaatctggatatcaaaacaagtgcgattgacagcctgctgaataaggcattgccattt tatggcctgcgtacagagcgtaatttactggtgcgtaaatcagaggatggtaaaggcttt aaagtccgtccgtggccgggtaatcaccgtgatgaatttaagaccatcatggtagacgat ccgaaagattcgaatcaaatcaaagctattgagcgctttatccttgctaactacgacaat tacggcaaactgcccgaggcgctgtatctggcggacgatcgcattgtttcctacgatcag ggacgtacccgtattgtggcgaaaaaagtggaaggcagctggaactataaaccgaaagca gagctgatatctgcggctgaattacaagaagcggcttatgttaagggtaaaatcctcggt gacagttaccggaatgttctggatgcactcagggattatgaaaatacgctgcaaaacagc aaagactatgacttgaacgcagtagaaaaactgacctacttacatcaccaggttgaaggg tatttattaggacacccggattctgcgcgaattcccgcgttgaaaaacttgctgtcgcag atcaatgtgcggatggaagaatccctgatactggcggaaccggcgttgaaaagcgcaggc aaaggcaatttcagcgagctttacaacaaactgggtaacgccaaactcaaagattccaaa catctctatattgatgagcaaggggactttgttacccgtggcaaatccaatattcagatc gccatgaaagcagaaagtgcggaaaacgcggttgaacaggtcaaggctgccgtgaccaga gaatatggtcagtctgtgactgatgcagtcttcgcaaacctgaatacccgtgatttggcg aaagatggtaagggaattgatgtctctggcttgaaaaaagtacatcatgcgattgaacaa caattgtctccggtcagcgcaaccctgtttgtctggaaaccgagtgatcatagcagcttg gggcacgccgcattacagattggacaaggacgcatccaaatcagtgcagaaaaagccggt gaattcaacgagaaaaattacgtcagctggtggccgaaagggataaaatctcccaatatt ggcgacattttcaatgtttcttctgagcacaatccggatgtgaggctgcgttggcgtgat ctcagccagcctgcccgccaacataccttactgaagactgatgttgcttttgaggaaggc gataaatttggcatgcaggatggaagctacaagctggcgaaatttaataaagaacttgag gttgccaaagagggttatgcaagatttgcggatttcagtgaaaacactgccataatgatg cttgagaatcctaagattctacaatctgcgggtataccggaatccatctcccgacctttt gtggaacgggtggaagctggcggcgctgacgtgtttgaattaggcaaagaatttgctgaa gcactgcgtacggctgcgaaacaacaacacactcctgaactggcagaagaacacactgct aatatcattcgtcagtttgcggaacatgagctgagtgatattcaaggcttcaaaaccagt gaggctgatcaggggcgtgtattccgtatcagtctggcgggattggatgcagcggcaatg caggcggaatggcagaaaatcagccagaatccggatgcccgttatcagctgttaaacggc aactgttcaagtatcgtagccaaagtgctcaaggcaggaggcgctgataaaattatcggc catacatggcggccaaaatttggggtttggacaccaactgaattattcaattttgcgcaa aaattacaagaagtgcagattgaaacggcagcaaaaaaacaaccctactcccctgtggag gagttagccgcgttatcgggcaagaataagacactagaaacggtcatcgcggagaatgat ggcactccatcgctgaatgaacttataactaaggatggcttgcgtaaaaaggcctcagtt tttgccaaaccgattggtcctgcttatcaggcaattcttgataaacttgaccatattcac aacctgactggaaacgagcagttatcagcaggattcgaattgtatcaacgtattacccgt taccttaatgaacatcctgattctaaacgcaatactgccttgagcggcgtacagacgcaa ttgggagatattatgtttaggggtgcattacaggaagtacgtagcccgttgctggagatc gcccaaactcggcctgaaatggcatcgcgaatctaccaaattgcccgtaatgaagcccgc ggggataccccaggactgacagatctgatggtgcgttgggtgaaggaagatccttatctt gctgctaagctaggttatcaaggggaaattcccgctgatctcgcttttaatcctaaattc catgtggacttgggtgatcagtttgatgatttcaaacaatgcctgagtaaagctcaagat aagggattgctgattaatgcccggatagatgagcagaataaacgggttcatcttggctac agttataatgaactgttagatatgaccggatctgaagatgtgaagatggcggtctatttc cttaaggaagtcgctaaacaagcggatccaaatttcgctggttcacacgaagcgatttta cttaatcggtttgctaaccctgcctacttggtacagttggaacagggtaggctggcacag atagaagcgatatatcacagttcccatcagacagatatcgcagcttgggacaaacaatat tcctcagacgcactgacacaactcaatcgtcagcttagtgacgggacagatctgaatagc cagttgtcgttgctacttaaggatcgtcaaggattgctgatcggtgagagtcatggttca gatcttaatggattgcgttttgttaatgagcagatggatgcgttgaaagttcatggagta actgttattggattggagcatttgcgttcggatttggctcagccgttgatagataagttc ttggccggtggagatatgcctgctgagctgaccgctatgattgaaaccaaacatttgcct gttgacttatttgagcaggccaaaagtaaggggatcaaaatcattgcattggatgacaac agcacaactcgtccggcaatagaaggatcacaacatggcctgatgtatcgtgctggtgcg gctaataatgtggcggttaagcgtttgggactattagctgagggagagaaatttgttgcc atttatggtgacgcccatctgcaatcccatgaaggtattgatcattttgtacctggcatg actcatcgtcttggtttaccggcccttaaagtggatgcaaataaccgtttcacggctcag gcggatgatatcagtctgcgcaagcattatgacgatgtaccacagcttgaaaaaaatctt tataagccgaatcgagttgtcggtggagatctggaagtactgggtcattctgacgaatca gaaattcttaagggcacaaaaagcctcctgaaacgctatcttgaagtcctgaagcctgag gtaaacagcgcgggcataacaaccaaggatatccgtacaaccaaggattttcttgttggc tacaagcaaggttatgcagagcagatagtagatggtttccgttcgaagatggacgtcaag caattggtggatctgctggttaaaggtgactggagtgccgaacaaaaaggtgctttggct tgggaaattgaaagcagggcgttgaaaattaccttccagccgaaagcggagaagtttaat cgtttgttccgtgatgtcgcttcagcaggcattgctgatactaaagcgaacgaacaagcg gcaccacaattgctactgttgaacttatcaaatgatggttttgatggccgttgtgaccca ctgtcgaaattggttctggttgcgaaacaacttgaaaacgatggtcaggatggtgttgcc cgtcaattgctggaaaaaatgtattctgcggcagcagtactcagcaaacctaatcggtac tctgaaactgagcatgctaatgcaagtaaattattgggatcgttagcggcactccatgcc aaaaacccgatggcgaatacatttaccaaagtgtggaaagagaagctggaagatgcgaaa gcactgactatagatggtgtggttcagaaaatcactgccggaaatgcggatggtaaaccc gtgctgcttgaactggacgcaccaggccatgcaatggctgcgtgggcgaaaggcagtggt gagaatcgtgtttatggtttctatgatccaaacgtgggaattgtcgaattctcatcggca gagaaagttggcgcttacatatctcgcttcttcggtgaatccgacctgaacatggcacaa cgctaccaattaccaaagaatgaggcaggggaaattgtcttcaagcgagtcgtcgtgatg gatggtgagattttggcaacttatcgcccgataccggctgataaaacgaccatgcgcggt atgttggagctgcctgtgtttgatgacaccccaatcaggaaaccgacagatattgatgca actgatgggataaagaaaccattaggtgacaactcaccggaaagtcacattcgtgtaaac aaccacgatgttggatcctgggaaaatattacggtcaaaccacagcctgaaagtggtgat agtcgctttagcggtcagattattatccagacggaaaatgatccggttgcggcgaaagct gctgcaaatctggccggtaagcaccctgattccagtgtgatcgtccagcttgatgccaat ggccagtatcgcgtggtgtatggtgatcctgctgatttatcgaataaattacagtccggt aaattgcgctggcagattgtgggtcatggtcgtgaggaatccgcacagaaccacacacgc atcagtggctacagtgcggatgaactggccctgagactgaaacagttcagtattgatttc aaacaggccggtaagcctgatcatatcagccttgtgggttgttctttgattagcgatgac aagcgcaatggttttgcccgtcgctttatctcagcattaaatgagcagggtgtccgcacg acggtatcggcgcgtagcagtgaagtggcagtagacagtattggccgcaaatatacaaaa gatgcgcaggatcagtgggtacataaactcacggataacaaaatcgtcttgggctggaat gacaagggcgaagtcgaaagtcattctgaacgcgttcgccgtggtatctctgagaatgac atcttcttgtcccgcgtgggacataccgccgttgatgcaaaagcgcagggtgctattgcg gataacgtagagacattccatgcacctaagaaacgcaatgaaaacggtgaaaataatcct gccacttcattgaaatcaaacaagcagctgagctattccggcaatattcagctacaagtg ggtgacggtgaatttaccgcagtgaactggggaaccaccaacgtaggtatcaaaatgggt acagggggctttaagtctctggcctttggtgacaataacgtcatggttcacatcggtaac ggtgacagcaagcacagtgtcgatattgcgggttatcaggcattggaaggtgcacaattg tttgtgggcaaccggaatatcagcttcaattggggacgcagtaacgatctgattgtgatg ttggaaaaatccattccgacaccgccgttggtgaacccatttgatggtgctgcccgtatt tccggggtattgcagaacattgctggttcatatgactcaccggattggctgactacacaa aatcagcaatggacattggaaagcgcgaagaaatatgtcagtgatctgtctggcctcgat ttgaccagcagtgtggattataaaaccctgactgatctcgactcacaaaatgaacgcagc agccgtggcttgaagagcgacattgaaagcacactgaacaagcaattcaaccagtggttg ggaaaaagtggtaatactcttgacatgggtaaaatcagtcgtgcggataaattccgtcag gcgaatgaaaaactggccttcaactttgccgttggcgggcagggcgctgatattcaggta acaaccggtaactggaactttatgtttggtgacaacatccagtcgattctggataccaac ctcggttcgttgtttggcctgatgaagcaggaatacacttccacaggcatggcaaaaacc acgtttacctttagtcctaaagacctgccacgccagatcaaaaataaattgctgggggat ctggcaggtgtcagtgcggatactacgttggcggatatctttggtgtggattataccgca gatggcaaaattgtttcccgttcaaaccaacccgttgatggtgttgctatcctgcgtgaa atgctggaaatcatcggtgaattcagcggatcacaactgcaagctttcaccgatcgggaa aaactgcgcgacggcttgagagcagcgctggatctgggagccgacggcgtgaaatctttt gctgaaagccacggactaaaagcggcagcgcctgatgaaaagcaatcagagcatgtttcc atcaatgaagaaaataaacctgtaccgacaaccgaagaattacaggcagaccgggctctt ggacttaactctctgaacctgccaaatctgtttgcaacactattcagtaagaataagcaa acggagatgaaatctcaggtgacgaacctgaaagaaaacctgaccgctgatttgctgaac atacaggataaaactttcgatttcctgcgcaatagcggtcatctgaaaggaaacggtgat atcaacgtttctcttggtaactacaactttaactggggtggtgacggcaaagatctcggt gcctatctgggagaaaacaataacttctggggtggtcgtggtgatgatgtcttttactcc gtaggaacatccaatatctttaccggcggagcaggtaatgataccggtgtgatgatggga cgtgaaaacatgatgtttggtggggcgggcaatgacgttgctgtattggccggacggatt aactacgcctacatgggagaaggtgatgatcaggtctttgcctttggtgaaggcggtatg attgatgctggcaaaggacgcgactatatcgtagcttccggtaactttaatcgtattgag gccggagaagatcaggactacgttgtcaccataggtaacaacaatcaggttgatttggga gaaggtaatgactttgccagggtattcggcaactacaaccggattgacggcaatacgggc aacaattccatcaaactgatgggatatcacgccatgatcaacggtggaaccggtaacgac catctgattgcggatgtggtatccaaattcagccagtttgacggtggtgatggtgatgat ttgctggtgctgggtggatatcagaacagtttcaaaggtggcactggcgtcaatagctat gtggtcagtggtgacgtgattgataacgtggttgaagatatcaagcaaggcgacaagatt atcttcaatgatatcaactggcagaatctgtggttccaacgcagtggttacgatttggtt ctgtcgacccatcgcaatgttaaagatagctcggcacaggggcagtttgaagcgatgggt tctgtcaccttcaataattacttcaatggcaaccgggcggatattatcacccagatgggc gataaagatgcacaaggtgagcgtgaatatacagctctttctgctaatggagtagattcc ttagtgcaggccatgagtgggtttgcgcctaatatgggagacagcggctttattgactcg ctcgatagccaaacgaaatcaactatcgtgaccgcatggtctgatacaacaaacgggaaa tccagacttgcctga

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