KEGG   Xenorhabdus nematophila AN6/1: XNC2_3711
Entry
XNC2_3711         CDS       T03752                                 
Symbol
cysG
Name
(GenBank) multifunctional siroheme synthase: uroporphyrinogen methyltransferase; 1,3-dimethyluroporphyriongen III dehydrogenase; siroheme ferrochelatase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
xnm  Xenorhabdus nematophila AN6/1
Pathway
xnm00860  Porphyrin metabolism
xnm01100  Metabolic pathways
xnm01110  Biosynthesis of secondary metabolites
xnm01120  Microbial metabolism in diverse environments
xnm01240  Biosynthesis of cofactors
Module
xnm_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
xnm_M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:xnm00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    XNC2_3711 (cysG)
Enzymes [BR:xnm01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     XNC2_3711 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     XNC2_3711 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     XNC2_3711 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M MCCD1 Yop-YscD_cpl
Other DBs
NCBI-ProteinID: CEK24705
LinkDB
Position
I:complement(3712195..3713646)
AA seq 483 aa
MDYLPLFVDLKARPVLLAGGGEIASRKASLLLSAGAALTIVAPELHAELQQCHQKGEFEW
LQGTFKTDYLDGIFLVVAATDDHQLNQHIFTEADHRAILANVVDNQPLCSAIFPSIIDRS
PVMVAISSAGRSPVLTKLLREKLESLLPFHLGTMAKIAGNWRERVKQRFLSLRQRRHFWE
KAFHGRFATLVANGQLQQAEEQLEQQLEQTQARAQGELALVGAGPGDPGLLTLKGLQVIQ
QADVVLYDHLVSTEILELVRRDADKICVGKRAGNHSVLQEETNALIIKLAHQGKKVVRLK
GGDPFIFGRGGEELQIAAEAGIPFQVVPGITAAVGASAYAGIPLTHREHSQSVTFITGHC
RENGHELDWPALARGNQTLAIYMGTVKAALISQNLISHGRDPNTPVAVIGCGTRPEQQVL
TGILSELERLAQEAPSPALIVVGEVAQLHHQIAWFGQQSIDQNVIDQEKAGAQVSRPAVI
DLV
NT seq 1452 nt   +upstreamnt  +downstreamnt
gtggactatttacccttatttgttgatcttaaagcccggcctgtgctgctggcaggaggt
ggagaaatcgcttcccgcaaggctagcttgttattgagtgcaggggcggcattaacgatt
gttgcacctgaattacatgcagaactacagcaatgtcatcaaaagggagaatttgagtgg
ctgcaaggaacgtttaaaacagactatcttgatggcatatttttagtggttgcagcgacg
gatgaccatcaactcaatcagcatatttttacggaagctgaccaccgtgcgattttggcc
aatgttgtcgataatcaaccgctttgttccgccatcttcccatcaatcattgatcgttct
ccggtgatggtcgccatctcatcagccgggcgatctccggtattgacaaaattactgcga
gaaaagctggaatccttactcccatttcatcttggcacaatggcaaaaattgccggtaac
tggcgtgagcgagtaaaacaacgttttctctccctccgtcaacgccgccacttttgggaa
aaagcgtttcatgggcgttttgccacattagttgctaacgggcaattacaacaagccgaa
gaacaactcgaacagcaattggagcaaacccaggcacgggcacaaggagagctggcgttg
gtcggtgccgggccgggagaccccgggttgctgacgttaaaaggcttgcaagtcatccag
caagctgatgttgtgctctatgaccacttggtcagtacagaaattctggagctggtgcgc
cgtgatgcagataaaatctgtgttggcaaaagggcaggaaatcattcggttttacaagaa
gaaaccaatgcactgatcatcaaattagcgcatcagggtaaaaaagtggttcgcctgaaa
ggcggagatccgtttattttcggtcgtggtggagaagagttgcaaattgcggcagaagcg
gggatcccgtttcaggttgttcccggcattactgcggcagtaggcgcttccgcttatgcc
ggcattccattgactcatcgagagcactcgcaaagcgtcacctttattacaggacattgc
cgtgaaaatggccatgaattggactggcctgcacttgcacggggtaatcaaactctggcg
atttatatggggaccgtgaaagcggctttgatcagtcagaacctcatttcacatggccga
gatcccaatacccccgttgccgtcattggttgtggtactcgcccagaacaacaagtgttg
accggaatcttatccgaactggaacggttagcacaggaagccccctcacctgccttgatt
gtggtaggagaggtggctcaactccatcaccagatagcatggtttgggcagcagtccatt
gatcagaacgtgattgatcaagaaaaagctggcgctcaagtaagtcgccctgctgttatt
gatcttgtataa

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