Xenopus tropicalis (tropical clawed frog): 100036656
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Entry
100036656 CDS
T01011
Symbol
bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr00280
Valine, leucine and isoleucine degradation
xtr00640
Propanoate metabolism
xtr00785
Lipoic acid metabolism
xtr01100
Metabolic pathways
xtr01210
2-Oxocarboxylic acid metabolism
Module
xtr_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
100036656 (bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
100036656 (bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100036656 (bckdha)
Enzymes [BR:
xtr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
100036656 (bckdha)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
DUF6409
Motif
Other DBs
NCBI-GeneID:
100036656
NCBI-ProteinID:
NP_001090683
Xenbase:
XB-GENE-1007472
UniProt:
A0JPC4
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Position
8:79504991..79513427
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AA seq
291 aa
AA seq
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MGSLHLLGVLMYRGYPLDLFMAQCYGNASDPGKGKQMPVHYGCKDLNFVTISSPLATQIP
QAVGAAYSFKRENADRAVICYFGEGAASEGDAHAAFNFSATLECPVLFFCRNNGYAISTP
TSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIG
HHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMLHKGWWDEEQEKIWRKKSRKMVMEAF
EEAERKHKPKVEHMFSDVYSEMPAQLRKQEESLMKHLKLYGEHYPLDSYEK
NT seq
876 nt
NT seq
+upstream
nt +downstream
nt
atggggtctctgcatcttctaggtgtgctgatgtaccgtggttatcccctggatctgttc
atggctcagtgttatggtaatgcctcagacccaggaaaaggaaaacaaatgcctgtacac
tatggctgcaaggacttgaattttgttaccatctcctctccactggcaactcagatccca
caggctgtgggcgcagcgtattcttttaaacgggaaaatgcagaccgtgctgtcatttgc
tactttggcgagggtgcagccagtgaaggagatgcacatgctgccttcaacttctctgct
actctggagtgccctgttctgtttttttgcagaaataatggttatgcaatatctacacca
acctctgagcaatacaggggagatggtattgcggcccgtggtcctgggtatgggatcatg
tcaatacgagtggatggtaatgatgtgtttgcagtgtacaatgctaccaaagaggcacga
cgcagagcagttgcagagaatcagccattccttatagaggccatgacttacagaattgga
catcacagtaccagtgacgacagctcagcgtaccgctcagttgatgaggttaattattgg
gacaagcaggaccatcctatctctcgacttcgacactacatgttacacaagggctggtgg
gatgaggagcaggagaagatatggagaaaaaaatcacgcaagatggtcatggaagcattt
gaagaggctgaacgcaagcataaacccaaagtggagcacatgttctcagatgtatactca
gagatgcctgctcagttaaggaaacaagaagaatctttgatgaaacatctaaaactgtat
ggagaacattatcctttggacagctatgagaagtaa
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