| Entry |
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| Symbol |
huwe1
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| Name |
(RefSeq) E3 ubiquitin-protein ligase HUWE1 isoform X7
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| KO |
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| Organism |
xtr Xenopus tropicalis (tropical clawed frog)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:xtr00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100126217 (huwe1)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
100126217 (huwe1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:xtr04121]
100126217 (huwe1)
Enzymes [BR:xtr01000]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
100126217 (huwe1)
Ubiquitin system [BR:xtr04121]
Ubiquitin ligases (E3)
HECT type E3
100126217 (huwe1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
8:25154293..25261364
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| AA seq |
4368 aa
MKVDRTKLKKTPTEAPADCRSLIDKLKVCSDEQLLLELQQIKTWNIGKCELYHWVDLLDR
FDGILADAGQTVENMSWMLVCDRPEREQLKALLLAVLNFTALLIEYSFSRHLYSSIEHLT
TLLASSDMQVVLAVLNLLYVFSKRSNYITRLASDKRTPLLSRLQHLAESWGGKENGFGLA
ECCKDMHMSKYPPSATTLHFEFYAEPGSEVKVEKRASSNTLHYIHIEQLDKISESPSEIM
ESLTKMYSIPKDKQMLLFTHIRLAHGFSNHKKRLQAVQARLHAISILVYSNALQESANSI
LYNGLIEELVDVLQITDKQLMEIKAASLRTLTSIVHLERTPKLSSIIDCTGTASYHGFLP
VLVRNCIQAMIDPTMEPYPHQFATALFSFLYHLASYDAGGEALVSCGMMEALLKVIKFLG
DEQDQITFVTRAVRVVDLITNLDMAAFQSHSGLTIFIYRLEHEVDLCRKECPFVIKPKIQ
RPTNVQEGEEMETDMEVSDVAMESCPGPSTSTDHRPSLSTSSSSSSIVVSRTGVQCIPQR
AALLKSMLNFLKKAIQDPAFSDGIRHVMDGTLPTSLKHIISNAEYYGPSLFLLATEVVTV
FVFQEPSLLSSLQDNGLTDVMLHALLIKDVPATREVLGSLPNVFSALCLNARGLQSFVQC
QPFERLFKVLLSPDYLPAMRRRRSSDPLALTSLRSPAGDTASNLGSAVDELMRHQPTLKT
DATTAIIKLLEEICNLGRDPKYICQKPSIQKADGTATAPPPRSNHAAEEASSEDEEEEEV
QAMQSFSTNQQSEVEPSQHVVGTEERIPIPLMDYILNVMKFVESILSNNTTDDHCQEFVS
QKGLLPLVTILGLPNLPIDFPTSAACQAVAGVCKSILTLSHEPKVLQEGLLQLDSILSSL
DPLHRPIEAPGGSVLLRELACAGNVADATLSAQATPLLHALTAAHAYIMMFVHTCRVGQS
EIRAISVNQWGSQLGLNVLNKLSQLYCSLVWESTVLLSLCTPNSLPPGCEFGQADMQKLA
PKEEKATTVLPQGTKRPESEVEGTVVSEEASGLLEGIGLDGDTLAPMETDEPSTSDAKGK
PKITPAMAARIKQIKPLLSASSRLGRALAELFGLLVKLCVGSPVRQRRSHHAASTTTAPT
PAARSTASALTKLLTKGLSWQPPPYTPTPRFRLTFFICSVGFTSPMLFDERKYPYHLMLQ
KFLCSGGHNALFETFNWALSMGGRVPVAEGLEHSDLPDGTGEFLDAWLMLVEKMVNPTTV
LESPHSLPTTKLPGGQNNPQFSALRFLVVTQKAAFTCIKNLWNRKPLKVYGGRMAESMLA
ILCHILRGEPVIRERLSKEREGSREEEGQQDESGARREPQVNQQQLQQVLMDMGFTREHA
LEALLNTSTMEQATEYLLTHPPPLIGGVVRDLSMSEEDQMLRAIAMSLGQDIPMEQRAEL
PEETARRKEEEERKAREKQEEEEAKCLEKFQDAEPLEQDELQGFTDTMLPGCFHLLDELP
DTVYRVCDLIMTAIKRNGADYRDMILKQVVNQVWEAADVLIKAALPLTTSDTKTVSEWIS
QMATLPQASNLATRILLLTLLFEELKLPCARVVETSGILNVLIKLLEVVQPCLQAAKEQK
EVQTPKWITPVLLLIDFYEKTSISSKRRMQMNRYLQANGNNWRWFDDRSGRWCSYSASNN
STIDAAWKAGETCVRFTAGRRRYTVQFTTMVQVNEETGNRRPVMLTLLRVPRLLKSGKNG
NGQELEKTLEEAKEVEAKQKDEKVPEPIPVPETSSTEKDAPTEEPKVGDIVIQGLAEEMV
TVLIRSCVGMLGVPVDPDTLHATLRLCLRLTRDHKYAMMFAELKSTRMILSLTQSSGFNG
FTPLVTLLFRHIIEDPCTLQHTMEKVVRSAATSGAGSTTSGVVSGSLGSREINYILRVLG
PAACRNPDIFTEVANSCIRIALPAPRGSGTASDDEFENLRIKGPNAVQLVKTTPIKPSTL
PVIPDTIKEVIYDMLNALAAYHAPEEVSEKSEQKPVGMNQEVSQILQDMGDEVFQQYRDL
TRQGSDFDGQTSFAINARVFTADSTAAETPQSGTPQGETALTPEENREGLKKDKEGDRSS
EDGKQKAKGSKPLLPTSSILRLLAELVRSYVGIASLIATYNYTAGQSELIKEDCSVLAFV
LDHLLPHTHNAEDKDTPALARLFLASLAAAGSGTDAQVALVNEVKAALGRALAMAESTEK
HARLQAVMCIISTIMESCPSTSSFYSTATTKTQHNGMNNIIRLFLKKGLVSDLARVPHSL
DLSSPNMANTVNAALKPLETLSRIVNQPSSLFGSKGTSGKNKSEADTHGTAQDPNSNQPD
TGETGTEVQEEDPDASHAEVADGDIMDGETETDAVVIAGQPEVLTTQEMQVENELEDLID
ELLERDGAAGNRVGEDESQEDVLMDEPPTNLSQASTLQANREDSMNILDPEDEEEHTQEE
DSSGSNEDEDDSQEEEEEEEDEDDQDDEEGEEGDEDDDDDCSEMELDEDYPDMNASPLVR
FERFDREDDLIIEFDNMFSSATEIPPSPGNIPTTHPLMVRHADHGSLTLGSGTSTTRLAQ
GIGRSQRTLRQLTANTGHTIHVHYPGNRQPNPPLILQRLLGPSAAADILQLSSSLPLQSR
GRARLLVGNDDVHIIARSDDEMLDDFFHDQSTATSQAGTLSSIPTALTRWTEECKVLDAE
SMHDCVSVVKVPIINHLESLRDEELEERREKRRKQLAEEEAKMAEKSKEEKEAKEQNSQG
ANSKQNTPFELSLADQDGSGRPENFPTAPSSAEGTPTSPEIVRLDPTLRATEATLAELTQ
GLPADTGTEDVGQQLMPSHQEDSGPGRPSVEGDATQMELSPAPTITSLSPERAEDSDALT
AVSSQLEGSPMDTSSLASGPLEDGVGEAPGIVNPEQPLVVGSSIAVGQQPVEPPTTCETQ
PVVSQHSDSSQIAPSSELPSTRESAVTLLATDSSGILEEPLPSTSSEEEDPLAGINLPEG
VDPSFLAALPEDIRREVLQNQLGIRPPSRPPPTAAPVIPPPVVANAGVTEVSPEFLAALP
PAIQEEVLAQQRAEQQRRELAQTTTSDTPMDPVTFIQTLPSDLRRSVLEDMEDSVLAVMP
PDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAILRSPAFTSRLSGNRGVQYTRLA
VQRGNTFQMGSSSTHTRPTGSNVDSLLRLRGRLLLDHEALSCLLVLLFVDEPKLNTSRLH
RVLRNLCYHAQTRNWVIRSLLSILQRSSESELCIESPKTSIGGTDKRGAKTSHDNRPLEF
LHKMESKNSNQLSWLSVSMDAALGCRTNIFQIQRSLGRKHTEKHSACGSTVHIHPQAAPV
VCRHVLDTLIQLAKVFPSHFTQQRTKECSVENSDSRERSIKLTCSPCLAPSSSIGASNIS
TDFWDLLVKLDNMNVSRKGKTSIKSVPVSSGSEGESNQCSLEASPLGQLMNMLSHSVIRR
SSLLTEKLLRLLSLISIALPDNKASETAGNQSNSITPAPAPTPATAPAPVPVPAVTVPVV
VSTNIVTTVTTKSGKSPAKSSEVSNAPDKMAASGLTEKQLQLSVEVLTSHSCSEEGLEDA
ANVLLQLSRGDPSTRDTVLKLLLSGAHHLGFTLCKQIGTLLAELREYNLEQQRRAQCEVL
SPDGMPEEQPHSTKPKGKMQSRFDIAENVVIVASQKRPLGGRELQLPSMSMLTSKTSTQK
FFLRVLQVIIQLRDDTRRANKKAKQTSRLGTASLASASSIQAAVQQLEAEADAIIQMVRE
GQRARRQLQTATAEGSARREEQPMDVDQPSPATQEPQSVASEGSQAAEKKEEERLPELPL
LSEQLSLDELWDMLGECLKELEESHDQHAVLVLQPAVEAFFLVHATERESKPPVRDTRES
QLSHIKDEPPPLSPAPLTPATPSSLDPFFSREPSSMHISSSLPPDTQKFLRFAETHRTVL
NQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRRDHV
FEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPG
DRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDM
ESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFGVCEVRDLKPNGANILVTEENKKEY
VHLVCQMKMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKSNT
EYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIH
RDDRSTDRLPSAHTCFNQLDLPAYESYEKLRHMLLLAIQECSEGFGLA |
|---|
| NT seq |
13107 nt +upstreamnt +downstreamnt
atgaaagtggacagaacgaagctgaagaaaacgccaacagaggcgcctgcagattgcagg
tctctgatagacaaactgaaagtctgcagtgatgaacagcttctgctggaactacagcaa
atcaaaacatggaacattggaaagtgcgagctgtatcattgggtagacttgttagatcgc
tttgatggcattctagcagatgctggacaaacggtagagaacatgtcctggatgctggtg
tgcgacagacctgagagggaacagctaaaggctcttctgctagcagtgttaaacttcact
gctttgcttattgagtacagcttctcacggcacctgtacagttccatcgagcaccttaca
actctgcttgcttcttctgatatgcaagtggtcctggctgtgctaaatcttctctacgtt
tttagtaagaggtccaactacatcacacggctagcctctgacaagagaacacctttactg
tcaaggcttcagcaccttgcagagagctggggagggaaagagaatggctttggacttgct
gaatgttgtaaagatatgcacatgtcgaaatacccaccaagcgccacaactttacatttt
gagttttatgcagaacctggatccgaggtgaaagttgaaaaaagggcatccagcaacaca
ctacattatatacacattgaacaattagataagatttctgaaagtccctctgagataatg
gaatctctcaccaaaatgtacagcattcccaaggataaacagatgcttttgtttacacac
atacgactagcacatggcttttctaatcacaagaagcgactacaagctgtgcaggctaga
ctgcatgccatctctatactagtatattctaatgccttgcaagagtctgcaaacagcatc
ctctacaatggtttgatagaggagttagtggacgtgctccaaataacagacaagcaactt
atggaaattaaagctgcatcactaaggaccttgacctctattgtacacttagaaagaacc
ccaaagctgagcagcatcattgactgcactgggactgcctcttaccatggtttcttacca
gtcttagtccgaaactgcattcaagcaatgatagatccaaccatggagccataccctcac
cagtttgcaacagctcttttttccttcctgtatcacctcgccagttacgatgctggtgga
gaagctcttgtttcctgtggaatgatggaagcgcttcttaaggttattaaattccttgga
gatgaacaggaccagattacgtttgtgacgcgagctgtgagggttgttgaccttattaca
aacttagatatggcagcatttcagtcccacagtgggttgaccatttttatttaccgacta
gagcatgaagttgacctatgcagaaaagagtgcccttttgttatcaagccaaaaatacag
cgtcccaccaatgttcaggaaggggaagagatggagacagatatggaagtgtcagatgtt
gctatggagagctgtcctggtccttcgacctccaccgatcaccggccttccctgagcaca
agtagtagctccagtagtatagtggtgtcacgaacaggtgtgcagtgtattcctcaaagg
gctgctctactaaaatcaatgcttaatttcttgaaaaaagcaatccaagatccagctttc
tcagatggcatccgtcatgttatggatggaactcttcctacatcattgaaacacataatc
agcaatgctgaatactatggcccttctttgttcctgcttgctactgaagtggtgacagtt
tttgttttccaagagccctcactgctttcttctcttcaggacaacggcttaacagatgtg
atgctccacgctctccttataaaagatgttcctgctacccgagaagttcttggatctctt
cctaatgtcttcagtgctctctgtttaaatgcccgaggtctgcagtcctttgtgcagtgc
caaccctttgagcgattgttcaaagtgttgctctcacctgattaccttcctgctatgagg
cgacggagaagctcagaccctctagctttgacctctctccggtctcctgcaggcgataca
gcctctaacctgggcagtgctgttgatgaactgatgaggcaccagcccacgttaaaaaca
gacgctacaactgccatcattaagctcttagaagagatatgtaaccttggtagggaccca
aaatacatctgtcagaagccatctattcagaaagctgatggcacggctactgctcctcca
ccacgttccaaccatgcagcagaggaggcttctagtgaggatgaagaggaggaggaggta
caagcaatgcagagtttcagcacaaatcagcaaagtgaagttgaacccagccagcatgtt
gttggcacagaggagaggattcctattcccctaatggattatattctcaatgtgatgaaa
tttgtggaatcaattctaagtaacaacacaactgatgatcactgccaggaatttgtcagt
cagaaggggctccttccacttgtcaccatccttgggcttcccaacctacctattgacttt
cctacctctgctgcttgccaagctgtggcaggtgtctgcaaatccattttgactctttct
catgagccaaaagttctccaagaaggacttcttcagctggattcaattctttcatctctt
gatccacttcatcggcccattgaggctcctggtggctcagtactgcttcgagagttggca
tgtgctggaaatgtggcagatgctactttgtctgctcaagcaactccattattacacgct
ctcactgcagcccatgcctacatcatgatgtttgtgcatacatgcagggttggacagagt
gaaatccgtgccatctctgtgaaccagtggggatcacagctgggtctcaatgttttgaac
aagttgagccagctctactgctcccttgtatgggaaagtacagttttgctgtcactttgt
actcctaacagtttgcctcctgggtgtgagtttggccaagcagatatgcagaaattagcc
ccaaaggaggaaaaggcaaccactgtattgccccaaggaaccaaaagacctgaaagtgag
gttgaaggcacagttgtcagtgaggaagcttcaggcttacttgaaggaattggactggat
ggagatactttagctccaatggaaactgatgaacccagcacttctgatgcaaagggcaaa
ccgaaaataaccccagctatggcggccagaatcaagcaaatcaaaccattactatcagct
tcttctaggttgggccgggctttggcagagctgtttgggttgcttgtcaaactgtgtgta
ggttcccctgttcggcaaaggagaagtcaccatgctgccagcactaccacagcccctaca
ccagctgctcgctccacagcctctgccctcaccaaactgctcacaaaagggctgtcttgg
cagcctccaccctatacccctactcctaggttcagattgactttctttatctgctccgtt
gggttcacatcccccatgctgtttgatgaaaggaaatacccatatcacctcatgctgcag
aaattcctttgctctggtgggcacaatgcactctttgagacttttaattgggcactttca
atgggtggaagagttcctgttgctgagggcctggaacacagtgatcttcctgatggtact
ggagagtttctagatgcttggcttatgttagtggaaaagatggtgaatcctaccactgtg
ctggaatctcctcattcacttccaactacaaagttacctggagggcagaataatccacag
ttcagtgctttacgcttccttgtagtcacacaaaaggcagcttttacctgtatcaaaaac
ctttggaatcggaaacccctgaaagtatatggagggcgtatggcagaatcaatgcttgca
atcttatgtcatatacttcgcggtgagccagttatccgtgagcgtttgagcaaggagcga
gaggggagccgtgaagaggaggggcagcaggatgagagtggagcaagacgggagcctcaa
gtgaaccaacagcaacttcagcaggtgctgatggatatgggtttcacaagggagcatgct
ctggaagctctgcttaacacgagtactatggagcaggccactgaatatctcctcacccac
cctccacctcttattggcggagttgtacgggacttaagtatgtcagaggaagatcagatg
ctgagagccattgccatgtcgctgggacaagatatccctatggaacagagggcagaactg
cccgaggaaactgctcggcggaaagaagaggaggaacgcaaggcacgagaaaaacaagag
gaagaggaagctaaatgcttggaaaagtttcaagatgcagaacccctggaacaggatgag
cttcaaggattcacagacaccatgctccctggctgcttccacttgcttgatgagctgcca
gacacagtctatagagtgtgtgatcttataatgactgccataaagcgcaatggggcagac
tatcgagacatgattctaaaacaagtggttaaccaggtatgggaagccgctgatgttctt
attaaagctgcactgccgctgaccacaagtgacacaaaaactgtgtctgagtggatcagc
caaatggctactcttcctcaagcttctaacttggccactcgcatccttttgctcacactg
ctgtttgaggagctaaaactgccatgtgctagagttgttgaaacaagtggaatacttaac
gtactaattaagctgcttgaagtggttcagccatgtttgcaggcagccaaggagcaaaag
gaagttcagacaccaaagtggattacaccagtcctcctcttaatagatttttatgagaag
acctcaatttcttctaaaagaagaatgcaaatgaacaggtaccttcaagctaatggaaac
aactggcgatggtttgatgatcggtctggccgttggtgcagctacagtgctagtaacaac
agcactattgatgcagcctggaaagcaggagaaacatgtgtgcgatttacagctggccgt
cgaagatatactgtgcagtttaccacaatggttcaggtaaatgaagagaccggcaataga
cgacctgtcatgctgactctcttgcgtgttccgagacttttaaagagtggaaaaaatgga
aatggacaggaacttgaaaagacacttgaggaggcaaaggaggttgaagcaaagcaaaaa
gacgaaaaagtgcctgagcccattccagttcctgaaacctcttccactgagaaagatgca
ccaactgaagagcccaaagttggagacatagtaattcagggtctggctgaagaaatggtg
accgtccttatacgttcctgcgtcggcatgcttggtgttcctgttgatccagatactctt
catgcaaccttgcgtctttgcctgcgtctcacacgtgaccacaaatatgccatgatgttt
gcagagcttaagagcactcgaatgatcctcagcttaactcaaagctctggattcaatggc
tttactccccttgtgacgctcctatttaggcacatcatagaggatccttgcaccctccag
cacaccatggaaaaggttgtacggtctgcagcaactagtggggcagggagtaccacatct
ggggttgtgtctggaagcctgggttcgcgtgaaatcaactatatacttagagtactgggt
ccagcagcttgtcgaaaccctgacattttcactgaagtggcaaacagttgcattcgcatt
gctctccctgcacctcgtggatctggaactgcctctgatgatgagtttgagaaccttcgg
atcaaaggtcctaatgcagttcagttggttaaaaccacccctataaagccctccaccttg
ccagtcatccctgatacaattaaggaagtaatctatgacatgctgaatgcactggcagct
taccacgcccctgaggaagtatctgaaaagtctgagcaaaaacctgttggcatgaaccag
gaagtcagccagatcctacaggacatgggtgatgaggttttccagcaatatcgggactta
accagacagggaagcgactttgatggtcagaccagttttgccatcaacgcgcgagtcttt
actgctgacagcacagctgccgaaacacctcagtctggtacacctcaaggtgaaactgcc
ttaacacctgaagaaaaccgagaagggttaaagaaagataaggaaggagaccgtagttca
gaagatggaaagcagaaggcaaaaggtagtaagcctttgctgcctacctcttccattctt
cgactacttgctgaacttgtcaggtcctatgtcggaatagcctcgctgatcgccacctac
aattacactgcaggacaatctgaactaattaaagaggattgcagtgtattggcgtttgtg
ctggatcacctgctaccccacacacataatgcagaggacaaggacacaccagccctagcc
cgcctcttcttagccagccttgctgcagcaggaagtggcactgatgcccaggttgcacta
gtgaatgaagtaaaggcagctcttggcagagccctagcaatggctgagagcacggagaag
catgctaggttgcaggctgtgatgtgcattatcagtaccattatggagtcatgtccatcc
acctccagcttctacagcacagcaaccaccaaaacccagcacaatggcatgaacaacatc
atcagactctttttgaaaaaggggctggttagtgatttagccagggtccctcacagcctt
gatttatccagtccaaatatggcaaacaccgtgaatgcagcactgaagccactcgagaca
ctgtctcgcattgtcaatcaacccagcagtttgtttggaagcaaagggacttcaggaaag
aataaatctgaggcagatacacatggaacagcccaggatcccaacagtaatcagccagat
acaggtgaaacaggaacagaagtgcaggaagaggacccagatgcttctcatgctgaagta
gctgatggagacatcatggatggagagacagagactgatgctgtggttattgctggccag
cctgaagtccttactacacaagaaatgcaggtagagaatgagcttgaagatctgatagat
gaacttcttgaaagggatggtgctgcaggtaaccgggtcggagaagatgaatcacaggaa
gatgtgctgatggatgagcctcctactaacctcagccaagcctccactcttcaggctaat
cgagaagactctatgaacatcttagacccagaggatgaggaagagcacacccaagaagag
gacagcagtggcagcaatgaagatgaagatgacagccaggaagaggaggaggaagaggaa
gatgaggacgatcaggatgatgaggagggtgaggaaggggatgaggatgatgatgatgac
tgttcagagatggaactggatgaggattatccagacatgaatgcctcacctcttgtacgc
tttgaacgttttgacagagaagatgatttaatcatagagtttgataacatgttctccagt
gccactgagatccctccatcccctggtaacatccctactacacaccccctaatggtgcga
cacgctgatcacggctccttgactcttggcagtggcacttccactactcgcctggcacag
ggcatcgggcgcagccagagaacactccgacaactcacagccaacaccggtcacacaata
catgttcattatcctggcaacaggcagccaaatccacctttaatcctccagaggttgctg
gggccctcagccgctgctgacatcttgcaactaagcagcagtcttcctctgcagagtcgt
ggccgagcacgtctacttgttggcaacgatgatgtccacatcatagcacgctctgatgat
gagatgcttgatgattttttccatgatcagagtacagccacaagtcaggctggcacactt
tccagcattccaactgcgctgacccgctggacagaagagtgtaaggtcttggatgctgaa
agcatgcatgactgtgtatctgtggtcaaagtcccaatcatcaatcatttggaatctttg
cgtgatgaggagcttgaggagcgcagggaaaaaagaaggaaacaactagcagaagaggag
gccaagatggcagagaaatccaaggaggagaaggaagcaaaggagcaaaattcacagggt
gccaattcaaagcagaataccccatttgaactgagccttgcagatcaagatggaagtggt
cgtcctgaaaatttcccaactgcaccatcttctgcagaaggaactccaacaagtcctgaa
attgttcgtttagatcccaccctaagggctactgaggctactctggcagagctgactcag
ggtctgcctgctgatacaggcacggaggatgttgggcaacaactcatgccatctcaccaa
gaggactctggaccaggacggccaagtgtagagggggatgccacacaaatggagctatcg
ccagcacccactataacctccttatcaccagagcgagcagaggattcagatgctttgaca
gctgttagtagccaactagagggctcgcctatggacaccagcagtcttgcctctgggccc
ttagaggatggcgtaggggaggcacctggaattgttaatccagagcagcctcttgtggtt
ggcagtagcattgctgttggacagcaaccagtggaaccaccgacgacctgtgaaacccaa
ccagtagtttctcaacacagtgatagctcacaaattgccccttcctctgagttgccttcc
acaagagaaagtgctgtgaccttgttggctacagattctagtggtatccttgaagaacct
ttgccttctacaagcagtgaagaggaagacccattagcaggcataaatcttccagagggt
gtggatccttctttcctagcggctcttcctgaagacatccgcagagaggtgctgcagaat
cagttgggcatacggccgccatcgcgacctccacccactgctgccccagttattcctcct
cctgtggttgctaatgctggtgtcacggaggtcagccctgagttcttggcagcgttgcca
ccagccattcaggaagaggtcctagcacagcagcgagcagaacagcagaggcgggaactt
gctcagaccactacgtctgatacacccatggatcctgtgactttcattcagacgttacct
tctgatctacgtcgtagtgtgttagaagacatggaggacagtgttttagctgtgatgcca
cctgacattgctgcagaggcacaggctctaaggcgagagcaagaagctcggcagaggcaa
ctaatgcatgaacgactgttcgggcacagtagcacatctgcactctctgccatccttagg
agtcctgctttcacgagtcgcttgagtggaaaccgaggtgttcagtacacacggttggct
gtacagagagggaacactttccaaatgggaagcagcagtacacataccagaccaaccggt
agtaatgttgacagcctactacgattacgaggccgactattacttgatcatgaagccctc
tcctgtctgcttgtcctactgtttgttgatgaacccaagctaaacaccagtcgcttgcac
cgtgttctacgcaacctctgctaccatgcacaaacaaggaactgggtgattagaagcttg
ttgtctatactgcagcgtagcagtgaaagtgagctttgtatagaaagcccaaagacttct
attgggggcactgataaacggggtgcaaaaacaagtcatgacaaccgccctttagaattt
ctgcataagatggaatcgaagaattccaaccagctctcctggctttctgtatccatggac
gctgctcttggctgccgtacgaacatcttccaaatccagaggtccctaggacgcaagcat
acagaaaagcattcagcctgtggttctactgtccacatccatccccaagcagcccctgta
gtgtgtagacatgtgcttgacacactaatacagctagctaaggtgtttcccagtcatttc
acacagcagcgaaccaaagaatgtagtgtggaaaacagtgacagcagggagcggagtata
aaacttacttgtagtccgtgtcttgcaccatctagtagtattggagcaagcaacatctcc
acagatttctgggacttgctagtcaagctagacaacatgaatgtgagccggaaggggaaa
acgtctataaaatctgtgccagtgagctctggttctgaaggcgagagcaatcagtgcagc
ctggaggcctcccccttaggacagcttatgaatatgctgtctcattctgttattcgccgc
agttcgctgcttactgaaaagctgctgagacttctctcccttatctctattgcccttcct
gataataaggcttctgaaacagcaggcaatcagagcaattctattaccccagcacctgca
cctacgcctgcaactgcaccagcccctgtgcctgtacctgctgtaacagttccagttgtt
gtgagcacaaacatagtgacaactgttacaaccaaaagtggaaaatctcctgcaaaatca
agtgaagtcagcaatgcaccagataagatggcagcttctggccttacagagaaacagctg
cagttgtctgttgaggttctgacatcacactcgtgttcagaagaaggactggaggatgcc
gccaatgttctacttcagctttccagaggcgaccccagtacacgggacactgtactgaaa
cttctgcttagcggagcacatcacttggggtttactctctgcaaacagataggtacacta
ctagcagagctccgggaatataacctagagcagcagcgtcgtgcacagtgtgaagttctt
tctccagatggtatgcctgaggagcaaccccacagcacaaagccaaaaggcaaaatgcag
agcaggttcgacattgcagagaatgtggtgattgtggcttcccaaaagcgtccactggga
ggaagagagctgcagctcccctcaatgtctatgctgacgtcaaagacttccacacaaaaa
ttctttcttcgagtgctgcaggttatcatccagcttcgcgatgacactcgcagagccaac
aagaaggccaagcagaccagcagattaggcactgccagtctggcctcggctagcagcatc
caagcagctgtgcagcagctggaggctgaggctgatgccattatacaaatggtacgtgag
ggtcaaagggcgcggagacagctgcaaactgcaacggcggagggttctgctcgcagggag
gagcagcctatggatgttgaccagccttcgcctgctacacaggagcctcagtcagttgct
tctgaaggttctcaggctgctgaaaaaaaagaagaggagaggttaccagagttaccgctg
ttaagtgagcagctaagtttagatgagctgtgggacatgttgggagagtgcctgaaggaa
cttgaggaatctcatgaccagcatgccgtattagtgttacagccagccgtagaagccttt
ttccttgttcatgcaacagagcgggagagcaagcctcctgtgcgggacactcgggaaagc
cagttatctcacattaaggatgaaccacctcccctgtctcctgcacccctcactccagcc
acaccttcttccttggatcctttcttctctcgtgaaccttcatctatgcacatttcctct
agtttgcctcctgacactcagaagttcctaagatttgctgagactcatcggactgtatta
aatcagatccttcgccagtccaccacacacctagctgatgggccctttgctgtgcttgta
gactatatcagagtccttgactttgatgttaagcgcaaatatttccgacaggagttggag
cgactggatgaagggctaagaaaagaggatatggcagtgcatgtgcggcgagatcatgtg
tttgaggattcctaccgggagctgcaccgcaaatcccctgaagaaatgaagaatagattg
tacatagtatttgaaggagaagaagggcaggatgcaggtgggctgcttcgggagtggtac
atgattatctccagggagatgttcaatcccatgtatgctttgttccgcacttccccaggt
gaccgcgtcacctacactattaatccttcctcccactgtaaccctaaccacctcagctac
ttcaagtttgtgggccggatagttgccaaagcggtttatgacaaccggctactggagtgt
tacttcactaggtccttctacaagcatatattgggcaagtctgtcagatacacagacatg
gagagtgaagattatcacttctatcagggtctggtgtacttgcttgaaaatgatgtctcc
acactgggatatgacttgactttcagcactgaggttcaagaatttggtgtctgtgaagtc
cgagacctaaaaccaaacggtgcaaacattctggtaacagaagaaaacaaaaaggagtat
gttcatcttgtgtgccagatgaagatgacaggtgcaatacgtaagcaattggctgccttc
cttgagggattttatgagataatccccaaacgtctgatctccatcttcactgagcaggaa
ttggaactgcttatctctggccttcccaccatagatattgatgacctaaaatcaaacact
gagtatcacaaataccagtctaactccatccagattcagtggttctggagagcgttgcgc
tcattcgatcaagctgaccgggcaaagttccttcagtttgttactggaacttcaaaggtc
ccattacagggttttgctgcgctggaaggaatgaacggcatccagaaattccaaatccac
agagatgatagatctacagacaggctgccttctgcgcacacgtgcttcaaccagttggac
cttccagcctatgagagttacgagaagctacgtcacatgctgctgttagccatccaggag
tgctctgagggctttggccttgcctag |
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