Xenopus tropicalis (tropical clawed frog): 100216307
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Entry
100216307 CDS
T01011
Symbol
eif2ak4
Name
(RefSeq) eIF-2-alpha kinase GCN2
KO
K16196
eukaryotic translation initiation factor 2-alpha kinase 4 [EC:
2.7.11.1
]
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr04140
Autophagy - animal
xtr05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100216307 (eif2ak4)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
100216307 (eif2ak4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xtr01001
]
100216307 (eif2ak4)
Enzymes [BR:
xtr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100216307 (eif2ak4)
Protein kinases [BR:
xtr01001
]
Serine/threonine kinases: Other
PEK family [OT]
100216307 (eif2ak4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RWD
HGTP_anticodon2
tRNA-synt_His
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100216307
NCBI-ProteinID:
NP_001243855
Xenbase:
XB-GENE-967321
UniProt:
A0A8J0QES6
LinkDB
All DBs
Position
8:107784120..107825330
Genome browser
AA seq
1668 aa
AA seq
DB search
MAGGRGNALLPIELSPQGGLRPTPPACDPPETYSHRQENELEVLESIYSGDFADLRKNSA
WKVQQPPEVIIALRPQGNEVHVKVDLWVKCPQNYPDVPPEIKLKNIQGLSNENVNSLTSS
LEDLAKQLCGEVMIYQLADHVQCFLTEYNHPPPKSFHEEMLKNLQKQQEKLALEEERRMQ
EIKMKEEQTRREILNEIQKREEEKKEEKRRKEVAKQERIENANLMCQENVNKINNTGKTT
TAASDGSLPDHGGTNRNRPHSAGRSKRDRQYSVCLTDDSTPFEVLTFDIGCSGQIVVHRG
KCLGKDELLGKSVYNGLETASGHFVVIYEWVLQWQKKMGKFLTNQEKEKIEKCKKQIQGT
ETEFSSLIKLSHPNIVHYLAMRIKEKEDSISVGIIAEHVNGTKLSSYLEQGVPVPLDQLR
HYTAQLLSALDYLHSNSVVHKVMCASSVLVTADGKVKLTDYSLSKRLADICKEDVFEQTK
VRFSEDALPSKSGKKGDIWKLGLLLLSLSQGNIAKEYPVKVPSDLPADFQDFLQKCVCLE
DKERWTTQQLLSHSFLNPPPEKSPVTEECSDDYPGDCTETVIPRSSVSNSTFHIESQRQF
SRYFNEFEELQMLGKGAFGAVIKVQNKLDGCYYAVKRVQINPASKQFRRIKGEVTLLSRL
NHENIVRYYNAWIEKHEHPTISPKCEAHEEKKVTVKPEQIVKNDLGLLDDIEENAPAPIL
TSSVEWSTSCERSSSAHCTNGDQDSSDDDDDDDEEGVFSPSFLPGTDSDSEIIFENEDDI
SPDQNNVEDRKAGANEIVTQAVHYLYIQMEYCEKSTLRDTIDQGLYMDVGRLWRLFREIL
DGLTYIHEQGMIHRDLKPVNIFLDSEDHVKIGDFGLATDHPASYTESAQGEEDQAHSDLV
KVDPEDRASTPGRNTQGKLTGMVGTALYVSPEVQGNTKASYNQKVDLYSLGIILFEMSYR
PMDTSSERISVLSRLRQALIVFPSDFENPENEKQKKVITWLLNHDPASRPTAMELLKCDL
LPPPQLEESELHEVLHHTLANIDGKAYRTMMSQIFAQRISPAMDYTYDSDILKGIFSVRS
ARLHHHVCEAVCRIFKRHGAVKLHAPLLMPRGKAGFDNSESACFMDHSGMLVTLPYNLRI
SFARFVARNNITSLKRYSIERVFRPRKLNRCHPKELTECAFDIITSAANCYLPIAETIYT
IYEIIQEFPVLQERNYSIYVNHTSLLKAILLHCGVPEDKLTQVYNILYDAMIEKLTKREV
EAKFCNLSLSENSFQLSRLYRFIEQKGDLPDLEAMMVPLTKQKTGVGVLAKQGLKDLEGV
IGLVKRLGIKLQIVVNFGLVYKMQQHSGIVFQFVAFIKRRQRTVPEILAAGGRYDHLISQ
FRGPQTGAMGLPCAVGVSIAIDKISAALSTAEEHISSCDLLVVSAGQMSLNRAIGITQKL
WAAGITAEIMYEWSESQDELQDYCKCSGISYAAIISDKEGNHIKLKTFEKERQSEKRILE
SDLVDLLVQKLRIRVLEERNNRETSDSLSVQNVKGSFNSQSQFEPHSAIIVPSVSVIAPE
KLSASARRRFETQVLTKLQTLITNFQQRNGEIEILAVDLPKETIQNLLALECADEQVFNA
SVKMLMSRLPKQRYLKSVFDEIYTIKIEKRVPVLVLYSYKDDYYKILF
NT seq
5007 nt
NT seq
+upstream
nt +downstream
nt
atggcaggcggccggggaaatgcacttcttcctattgagctcagcccgcaagggggtctg
cgccctactccgcctgcctgtgacccccctgaaacttattcccaccggcaggagaatgag
ctggaggtcctggaatccatctatagtggggatttcgcggatctgcgcaagaactctgcc
tggaaggtacagcagcctccagaagtcatcattgccttacgtcctcagggaaatgaggtt
catgtcaaggtggatttatgggtaaaatgccctcagaactatcctgatgttcctcctgaa
ataaagctgaagaacatccaggggttgtccaatgaaaatgtgaactctctgacatcaagc
ttggaagatttagcaaaacagctttgtggagaggtaatgatataccagcttgcggatcat
gtgcagtgttttcttacagagtataaccatccacctcctaaatcctttcatgaggagatg
ttaaaaaaccttcagaagcagcaggagaagcttgctcttgaagaagagagacgaatgcaa
gagataaagatgaaagaagagcagacgagacgggaaatccttaatgaaatccagaagcga
gaagaagagaaaaaggaagaaaaaagaaggaaggaagtagcaaaacaggaacggattgaa
aacgctaatctaatgtgccaagagaatgtaaataagattaataatacaggcaagacaaca
acagctgcctcggatgggtcacttcctgatcatggaggaaccaacagaaatcggccacat
tcagcaggacgctcaaagcgggaccgacagtattcggtgtgcctcactgatgactcaacc
ccatttgaagtgttaacctttgatattggatgcagtgggcaaattgttgttcacagagga
aagtgcctggggaaagatgagctgctgggtaaatctgtttacaatggcttggaaactgct
tcaggacattttgttgtaatctatgaatgggttctccagtggcagaaaaagatgggcaag
tttcttactaatcaagaaaaagaaaagattgaaaagtgtaaaaaacagattcagggaaca
gaaaccgagttcagttctcttatcaaactgagccatccaaacattgtgcactacctcgct
atgcgaataaaagagaaagaagattccatttctgtcgggatcatagctgaacatgttaat
ggtacaaagctttccagttaccttgagcagggtgtacctgttccactggatcaactacgg
cactatactgcccagctgctatcggcactggactatttgcattctaattctgtggtacat
aaagtcatgtgcgcctccagtgttttggtgacagctgacgggaaagtaaaactgacagac
tatagcctttccaaacgccttgctgacatctgcaaagaggacgtgtttgagcaaacaaaa
gttcgattcagtgaggatgctctgcctagcaagagtggcaagaaaggagatatatggaag
ctcggtctcttgctactttcgctgtcacaaggcaacatagccaaagagtatcctgtaaaa
gtgcccagtgacctgcctgcagatttccaagatttcctgcaaaagtgtgtttgcttggaa
gacaaggaacgctggactacacagcagttactaagtcacagtttccttaaccctccacct
gagaagagtcctgtaacagaggaatgctcagatgattatccgggtgactgtactgagact
gtcattcccagatcttcagtatctaattccacattccatattgagtcacagagacagttt
tctcgctacttcaatgagtttgaagaattacagatgcttgggaaaggggcatttggtgct
gtcattaaggttcagaacaaactggatggctgctattacgctgtaaaacgggtacaaatc
aatcctgcaagtaaacagttccgcagaattaagggggaggtaacattgttatctcggctc
aaccatgaaaacattgtaaggtactataatgcatggattgagaaacacgagcatcctact
atttctcctaaatgtgaagcacatgaggaaaagaaagtgactgtgaagccagaacaaata
gtaaagaatgatttgggattgttggatgatattgaggaaaacgcaccagcacccatatta
accagctctgtagaatggagtacatcttgcgagcgatcatccagtgcgcactgtactaat
ggggatcaagattcaagtgatgatgatgatgatgacgatgaagagggagtgttttcacct
tcgttcctgcctgggacagattctgacagtgagatcatatttgagaatgaagatgacatt
agtccagatcagaacaatgtagaagaccgcaaagctggagccaatgagattgtgactcag
gcagtgcattatttatatattcagatggaatattgtgagaaaagcaccttacgggacacg
atagaccaaggactgtatatggatgttggccgcctctggaggctgtttcgtgaaattttg
gatggattgacctatatacatgagcagggaatgatccacagagacctaaagccagtcaat
atctttttagattcagaagatcatgtcaaaataggagattttggactagctacagatcac
ccagcatcttatactgaatcagcacaaggggaagaggatcaggcgcattctgacttggtt
aaagtcgaccctgaagatagggcctcaacacctggtcgcaatactcaaggaaaactcact
ggcatggttggcactgccttgtatgtaagccctgaagtccaaggaaacaccaaagcttca
tataaccagaaagtggacctttacagcctgggtataatattgtttgagatgtcctaccgg
cccatggacacaagttctgaacgtatctctgtcttaagcaggcttagacaggccttgatt
gtgttcccaagtgattttgaaaacccagaaaatgaaaaacagaaaaaagtgattacttgg
ctcctgaaccatgacccagcatcccgccccaccgctatggagttgcttaagtgcgatctc
ttacccccaccacaactagaggagtctgaactccatgaagtcctgcaccacaccttggcc
aatatcgatgggaaagcgtaccgcacaatgatgagtcaaatctttgcccagcgcatttca
cctgctatggattatacatatgacagtgatatattgaagggtattttctcagtccgttct
gccagactacatcatcatgtttgtgaggcagtctgcaggatatttaaaagacacggggct
gtgaagttacatgccccactgctgatgccacgaggtaaagctgggtttgataacagtgaa
tctgcatgttttatggatcacagtggcatgctggtcacccttccttataacctcaggata
tcatttgcgcggtttgttgcaaggaataatataactagtttgaaaaggtatagcattgag
agagtgtttagaccacgcaaactgaaccgctgccatccaaaggaactcactgagtgtgca
tttgatataatcacttctgctgcaaactgttacctgcccattgcagaaacaatatacacc
atatatgaaattatccaggaatttccagtactgcaggaaaggaattacagtatttatgtg
aaccacacctcgttgttgaaagccattctccttcactgtggcgtgcccgaggataaactc
actcaggtgtataacattctgtatgatgcaatgattgagaagctgacaaaaagagaagtg
gaagccaaattttgtaatctctccctttcagagaacagtttccaattgagtcgcctttac
cggtttattgagcagaaaggagacctcccagatttggaggcaatgatggtcccactcaca
aagcaaaaaacaggggtcggtgtgctggcaaagcaaggtttgaaagacttggaaggagtc
attggattagtgaagaggctgggcattaaattacagattgtggttaactttggacttgtc
tacaagatgcagcagcacagtggcatagtcttccagtttgtggcttttatcaagcggaga
cagaggactgtgcctgaaatacttgcagctggaggcagatatgaccatttgatttcccag
tttaggggacctcagactggagctatgggattaccctgtgctgtaggcgttagtatagca
atagacaagatatctgctgcgctttccactgcagaggaacatatcagcagctgtgattta
ttagtcgtaagcgctgggcagatgtctctgaatagagccattgggataacacagaagctg
tgggctgctggcattactgcagagatcatgtatgagtggtctgagtctcaggatgaactg
caggattattgcaagtgttcggggatttcgtatgctgcaattatttctgacaaagaagga
aatcacattaagctgaaaacatttgagaaggaaagacagagtgagaagagaatattggaa
tctgatctagtggatctcctggtgcagaaacttcggatcagagtccttgaagaaagaaat
aacagagaaacgtcggacagtctctcagtgcaaaatgtgaagggctcgtttaattcccag
agtcagtttgagccacacagcgcaataattgtgccaagtgtcagtgttatagcaccagaa
aagctatctgccagtgccaggcggagatttgaaacccaggtgctaacaaagcttcagaca
ctcattacaaacttccagcagagaaatggtgaaattgaaattttagcagttgatctgcca
aaagaaacaatacagaacttgttagctttagagtgcgcagatgaacaagtcttcaatgca
tcagtgaaaatgctaatgtctcggctgccaaaacagagatacctgaaatcagtgtttgat
gaaatatacaccattaaaatcgaaaagcgggttcctgtgctggtactatacagttataaa
gatgattattacaagatccttttttag
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