Xenopus tropicalis (tropical clawed frog): 100489432
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Entry
100489432 CDS
T01011
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr04217
Necroptosis
xtr04620
Toll-like receptor signaling pathway
xtr04621
NOD-like receptor signaling pathway
xtr05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100489432 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100489432 (tyk2)
04621 NOD-like receptor signaling pathway
100489432 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
100489432 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xtr01001
]
100489432 (tyk2)
Enzymes [BR:
xtr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100489432 (tyk2)
Protein kinases [BR:
xtr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100489432 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
Kinase-like
Kdo
RIO1
ABC1
FERM_C_FAK1
CttA_N
Motif
Other DBs
NCBI-GeneID:
100489432
NCBI-ProteinID:
XP_002939720
Xenbase:
XB-GENE-993652
UniProt:
A0A6I8QQ90
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All DBs
Position
3:complement(137608908..137647960)
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AA seq
1179 aa
AA seq
DB search
MALCQCAVKHSESDMDGCSFTPAGLRVFLYWSNGKEHYVTYSQGEITAEDVCIHISERLG
ITPLCYTFFALYDVHGKYWYPPDHVFTVTKDMKLFLHFRMRYYFRNWHGMNEKEPVVFRN
VPKSRDGSEDRSRIEQAGAILDLASFEYLFEQGKFDFVNDVVSLKDFSMEQDIHRFKNES
LGMAVLHLSHIAIKKKVSLEEVAKQISFKECIPKSFCRQIQQNNYLTKFRMKNVFKKFVR
RFHLHTVSPGKLNEEDIMYKYLSTLENLAPRLGCEVFKALSLELPAEGEKLPFYLNGGYM
EHTDTVNREPTSTHQVMVSGMEGIQYRISKEEEDTETSTQRHYFSKKSRVKGQKALKSQQ
LPGKSEPKWVTFCDFQDITHIVISKSRVSVSCQDNRCLEIALHSCEDALSFVSLVDGYFR
LTTDSNHYLCHEVAPPRLVLSVANGIHGPLQEQYVAQKLKREEQEEGLYIIRWSAFSFNI
IIMAVKSVTQSKGFTYKQFKIEKKGGVFSLEDWDREFHSVKELVESLRGCTLKSGKDTFT
VKKCILPKSGEVSNLTISRRGKNNRERTVSKNLNLSQLSFHQIRKHEILQKSHLGQGTRT
NIYDGMLLVTEGSEHESDYESGELNNNSHDLRVVLKVLDPSHRDIALAFFETASLMSQVS
HIHLVFVHGVCVRESENIMVEEFIEHGPLDVCLRKDKLKIKAEWKFTVARQLASALSYLE
DKNLVHGNVCAKNILLARKGLEENSSPFIKLSDPGVTFTVLSREERVERIPWIAPECVRN
ISSLSTTADKWSFGTTLLEICFNGEVPLKERTPPEKERFYEKELGLPEPSCKELADLIGQ
CHNYNPEGRPSFRTILRELTQLQPDVLPDIATISPVSITDPTVFQKRYLKKIRELGEGHF
GKVSLYCYDPNNDGTGEMVAVKSLKSGCSQQLESSWKGEIKILKTLYHENIVKYKGCCSE
QGDKIVQLIMEYVPLGSLRDYLPKHNVSLAQILLFAQQICEGMAYLHSQHYIHRDLAARN
VLVENENVVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYATECLKECKFFYASDVWSFG
VTFYELLTRCDSYLSPPSKFIEMIGVTQGQMTVVRLIDLLERGQRLPCPSDCPLEIYKLM
KNCWETEANFRPTFNHLIPILKSFVNTYSTQAPSVFSLC
NT seq
3540 nt
NT seq
+upstream
nt +downstream
nt
atggctctttgtcagtgtgccgtgaaacacagtgagtcagacatggacggctgcagcttc
accccggccgggctcagagtctttctctattggagcaatggcaaggagcactatgtcacg
tatagccagggagagatcacggccgaggatgtctgcatccacatatcagagaggcttggg
atcacacctctttgttacacattttttgctctttatgatgtgcatggaaaatactggtat
cctcccgaccatgtgtttactgtcacaaaggatatgaaactgtttctccattttcgcatg
aggtactatttcaggaactggcatggtatgaatgagaaggagcctgttgtttttcgcaat
gttccaaagagcagagatggcagtgaggacaggagccgcattgagcaggcaggagctatc
ctggatttggcttcttttgaatacctttttgaacagggaaagtttgactttgtgaatgat
gtggtgtccctgaaggatttctcgatggagcaggatatccacagatttaagaacgagagt
cttggcatggccgtgcttcacttgtctcatatcgccataaagaagaaagtgtctctggaa
gaggtggcaaagcaaattagcttcaaggagtgcatcccaaagtcattctgccgccaaatc
cagcagaacaattacctcaccaaattccgcatgaagaatgtgttcaagaaattcgtccgc
cgtttccaccttcataccgtaagccccggaaagctgaacgaggaagacatcatgtacaag
tacttgtcaaccttggagaacttggcacctcgcttaggctgcgaggttttcaaggcattg
tcattggaactgccagccgagggagagaagctgccattttacttaaacgggggctacatg
gaacatacagacactgtgaacagggaaccaaccagcactcatcaggttatggtgagcggg
atggaaggaatccaatacagaatcagcaaagaggaggaggacactgaaaccagcacccag
agacattacttcagcaagaaaagccgggtaaaaggccagaaggcattaaagtcccagcag
cttccaggaaagagcgaacccaaatgggtgacattttgtgactttcaggatatcacgcac
attgtcatcagcaagagcagagtcagcgtcagctgtcaggataaccgctgtctggagatt
gctctgcattcctgtgaagatgccttgtcgtttgtatcgctggtagatggatattttagg
ctgacaactgattctaaccactacctttgccacgaggtcgcccccccacgtttagtgttg
agcgtggcaaatggaattcatggacccttgcaggagcagtatgttgcccagaagctgaag
cgagaggagcaggaggagggactgtacattattagatggagtgccttcagtttcaacatc
ataatcatggctgtaaagagtgttacccagagcaaagggttcacctacaagcagttcaag
attgagaagaagggtggagtgttctcactcgaggattgggatcgtgagttccacagtgta
aaagaattagtggaaagtcttcggggctgcaccctgaaatctggaaaggacacctttaca
gtgaagaagtgcatcttgccaaagtctggagaagtttccaacttgactatctccaggaga
gggaagaacaatagggagagaacagtgtccaagaacctcaatctgagccaactcagtttc
caccagatccgcaaacacgagattttgcagaaatcccacctagggcagggcactcgcact
aatatttatgacgggatgctcctggtgaccgaaggaagtgagcacgagtctgattatgag
tcaggggaactgaataacaattctcatgatctgagggtggttctgaaagttctggatccc
agccacagagacatagcgctggctttctttgagacggcaagtttaatgagccaggtctcc
cacatccatcttgtgtttgtccatggagtttgtgttcgagagtctgagaatatcatggtg
gaagagttcattgaacacggacctctagatgtttgtttgcggaaagacaaattaaagatc
aaagcagaatggaagttcactgtagccagacaactagcaagcgccttgagctacctggaa
gataagaatttggttcatggaaatgtctgtgcaaaaaatattctgctggccagaaagggt
ttggaagagaactcctctccgttcatcaaactgagtgatcccggagtgacattcacagtc
ttgtccagagaagaacgtgtggagaggatcccatggattgcgccagagtgtgtccgaaac
atctctagtcttagcaccaccgctgataaatggagctttgggacaaccctgctggaaata
tgttttaatggagaagtccctctgaaagaaaggacgccccctgagaaagagcgtttttat
gagaaagagctgggtcttccagagccttcctgcaaggagcttgctgaccttattggccag
tgccacaattacaacccagagggaagaccctcttttcgaacaatcctcagagagctgact
cagctgcagcctgacgttcttccagacattgccaccatcagcccagtctccatcacggat
cccacagtgtttcagaagcgctacctgaaaaaaatcagagagctgggagagggccacttc
ggcaaagtcagcctctactgctacgaccccaacaacgatggcacgggagaaatggtggct
gtgaagtccctaaagtctggctgcagccaacaactggaatccagctggaaaggagagatc
aagatcctgaagactctttaccacgagaacattgtcaagtacaagggatgctgcagtgaa
caaggggataagatagttcagcttattatggaatatgtgccactgggaagccttcgagat
tatctccccaaacacaatgtgagcctggcccaaatactactgtttgcacaacagatctgt
gagggaatggcctatctccactctcagcactacatacaccgtgatctcgctgcccgcaat
gtcctcgtcgaaaatgaaaatgtggtgaaaattggagattttgggctggccaaagctgtc
ccagaaggccatgaatattacagggtcagagaggatggagacagcccggttttctggtat
gccaccgaatgtctaaaagagtgtaaattcttctatgcttctgatgtttggtcgtttggg
gtcactttctatgagctcctgactcgctgtgactcctatctcagccccccctctaaattc
atagagatgatcggggtcacccagggacagatgacggtagtgcggctgattgacctgctg
gagagaggtcagaggttaccgtgtcctagcgactgcccgctggagatctataagctgatg
aaaaactgctgggagacagaagcaaatttccgtccaacgtttaatcaccttattccaatc
ctgaaatcttttgtcaatacctactccacccaggccccatccgtgtttagcctgtgctag
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