Xenopus tropicalis (tropical clawed frog): 100495479
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Entry
100495479 CDS
T01011
Symbol
araf
Name
(RefSeq) serine/threonine-protein kinase A-Raf
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr04010
MAPK signaling pathway
xtr04012
ErbB signaling pathway
xtr04068
FoxO signaling pathway
xtr04270
Vascular smooth muscle contraction
xtr04810
Regulation of actin cytoskeleton
xtr04910
Insulin signaling pathway
xtr04914
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100495479 (araf)
04012 ErbB signaling pathway
100495479 (araf)
04068 FoxO signaling pathway
100495479 (araf)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
100495479 (araf)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100495479 (araf)
04914 Progesterone-mediated oocyte maturation
100495479 (araf)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100495479 (araf)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xtr01001
]
100495479 (araf)
Enzymes [BR:
xtr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100495479 (araf)
Protein kinases [BR:
xtr01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
100495479 (araf)
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Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
TUG-UBL1
STATB_N
Pkinase_fungal
Kdo
Motif
Other DBs
NCBI-GeneID:
100495479
NCBI-ProteinID:
XP_031746913
Xenbase:
XB-GENE-5755831
UniProt:
A0A803KBU8
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Position
8:complement(1487713..1512544)
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AA seq
644 aa
AA seq
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MKRSHTPPGALANGALHSLSRELGKGSAVMLSAAVLELPNPGTRVPAQQESPSRGASVSE
YPHAEGKSGGTVKVYLPNQQRTVVNVRPGMTVYDSLDKALKVRGLSQECCAVYRLIQGRK
ALTDWETDITPLVGEELMVEVLADVPLSMHNFVRKTHFTLAFCDFCLKFLFHGFRCQTCG
YKFHQHCSSKVPTACVDMAKLPKPLTPLSYQDFQSYYEHPTVHLPLSPQPPSPRTQHPGS
ASFSFPGEGQPLQRHRSTSTPNVHIDSTTGPVDNSIIEEALRSAAVTPVDGPPKSAQPLG
SKSPQTKSPSETTRERKTSASDEKKKVKQLGYRDSSYYWEVNSSEVIILKRIGTGSFGTV
YRGKWHGDVAVKILKVTNPTSEQIQAFKNEMQVLRKTRHVNILLFMGFMTRPQFAIITQW
CEGSSLYRHLHVIETRFDIFQLIDIARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVK
IGDFGLATVKTRWSGSQQVEQPSGSILWMAPEVIRMQESSPYSSQSDVYAYGVVLYELMA
GLLPYANINNRDQIIFMVGRGYLTPDLSKVSNNCPKAMKRLLVNCLKFKREERPLFPQIL
SSIELLQRALPKIERSASEPSLHRAVNSEDLNPFLINTLRLVPQ
NT seq
1935 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgctctcacaccccgccgggggccctcgccaacggggccctgcactccctctcc
cgcgagctgggcaaggggagcgccgtgatgctgtcggccgccgtcctggagctgcccaac
cccggcactcgggtgcccgcccagcaggaaagccccagccggggagcctcagtcagcgag
tacccccacgcggagggcaagtccgggggaaccgtcaaagtgtatcttcccaaccagcag
aggacagtggtaaacgtgcgccctggcatgacggtgtacgactctctggataaggcactg
aaagtgcgcggtctgagccaggaatgctgcgcggtgtatcggctcatacagggccgcaaa
gccctgaccgactgggagacggacatcacccccctagtgggcgaggagctgatggtggag
gtcctggccgacgtccccctgtccatgcacaatttcgtgagaaaaacccatttcaccctg
gcgttctgcgacttctgcctgaagttcctgttccacggcttccgctgccagacctgcggc
tacaagttccaccagcactgcagcagtaaggtgcccacggcctgcgtggatatggccaag
ctgcccaagcccctgacgcctctcagttatcaagatttccagtcctactatgaacatccc
actgtccacttacccctcagcccccagccccccagcccccggactcagcacccaggaagc
gcttccttttcatttcctggtgagggacagccactgcagcggcaccgctccacctccacc
cccaacgttcatattgacagcaccacgggccccgtggataactccatcattgaggaggcg
ctgaggagtgctgcagttacaccggtcgacggcccccccaaaagtgcccagccccttggg
agtaaatctcctcaaaccaagtctccgtcggagacgacacgagagagaaagacgtctgcg
tctgacgagaagaagaaagtgaaacagctgggataccgggactccagttattactgggag
gtgaattccagcgaggtgattatcctgaagcgcatcggcacgggctccttcggcaccgtg
tatcggggcaaatggcacggggacgtggccgtgaagatcctgaaggtgaccaaccccacc
tccgagcagatccaggcctttaagaacgagatgcaggttctcaggaagacccggcacgtc
aacatcctcctcttcatgggcttcatgactcgcccgcagtttgccatcatcacccagtgg
tgcgaggggagcagcctgtaccgacacctgcacgtcatcgagacgcgattcgatatcttc
cagctcattgacatcgcccggcaaactgcgcagggaatggactatctccatgccaagaac
attatccaccgggacctgaagtccaacaacatcttcctgcacgagggcctcacggtgaag
atcggggacttcggtttggccacggtgaagactcggtggagcggatcccaacaggtggag
cagccgagcggctctattctctggatggccccggaggtgatccggatgcaggagagcagc
ccctacagctcccagtcggacgtgtatgcgtatggggtggtcctgtatgaactcatggcg
gggttactgccctatgccaatatcaacaacagagaccagatcattttcatggtgggacgc
ggttacctcactccggacctcagcaaggtgtccaacaactgccccaaggccatgaagagg
ctcctcgtcaactgcctgaaattcaagagggaagagagaccccttttcccacagatcctg
tcgtccatcgagctgctgcagcgagccctgcccaagattgagcgcagcgcgtccgaaccc
tccctgcaccgcgccgtcaactccgaggacctgaaccccttcctcatcaacaccctgcga
ctggtgccccagtga
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