KEGG   Yersinia enterocolitica FORC_002: FORC2_0226
Entry
FORC2_0226        CDS       T03890                                 
Name
(GenBank) siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
yef  Yersinia enterocolitica FORC_002
Pathway
yef00860  Porphyrin metabolism
yef01100  Metabolic pathways
yef01110  Biosynthesis of secondary metabolites
yef01120  Microbial metabolism in diverse environments
yef01240  Biosynthesis of cofactors
Module
yef_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
yef_M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:yef00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    FORC2_0226
Enzymes [BR:yef01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     FORC2_0226
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     FORC2_0226
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     FORC2_0226
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Shikimate_DH
Other DBs
NCBI-ProteinID: AKF36373
LinkDB
Position
complement(288270..289688)
AA seq 472 aa
MDYFPIFCQLQNKACLLVGGGEVAERKARLLLDAGAVVTVNACEFTEQFHDWAEQGQLSL
VSGEFAPELLAEKWLVIAATDQVAVNALVYQSAHQQRVFCNVVDDPKRTSFIMPSIIDRS
PIMIAISSGGKAPVLARLLREKLEAMLPQHLGQLAQLAGHLRQRVKQHFAAMTDRRRFWE
KLLTHDRLAQSLANEDQVQVEQHVEQLFNAPLSDRGEVVLVGAGPGDAGLLTLKGLQQIQ
QADVVVYDRLVSDEVMNLVRRDAERIFVGKESGRHTVPQDQINQILLQQAQQGKRVVRLK
GGDPFIFGRGGEELETLADYDIPFSVVPGITAASGCSAYSGIPLTHRDHAQSVRLITGHA
KKDSQLDWANLAAEKQTLVFYMGLSQAAEIQQQLIRHGMPAATPVALVENGTSRHQRVVS
GELSQLALLSQQVSSPSLIIVGSVVSLREKLNWFSSAEHGKAGTKEQVEKVG
NT seq 1419 nt   +upstreamnt  +downstreamnt
atggactacttcccgattttctgccaactgcaaaacaaagcctgcctgctggtcggtggt
ggtgaagtggccgaacgtaaagctcgcttattgcttgatgcgggtgctgtcgtcaccgtc
aatgcctgtgaatttaccgagcagtttcacgattgggcggagcaagggcaactttcatta
gttagcggcgaattcgcaccggaactgttggcagaaaaatggttggtgattgcagcgact
gaccaggtggccgtcaatgcgttggtctatcaaagcgcccaccaacagcgagtgttctgc
aatgtggttgatgacccgaagcgcaccagttttattatgccatcaatcattgaccgctct
cctatcatgatagctatctcttctggcggaaaagctccagtgttagcgcgattgctgcga
gaaaaactggaagctatgctgccacagcatttgggccaattggcacagttggcaggtcac
ttacgtcagcgggtaaaacagcattttgccgcgatgactgaccgtcgccgtttctgggaa
aaactgctcacccacgaccgtctggcgcaatcactggctaatgaggatcaggtacaagtc
gagcaacacgttgagcaactgttcaatgcgccactgtctgatcgcggcgaagtagtatta
gttggagccgggccgggggatgctggtttgctgacattgaaaggtttacagcagattcag
caagctgacgtggtggtatatgaccgcctggtgtccgatgaagtgatgaatttagtgcga
cgcgacgccgagcgaatttttgtcggtaaagagtctggccgccacaccgtaccacaggat
caaatcaatcagattttgctgcaacaggcgcaacaagggaaacgcgtggtgcgtttgaaa
ggcggcgatccgtttatttttggccgtggcggcgaagagctggaaacactggcagactac
gatattccgttttctgtggtaccgggaattaccgctgcatctggctgttcagcctacagt
ggcattccactgacccatcgcgatcacgcccagagtgtgcggctgattaccggccacgcc
aaaaaagacagtcagttggattgggcaaatctggcggcagaaaaacaaactttagtgttc
tatatgggcctatcacaggccgcagagattcagcagcaactgattcgacacggtatgcca
gcggcaacccctgttgctctggtcgagaatggtacctcacggcatcagcgggtggtaagc
ggcgaactgagtcagctggcactactttctcagcaagtcagcagcccaagcctgattatc
gtcggcagtgttgtcagcttacgtgaaaaactgaattggttttccagcgcggaacatggc
aaagcagggacgaaggaacaagttgaaaaagtgggttaa

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