Yersinia enterocolitica subsp. enterocolitica 8081 (serotype 0 8): YE0600
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Entry
YE0600 CDS
T00469
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
yen
Yersinia enterocolitica subsp. enterocolitica 8081 (serotype 0:8)
Pathway
yen00260
Glycine, serine and threonine metabolism
yen00261
Monobactam biosynthesis
yen00270
Cysteine and methionine metabolism
yen00300
Lysine biosynthesis
yen01100
Metabolic pathways
yen01110
Biosynthesis of secondary metabolites
yen01120
Microbial metabolism in diverse environments
yen01230
Biosynthesis of amino acids
Module
yen_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
yen_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
yen_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
yen00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
YE0600 (thrA)
00270 Cysteine and methionine metabolism
YE0600 (thrA)
00300 Lysine biosynthesis
YE0600 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
YE0600 (thrA)
Enzymes [BR:
yen01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
YE0600 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
YE0600 (thrA)
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Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
CAL10714
UniProt:
A1JJC6
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All DBs
Position
687253..689712
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AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANAERFMRVADIIESNARQGQVATVLSAPAKITNHLVAMIDKMVAGQDI
SPNISDAERIFSELLRGLADAQPGFEYERLKALVAHEFAQLKHVLHGISLLGQCPDSINA
AIICRGEKLSIAIMEALFQAKGYKVSVINPVEKLLAQGHYLESTVDITESTRRIGSSSIP
TDHIILMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRVV
PDARLLKSMSYQEAMELSYFGASVLHPRTIAPIAQFQIPCLIKNTSNPQAPGTLIGGESS
DDGFPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRSGISVVLITQSSSEYSISF
CVPQGELIRARQALEEEFYLELKDGLLEPLDVMEHLAIISVVGDGMRTLRGISARFFSAL
ARANINIIAIAQGSSERSISVVVSNDAVTTGVRVCHQMLFNTDQVIEVFVIGVGGVGGAL
IEQIYRQQPWLKQRHIDLRVCGIANSKAMLTNVHGISLDNWRHELAEVQEPFNISRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLADGFHVVTPNKKANTSSMNYYRQMRVAAAKSC
RKFLYDTNVGAGLPVIENLQNLLNAGDELMRFSGILSGSLSFIFGKLDEGMTLSEATLQA
KALGYTEPDPRDDLSGMDVARKLLILAREAGYKLELADIEVESVLPASFDASGDVDSFLA
RLPSLDAEFTRLVANAAEQGKVLRYVGVIEEGRCIVRMDAVDGNDPLYKVKNGENALAFY
THYYQPIPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaatttggcgggacatcagtagcaaatgcagaacgctttatgcgtgtt
gccgatatcattgagagtaatgcgcgtcagggacaagtggctacggtattatccgctccc
gctaaaattaccaaccatctggtggcgatgatcgacaaaatggtggctgggcaagatatc
tcgccgaacatcagtgatgcggaacggattttttccgagctattgcgtggcttggctgat
gcgcaaccgggctttgaatatgaacgtttaaaagcgctggtggcccatgagtttgcgcaa
ctcaaacacgtcctgcacggtatttcgttgctcggtcaatgcccggatagtattaatgcc
gccatcatctgtcgcggcgagaaattgtccattgccattatggaagcattgttccaggcg
aaaggttataaagtcagcgtgattaatccggtcgagaaattgttggcgcagggccattat
ctcgaatccaccgtcgatatcactgaatctacccgccgcatcggctccagcagcattcct
actgaccatatcatcctgatggctggtttcactgccggtaatgacaaaggggagttggtg
gtactggggcgcaatggatcagactattcagctgcggtgttggccgcgtgtttacgcgct
gattgttgtgagatctggactgacgtggacggggtttatacctgtgacccacgcgttgta
cctgatgctcgattattgaaatcgatgtcatatcaggaagcgatggagctgtcttatttt
ggcgcttcggttctccacccccgcactatcgctcctatcgcccagttccaaattccttgc
ctgattaaaaatacctctaacccacaagcccccggtaccttgattggtggtgaaagtagt
gatgatggtttcccagtgaaaggcatcaccaatctgaataacatggcgatgattaacgta
tctggcccaggtatgaaaggcatggtcggtatggctgcccgcgtctttgcggtgatgtcg
cgcagcggtatctcagtagtacttattactcaatcttcttctgagtacagcatcagcttc
tgtgtgccgcaaggtgagttaatccgtgctcgccaagcattggaagaagagttctatctg
gagctgaaagatggtctgttagagccattggatgtgatggaacatctggcgattatctca
gtggttggcgatggtatgcgtactttacgtggcatctcggctcgcttcttctcagcactg
gcccgtgccaacatcaatatcattgcgattgcgcaaggttcgtccgagcgttccatctcc
gtggtggttagcaatgatgccgtcaccaccggtgtgcgagtttgtcaccagatgttgttc
aataccgatcaagttattgaagtatttgtgataggcgtaggtggtgtcggcggggcatta
atcgagcaaatctatcgtcaacaaccttggttgaaacagcgccatatcgatttacgcgtt
tgcggcatcgccaattccaaagccatgttaaccaatgtgcacggtatttcgctggataac
tggcgtcatgaactggccgaagtgcaagagccttttaacataagtcgcttaattcgtctg
gtgaaagagtatcacttgctcaatccggtaattgtcgactgtacatccagtcaggctgtt
gcggatcaatatgcagattttctggcagatggcttccatgttgtgacaccaaacaagaaa
gccaatacctcatcgatgaattactaccgtcagatgcgcgtggcggcagcgaagtcatgc
cgtaaattcttgtatgacaccaacgtcggtgcgggcctgccggttatcgaaaacttacag
aatttgctcaatgcgggcgatgaactgatgcgtttttctggcattctgtcaggctcactc
tctttcatcttcggtaagcttgatgaagggatgaccttgtcagaggccacattgcaggcg
aaggcgctgggttatactgagccagatccacgcgatgatctttccggcatggatgtcgcc
cggaaattgttgatcctggcccgtgaagcagggtacaaacttgaattggctgatatcgaa
gttgagtctgttctaccagcaagtttcgatgcaagcggtgatgtagacagcttcctcgct
cgcctgccatcactggatgccgagtttacccgtctggtggcaaatgccgcagaacagggc
aaagtgctgcgttatgtcggggtgattgaagaggggcgttgtatcgttcggatggatgcg
gtcgatggtaacgatccgctgtataaagtaaaaaatggtgagaatgcgttggccttctat
acccactattatcagccgatcccgttggtgcttcgcgggtatggtgcgggtaatgatgtg
actgctgctggggtgttcgctgatcttttacgcacattatcatggaagttgggagtttaa
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