Yersinia frederiksenii: AW19_3942
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Entry
AW19_3942 CDS
T03606
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase 1
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
yfr
Yersinia frederiksenii
Pathway
yfr00260
Glycine, serine and threonine metabolism
yfr00261
Monobactam biosynthesis
yfr00270
Cysteine and methionine metabolism
yfr00300
Lysine biosynthesis
yfr01100
Metabolic pathways
yfr01110
Biosynthesis of secondary metabolites
yfr01120
Microbial metabolism in diverse environments
yfr01230
Biosynthesis of amino acids
Module
yfr_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
yfr_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
yfr_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
yfr00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
AW19_3942 (thrA)
00270 Cysteine and methionine metabolism
AW19_3942 (thrA)
00300 Lysine biosynthesis
AW19_3942 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
AW19_3942 (thrA)
Enzymes [BR:
yfr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
AW19_3942 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
AW19_3942 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AJI88186
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All DBs
Position
4265984..4268443
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AA seq
819 aa
AA seq
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MRVLKFGGTSVANAERFMRVADIIESNARQGQVATVLSAPAKITNHLVAMIDKMVAGQDI
SPNISDAERIFSELLRGLADAQPGFDYERLKALVAHEFAQLKHVLHGISLLGQCPDSINA
AIICRGEKLSIAIMEALFQAKGYQVSVINPVEKLLAQGHYLESTVDITESTHRIGSSKIP
TDHIILMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRVV
PDARLLKSMSYQEAMELSYFGASVLHPRTIAPIAQFQIPCLIKNTSNPQAPGTLIGGESS
DDGFPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRSGISVVLITQSSSEYSISF
CVPQSELIRARKALEEEFYLELKDGLLEPLDVMEHLAVISVVGDGMRTLRGISARFFSAL
ARANINIIAIAQGSSERSISVVVSNDSATTGVRVCHQMLFNTDQVIEVFVIGVGGVGGAL
IEQIYRQQPWLKQRHIDLRVCGIANSKAMLTNVHGIALDNWRHELAEVKEPFNLSRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLADGFHVVTPNKKANTSSMNYYRQMRAAAAKSC
RKFLYDTNVGAGLPVIENLQNLLNAGDELMRFSGILSGSLSFIFGKLDEGMTLSEATLQA
KALGYTEPDPRDDLSGMDVARKLLILAREAGYKLELADIEVESVLPANFDASGDVDSFLA
RLPSLDAEFSRLVANAAEQGKVLRYVGVIEEGRCIVRMDAVDGNDPLYKVKNGENALAFY
THYYQPIPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaatttggcgggacatcagtagcaaatgcagaacgctttatgcgggtt
gccgatatcatcgaaagtaatgcgcggcagggacaagtggcgacggtattatccgctccc
gcgaaaattaccaaccatctggtcgcgatgatcgacaaaatggtggccgggcaagatatc
tcgccgaacatcagcgatgctgagcgaattttttccgagttgctgcggggattggctgat
gctcaaccgggctttgactatgagcgtttaaaagcgctggtggcccatgagtttgcgcaa
ctcaaacacgtcctgcatggtatctcgttgcttggccaatgccctgatagcatcaatgcc
gccattatctgccgtggcgaaaaactctctatcgctatcatggaagcattattccaagcc
aaaggttatcaggttagcgtaattaatccggtcgagaaattgctggcacagggccattat
ctcgaatctacggttgatatcactgaatctacccaccgcatcggctctagcaagatccca
actgaccatatcatcctgatggccggtttcactgccggtaatgacaaaggggagttggtg
gtgctggggcgcaatggttccgactattctgctgctgtgttggctgcttgtttacgcgct
gattgttgtgaaatctggactgatgttgatggggtctatacttgcgacccacgggtggta
cctgatgcccgattattgaaatcgatgtcatatcaggaggcgatggagttgtcctatttt
ggcgcttcggttctccatccccgcactatcgcccctattgctcagttccaaattccttgc
ttgattaaaaatacctctaacccgcaagcccccggcaccctcattggtggtgaaagcagt
gatgacggcttcccggttaaaggcatcaccaacctgaataatatggcgatgattaacgtg
tctggccctggaatgaaaggcatggtcggtatggcggcccgcgtctttgccgtgatgtca
cgcagcggtatttcagtggtgcttatcacccaatcttcttctgagtacagcatcagtttt
tgcgtgccacaaagcgagttaatccgcgcccgcaaagcattggaagaagagttttatctg
gaattaaaagacggcctcttagagccattggatgttatggagcatctggcggttatctcg
gtcgtcggtgatggcatgcgcaccctgcgcggtatttcagctcgctttttctcggcgttg
gctcgcgctaatattaatatcatcgcgattgcgcaaggctcgtccgagcgctctatctct
gtggtggtcagcaatgattccgccactaccggggtgcgtgtttgccaccaaatgttgttc
aataccgatcaggtgattgaagtgtttgtcattggtgtcggcggggtcggcggggcatta
atcgaacaaatctatcgccagcagccatggctgaaacagcgtcatatagatttgcgcgtg
tgcggcattgccaactccaaagccatgttgaccaatgtgcacggcattgcgctggataac
tggcgtcacgagctggccgaagtgaaagagccgtttaatctcagccgcttgattcgcttg
gtaaaagagtatcatttgctcaatccggtgattgtcgattgtacctctagccaagccgtg
gcggatcaatatgcagatttcctggcggacggtttccatgtcgtcacgccaaataagaaa
gccaatacctcatcaatgaattactaccgtcagatgcgcgcagcagcagcaaaatcatgc
cgtaaattcttgtatgacaccaacgtcggcgcgggcctgcctgttatcgaaaacttacag
aatttgcttaatgctggtgacgaactgatgcgtttttctggcattctgtcagggtcgctg
tcctttatcttcggcaagttggacgaggggatgacattatccgaggccacattgcaggcc
aaagctctgggttataccgagccagacccgcgcgatgacctttctgggatggatgtcgcc
cgtaaattgttgattttggcccgcgaagcagggtacaaactggagttggcagatattgaa
gttgaatcagttctgccagccaactttgatgccagcggcgatgtagatagcttcctcgct
cgcttgccgtcactggatgccgagtttagtcgcctggtggcaaatgccgccgaacagggc
aaagtgctgcgttatgtcggggtgattgaagaggggcgctgtatcgtccggatggatgcc
gtagatggtaacgatccgctgtataaagttaaaaatggcgagaatgcgttggctttctat
acccactattatcagccaattccgttggtgctgcgcgggtatggcgcggggaatgacgtg
acagcggccggggtatttgctgatcttttacgcacattatcatggaagttgggagtttaa
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