Yersinia pestis Harbin 35 (biovar Medievalis): YPC_1522
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Entry
YPC_1522 CDS
T01874
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
yph
Yersinia pestis Harbin 35 (biovar Medievalis)
Pathway
yph00790
Folate biosynthesis
yph01100
Metabolic pathways
yph01240
Biosynthesis of cofactors
Module
yph_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
yph00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
YPC_1522 (folC)
Enzymes [BR:
yph01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
YPC_1522 (folC)
6.3.2.17 tetrahydrofolate synthase
YPC_1522 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ADV98140
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Position
1492138..1493442
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AA seq
434 aa
AA seq
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MNNHQTPQATSPLAAWLCYLEHLHSQPIELGLERVKQVAERLDLLKPAPKIFTVAGTNGK
GTTCCTLEAILLAAGLRVGVYSSPHLLRYTERVRIQGQELSEAEHSHSFAQIEAGRGDIS
LTYFEFGTLSALQLFKQAKLDVVILEVGLGGRLDATNIVDSDVAAITSIALDHTDWLGYD
RESIGREKAGVFRGGKPAVVGEPDMPQSIADVAAELGAQLYRRDVAWKFSQQEPFDQQEP
VDQQINGWHWQCGERQLTGLPVPNVPLANAATALAVLHYSELPLSDEAIRQGLQAASLPG
RFQVVSEQPLLILDVAHNPHAARYLVNRLAQVINPVNASKQGKVRAVVGMLSDKDIAGTL
ACLSERVDEWYCAPLEGPRGASAGQLAEHLVSARQFSDVETAWRQAMQDADTQDVVIVCG
SFHTVAHVMAALHL
NT seq
1305 nt
NT seq
+upstream
nt +downstream
nt
atgaacaatcatcaaactccccaagccacgtcgcctttggccgcgtggctttgctatctt
gagcatttgcattctcagcccattgagttgggtctggaacgtgttaaacaggttgctgag
cgtctggatctgcttaaacctgcccccaaaatttttaccgttgccggtaccaacggcaaa
ggtaccacttgttgtacattggaagccattttattggcggccggtctgcgagtcggggtc
tacagctccccccaccttttacgctataccgagcgggttcgaattcaggggcaagagcta
tctgaggcagaacacagccactcttttgcccagatcgaagccgggcgaggtgatatctca
ctgacctactttgaatttggcaccttatcagcgttgcaactatttaagcaggctaaactt
gatgtggtgatcctggaagtcgggttgggtgggcggttagatgcgaccaatattgttgac
tctgatgtcgccgccatcaccagtatcgcgttagatcatactgattggctgggttatgac
cgtgaaagcattggccgcgagaaggcgggtgtcttccgtggcggtaaacctgcggtcgtg
ggtgaaccagatatgccccagtctattgccgatgtggcggctgagttaggcgcacagctc
tatcgtcgggatgttgcctggaaattcagccagcaagaaccgtttgatcaacaagaaccc
gttgatcaacaaataaacggctggcactggcagtgcggtgagcgccaattaaccggctta
ccggtgccgaacgtgccgctggcgaatgcggctacggcgctggctgtactgcattattct
gagttgccattgagtgacgaggcgattcggcaggggttacaggccgccagtttaccaggg
cgttttcaggtcgtcagtgagcaaccgttgctgattctggatgtcgcccataatccgcat
gcggcccgttatctggtcaatcggttggcccaagttattaacccggttaatgcgtcgaaa
caaggcaaagtgcgggcagtcgtcgggatgctatcggataaagatattgcgggtacgctg
gcatgtttatctgagcgagttgatgagtggtattgcgctccgcttgaagggccacgagga
gccagtgctgggcaattggccgaacatctggtgagcgcacgtcagtttagtgatgtagaa
actgcctggcgccaggctatgcaagatgcagatacacaggatgtggtcattgtctgtggc
tctttccatactgttgcccatgttatggcagcattgcatttgtga
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