Yersinia pestis KIM10+ (biovar Mediaevalis): y1178
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Entry
y1178 CDS
T00092
Symbol
mrdA
Name
(GenBank) peptidoglycan synthetase, penicillin-binding protein 2
KO
K05515
penicillin-binding protein 2 [EC:
3.4.16.4
]
Organism
ypk
Yersinia pestis KIM10+ (biovar Mediaevalis)
Pathway
ypk00550
Peptidoglycan biosynthesis
ypk01100
Metabolic pathways
ypk01501
beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:
ypk00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
y1178 (mrdA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
y1178 (mrdA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
ypk01011
]
y1178 (mrdA)
Enzymes [BR:
ypk01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
y1178 (mrdA)
Peptidoglycan biosynthesis and degradation proteins [BR:
ypk01011
]
Peptidoglycan biosynthesis and degradation
DD-Transpeptidase (Class B PBP)
y1178 (mrdA)
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Gene cluster
GFIT
Motif
Pfam:
Transpeptidase
PBP_dimer
Motif
Other DBs
NCBI-ProteinID:
AAM84755
UniProt:
A0AAX2I398
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All DBs
Position
complement(1321732..1323627)
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AA seq
631 aa
AA seq
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MKKEPNPFRDYSAESALFVRRAVVAFLGILLLSGVLVANLYNLQIIRFDDYSTRSNDNRI
KLVPIAPSRGMIFDRNGTPLALNRTIYQLELMPEKIENLSATLNALRPIVDLTDDDIANF
EKERKRSRRFTSIAVKTPLTEVQVARFAVNQFRFPGIEVKGYQRRFYPYGSALTHVIGYV
SKINDKDVERLDKEGILPNYAATHDIGKLGIERYYESTLHGKTGYEEVEVNNRGRVIRQL
HEQPPQAGKDIYLTLDLSLQIYIEKLLSGSRAAVVVTDPRTGGILALVSNPSYDPNLFVD
GISNKDYQGLLNDTNRPLINRATQGVYPPASTVKPYIAVSALSAGVITKNTSLFDPGWWQ
LPGSEKRYRDWKKWGHGRLNVTKALEESADTFFYQVAYDMGIDRLSSWMSKFGYGEYTGI
DLSEERAGLMPTREWKQKRHKKPWYQGDTIPVGIGQGYWTATPIQMAKSLMTLINDGTVK
TPHLLQSTRIDGVLVPYKQEDSTQIGSINSGYWEIAKDGMYGVANRPNGTGRKFFEGTPY
KAAAKSGTAQVYSYETYNASKVAEHLRDHKLMVAFAPYENPTVSVAIILENGGAGPAVGT
ITRQILDHILLGDNNTELPDAVPLPPGVEAD
NT seq
1896 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaaagaacctaacccttttcgcgactattcggctgaatcagccctgtttgtccgc
cgcgccgtagtggcttttctgggtatcctgctactgagcggggtactggttgctaacctc
tataatttgcaaataatccgtttcgacgattacagcacccgctccaacgacaaccgcatc
aaactggttcctatcgcccctagccgtggcatgatatttgacagaaatggcacaccactg
gcattaaaccgcaccatctatcaattagagttgatgccggaaaagatcgaaaacttgtca
gccaccctcaatgcgctgcgcccaatagtggatctgactgacgacgatatcgctaacttt
gaaaaagagcgcaaacgctcacgtcgctttacctctattgccgttaaaacaccgttgacc
gaggtgcaagtcgcccgttttgcagtgaatcaattccgcttccccggaattgaagtcaaa
ggctatcaacgtcgcttctacccgtatggctccgccctgacccacgtgattggctatgtc
tctaaaattaacgataaagatgtcgaacggttggataaagaaggcattctccccaattat
gctgcgacccacgatatcggtaagttgggtattgaacgctattatgaatccaccttacat
ggcaaaactggttatgaagaagttgaagtcaataaccgaggccgggtaatccgccaatta
catgagcaaccgccacaagcaggtaaagatatttatctgactctcgatctgagtctacaa
atctatatcgagaagttactcagtggcagccgtgctgcggtcgtcgtcacagacccacgc
accggcgggatcctggccttggtatcaaacccaagctatgacccgaacctgtttgtcgac
ggcatctccaacaaagattatcaagggttgcttaacgatacgaaccgccccttaatcaat
cgggcaacccaaggcgtttatccaccggcatcaaccgtgaaaccgtacatcgcagtgtca
gcactgagtgccggggttatcaccaaaaacaccagcctgttcgatcctggttggtggcaa
ctgcccggttcggaaaagcgctaccgtgactggaaaaaatggggccatggccgcctgaac
gtcaccaaagcactggaagaatcggcagataccttcttctaccaagtcgcctatgatatg
ggcattgatcgcttatcatcttggatgagcaaattcgggtacggtgaatatactggcatt
gatttatccgaagagcgtgcgggtttaatgccaacacgcgagtggaagcaaaagcgccat
aaaaagccttggtatcagggtgataccattccggtaggtattggccagggttattggact
gcgacgccaatccagatggctaaatccttaatgaccctgattaatgatggcacagttaag
acacctcacctgttgcaaagcacccggattgatggcgtattagtgccctataagcaggaa
gacagtacgcagattgggagtatcaattctggctattgggaaattgctaaagacggcatg
tatggcgtagcgaaccgcccgaacggtactggccgcaagttttttgaaggtacaccttat
aaggcagcggcgaaatcgggtaccgcacaggtttacagttatgaaacctataatgccagt
aaagtggcagaacacctgcgcgaccataagttaatggttgcgtttgctccctatgagaac
cctacggtatccgttgcaataatcttggaaaatggaggcgcggggcctgcggtagggacc
attacccgtcagatcctcgaccatatcttgttgggcgataataatactgaattaccggat
gcggttcctctgcctcctggcgttgaagcagattag
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