Yersinia pestis KIM10+ (biovar Mediaevalis): y1309
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Entry
y1309 CDS
T00092
Symbol
purL
Name
(GenBank) phosphoribosylformyl-glycineamide synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ypk
Yersinia pestis KIM10+ (biovar Mediaevalis)
Pathway
ypk00230
Purine metabolism
ypk01100
Metabolic pathways
ypk01110
Biosynthesis of secondary metabolites
Module
ypk_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ypk00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
y1309 (purL)
Enzymes [BR:
ypk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
y1309 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
AAM84883
UniProt:
Q8ZCQ2
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Position
1451746..1455636
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AA seq
1296 aa
AA seq
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MEILRGSPALSAFRITKLLSRCQDAHLPVSDIYAEYVHFADVSAPLSADEHARLQRLLQY
GPSLPEHPPAGRLLLVTPRPGTISPWSSKATDIAHNCGLSQILRLERGLAFSIQGPDLNE
SQWKQLAALLHDRMMEAVFTDLQQAEQLFSHHQPAPVQRVDILGQGRSALEQANIKLGLA
LAQDEIDYLLTAFTGLGRNPTDIELYMFAQANSEHCRHKIFNADWVIDGVVQPKTLFKMI
KNTFEHTPDYVLSAYKDNAAVMEGSQVGRFYATAEKGIYDYHQEEAHILMKVETHNHPTA
ISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEENFGKPDRIVT
ALDIMTEGPLGGAAFNNEFGRPALLGYFRTYEERVNSHNGIELRGYHKPIMLAGGLGNIR
ADHVQKGEITVGAKLVVLGGPSMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRC
QEVIDRCWQLGEYNPILFIHDVGAGGLSNAMPELVNDGGRGGRFELRDILNDEPGMSPLE
VWCNESQERYVLAVAPAQMALFDEICRRERAPYAVIGEATEEKHLLLNDRHFGNQPIDMP
LDVLLGKTPKMLRDVTRLQAKGDALQRADISLAEAVKRIMHLPAVAEKTFLITIGDRTVT
GMVTRDQMVGPWQIPVADCAVTSASLDSYYGEAMSLGERAPVALLDFAASARLAVGEALT
NIAATQIGELKRIKLSANWMSAAGHPGEDAGLYDAVRAVGEELCPALEITIPVGKDSMSM
KTRWQEGHEQREMTSPLSLVITAFARIEDVRRTVTPQLRTDKGDNALLLIDLGAGHNALG
ATALTQVYRQLGDKPADVRNVQQLAGFFNAMQRLVADQHLLAYHDRSDGGLLVTLAEMAF
AGHCGVTVDIQSLGNDALAALFNEELGAVIQVRAEQRADVEKLLADHGLANCVHYLGRAV
AGDTFDIRSGTDVVYSEKRSTLRLWWAETSWQMQRLRDNPDCADQEHQAKQDESDPGLNV
KLTFDPAEDIAAPFILKQARPKVAVLREQGVNSHVEMAAAFHRAGFDAVDVHMSDLLAGR
TDLQSFQTLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFEAFFHRPTTLALGVCNGCQ
MMSNLRELIPGAEHWPRFVRNLSDSFEARFSLVEVASSPSLFMQDMVGSRMPIAVSHGEG
QVEVRDAAHLAALEQSHLVALRFVNNHGVVTEQYPANPNGSANGITAVTSVSGRATVMMP
HPERVFRTVSNSWHPEEWGEDSPWMRMFRNARKQLG
NT seq
3891 nt
NT seq
+upstream
nt +downstream
nt
atggaaatactgcgtggttcacccgctttgtcggcttttcgtatcaccaaactgttgtcc
cgttgccaggatgctcacctgccggtgagtgatatctacgccgaatatgttcactttgct
gatgtcagcgccccactgagtgctgatgaacacgccagactccagcggctgcttcaatat
ggcccatctcttcccgagcatccccccgcagggcgtttactgctggtcaccccaaggccg
ggtactatttctccatggtcttctaaagccaccgatatcgcacataactgtggattatca
caaattttacgtttagaacgtggtttggctttctctatccaaggcccggatttaaacgag
agtcagtggaaacaattagcggcgttattacatgaccgcatgatggaagctgtcttcacc
gatttacagcaagcagagcagctattctctcatcaccaaccagcaccagtacaacgggtc
gatattctggggcagggccgcagtgcattggagcaggccaatattaaattgggtctggca
ctggcgcaggatgagattgactacttactgaccgcttttaccggtttggggcgcaaccca
acggatattgagctgtatatgtttgcgcaggcaaactcagagcattgccgccataaaatc
tttaatgcggattgggtcattgatggtgttgttcagccgaagaccctgttcaagatgatc
aaaaacaccttcgaacacacccctgattatgtgctgtctgcatataaagacaacgctgcg
gtgatggaaggctctcaggtcgggcgtttctatgccacggcggagaaagggatttatgac
taccatcaggaagaagcccatatcctgatgaaggttgaaactcataaccacccgacagcg
atttcaccgtggcctggggcagcaaccggttcagggggtgaaatccgcgatgaaggtgca
accgggcgtggtgccaagcctaaagcggggctggtagggttctccgtttcgaacctgcgc
attccaggttttgagcagccgtgggaagagaacttcggtaagcctgatcgtatcgtgact
gcgctagatatcatgactgaaggcccattaggcggtgccgcgtttaacaatgagtttggt
cgcccggcgttgttgggttacttccgcacctatgaagagcgggttaacagccataacggt
attgaattacggggttaccataagcctattatgttggcgggtgggttgggtaatattcgt
gccgatcatgtgcaaaaaggtgaaatcaccgtgggggccaaattggtcgtactcggtggc
ccatcgatgaatatcggtttaggggggggcgcggcttcctctatggcatccgggcagtcg
gatgcggatctggattttgcatcggtacaacgggataacccagaaatggagcgccgttgt
caggaagttatcgatcgctgctggcagttgggcgagtataaccccattctgtttatccat
gatgttggcgccggtggcctctctaatgccatgcctgaactggtcaacgatggtggccgt
ggtggccgctttgaattgcgggatatcctcaacgacgaaccgggtatgagcccgctggaa
gtgtggtgtaacgagtctcaggagcgttatgtactggcagtcgcacccgcacagatggcc
ctgtttgacgaaatttgccgccgtgaacgcgcgccgtatgctgttattggtgaagcgaca
gaagaaaaacatctgctcctgaatgatcgccatttcggcaatcaacccattgatatgccg
ctggatgtgctattaggcaaaacgccgaagatgctgcgtgatgttacccgcctacaggct
aagggtgacgcgctgcaacgggctgatattagccttgccgaggcggtaaaacgcattatg
catttaccggcggtagcggaaaaaaccttcctgatcaccatcggcgaccgcacggtaacc
ggtatggtcacccgtgatcagatggttggcccttggcagatccccgtggctgattgcgcg
gtaaccagtgccagccttgatagctattatggcgaagccatgtcgctgggcgagcgcgct
ccggtggcattgctggactttgccgcctctgcccgtctggcggttggtgaagccttgacg
aacatcgcagcaacccaaattggtgaattaaagcgtatcaagttatctgctaactggatg
tctgctgctggtcacccaggggaagatgctggtttgtatgacgcggtacgtgcggtaggt
gaagagctgtgcccagccctggaaatcacgattcctgtgggcaaagattcgatgtcgatg
aaaacccgctggcaggaaggtcacgagcagcgcgaaatgacctcaccgctgtcactggtg
atcaccgcttttgctcgcatagaagatgttcgccgcaccgtgacaccacaattgcgtaca
gataaaggtgataacgcgctgttgttgatcgatttgggcgcaggtcacaatgcgctcggt
gcgactgcgctgacgcaagtttaccgccagttaggtgataaaccagcggatgtccgtaac
gtgcagcaactggctggcttcttcaacgccatgcagcgtttagtagccgatcaacatttg
ttggcgtaccacgaccgctccgatggcggcttgttggtcacgctggccgaaatggccttt
gcagggcattgtggcgtaacggttgatattcagtctttgggtaacgatgctctggctgca
ctgttcaacgaggaactgggtgcagtgattcaagtccgtgctgagcagcgtgccgacgtg
gagaaattgctggctgaccacggtctggcaaattgtgttcactatctggggcgtgcggtt
gcgggcgatacctttgatattcgcagtggtactgacgtggtgtacagcgagaaacgcagc
actctgcgcttgtggtgggcagaaacgagctggcaaatgcagcgtctgcgtgataatccg
gattgtgctgatcaagaacatcaggctaaacaggatgaaagtgatcccggcctgaatgtg
aaactgacgttcgaccccgctgaagatatcgcggcaccattcatcctcaaacaggcgcgg
ccaaaagttgctgtgctgcgggagcagggcgttaactctcacgttgagatggccgcggct
ttccaccgtgccgggtttgatgcggtcgacgttcatatgagtgacctgttggcgggccgc
actgatttacaatccttccaaaccttagttgcttgtggcgggttctcttacggtgacgtc
ttgggggccggtgaaggttgggcaaaatccattctgttcaatgatcgtgttcgtgatgaa
ttcgaggctttcttccatcgcccaacgacattggcgcttggggtttgtaacggctgtcag
atgatgtctaatctgcgtgaattaatcccaggtgcggagcattggccacggtttgtacgc
aacttatcagatagctttgaagcacgtttcagcctggttgaagtggcaagcagcccatca
ctgtttatgcaggacatggtcggctcacgtatgccaattgctgtttcacatggtgaaggg
caggtggaagtccgtgatgcggcacatttggctgctctggaacagagtcatctggtggcg
ttacgctttgtgaataaccacggggttgtcactgagcaatatccggctaacccaaatggt
tccgcgaatggtattacggcggtgaccagtgttagtgggcgggccacggtaatgatgcca
caccctgagcgggtgttccgtacggtcagtaattcgtggcacccagaagagtggggcgag
gatagcccatggatgcgtatgttccgtaatgcgcgtaagcaattaggttaa
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