Yersinia pestis KIM10+ (biovar Mediaevalis): y3645
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Entry
y3645 CDS
T00092
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ypk
Yersinia pestis KIM10+ (biovar Mediaevalis)
Pathway
ypk00290
Valine, leucine and isoleucine biosynthesis
ypk00620
Pyruvate metabolism
ypk01100
Metabolic pathways
ypk01110
Biosynthesis of secondary metabolites
ypk01210
2-Oxocarboxylic acid metabolism
ypk01230
Biosynthesis of amino acids
Module
ypk_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ypk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
y3645 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
y3645 (leuA)
Enzymes [BR:
ypk01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
y3645 (leuA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
AAM87193
UniProt:
Q8ZIG8
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All DBs
Position
4042224..4043786
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AA seq
520 aa
AA seq
DB search
MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDIMEVGFPVSSPGDFESVRT
IAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHIESKLKRSFDDVLA
MAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAITAGATTINIPDTVGYTPPYQF
GGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQVEGTINGLGERAGNCS
LEEVIMAIKVRHEMLGVHTNINHQEIYRTSQLVSKICNMPIPGNKAIVGSNAFAHSSGIH
QDGVLKNRENYEIMTPESIGLKEVQLNLTSRSGRAAVKHRMEEMGYQDKDYNLDSLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEYYRLDYFSVQSGSSVMATASVKLVCGEEIKS
EAATGNGPVDAVYQAINRITDYPIELVKYQLSAKGQGKDALGQVDIVVDHKGRRFHGVGL
ATDIVESSAKALVHVLNNIWRAHQVEKEKQRLQQNNQEMV
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgagccaacaagtcattatttttgatacaacattgcgcgacggtgaacaagcattgcaa
gccagtctgagtgtgaaagagaagctgcaaatcgcgctggcattggaaagaatgggggtc
gatatcatggaggtgggtttccctgtctcctcccctggtgattttgaatcggttcgtact
atcgctcagcaagtgaaaaatagccgggtttgcgccttggcacgttgtgtggataaagat
attgatgttgcggcagaggcattgcgaattgcagaagctttccgtattcatgtgtttttg
gccacctcaaccttgcatatcgaatccaagttaaagcgttcgtttgacgatgtgctggcg
atggcggtccactccgtgaaacgtgctcgtaactataccgatgacgtcgagttttcttgt
gaagatgctggccgtactccaattgataacttatgccgtgtcgtcgaggccgcgattacc
gccggtgccaccacaatcaatatcccggataccgtcggttacacccccccttatcaattt
ggtggcatcatcactgacttgtatgaacgtgttcccaatattgataaagccattatctct
gttcattgccatgatgacttgggcatgtccgttgccaactccattactgcagtacaagcc
ggggcgcgtcaggtcgaagggaccatcaacggcttaggtgagcgtgcaggtaactgttca
ttggaagaggtgatcatggccattaaagtgcgccatgaaatgttgggcgtgcacaccaat
atcaatcatcaggaaatttaccgtaccagccagttggtcagtaaaatttgcaatatgcct
attcccggcaataaagccattgtcggcagtaatgccttcgctcactcctccggtattcat
caggatggtgtcctgaaaaatcgcgaaaactacgaaatcatgaccccggaatccatcggt
ctgaaagaagtccaattgaacctgacatcccgttcaggtcgtgcggcagtgaagcaccgg
atggaagagatgggttatcaggataaagattacaatttagattctttgtacgatgccttc
ttgaaattagccgataaaaaaggccaggtctttgactacgatttggaagcattggccttt
attaataagcagcaggaagagcctgaatattatcgtttggactatttcagcgtccagtcg
ggttccagtgtcatggcaactgcctcagtaaaattggtctgtggtgaagaaataaaatca
gaagcggccaccggtaacggcccggttgatgcggtgtatcaggccatcaatcgcattacc
gactacccaattgaactggtgaagtatcaactgtcggccaaaggtcagggtaaagatgca
ttgggtcaggttgatatcgtggttgaccacaaggggcgtcgcttccatggcgtaggtttg
gcaactgacattgttgagtcatccgctaaggcgttggttcacgtattaaataacatctgg
cgcgcccatcaggtcgaaaaagagaagcagcgtctgcaacaaaataatcaggaaatggtg
tga
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