Yersinia pestis 91001 (biovar Microtus): YP_3723
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Entry
YP_3723 CDS
T00165
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
ypm
Yersinia pestis 91001 (biovar Microtus)
Pathway
ypm00260
Glycine, serine and threonine metabolism
ypm00261
Monobactam biosynthesis
ypm00270
Cysteine and methionine metabolism
ypm00300
Lysine biosynthesis
ypm01100
Metabolic pathways
ypm01110
Biosynthesis of secondary metabolites
ypm01120
Microbial metabolism in diverse environments
ypm01230
Biosynthesis of amino acids
Module
ypm_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
ypm_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
ypm_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
ypm00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
YP_3723 (thrA)
00270 Cysteine and methionine metabolism
YP_3723 (thrA)
00300 Lysine biosynthesis
YP_3723 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
YP_3723 (thrA)
Enzymes [BR:
ypm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
YP_3723 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
YP_3723 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AAS63871
UniProt:
A0A0H2W986
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All DBs
Position
complement(4239184..4241637)
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AA seq
817 aa
AA seq
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MLKFGGTSVANAERFMRVADIIESNARQGQVATVLSAPAKITNHLVAMIDKMVAGQDISP
NISDAERIFAELLRGLADTQPGFDYDRLKALVGHEFAQLKHLLHGISLLGQCPDSINASI
ICRGEKLSIAIMEALFQAKGYHVTVINPVEKLLAQGHYLESTVDITESTRRIGASGIPSD
HIILMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTVPD
ARLLKSMSYQEAMELSYFGAKVLHPRTIAPIARFQIPCLIKNTSNPQAPGTLIGGESIDE
DSPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRSGISVVLITQSSSEYSISFCV
PQGELLRARRALEDEFYLELKDGVLDPLDVMEHLAIISVVGDGMRTLRGISARFFSALAR
ANINIIAIAQGSSERSISVVVNNDAVTTGVRVCHQMLFNTDQVIEVFVIGVGGVGGALIE
QIYRQQPWLKQRHIDLRVCGIANSKAMLTNVHGIALDNWRQELAEVQEPFNLSRLIRLVK
EYHLLNPVIVDCTSSQAVADQYADFLTDGFHVVTPNKKANTSSMNYYRQMRAAATKSCRK
FLYDTNVGAGLPVIENLQNLLNAGDELMRFTGILSGSLSFIFGKLDEGMSLSEATRQAKA
LGYTEPDPRDDLSGMDVARKLLILAREAGYKLELADIEVESVLPASFDASGDVDTFLARL
PSLDAEFTRLVANAAEQGKVLRYVGVIEDGRCKVRMEAVDGNDPLYKVKNGENALAFYTR
YYQPIPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2454 nt
NT seq
+upstream
nt +downstream
nt
gtgctgaaatttggcgggacatcagtggcaaatgccgagcgctttatgcgtgttgccgat
atcatcgaaagtaatgcgcgtcagggacaagtggctacggtgttatccgctcccgcgaag
ataacgaaccatctcgttgccatgatcgataaaatggtcgcagggcaagatatctccccg
aacatcagcgatgctgagcggatttttgctgagttattgcgtggattagctgatactcag
ccaggctttgattatgatcgcctaaaagccttggtcggccatgagtttgcgcaactcaaa
cacctgctacacggtatttcgttgttggggcagtgcccagacagcattaatgcctcaatt
atctgccgtggcgaaaaactctccatcgccattatggaggcgttatttcaggctaagggt
tatcacgttacggtgattaatccagtcgaaaaattgttggcgcagggccattatctcgaa
tccactgttgatatcacggagtctacccgccgtatcggtgccagcggtattccatctgat
cacatcatcctgatggctggttttactgcgggtaatgataaaggtgaattggtggtgttg
gggcgtaatggctctgattattccgctgccgtgctggctgcttgcttacgggcagattgt
tgtgagatttggaccgatgtcgacggggtctatacttgtgacccgcgtaccgttccagat
gccagattactgaaatcgatgtcataccaagaggcaatggagctttcctattttggtgct
aaagttcttcaccctcgcactatcgctcctattgcccgcttccaaattccttgtctgata
aaaaacacctctaacccgcaagcccccggtaccttgattggtggtgaaagcattgatgag
gattctccggtcaaaggcattaccaacctgaataatatggcgatgattaatgtttcaggg
ccaggaatgaaagggatggtcggtatggctgcccgcgtctttgcggtgatgtcgcgcagc
ggtatttcagtggtgctaatcactcagtcctcttctgaatacagcatcagtttttgtgtg
ccgcaaggtgagttattgcgcgcccgccgagcgctggaagatgagttttatctggagttg
aaagacggtgtcttggatcctctggatgtgatggaacatctggcaattatctctgtggtc
ggtgacggtatgcgcaccctgcgcggtatttctgcccgtttcttctcggctctggcgcgc
gccaacatcaatattattgctatcgctcaaggctcgtctgagcgctctatttctgtggtt
gtcaataatgatgcggtcactaccggggtgcgagtttgccaccagatgctgtttaacacg
gatcaagtcattgaggtgtttgtcattggcgtgggtggtgtggggggcgcattaatcgaa
caaatctatcgccagcaaccgtggttgaaacagcgtcatattgatttacgtgtttgtggt
atcgcgaattccaaagccatgttgaccaacgtgcatggcattgcattagataactggcgt
caggaactggctgaagttcaggagccgtttaacctgagccgcttgatccgtctggttaaa
gagtatcacttactgaacccggtcattgttgactgtacctcaagccaggcggttgctgat
caatatgctgatttcctgaccgatggcttccatgtggtgacgccaaacaagaaagccaac
acttcatcaatgaattattaccgccaaatgcgtgccgctgcgacgaaatcgtgccgtaaa
ttcttgtatgacacaaacgttggggcggggctaccggtgatcgagaacttacagaacctg
ctcaatgcgggtgatgaactgatgcgcttcaccggtattctgtccggttcactttccttc
atcttcggtaagctagatgaggggatgtcattgtcagaggcaacacggcaagctaaggcg
ttggggtataccgaacccgatccacgtgatgatctctctgggatggatgttgcccgtaaa
ttgttgattttggcccgtgaagcagggtacaaacttgagttggctgatatcgaggttgag
tccgtcttaccagcaagctttgatgcttcaggtgatgtggatactttcctggcgcgcctg
ccatcattggatgctgaatttacccgcttggtagcgaatgctgcggagcagggcaaagtg
ctacgttatgtcggagtgattgaagacgggcgttgtaaagtgcggatggaggcagttgac
ggtaacgacccgttgtataaagttaagaatggcgagaatgcgttggctttctatacccgc
tattatcagccaattccgttggtgctacgcggttatggcgcaggcaatgatgtgactgcc
gctggggtgtttgccgatcttttacgcacattatcatggaagttgggagtttaa
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