Yersinia pseudotuberculosis IP 32953 (serotype I): YPTB0602
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Entry
YPTB0602 CDS
T00195
Symbol
thrA
Name
(GenBank) bifunctional ThrA; aspartokinase I and homoserine dehydrogenase I (C-terminal)
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
yps
Yersinia pseudotuberculosis IP 32953 (serotype I)
Pathway
yps00260
Glycine, serine and threonine metabolism
yps00261
Monobactam biosynthesis
yps00270
Cysteine and methionine metabolism
yps00300
Lysine biosynthesis
yps01100
Metabolic pathways
yps01110
Biosynthesis of secondary metabolites
yps01120
Microbial metabolism in diverse environments
yps01230
Biosynthesis of amino acids
Module
yps_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
yps_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
yps_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
yps00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
YPTB0602 (thrA)
00270 Cysteine and methionine metabolism
YPTB0602 (thrA)
00300 Lysine biosynthesis
YPTB0602 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
YPTB0602 (thrA)
Enzymes [BR:
yps01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
YPTB0602 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
YPTB0602 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
CAH19842
UniProt:
Q66ET9
LinkDB
All DBs
Position
710712..713171
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AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANAERFMRVADIIESNARQGQVATVLSAPAKITNHLVAMIDKMVAGQDI
SPNISDAERIFAELLRGLADTQPGFDYDRLKALVGHEFAQLKHLLHGISLLGQCPDSINA
SIICRGEKLSIAIMEALFQAKGYHVTVINPVEKLLAQGHYLESTVDITESTRRIGASGIP
SDHIILMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIARFQIPCLIKNTSNPQAPGTLIGGESI
DEDSPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRSGISVVLITQSSSEYSISF
CVPQGELLRARRALEDEFYLELKDGVLDPLDVMEHLAIISVVGDGMRTLRGISARFFSAL
ARANINIIAIAQGSSERSISVVVNNDAVTTGVRVCHQMLFNTDQVIEVFVIGVGGVGGAL
IEQIYRQQPWLKQRHIDLRVCGIANSKAMLTNVHGIALDNWRQELAEVQEPFNLSRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLTDGFHVVTPNKKANTSSMNYYRQMRAAATKSC
RKFLYDTNVGAGLPVIENLQNLLNAGDELMRFTGILSGSLSFIFGKLDEGMSLSEATRQA
KALGYTEPDPRDDLSGMDVARKLLILAREAGYKLELADIEVESVLPASFDASGDVDTFLA
RLPSLDAEFTRLVANAAEQGKVLRYVGVIEDGRCKVRMEAVDGNDPLYKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaatttggcgggacatcagtggcaaatgccgagcgctttatgcgtgtt
gccgatatcatcgaaagtaatgcgcgtcagggacaagtggctacggtgttatccgctccc
gcgaagataacgaaccatctcgttgccatgatcgataaaatggtcgcagggcaagatatc
tccccgaacatcagcgatgctgagcggatttttgctgagttattgcgtggattagctgat
actcagccaggctttgattatgatcgcctaaaagccttggtcggccatgagtttgcgcaa
ctcaaacacctgctacacggtatttcgttgttggggcagtgcccagacagcattaatgcc
tcaattatctgccgtggcgaaaaactctccatcgccattatggaggcgttatttcaggct
aagggttatcacgttacggtgattaatccagtcgaaaaattgttggcgcagggccattat
ctcgaatccactgttgatatcacggagtctacccgccgtatcggtgccagcggtattcca
tctgatcacatcatcctgatggctggttttactgcgggtaatgataaaggtgaattggtg
gtgttggggcgtaatggctctgattattccgctgccgtgctggctgcttgcttacgggca
gattgttgtgagatttggaccgatgtcgacggggtctatacttgtgacccgcgtaccgtt
ccagatgccagattactgaaatcgatgtcataccaagaggcaatggagctttcctatttt
ggtgctaaagttcttcaccctcgcactatcgctcctattgcccgcttccaaattccttgt
ctgataaaaaacacctctaacccgcaagcccccggtaccttgattggtggtgaaagcatt
gatgaggattctccggtcaaaggcattaccaacctgaataatatggcgatgattaatgtt
tcagggccaggaatgaaagggatggtcggtatggctgcccgcgtctttgcggtgatgtcg
cgcagcggtatttcagtggtgctaatcactcagtcctcttctgaatacagcatcagtttt
tgtgtgccacaaggtgagttattgcgcgcccgccgagcgctggaagatgagttttatctg
gagttgaaagacggtgtcttggatcctctggatgtgatggaacatctggcaattatctct
gtggtcggtgacggtatgcgcaccctgcgcggtatttctgcccgtttcttctcggctctg
gcgcgcgccaacatcaatattattgctatcgctcaaggctcgtctgagcgctctatttct
gtggttgtcaataatgatgcggtcactaccggggtgcgagtttgccaccagatgctgttt
aacacggatcaagtcattgaggtgtttgtcattggcgtgggtggtgtggggggcgcatta
atcgaacaaatctatcgccagcaaccgtggttgaaacagcgtcatatcgatttacgtgtt
tgtggtatcgcgaattccaaagccatgttgaccaacgtgcatggcattgcattagataac
tggcgtcaggaactggctgaagttcaggagccgtttaacctgagccgcttgatccgtctg
gttaaagagtatcacttactgaacccggtcattgttgactgtacctcaagccaggcggtt
gctgatcaatatgctgatttcctgaccgatggcttccatgtggtgacgccaaacaagaaa
gccaacacttcatcaatgaattattaccgccaaatgcgtgccgctgcgacgaaatcgtgc
cgtaaattcttgtatgacaccaacgttggggcggggctaccggtgatcgagaacttacag
aacctgctcaatgcgggtgatgaactgatgcgcttcaccggtattctgtccggttcactt
tccttcatcttcggtaagctagatgaggggatgtcattgtcagaggcaacacggcaagct
aaggcgttggggtataccgaacccgatccacgtgatgatctctctgggatggatgttgcc
cgtaaattgttgattttggcccgtgaagcagggtacaaacttgagttggctgatatcgag
gttgagtccgtcttaccagcaagctttgatgcttcaggtgatgtggatactttcctggcg
cgcctgccatcattggatgctgaatttacccgcttggtagcgaatgctgcggagcagggc
aaagtgctacgttatgtcggagtgattgaagacgggcgttgtaaagtgcggatggaggca
gttgacggtaacgacccgttgtataaagttaagaatggcgagaatgcgttggctttctat
acccgctattatcagccaattccgttggtgctacgcggttatggcgcaggcaatgatgtg
actgccgctggggtgtttgccgatcttttacgcacattatcatggaagttgggagtttaa
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