Zalophus californianus (California sea lion): 113907948
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Entry
113907948 CDS
T07874
Symbol
NOS2
Name
(RefSeq) nitric oxide synthase, inducible isoform X1
KO
K13241
nitric-oxide synthase, inducible [EC:
1.14.13.39
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca00220
Arginine biosynthesis
zca00330
Arginine and proline metabolism
zca01100
Metabolic pathways
zca04020
Calcium signaling pathway
zca04066
HIF-1 signaling pathway
zca04146
Peroxisome
zca04371
Apelin signaling pathway
zca04926
Relaxin signaling pathway
zca05010
Alzheimer disease
zca05014
Amyotrophic lateral sclerosis
zca05022
Pathways of neurodegeneration - multiple diseases
zca05133
Pertussis
zca05140
Leishmaniasis
zca05142
Chagas disease
zca05145
Toxoplasmosis
zca05146
Amoebiasis
zca05152
Tuberculosis
zca05200
Pathways in cancer
zca05222
Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
113907948 (NOS2)
00330 Arginine and proline metabolism
113907948 (NOS2)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
113907948 (NOS2)
04066 HIF-1 signaling pathway
113907948 (NOS2)
04020 Calcium signaling pathway
113907948 (NOS2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
113907948 (NOS2)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
113907948 (NOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113907948 (NOS2)
09162 Cancer: specific types
05222 Small cell lung cancer
113907948 (NOS2)
09171 Infectious disease: bacterial
05133 Pertussis
113907948 (NOS2)
05152 Tuberculosis
113907948 (NOS2)
09174 Infectious disease: parasitic
05146 Amoebiasis
113907948 (NOS2)
05145 Toxoplasmosis
113907948 (NOS2)
05140 Leishmaniasis
113907948 (NOS2)
05142 Chagas disease
113907948 (NOS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
113907948 (NOS2)
05014 Amyotrophic lateral sclerosis
113907948 (NOS2)
05022 Pathways of neurodegeneration - multiple diseases
113907948 (NOS2)
Enzymes [BR:
zca01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
113907948 (NOS2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
113907948
NCBI-ProteinID:
XP_027423547
UniProt:
A0A6J2B020
LinkDB
All DBs
Position
16:18835000..18873337
Genome browser
AA seq
1157 aa
AA seq
DB search
MACPWQFLFKAKSYRFDLTEETDINNNVGKASRVPSSLVTQDGPQCRGLGKHRNESPQSL
TGTVKTSPESLIKLDVPPSACPRHVRIKNWGSGMTFQDTLHHKAKGDLACKSKACLGAIM
NPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ
LTADELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAKEMFEHICRHLRYATNNGNI
RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGTILGDPASVEFTQLCIDLGWKPKYS
RFDVVPLVLQADGQDPEFFEIPPDLVLEVPMEHPKYEWFRELQLKWYALPAVANMLLEVG
GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVVEINV
AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEM
LNYVLSPFYYYQVEAWKTHTWQDEKRRPRRRKIPFKVLVKAVFFASMLMRRTMVSRVRAT
ILFATETGKSETLARDLGALFSCAFNPKVLCMDEYKLSHLEEEQLLLVVTSTFGNGDSPG
NGEKLKKSLFMLKELTNKFRYAVFGLGSSMYPQFCAFAHDIDQKLSHLGASQLAPTGEGD
ELSGQEEAFRSWAVQTFKAACEMFDVRGKHHIQIPRLYTCSVTWDPQHYRLVQDSQPLDL
NKALSSMHAKNVFTLRLKSQRNLQSPQSSRTTLLVELSCEDSHGLSYMPGEHLGVCPGNQ
PALVRGILERVVDGPAPHQPVQLERLSESGSYWVRDKRLPPCSLSQALTYFLDITTPPTQ
VLLRRLAQLATEEAERQRLKILCQPSEYNKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQL
PILKPRYYSISSSRDHTPTEVHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDSVPCF
LRSAGNFQLPEDPSHPCILIGPGTGIAPFRGFWQQRLHDTKHKELQAGRMTLVFGCRRPD
EDHLYREEMLEMAQNGVLHEVHTAYSRLPGQPKVYVQDILRQRLASEVLRVLHEEHGHLY
VCGDVRMARDVAHTLKLLVAAKLSLSEEQVEDYFFQLKSQKRYHEDIFGAVFPYEVKKDG
AARQPSDPRVPTAHGRS
NT seq
3474 nt
NT seq
+upstream
nt +downstream
nt
atggcctgtccctggcagttcttgttcaaggccaaatcctaccggttcgacttgaccgag
gaaacagacatcaacaacaatgtggggaaagccagccgggtcccctccagtctagtgaca
caggatggcccccagtgtcgtggcctcggcaagcaccggaatgagtccccccagtccctc
acggggacggtcaagacgtctccagaatccctgatcaaactggatgtgcccccatcggcc
tgcccgcggcatgtgaggatcaaaaactggggcagcgggatgaccttccaagacacactt
caccacaaggccaagggggatctcgcttgcaagtccaaggcttgtctgggagccatcatg
aaccccaaaagtttgaccagaggacccagggacaagcctacccccccagacgagctccta
cctcaagctattgaatttgtcaaccagtattacggttccttcaaagaggcaaaaatagag
gaacatctggccagggtggaagcggtaacaaaggagatagaaacaacaggaacctatcag
ctgacagcggatgagctcatctttgctaccaagcaggcctggcgcaatgccccccgctgc
atcgggaggatccagtggtccaacctgcaggtctttgatgcccggagctgttccactgcc
aaggaaatgtttgagcacatctgcagacacctgcgttatgccaccaacaacggcaacatc
aggtcggccatcactgtgtttccccagcggagtgatgggaagcatgacttccgggtctgg
aatgctcagctcatccggtatgccggctaccagatgccggacggcaccatcctgggggac
cccgccagcgtggagttcacccagctgtgcatcgacctgggctggaagcccaagtacagc
cgcttcgatgtggtgcctctggtgctacaggcggacggccaagaccctgagttcttcgaa
attccacctgaccttgtgctcgaggtgcccatggaacatcccaagtatgagtggttccgt
gagctgcagctgaagtggtatgccctgcccgcagtggccaacatgctgctcgaggtgggt
ggcctcgagttcccagggtgccccttcaacggctggtacatgggcacggagatcggggtc
cgggacttctgtgatgtccagcgctacaacattctggaggaagtgggcagaaggatgggc
ctggaaacgcataagctggcctcactctggaaggaccgggctgtcgttgagatcaatgtc
gctgtgctccacagcttccagaagcagaatgtgaccatcatggaccaccactcagctgca
gagtccttcatgaagtacatgcagaacgagtaccgctcccgagggggctgcccagctgac
tggatttggctggtacccccgatttctgggagcatcactcctgtgttccaccaggagatg
ttaaactatgtcctctcccctttctactactaccaggtggaggcctggaaaacccacacc
tggcaggacgagaagcggagaccccggagaagaaagattccgttcaaagtcttggttaaa
gctgtgttcttcgcctccatgctgatgcgcaggaccatggtgtcccgggtcagggccaca
atcctttttgcgacggagacaggaaagtcagaaacgctggcccgggacctgggggccttg
ttcagctgtgccttcaaccccaaggtcctctgcatggacgagtacaagctgagtcatctg
gaggaggagcagctgcttctggtggtgaccagcacgtttgggaatggagactcccccggc
aacggagagaaactgaaaaaatctctcttcatgctgaaagagcttaccaacaagttcagg
tatgctgtgtttggcctcggctccagcatgtaccctcagttctgtgcctttgctcatgac
atcgaccagaagctgtcccatctgggggcctctcagctcgccccaacaggggaaggggac
gagctcagtggacaggaggaagccttccgcagctgggccgtgcaaaccttcaaggcggcc
tgtgagatgttcgatgtgcgaggcaaacaccacattcagatccccaggctctacacctgc
agtgtgacctgggacccacagcactacaggctcgtgcaggactcgcagcctctggacctc
aacaaagccctcagcagtatgcacgccaagaacgtgttcaccctgaggctcaaatcacaa
cggaatctacagagtccccaatccagccgcaccaccctcctggtggagctctcctgtgag
gacagccacgggctgagctacatgcccggagagcacctcggggtttgcccgggcaaccag
ccggccctggtgcgaggcatcttggagcgagtggtagatggccctgcaccccaccagcct
gtgcaactggagaggctcagtgagagtggaagctactgggtcagagacaaacggctgccc
ccatgctcactcagccaggccctcacctacttcctggacatcaccaccccccctacccag
gtgctgctccgaaggctggcacagctggctacggaagaggccgagaggcagaggctgaag
atcctgtgccagccctcagaatacaacaagtggaagttcaccaacagccccacatttctg
gaggtgctagaggagttcccatccctgcgggtgtctgctggcttcctactctcccagctc
cctattctgaaaccccggtactactccatcagctcctctagggaccacacacccacggag
gtccacctcacagtggctgtgctcacataccgcactcgagatggccaaggtcccttgcac
catggtgtctgtagcacatggctcagcagcctgaagccccaagactcagtaccctgcttc
ctgagaagtgccggcaacttccagctccccgaggacccctcccatccttgcatcctcatc
ggacctggcacaggcattgcccccttccgtggtttctggcagcagcggctccatgacacc
aagcacaaagagctccaggctggccgcatgaccctggtattcgggtgccgccgcccagat
gaggaccacctgtatcgggaagagatgttggagatggcccagaatggggtgctgcatgag
gtgcacacagcctattctcgcctgcctggccagcccaaggtctatgttcaagacatcctg
cggcagcggctggccagcgaggtgctccgcgtgctccatgaggagcatggccacctttat
gtctgtggggacgtgcgtatggcccgggatgtggcccataccctgaagctcctggtggct
gccaagctgagcctgagtgaggagcaggtggaggactattttttccagcttaagagccag
aagcgctatcatgaagatatctttggcgctgtgtttccctatgaggtgaaaaaagatggg
gcagcaaggcagcccagcgatcccagagttccaacagcccacgggagaagttaa
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