KEGG   Zalophus californianus (California sea lion): 113908186
Entry
113908186         CDS       T07874                                 
Symbol
DNAH2
Name
(RefSeq) dynein heavy chain 2, axonemal isoform X1
  KO
K10408  dynein axonemal heavy chain
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca04814  Motor proteins
zca05014  Amyotrophic lateral sclerosis
zca05016  Huntington disease
zca05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:zca00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    113908186 (DNAH2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    113908186 (DNAH2)
   05016 Huntington disease
    113908186 (DNAH2)
   05022 Pathways of neurodegeneration - multiple diseases
    113908186 (DNAH2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:zca03037]
    113908186 (DNAH2)
   04812 Cytoskeleton proteins [BR:zca04812]
    113908186 (DNAH2)
Cilium and associated proteins [BR:zca03037]
 Motile cilia and associated proteins
  Dynein arm
   113908186 (DNAH2)
Cytoskeleton proteins [BR:zca04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     113908186 (DNAH2)
SSDB
Motif
Pfam: AAA_6 DHC_N2 DHC_N1 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 DYH2-5-8_CC Dynein_AAA_lid AAA_lid_1 DYN_lid AAA AAA_22 AAA_16 TsaE nSTAND3 NB-ARC Mg_chelatase Sigma54_activat nSTAND_NTPase5 Sigma54_activ_2 DUF3452 DUF815 AAA_2 IL2 Trypan_PARP Bac_DnaA Guanylate_kin
Other DBs
NCBI-GeneID: 113908186
NCBI-ProteinID: XP_035580681
UniProt: A0A6P9FHX3
LinkDB
Position
16:2695058..2776436
AA seq 4516 aa
MSSKAEKRRKVSARGSASRGGARRRDGQAALASQAALASQAAENPLSSDEPELEPEPLKE
EPEPPLEEPEVEKEELPEPEVDVKPLFLSRAVLTGLADAAWTVEHDAILEHFAQDPSELI
LTIFIDPYMGLKLDLGMPVQTQNQIVYFIRCVPVPITPENFEATVQYGTVRGSYIPALLR
LLSGVFAPQIFTNTTWPESIRNHFASHLHRFLACLTDTRYKLEGHTVLYIPAEAMNMAPE
VVVKDKELVQRLETSMIHWTRQIKEVLSAQESVETGENLGPLEEIEFWHNRCMDLSGISK
QLMKQGVKHIESILRLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAYMR
PKDISSKLPKLISLIRIIWVNSPHYNTRERLTSLFRKMSNEIIRLCCHAISLDRIFEGHV
TSSKEDLQGCIACCQAWKDHYLRAVQMHTQFSSAGWVLDQTSIFAQVDAFVQRCKDLIEV
CDCQYHFARWEDGKQAPLPRFFGAQGPQITRNLLEIEDIFHKNLQVLRAVRGGILDVKNT
SWHEDYNRFRTGVKDLEVMTQNLITSAFELVRDVEQGVLLLDTFHRLATREAIKRTYDKK
AVDLYMLFNSELALVNRELNKKWSYLEPYMAQYSGRAHWMRLLRHRIDRVMNCLSSAHFL
PHIGTGEESVHTYQQMVQAIDELVRKTFQDWTLTLDKDCIRRLDTPLLRISQEKAGMLDV
NFDKSLLILFVEIDYWERLLFETPHYVMNVAKREEDLRILRENLLLVARDYNRIIAMLSP
DEQALFKERIRFLDKKIHPGLKKLHWALKGASAFFITECRIHASKVQTIVNEFKASTLTI
GWRAQEISETLLVHISGKRVYRDLEFEEDQREHRAAVQQKLMSLHQDVVAIMTNSYEVFK
NDGPEIQQQWVLYTIRLDRMMEDALRLNVKWSLLELSKAINGDGKTTPNPLFRVLVILQN
DTQGGVAQVEFSPTLQTLAGVVNDIGHHLFSTISVFRHLPEILIRRKFHRDPIHIIVERD
EDIKKIQAQISSGMTNNASLLQNYLKTWDLYREIWEINKDSFIRRYQRLNPPVSSFDADI
ARYTEVANNVQKEETVLNIQFVLLDCSHLKFSLVQHCNEWQNKFTTLLKDMAARRLLELH
TYLQDNGDKISRPPQTLEELGVSLQLMETLQHDLPDLETQIPPIHEQFTILEKYEVPVQE
NVLEMLDSLNGEWVIFQQILLDSEQMLKKHKEKFKTGLIHSADDFKKKAHNLLEDFESKG
PFTSNVGHQAALEQIAQVRAMLNAMREEENSLRSNLGIFKIEQPASKDLQNLEKELDALQ
QVWEITRDWEENWNQWKMGRFLTLQTEAMETMAHGLFRRLTRLAKEYKDRNWEIIETTRS
KIEQFKKTMPLISDLRNPALRERHWDQVRDEIQREFDQESDRFTLEQIVDLGMDQHVEKI
GEISASATKELAIELALQNIAKTWSVIQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALS
TMKASRFVKAFEKEADRWERCLSLILEGVEMLLTVQRQWMYLENIFLGEDIRKQLPSESA
LFDQVNNNWKSIMDRMSKDSNALRSTHHPGLLDTLTEMNTVLEDTQKSLDMYLETKRRIF
PRFHLLSTDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRMQKVGGPSGKWEAVGMFSGDG
EYVDFLHAVLLEGPVESWLGDVERTMRVTLRDLLRNCRLALKKFLNKRDKWVKEWAGQVL
ITASQIQWTADVTKCLLAAKERGDKKILKVMKKKQVSVLNKYSEAIRGNLTKIMRLKIVA
LVTIEVHARDVLEKLYKSGLVDVSSFEWLSQLRFYWEKELDDCVIRQTNTQFQHSYEYLG
NSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSE
GLDYKSMGRMYSGLAQTGAWGCFDEFNRINVEVLSVVAQQILSILSALAAGLTRFYFEGF
EINLAWTCGIFITMNPGYAGRTELPDNLKSMFRPIAMVVPDSALIAEIILFGEGFGNCKI
LAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRVQPDLSDEEVLLLSMRDMN
IAKLTSVDVPLFNAMVQDLFPNIEVPVVDYGKLRDVIEQEIQDMGLQSTPFTLTKVIQLY
ETKNSRHSTMIVGCTGSGKTTSWRILQASLSSLCRAGEPNFNIVREFPLNPKALSLGELY
GEYDLNTNEWTDGVLSSVMRTACADEKPDEKWILFDGPVDTLWIESMNSVMDDNKVLTLI
NGERIAMPEQVSLLFEVENLAVASPATVSRCGMVYTDYSDLGWKPYVQSWLEKRPKAEAE
PLQRMFEKFINKMLAFKKDFCNELVPIPEYSGIISLCKLYSALARPENGVNPADGENYVS
MVELTFVFSLIWSVCASVDEEGRKKMDSYLREMEGSFPNKDTVYEYFVDPKMRTWTSFEN
KLPKSWRYPPNSPFYKIMVPTVDTVRYNYLVSALMANQNPVLLVGPMGTGKTSIAQSVLH
SLPSSQWSVLIINMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKD
MFGSQPPLELIRLWIDYGFWYDRMKQTIKYIRDMFLMAAMGPPGGGRTVISPRLQSRFNI
INMTFPTGSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDLYNTVVQRFLPTPAKIH
YLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLVDAADTEAFVGILSD
KLGSFFDLTFHNICPSKRSPIFGDFMREPKVYEDLADPAVLKAAMETALHEYNLSPSVVP
VQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICEYVTFQIEVTKQ
YRKQEFREDIKRLYRQAGVELKATSFLFVDTQIADESFLEDINNILSSGEVPNLYKTDEF
EEIQAHIVEQAKAEQVSQSSDSLFAYLIERVRNNLHIILCLSPVGDPFRNWIRQYPALVN
CTTINWFSEWPHEALLEVAEKYLMGVDLGAQENIHRKVAKIFVTMHWSVAQYSQKMLLEL
RRYNYVTPTNYLELVSGYKRLLGEKRQELLDQANKLRTGLFKIDETREKVEVMSLELEDA
KKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAIEEVKCQALADNAQKDLEEA
LPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQN
FIKSLIHFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYR
VVEPKRIRMKAALAQLQEKQAALAEAQEKLREVAEKLETLKKQYDEKLAQKEELRKKSEE
MEVKLERAGLLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDE
IVNQIWMKKIWELQVPCSPRFTFDNFLSNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRW
ALMIDPQAQALKWIKNMEGNQGLQIIDLQMSDYLRILENAIQFGYPVLLQNVQEYLDPTL
NPVLNKSVARIGGRLLIRIGDKEVEYNTNFRFYITTKLSNPHYSPEISAKTTIVNFAVKE
QGLEAQLLGIVVRKERPELEEQKDSLVISIAAGKRKLKELEVEILRLLNEATGSLLDDVQ
LVNTLRTSKTTATEVTEQLETSETTEINIDLAREAYRPCAQRASVLFFVLNDMGRIDPMY
QFSLDAYISLFILSIDKSHRSSKLEDRIDYLNEYHTYAVYRYTCRTLFERHKLLFSFQMC
AKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCPSWLADAYWDNITELDKLTNFHGLM
NSFEQYPRDWHLWYTNATPEKATLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIVSN
LGSRFIEPPVLNMKLVMEDSTPRTPLVFILSPGVDPTSALLQLAEHTGMAQRFHALSLGQ
GQAPIAARLLREGVVQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSSPH
PDFPISILQASIKMTTEPPKGLKANMTRLYQLMTEAQFSRCSKPAKYKKLLFALCFFHSV
LLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGVNYGGHVTD
DWDRRLLTTYINDYFCDQSLSTPFYRLSVLEAYFIPKDGSLASYKEHISMLPSMDPPEAF
GQHPNADVASQITEARTLFETLLSLQPQITPTRAGGQSREEKVLELAADVKQKIPEMIDY
EGTRKLLAMDPSPLNVVLLQEIQRYNKLMETILSSLTDLEKGIQGLIVMSTSLEEIFNCI
FDAHVPPLWGKAYPSQKPLASWTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTA
VLQSSARQNNIPVDNLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEA
EPMQLVCLMPTIHFRPTESRKKSAKGMYSCPCYYYPDRAGSADRASFVISIDLRSGTMTP
DHWIKRGTALLMSLDN
NT seq 13551 nt   +upstreamnt  +downstreamnt
atgtccagcaaagcggagaagaggaggaaagtgagtgcccggggaagtgccagccgcgga
ggcgcccgcaggagagatggtcaggcggcgctggcctcgcaggcggcgctggcctcgcag
gctgcagagaaccccctgtcctctgatgagcctgagctggagcctgagcccctcaaagag
gagcctgagccgccattggaggaacccgaagtagagaaggaagaattaccggagcccgag
gtggatgtgaagcccctcttcctgtcccgagctgtgctgacaggactagcagatgctgct
tggacggtggagcatgatgccattctggaacactttgcccaggacccttcggagctcatc
ctcaccatcttcatcgacccctacatggggctgaagctagatctgggcatgcctgttcag
acccagaaccagattgtctacttcattcgctgcgtaccagttcccatcaccccggagaac
tttgaggcaactgtgcagtatgggaccgtgcggggttcctacatcccggccctgctccgg
ctgctcagtggtgtctttgcccctcagatctttacaaacacaacctggccagagagtatt
cggaatcattttgcttctcatctgcacagattcttggcttgcctcacagatactcgatac
aaactggaggggcacaccgttctctacattcctgcagaggccatgaacatggcgccggag
gtggtggttaaggacaaagagctggtacagcggctggagacctccatgatccactggacc
cggcagataaaggaggtgctcagtgcccaggagtctgtggagacaggagaaaatttaggt
cctctggaggagattgagttctggcacaaccgatgcatggacctgtctggcatcagtaag
cagctgatgaagcagggagtgaagcacattgaatccatcctgagacttgccaagtcctcc
tacttggcgccctttatgaaactggcccagcagatccaggatggttctcgtcaagcacag
tcaaacctgacgtttttgtcaattctgaaggagccctaccaggaattggcctacatgcgg
cctaaggacatctccagtaagctccccaagttgatcagtctcatccgcatcatctgggtc
aactctccccactacaacactcgggagagactgacctccctcttccgaaagatgagcaac
gagatcattcgcttgtgctgccacgccatctctctggaccgcatctttgagggccatgtc
acttccagcaaggaggacctgcagggctgcattgcctgctgtcaggcctggaaagatcac
tacctgcgggccgtgcagatgcatacccagttctcgagtgcgggctgggtgctcgaccag
accagcatatttgcccaggtggacgcctttgtgcagcgttgcaaggacctcattgaggta
tgcgactgccagtaccattttgcccgctgggaggatggcaagcaggctccgctgcctcgc
ttctttggtgcccaagggccccagatcacgcgcaacttgctggagatcgaggacatcttt
cataagaatctccaggtgctgcgggctgttcgcgggggcatcctggacgtcaagaacacc
tcttggcacgaggactacaacaggtttcgcactggagtcaaagacctggaggtgatgact
cagaacctgatcacctccgccttcgagttggtccgagacgtggagcagggagtgctgctg
ctggacaccttccacaggcttgccacgcgggaggccatcaagcgaacctacgacaagaag
gcggtggatctctatatgctgttcaatagcgagctggccctggtgaaccgtgagctgaac
aagaaatggtcatacctggagccctacatggcccagtactctggtcgggcccactggatg
cggctcctgcggcaccgcatcgacagggtcatgaactgtctatccagtgctcacttcctg
ccccacattggaacgggagaggagagcgtgcacacctatcagcagatggttcaggccatc
gatgaactggttcgaaaaaccttccaagactggacgttaacgctggacaaggactgtatc
cggcggctggacacgccactgttacgaatcagccaggagaaggcgggcatgctggatgtc
aactttgacaagtccctactgattctctttgtggagattgactactgggaacggctgctc
tttgagacgccccactacgtgatgaatgtagccaagcgggaggaggacctgcgcattctt
cgggaaaacctgttgcttgtggctcgagactacaatcggatcattgctatgctgtcccca
gatgagcaggccctcttcaaagaacgtatccgattcctggataagaagatccaccctgga
ctcaagaaactgcactgggccttgaagggggccagcgccttcttcatcacagaatgccga
atacacgccagcaaggtgcagaccatagtgaatgagttcaaggcctccactctgaccatt
ggctggcgagcccaggagatatctgagacgctgttggtgcacatcagcggcaaacgggta
tacagggacctggaatttgaggaggaccagcgggagcaccgggcggccgttcagcagaaa
ttgatgagcctgcaccaggacgtggtggccatcatgaccaactcctacgaagtcttcaag
aatgacggccctgagatccagcagcagtgggtgctgtacacgattcggctggaccgcatg
atggaggatgccctgcgtctgaatgtgaagtggtcgctgctggagctgtccaaggccatc
aacggggacgggaagaccacgcccaaccccctcttccgagtcctggtcattttgcagaat
gacacacagggaggtgtggcacaggtggaattctcacccactctgcagactctggcaggt
gtggtcaatgacattggccaccacctcttctccaccatctctgtcttccgccacctcccc
gaaattctcatcaggcgcaagtttcatcgtgaccccatccatataatcgtggagcgagac
gaggacatcaagaagatccaggcccagatcagcagcggcatgaccaacaacgcgagcctg
ctgcagaactacctcaagacctgggatttgtatcgggagatctgggagatcaacaaggac
tctttcattcgccgctaccagcgtctcaacccccccgtctcgtcttttgacgctgacatt
gcccgctacacggaggtggctaacaacgtgcagaaggaggagaccgtgctcaacatccag
ttcgtgctgctggactgctcccacctcaagttctcgctggtgcagcattgcaacgagtgg
cagaacaagttcacgaccctgctcaaggatatggcggcccggcgcctcctggagctccac
acctacctgcaggacaacggggacaaaatcagccgccctccccagaccctggaggaactg
ggggtcagtttgcagctcatggagaccctgcagcatgacctgcccgacctggagacccag
atcccccccatacacgagcagttcaccattctcgagaagtacgaggtgccggttcaggag
aacgtcctagagatgctggacagtctcaacggggagtgggtcatcttccaacaaatcctg
ctggatagtgagcaaatgctgaagaaacacaaggagaaattcaagacaggcctcatccac
tcagcggatgacttcaagaagaaagcgcataatctcctggaagactttgaatccaaaggc
cccttcaccagtaacgtgggacatcaggcggccttggagcagatcgcccaggtgcgggcc
atgctgaatgccatgcgggaagaagaaaacagtctccgctccaacctgggcatcttcaag
atcgagcagccagcctccaaggacctgcagaacctggagaaggagctggatgcgctgcag
caggtgtgggagatcacacgggactgggaggagaactggaaccagtggaagatgggccgg
ttcctgacgctgcagacggaggccatggaaacgatggcgcatgggctcttccgccgtctc
accaggctggccaaagagtacaaggaccgcaactgggaaattatcgaaaccactcgctcc
aaaatagagcagttcaagaagaccatgcccctcatctcagaccttcgcaaccccgccctt
agagagaggcactgggatcaggtcagagatgagatccaacgggagtttgatcaggaatct
gaccgcttcaccttggagcagattgtggaccttgggatggaccagcatgtggagaaaatt
ggggagatctctgcgtcggccaccaaagagctggctatagaattggcattacagaacatt
gccaagacctggagcgtgatccagctagacatagttccctataaggacaagggccatcac
cgactccgaggcacagaggaggtattccaggccctggaagataaccaggtggctctgtct
accatgaaggcctctcgttttgtcaaggcctttgagaaggaagcggaccgctgggagcgc
tgcctctccctcatcttggagggcgttgagatgttgcttacggtacagcgccagtggatg
tacctagagaatatcttcctcggagaggacatccgtaagcagctgcccagcgaatcagcc
ctgtttgaccaggtcaacaacaactggaaatccatcatggaccggatgagcaaggacagc
aatgcgctgcggagcacccaccatccaggcctgctggacacgctgacagaaatgaacaca
gttctggaagacactcagaagtctctggatatgtacctagagaccaagcgccgtatcttt
ccgcgcttccacctcctgtccaccgatgacctcctggagattctaggccagtcccgcaac
ccagaggctgtgcagccgcacctcaaaaaatgctttgacaacatcaaattgctgagaatg
cagaaggttgggggacccagtggcaaatgggaagccgtgggaatgttctcaggtgacggc
gagtacgttgacttcctccacgccgtccttctggaagggcctgtggagtcctggcttggt
gacgtggagcggaccatgagggtgaccctacgggaccttctccggaactgtcgcctggcc
ctcaagaagtttcttaacaagagggacaagtgggtgaaggagtgggctggccaggtgttg
atcaccgccagtcagatccagtggacggctgacgtcaccaagtgcctgctggcagctaag
gagcgcggagacaagaaaatcctcaaggtcatgaagaagaagcaggtgtccgtcctgaac
aagtattcggaagccatcagggggaacctgaccaaaatcatgcggctgaaaattgtggcg
ctggtgacaatagaagtccatgcccgggacgtgctggagaagctgtacaagagcggcctc
gtggacgtcagctccttcgagtggctcagtcagctgcgcttctactgggagaaggagctg
gacgactgcgtgatccgccagaccaacacacagttccagcacagctacgagtacttgggg
aactccggccggctggtcatcaccccgctgaccgacaggtgttacatgactctgaccaca
gccctgcacctgcatcgggggggctcccccaaaggcccagcgggcacgggcaagacagag
accgtcaaggatctgggcaaggccctcggcatatacgtcatcgtggtcaactgctccgag
ggcctggactacaagtccatgggcaggatgtactcgggtctggctcagaccggcgcctgg
ggctgctttgacgagtttaaccgcatcaacgtggaggtgctgtcggtggtggcccagcag
atcctgtccatcctgtcggccctggccgccggcctcacccgcttctacttcgagggcttc
gaaataaacctggcgtggacctgtgggatcttcatcaccatgaaccccggctatgccggt
cgcacggagctgccagataacctgaaatccatgttccgccccattgccatggtggtgcct
gattctgctcttattgcagagatcatcctctttggggagggctttggcaactgcaagatt
ctggccaagaaggtgtataccctctactcactggccgtgcagcagctgtccagacaggac
cattacgacttcggcctgcgcgccctcacctccctcctgcgctatgcgggcaagaagcgc
cgcgtgcagccggatctgtctgatgaggaggttctgctgctctcaatgcgagacatgaac
atcgccaagctcacctcagtcgacgtgccgctcttcaacgccatggtgcaagacctgttc
cccaacatcgaggtgcccgtcgttgactacggcaagctgcgggacgtcatcgagcaggag
atccaggacatgggcctgcagagcacaccgttcaccctcaccaaggtcatccagctctac
gagaccaagaactcccgccactccaccatgatcgtgggctgcacgggcagtggcaagacc
acctcgtggcgcatcctccaggcctccctgtcctccttgtgccgcgccggagagcccaac
tttaacatcgtcagggagttccccttgaacccgaaggcgttgtccctaggggagctgtat
ggggaatatgacctcaacacgaacgagtggacagatggcgtcctgtccagcgtcatgcgg
acggcgtgtgcagatgagaagccagatgagaagtggatccttttcgatggccccgtggac
acgctgtggatcgagagcatgaactcggtcatggacgacaacaaagtcctgaccctcatc
aacggggagcgcatcgcgatgcccgagcaggtgtctctcctgttcgaagtggagaacttg
gccgtggcctctcccgccactgtgtctcgctgtgggatggtctacactgactacagtgac
ctgggctggaagccctacgtgcagagctggctggagaagaggccgaaggccgaggcagaa
ccccttcagcggatgtttgagaagttcattaacaagatgctggccttcaagaaggacttt
tgcaacgagttggtgcccatcccggaatacagcgggatcatctccctctgcaagctctac
tcggccctggccaggccggagaacggggtgaacccagccgacggtgaaaactacgtctcc
atggtggagctgacctttgtgttcagcttgatttggtccgtgtgcgcctccgtggatgag
gagggacgcaagaagatggacagttacctccgagagatggagggctcctttcccaataag
gacacagtgtacgagtacttcgtggaccccaagatgcgcacctggacgtcatttgagaat
aagctccctaaaagttggcgctaccctcccaactcccccttctataagatcatggtgccc
acggtcgacaccgttcgctacaactacctggtgagcgccctgatggccaaccagaaccct
gtcctgctggtgggtcccatggggactggaaagacatccatcgcccagagcgtcctccac
tccttgccctccagccagtggtcggtgctcatcatcaacatgtctgcgcagaccacatcc
aacaacgtgcagagcatcatcgagagcagggtggagaagcgaaccaagggcgtctacgtg
ccgttcgggggcaagagcatgatcacctttatggatgatctaaacatgccggcgaaggac
atgtttgggtcccagcccccgctggagctgatccgcctctggatcgactacggcttctgg
tacgaccgcatgaagcagaccatcaagtacattcgagacatgttcctgatggctgccatg
ggcccccccgggggcggacggactgtcatttccccgaggctccagagtcgcttcaacatc
atcaatatgaccttccccacagggtcccagatcatccgaatatttggcaccatgatcaat
cagaagcttcaggacttcgaggaggaggtgaagcccattgggaacgtggtgaccgaggcg
accctggacttgtacaacacggtggtgcagcgcttcctgcccacgcccgccaagatccac
tacctcttcaacctccgggacatctccaaggtgtttcagggaatgctcagggccaacaag
gacttccacgacaccaagtccagcatcacacgactctggatccacgagtgtttcagagtt
ttctcggaccggctggtggatgcagcagacacggaggccttcgtgggcatcctcagcgac
aagctcggttccttctttgacctcacatttcataatatttgtcccagcaagcgctctccc
atcttcggggacttcatgagggagcccaaggtgtatgaggacctggccgacccggcagta
ctgaaggcggccatggagacggcgctgcacgagtacaacctgtccccctcagtggtgcca
gtgcagctggtgctcttccgagaggccatcgaacacatcacacggatcgtgcgggtcatt
ggacagcctcggggcaacatgctcttggtgggcatcgggggcagtgggcgccagagtctg
gcccgcctggcctcctccatctgcgagtacgtcaccttccagatcgaggtcaccaaacaa
tatcgaaagcaggagttccgagaagatatcaagcgtctgtaccgccaggcaggagtagag
ctcaaggccacgtccttcctcttcgtggacacccagatcgctgacgagtcgttcctggag
gacatcaacaacatcctgagctcaggcgaggtccccaatctctacaagactgatgaattc
gaagagatccaggcgcacatcgtggagcaggccaaggccgagcaggtgtcccagtcctcc
gacagcctctttgcctacctcattgagcgcgtgcggaacaacctgcacatcattctctgc
ctcagccccgtgggcgaccccttcaggaactggatccgccagtacccggccttggtgaac
tgcacgaccatcaactggttctccgagtggccccacgaggccctgctggaggtggccgag
aagtacctcatgggggtggacctgggggcgcaggagaacatccacaggaaggtggccaag
atctttgtcaccatgcactggtcagtggcgcagtactcccagaagatgctgctggagctg
cggagatacaactacgtcacgcccaccaactacctggagctcgtgtctggatacaagagg
ttgctgggagagaagcggcaggagctgctggaccaggccaacaagctgcggacgggactg
tttaagatcgacgaaaccagagagaaggtggaagtgatgtccctggagctggaggacgcc
aagaagaaggtggctgagttccagaagcagtgcgaggagtacctggtcatcatcgtgcag
cagaagcgagaagcagacgagcagcagaaggcggtcacggccaatagtgagaagattgca
atcgaggaagtcaagtgccaggccctggctgacaatgcccagaaggatctagaagaggcc
ttgccagccctggaggaagccatgcgggccctggagtccctgaacaagaaggacatagga
gagatcaagtcttacggccggccccccgcccaagtggaaatcgtgatgcaggccgtcatg
attcttcgaggcaacgagcccacgtgggcagaggccaagcggcagctaggggagcagaac
ttcatcaagtccctgatccactttgataaagacaatatctcagataaggtcctgaagaaa
attggggcctactgtgcacagccggacttccagcctgacatcatcggcagagtctcactc
gctgccaagtccctgtgcatgtgggtgcgggccatggagctgtacgggcgcctgtaccgc
gtggtggagcccaagcggattcggatgaaggctgccttggcccagcttcaggagaagcag
gcggcgctggccgaggcccaggagaagctgcgggaggtggctgagaaactggagacgctg
aagaaacagtatgacgagaagctggcccagaaggaggagcttcgcaagaagtctgaggag
atggaggtgaagctggagcgtgccgggctgctggtgtccgggctggctggcgagaaggca
cggtgggaggagacagtgcagggcctggaggaggatctgggctacctggtaggtgactgt
ctcctggccgctgccttcctgtcctacatgggccccttcctgaccaactaccgggacgag
atcgtcaaccagatctggatgaagaagatctgggagcttcaggtcccttgctcgcctcgc
ttcacctttgataacttcctgtccaatcctaccaaagttcgagactggaacatccaagga
ttgccctcggatgccttttccaccgagaacggcatcattgtcacccgtggcaacaggtgg
gcgctgatgattgaccctcaggcccaggccctaaagtggatcaagaacatggaaggaaac
cagggcctccagattattgacctgcagatgagcgattaccttcgaattctagaaaacgcc
atccagtttggatatccagtgctgctccagaacgtgcaggaatatctggaccccacactc
aaccctgtgctcaacaaatctgtagctcgaatcggtggtcggctgctgatacgcattgga
gacaaggaggtggagtacaacacaaatttccggttctacatcaccaccaagctctccaac
cctcactacagcccagagatctcggccaagaccaccattgtcaactttgctgtcaaagaa
cagggcctggaggctcagctgctgggcatcgtggtccggaaggagcggccagagctggag
gagcagaaggactcgctggtcatcagtatcgctgccggcaagaggaagctcaaggagctg
gaggtcgagatccttcggctgctgaacgaggccacgggctccctgctcgacgatgtgcag
ctggtgaacaccctccggacctccaagacgacggccaccgaggtgacggagcagctggag
accagcgagaccacagagatcaacatcgacttggcccgcgaggcttaccgcccctgcgcc
cagcgggcctcggtgctgttcttcgtgctcaatgacatgggccgcatcgaccccatgtac
cagttctcgctggacgcctacatcagcctcttcatcctcagcatcgacaagagccaccgc
agcagcaagctggaggaccgcatcgactacctgaacgagtaccacacctacgcagtctac
aggtacacctgccgcacactttttgaacgccacaagctactgttcagcttccagatgtgt
gccaaaatcctggagacctctggcaagctcaacatggatgagtacaacttcttcctgcgc
gggggcgtggtcctggatcgggagggccaaatggataacccgtgtcccagctggctggcg
gatgcttactgggataacatcacagagctggacaaactgaccaacttccacggactcatg
aactcctttgaacagtaccctcgtgactggcacctgtggtacacgaatgccaccccggag
aaggccacgctgccaggtgagtgggagaacgcctgcaatgagatgcagcggatgctgatc
gtccgctccctgcgccaggaccgcgtggctttctgcgtcacctcgttcatcgtgtccaac
ctgggctcccgcttcatcgagccgcccgtgctaaacatgaagctggtgatggaggattcg
accccgcggaccccgctggtcttcatcctgtcccccggcgtggaccccaccagtgccctg
ctccagctggcagagcacacgggcatggcccagcgcttccacgccctgtccctgggccag
ggccaggcccccattgctgctcggctcctccgggagggcgtggttcagggacactgggtg
ttcctagcgaactgccacctgtcactgtcgtggatgcctaatctggacaaactggtggag
cagctgcaggtggaagatcctcacccttctttccgcctctggctcagctccagcccccac
ccggacttccctatctccatcttgcaggccagcatcaagatgaccacagaaccaccaaag
ggcctgaaggccaacatgacacgtctttaccagctgatgacggaagcacagttttcccgc
tgctccaaacctgccaagtataagaagctgctgtttgcactctgcttcttccattctgtg
ttgctggaacgcaaaaagttcctgcagcttggctggaacattatctatggcttcaatgac
tccgactttgaggtgtccgagaacttgctgagtctctatctggatgagtacgaggagaca
ccgtgggatgcactcaagtacctcattgccggcgtcaactacggtgggcacgtcacggac
gactgggaccggcgcctgctcaccacctacatcaacgactatttctgtgaccagtctctg
tcgacccccttttaccggttgtcggtactggaggcttatttcatccccaaagatgggagc
ctggcctcttacaaggagcacatcagcatgttgcccagcatggacccccctgaggccttt
ggccagcaccccaatgcggatgtggcctcccagatcactgaggcacgaactctctttgag
actctgctttccctgcaaccccagattacacccaccagggctggaggccagagccgggaa
gagaaggtcctcgagttggccgctgacgtgaaacagaagatccctgaaatgatcgactat
gaggggacccgaaaactgctggccatggacccctcccccctcaacgtggtccttctgcag
gagatccagagatacaacaagcttatggagaccatcctgtcctcactgacagacctcgaa
aaaggcattcagggcctcatcgtcatgtctacgagcctggaagagattttcaattgcatc
ttcgatgcccacgtccctccactctggggaaaggcttatccctcacaaaagccactggct
tcgtggacccgggacttggccatgcgcgtggaacagtttgagctgtgggccagccgtgcc
cggcctcctgtgatcttctggctgtccggcttcacgtttcccaccggcttcctcactgct
gtgctgcagtcctctgctcgccaaaacaacattccagtggacaacctctcttgggagttc
attgtttccaccgtggacgacagcaacctagtgtatccacccaaggacggcgtctgggtc
cgtggcctgtacctggagggcgccggctgggacaggaagaactcctgcttggtggaggcg
gagcccatgcagcttgtctgcctcatgcccacgatccacttcaggcctacagaaagtcgc
aagaagagcgccaagggcatgtactcctgcccctgctattactaccccgaccgcgccggc
agcgcagaccgagcctcctttgtcatcagcatcgacctccggtccgggaccatgaccccc
gatcactggatcaagaggggcactgctctactcatgagcctggacaactga

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