KEGG   Zalophus californianus (California sea lion): 113908204
Entry
113908204         CDS       T07874                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca01521  EGFR tyrosine kinase inhibitor resistance
zca01522  Endocrine resistance
zca04012  ErbB signaling pathway
zca04066  HIF-1 signaling pathway
zca04140  Autophagy - animal
zca04150  mTOR signaling pathway
zca04151  PI3K-Akt signaling pathway
zca04152  AMPK signaling pathway
zca04211  Longevity regulating pathway
zca04213  Longevity regulating pathway - multiple species
zca04350  TGF-beta signaling pathway
zca04371  Apelin signaling pathway
zca04666  Fc gamma R-mediated phagosome formation
zca04714  Thermogenesis
zca04910  Insulin signaling pathway
zca04931  Insulin resistance
zca05163  Human cytomegalovirus infection
zca05165  Human papillomavirus infection
zca05170  Human immunodeficiency virus 1 infection
zca05200  Pathways in cancer
zca05205  Proteoglycans in cancer
zca05207  Chemical carcinogenesis - receptor activation
zca05210  Colorectal cancer
zca05212  Pancreatic cancer
zca05221  Acute myeloid leukemia
zca05224  Breast cancer
zca05225  Hepatocellular carcinoma
zca05226  Gastric cancer
zca05231  Choline metabolism in cancer
zca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:zca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    113908204 (RPS6KB1)
   04350 TGF-beta signaling pathway
    113908204 (RPS6KB1)
   04371 Apelin signaling pathway
    113908204 (RPS6KB1)
   04066 HIF-1 signaling pathway
    113908204 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    113908204 (RPS6KB1)
   04152 AMPK signaling pathway
    113908204 (RPS6KB1)
   04150 mTOR signaling pathway
    113908204 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    113908204 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagosome formation
    113908204 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    113908204 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    113908204 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    113908204 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    113908204 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113908204 (RPS6KB1)
   05205 Proteoglycans in cancer
    113908204 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    113908204 (RPS6KB1)
   05231 Choline metabolism in cancer
    113908204 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    113908204 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    113908204 (RPS6KB1)
   05212 Pancreatic cancer
    113908204 (RPS6KB1)
   05225 Hepatocellular carcinoma
    113908204 (RPS6KB1)
   05226 Gastric cancer
    113908204 (RPS6KB1)
   05221 Acute myeloid leukemia
    113908204 (RPS6KB1)
   05224 Breast cancer
    113908204 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    113908204 (RPS6KB1)
   05163 Human cytomegalovirus infection
    113908204 (RPS6KB1)
   05165 Human papillomavirus infection
    113908204 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    113908204 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    113908204 (RPS6KB1)
   01522 Endocrine resistance
    113908204 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:zca01001]
    113908204 (RPS6KB1)
Enzymes [BR:zca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     113908204 (RPS6KB1)
Protein kinases [BR:zca01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   113908204 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 113908204
NCBI-ProteinID: XP_027424168
UniProt: A0A6J2B2S8
LinkDB
Position
16:complement(26655756..26707784)
AA seq 525 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
VEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgaggcgacgacggaggcgggacggcttttacccagcgccggacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggaacattgtgagaaatttgaaatttcggaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgggtacttggtaaaggg
ggctatggaaaggtttttcaagtacgaaaagtaacaggagcaaatactgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagaacggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagactggtggaaaactctacctcatccttgagtatctcagcgggggagaatta
tttatgcagttagaaagagagggaatatttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgcttaatcaccaaggtcatgtgaaactgacagactttggactatgc
aaagaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtttggga
gcattaatgtatgacatgctgactggagcacccccgttcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcggcttggagctggtcct
ggggatgctggagaagttcaagctcatccattcttcaggcatattaactgggaagaactg
ctagctcggaaggtggagcccccctttaaacctctgttgcaatctgaagaggatgtgagt
cagtttgattcaaagtttacacgtcagacacctgttgacagcccagatgactcaactctc
agtgaaagtgccaaccaggtctttctgggttttacatatgtggctccatctgtacttgaa
agtgtgaaagaaaaattttcctttgaaccaaaaatccgatcacctcgaagatttattggc
agcccacgaacacctgtcagcccagtcaaattttctcctggggatttctggggaagaggt
gcttcagccagcacggcaaatcctcagacacctgtggaatatccaatggaaacaagtgga
gtagagcagatggatgtgacgatgagtggggaagcttcagcaccacttccaatacgacag
ccgaactccgggccatacaaaaaacaagcttttcccatgatctccaaacgaccagagcac
ctacgtatgaatctatga

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