Zalophus californianus (California sea lion): 113908984
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Entry
113908984 CDS
T07874
Symbol
ADCY4
Name
(RefSeq) adenylate cyclase type 4 isoform X1
KO
K08044
adenylate cyclase 4 [EC:
4.6.1.1
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca00230
Purine metabolism
zca01100
Metabolic pathways
zca01522
Endocrine resistance
zca04015
Rap1 signaling pathway
zca04020
Calcium signaling pathway
zca04022
cGMP-PKG signaling pathway
zca04024
cAMP signaling pathway
zca04062
Chemokine signaling pathway
zca04072
Phospholipase D signaling pathway
zca04081
Hormone signaling
zca04082
Neuroactive ligand signaling
zca04114
Oocyte meiosis
zca04211
Longevity regulating pathway
zca04213
Longevity regulating pathway - multiple species
zca04261
Adrenergic signaling in cardiomyocytes
zca04270
Vascular smooth muscle contraction
zca04371
Apelin signaling pathway
zca04540
Gap junction
zca04611
Platelet activation
zca04713
Circadian entrainment
zca04714
Thermogenesis
zca04723
Retrograde endocannabinoid signaling
zca04724
Glutamatergic synapse
zca04725
Cholinergic synapse
zca04727
GABAergic synapse
zca04742
Taste transduction
zca04750
Inflammatory mediator regulation of TRP channels
zca04911
Insulin secretion
zca04912
GnRH signaling pathway
zca04913
Ovarian steroidogenesis
zca04914
Progesterone-mediated oocyte maturation
zca04915
Estrogen signaling pathway
zca04916
Melanogenesis
zca04918
Thyroid hormone synthesis
zca04921
Oxytocin signaling pathway
zca04923
Regulation of lipolysis in adipocytes
zca04925
Aldosterone synthesis and secretion
zca04926
Relaxin signaling pathway
zca04927
Cortisol synthesis and secretion
zca04928
Parathyroid hormone synthesis, secretion and action
zca04934
Cushing syndrome
zca04935
Growth hormone synthesis, secretion and action
zca04970
Salivary secretion
zca04971
Gastric acid secretion
zca04972
Pancreatic secretion
zca04976
Bile secretion
zca05032
Morphine addiction
zca05163
Human cytomegalovirus infection
zca05166
Human T-cell leukemia virus 1 infection
zca05200
Pathways in cancer
zca05207
Chemical carcinogenesis - receptor activation
zca05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
113908984 (ADCY4)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
113908984 (ADCY4)
04371 Apelin signaling pathway
113908984 (ADCY4)
04020 Calcium signaling pathway
113908984 (ADCY4)
04072 Phospholipase D signaling pathway
113908984 (ADCY4)
04024 cAMP signaling pathway
113908984 (ADCY4)
04022 cGMP-PKG signaling pathway
113908984 (ADCY4)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
113908984 (ADCY4)
04081 Hormone signaling
113908984 (ADCY4)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
113908984 (ADCY4)
09144 Cellular community - eukaryotes
04540 Gap junction
113908984 (ADCY4)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
113908984 (ADCY4)
04062 Chemokine signaling pathway
113908984 (ADCY4)
09152 Endocrine system
04911 Insulin secretion
113908984 (ADCY4)
04923 Regulation of lipolysis in adipocytes
113908984 (ADCY4)
04912 GnRH signaling pathway
113908984 (ADCY4)
04913 Ovarian steroidogenesis
113908984 (ADCY4)
04915 Estrogen signaling pathway
113908984 (ADCY4)
04914 Progesterone-mediated oocyte maturation
113908984 (ADCY4)
04921 Oxytocin signaling pathway
113908984 (ADCY4)
04926 Relaxin signaling pathway
113908984 (ADCY4)
04935 Growth hormone synthesis, secretion and action
113908984 (ADCY4)
04918 Thyroid hormone synthesis
113908984 (ADCY4)
04928 Parathyroid hormone synthesis, secretion and action
113908984 (ADCY4)
04916 Melanogenesis
113908984 (ADCY4)
04925 Aldosterone synthesis and secretion
113908984 (ADCY4)
04927 Cortisol synthesis and secretion
113908984 (ADCY4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
113908984 (ADCY4)
04270 Vascular smooth muscle contraction
113908984 (ADCY4)
09154 Digestive system
04970 Salivary secretion
113908984 (ADCY4)
04971 Gastric acid secretion
113908984 (ADCY4)
04972 Pancreatic secretion
113908984 (ADCY4)
04976 Bile secretion
113908984 (ADCY4)
09156 Nervous system
04724 Glutamatergic synapse
113908984 (ADCY4)
04727 GABAergic synapse
113908984 (ADCY4)
04725 Cholinergic synapse
113908984 (ADCY4)
04723 Retrograde endocannabinoid signaling
113908984 (ADCY4)
09157 Sensory system
04742 Taste transduction
113908984 (ADCY4)
04750 Inflammatory mediator regulation of TRP channels
113908984 (ADCY4)
09149 Aging
04211 Longevity regulating pathway
113908984 (ADCY4)
04213 Longevity regulating pathway - multiple species
113908984 (ADCY4)
09159 Environmental adaptation
04713 Circadian entrainment
113908984 (ADCY4)
04714 Thermogenesis
113908984 (ADCY4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113908984 (ADCY4)
05207 Chemical carcinogenesis - receptor activation
113908984 (ADCY4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
113908984 (ADCY4)
05163 Human cytomegalovirus infection
113908984 (ADCY4)
09165 Substance dependence
05032 Morphine addiction
113908984 (ADCY4)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
113908984 (ADCY4)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
113908984 (ADCY4)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
113908984 (ADCY4)
Enzymes [BR:
zca01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
113908984 (ADCY4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
CD52
DUF4231
Motif
Other DBs
NCBI-GeneID:
113908984
NCBI-ProteinID:
XP_027425610
UniProt:
A0A6J2B0Y0
LinkDB
All DBs
Position
6:70969476..70985556
Genome browser
AA seq
1082 aa
AA seq
DB search
MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCALLAMLAVAYGSGRDLASDRG
FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSVLVWAALLGLGHGFQFTGGLVSAWDQV
SFFLFIIFTVYAMLPLGMWDAAAAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL
FLCGNVAGAYHKALMERALRATFREALRSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG
AYAVEDASMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR
YLESWGAAKPFAHLSHLESPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDEDLDTGDAK
FFQVIEQLNSQKQWKQSKDFNPLTLYFREKELEKEYRLSALPAFKYYAACTFLVFLSNFI
IQMLVTNRTPALAIAYSVTFLLFFLLLFVCFSEHLTKCVLKGPKMLHWLPTLSSLVATRP
GLRVALGTATILLVFVMAVTSLFFLPAASDCPSRAANVSSVASNLSWELPGSLPLISVPY
SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLGTSCSLFLHSHAWLSDCVLARLYPAPSDS
RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWQKKLRQEQEETETMENLTRL
LLENVLPAHVAPQFIGQNRRNEPPTLQDLYHQSYECVCVLFASVPDFKEFYSESNINHEG
LECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDTQQDAERSCSH
LGTMVEFAVALGSKLDVINKHSFNDFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVAS
RMESTGVLGKIQVTEETARVLQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRTGPPSAT
LG
NT seq
3249 nt
NT seq
+upstream
nt +downstream
nt
atggcccgcctcttcagtccccggccgccccccagcgaagacctcttctacgagacctac
tacagcctgagccagcagtacccactgctgcttctgctgctggtgatcgtgctctgcgcg
ctcctggcgatgctggctgtcgcctacggcagcggcagggatctagcttcagaccggggc
ttcctgaccactgtgctgtgcgcactgggtggcttctcgctgctcctgggcctggcttcc
cgcgagcaacgactgcagcgctggacacgccccctgtcggttctggtgtgggccgcgcta
ctcgggctaggccacggcttccagttcactgggggcctggtgagcgcctgggaccaggtg
tcctttttcctcttcatcatcttcaccgtgtatgccatgttgcccttgggcatgtgggat
gccgctgccgcaggccttgcctcatcactctcccacctgctggtccttgggctgtacctg
gggcctcagccggactcccggccggcgctgctgccgcagctggcagcaaacgccgtgtta
ttcctgtgtgggaacgtggccggggcgtaccacaaggcgctgatggagcgcgcgctgcgc
gccacgttccgggaggctcttcgttccctgcactcgcgccgccggctggacaccgagaag
aagcaccaggaacaccttctcttgtctatccttcctgcctacttggcccgagagatgaag
gcagagatcatggcacggctgcaggctggacaggggtcacggccagagagcaccaacaac
ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctatatgctgacatcgtg
ggcttcacgcggctggccagtgagtgctcccctaaggagttggtgctcatgctcaacgag
ctctttggcaagttcgaccagattgccaaggagcatgaatgcatgcggatcaagatcctg
ggcgactgttactactgtgtctctgggcttccgctctccctgccagaccacgccatcaac
tgcgtgcgcatggggctggacatgtgccgggccatcaggaaactccgggcagccactggc
gtagacatcaacatgcgtgtgggtgtgcattcgggcagtgtgctctgcggagtcatcggc
ctacagaagtggcagtatgatgtctggtcccatgatgtcacgctggccaaccacatggag
gcgggcggcgtgccaggacgagtacatattacaggggctaccctggccctgctggcaggg
gcttatgctgtggaggatgcatccatggaacaccgggacccataccttcgggagctaggg
gagcccacctacctagtcatcgatccccgggctgaggaggaggatgagaagggcactgcg
ggagggctgctgtcctctctcgagggtcccaagatgcggccgtcactgctgatgacccgc
tacctggagtcctggggcgcagccaagccttttgcccacctgagccacctagagagccct
gtgtccacctccacccctctcccggagaaggccctggcctccttcagcccccagtggagc
ctggaccggagccgtaccccccggggactggatgaggacctggacactggggacgccaag
ttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcagtcaaaggacttc
aacccattgacactgtacttcagagagaaggagctggagaaagagtatcgactctctgcc
ctccctgccttcaaatactatgcagcctgcaccttcctggtcttcctctccaatttcatc
atccagatgctggtgaccaacaggaccccagctctggccatcgcctatagtgtcaccttc
ctcctcttctttctccttctcttcgtctgcttctcagagcacctgacgaagtgtgtcttg
aaaggccccaagatgctgcactggctgcccaccctgtctagcctggtggccacgcggccc
ggcctgcgagttgccctgggcacggccaccatcctcctcgtttttgtcatggctgttacc
agcctgttcttcttaccggcagcatcagactgcccttcccgggctgccaatgtgtcctcc
gtggcttccaacctctcctgggagctccctgggtccctgcctctcatcagcgtcccatac
tctatgcactgctgcgtgctggggttcctgtcctgctccctctttctgcacatgagcttc
gagctgaagttactgttgctcctgctatggctggggacctcctgctccctcttcctgcac
tcccatgcctggctgtccgactgcgtcctcgcccgcctctatccggctccctcggactcc
aggccaggggtgctgaaggagcccaaactgatgggagctatctccttcttcatcttcttc
ttcaccctccttgtcctggctcggcagaatgagtattactgccgcctggacttcctgtgg
cagaagaagctgcggcaggagcaggaggagacagagacaatggagaacctgacacggcta
ctgctggagaatgtgctccctgcgcacgtggccccccagttcattggccagaaccggcgc
aacgagcctcccaccctccaggacctctaccaccagtcctacgagtgtgtctgtgtcctc
ttcgcctcagttccagactttaaggagttttactctgaatccaacatcaaccacgagggt
ctagagtgtctgcggctgctcaatgagatcattgctgattttgacgagctgctctcaaag
cccaagtttagtggggtggagaagatcaaaaccatcggcagcacctacatggcagccaca
ggcttaaatgccacctccggacaggacacacagcaggatgctgagcgaagctgcagccac
ctgggcaccatggtggagtttgcagtggcccttggatcgaagctggatgtcatcaataag
cactccttcaacgacttccgcctgcgtgtggggttgaaccatggacctgtagtagccgga
gtgattggggcccagaagcctcagtacgacatctggggcaacacggtgaacgtggccagc
cgcatggagagtactggagtcctgggcaaaatccaagtgactgaagagacagcccgggtg
ctgcagtccttaggctatacctgctacagccggggcatcatcaaggtcaaaggcaaaggg
cagctctgcacctacttcctgaacacagatttgacacgaactggcccgccttcggccacc
ctaggctga
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