Zalophus californianus (California sea lion): 113911010
Help
Entry
113911010 CDS
T07874
Symbol
EGFR
Name
(RefSeq) epidermal growth factor receptor isoform X1
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca01521
EGFR tyrosine kinase inhibitor resistance
zca01522
Endocrine resistance
zca04010
MAPK signaling pathway
zca04012
ErbB signaling pathway
zca04014
Ras signaling pathway
zca04015
Rap1 signaling pathway
zca04020
Calcium signaling pathway
zca04066
HIF-1 signaling pathway
zca04068
FoxO signaling pathway
zca04072
Phospholipase D signaling pathway
zca04144
Endocytosis
zca04151
PI3K-Akt signaling pathway
zca04510
Focal adhesion
zca04520
Adherens junction
zca04540
Gap junction
zca04630
JAK-STAT signaling pathway
zca04810
Regulation of actin cytoskeleton
zca04912
GnRH signaling pathway
zca04915
Estrogen signaling pathway
zca04921
Oxytocin signaling pathway
zca04926
Relaxin signaling pathway
zca04928
Parathyroid hormone synthesis, secretion and action
zca04934
Cushing syndrome
zca05160
Hepatitis C
zca05163
Human cytomegalovirus infection
zca05165
Human papillomavirus infection
zca05171
Coronavirus disease - COVID-19
zca05200
Pathways in cancer
zca05205
Proteoglycans in cancer
zca05206
MicroRNAs in cancer
zca05207
Chemical carcinogenesis - receptor activation
zca05208
Chemical carcinogenesis - reactive oxygen species
zca05210
Colorectal cancer
zca05212
Pancreatic cancer
zca05213
Endometrial cancer
zca05214
Glioma
zca05215
Prostate cancer
zca05218
Melanoma
zca05219
Bladder cancer
zca05223
Non-small cell lung cancer
zca05224
Breast cancer
zca05225
Hepatocellular carcinoma
zca05226
Gastric cancer
zca05230
Central carbon metabolism in cancer
zca05231
Choline metabolism in cancer
zca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113911010 (EGFR)
04012 ErbB signaling pathway
113911010 (EGFR)
04014 Ras signaling pathway
113911010 (EGFR)
04015 Rap1 signaling pathway
113911010 (EGFR)
04630 JAK-STAT signaling pathway
113911010 (EGFR)
04066 HIF-1 signaling pathway
113911010 (EGFR)
04068 FoxO signaling pathway
113911010 (EGFR)
04020 Calcium signaling pathway
113911010 (EGFR)
04072 Phospholipase D signaling pathway
113911010 (EGFR)
04151 PI3K-Akt signaling pathway
113911010 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
113911010 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
113911010 (EGFR)
04520 Adherens junction
113911010 (EGFR)
04540 Gap junction
113911010 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
113911010 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
113911010 (EGFR)
04915 Estrogen signaling pathway
113911010 (EGFR)
04921 Oxytocin signaling pathway
113911010 (EGFR)
04926 Relaxin signaling pathway
113911010 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
113911010 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113911010 (EGFR)
05206 MicroRNAs in cancer
113911010 (EGFR)
05205 Proteoglycans in cancer
113911010 (EGFR)
05207 Chemical carcinogenesis - receptor activation
113911010 (EGFR)
05208 Chemical carcinogenesis - reactive oxygen species
113911010 (EGFR)
05230 Central carbon metabolism in cancer
113911010 (EGFR)
05231 Choline metabolism in cancer
113911010 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113911010 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
113911010 (EGFR)
05212 Pancreatic cancer
113911010 (EGFR)
05225 Hepatocellular carcinoma
113911010 (EGFR)
05226 Gastric cancer
113911010 (EGFR)
05214 Glioma
113911010 (EGFR)
05218 Melanoma
113911010 (EGFR)
05219 Bladder cancer
113911010 (EGFR)
05215 Prostate cancer
113911010 (EGFR)
05213 Endometrial cancer
113911010 (EGFR)
05224 Breast cancer
113911010 (EGFR)
05223 Non-small cell lung cancer
113911010 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
113911010 (EGFR)
05171 Coronavirus disease - COVID-19
113911010 (EGFR)
05163 Human cytomegalovirus infection
113911010 (EGFR)
05165 Human papillomavirus infection
113911010 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
113911010 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113911010 (EGFR)
01522 Endocrine resistance
113911010 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113911010 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
zca04147
]
113911010 (EGFR)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
113911010 (EGFR)
Protein kinases [BR:
zca01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
113911010 (EGFR)
Exosome [BR:
zca04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
113911010 (EGFR)
Exosomal proteins of pancreatic cancer cells
113911010 (EGFR)
Exosomal proteins of bladder cancer cells
113911010 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
ABC1
Kdo
Borrelia_P83
Motif
Other DBs
NCBI-GeneID:
113911010
NCBI-ProteinID:
XP_027428940
EnsemblRapid:
ENSZCAG00025019216
UniProt:
A0A6J2BAA0
LinkDB
All DBs
Position
12:9080852..9278289
Genome browser
AA seq
1207 aa
AA seq
DB search
MRPSGTVGAALLVLLAAHFQASPALEEKKVCQGTSNRLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYMQRNYDLSFLKTIQEVAGYVLIALNTVQRIPLENLQIIRGNVLYENTHALS
VLSNYGTNKTGLQELPLRNLHEILQGAVRFSNNPVLCNVETIQWRDIVDSDFVSNMSMDF
QNQAGSCQKCDPDCPDGSCWGPGKENCQKLTKIICAQQCSGRCRGRSPSDCCHNQCAAGC
TGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYV
VTDHGSCVRACSSDNYEVEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIKHFK
NCTSISGDLHILPVAFRGDSFTRTLPLDPKELDILKTVKEITGFLLIQAWPENRTDLHAF
ENLEIIRGRTKQHGQFSLAVVGLDITSLGLRSLKEISDGDVIISGNQKLCYANTINWKKL
FGTSSQKTKIINNKDEKGCKAIGHVCHPLCSSEGCWGPEPKDCVSCRNVSRGRECVEKCN
VLEGEPREFVDNSECIQCHPECLPQAMNITCTGRGPDSCVKCAHYIDGPHCVKTCPAGVM
GENNTLVWKFADANRVCHLCHSNCTYGCAGPGLEGCATNGPKIPSIATGIVGGLLLVVVV
ALGVGLFLRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISTILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQ
QGFFHSPSTSRTPLLSSLSATSNNSTVACIDRNGSCPLKEDSFLQRYSSDPTGTLTEDNI
DDTFLPAPEYINQSVPKRPAGSVQNPVYHNQPLNPAPGRDPHYQNPHSNAVDNPEYLNTH
PPCVNSVLDGPSLWAQKGNHQISLDNPDYQQDFFPNEAKSNGIFKGPAAENADYLRVAPP
SSEFIGA
NT seq
3624 nt
NT seq
+upstream
nt +downstream
nt
atgcgaccctccggaacggtgggagccgcgctcctggtactgctggctgcgcacttccag
gcgagtccggcgctggaggaaaagaaagtttgccaaggcacaagtaaccgactcacccag
ttgggcacttttgaagaccactttctcagccttcagaggatgttcaataactgtgaggtg
gtccttgggaatttggaaattacctacatgcaaaggaattatgacctttccttcttaaag
accatccaggaagttgctggctacgtactcattgccctcaacacggtacagaggatccct
ttggaaaacctgcagatcatccgaggaaatgtgctctatgaaaacacccatgccttatcc
gtcttatccaattacggcacaaataagaccggattgcaggagcttcccctgagaaatcta
cacgaaatcctacaaggagctgtgcggttcagcaacaaccctgtcctctgcaacgtggaa
accatccagtggcgggatatcgttgacagcgattttgtaagcaatatgtcgatggacttc
cagaaccaagcgggcagttgccaaaagtgtgatccagactgtcccgatggaagttgttgg
ggtccgggaaaggagaattgccagaaattgaccaaaatcatctgtgcccagcagtgttca
gggcgctgccgtggcaggtcccccagtgactgctgtcacaaccagtgtgccgccggctgc
acggggccccgcgagagcgactgcctggtctgccgcaagttccgggatgaagccacatgc
aaggacacctgcccgccactcatgctctacaaccccaccacctaccagatggatgtcaac
ccagaaggaaagtacagctttggtgccacttgcgtgaagaaatgcccccgtaactacgtg
gtgacagaccacggttcgtgcgtccgtgcctgcagttccgacaactacgaggtagaggaa
gacggtgtccgcaaatgtaaaaagtgtgaggggccttgccgaaaagtgtgtaacggaata
ggaattggtgaatttaaagacacactttccataaatgctacaaacattaaacacttcaaa
aattgcacctcaatcagtggagatcttcatatcctgcccgtagcatttagaggtgactcc
ttcacgcgtactctacctctcgatccaaaggaactggatattctaaaaactgtaaaggaa
ataacagggtttctgctgattcaggcctggcccgaaaaccggaccgacctccatgctttt
gagaacctagaaatcatacgtggaagaacaaagcaacatggtcagttttctcttgcggtc
gtcggcctggacataacgtccttgggattacgctccctcaaggagataagtgacggagat
gtgatcatctcaggaaaccaaaaactgtgctatgcaaatacaataaactggaaaaaacta
tttgggacttcaagtcagaagaccaaaattataaacaacaaagatgaaaaaggctgcaag
gccatcggccacgtctgccatcccttatgctcatcagagggctgctggggcccagagccc
aaagactgtgtgtcctgccgaaacgtcagccggggcagggaatgtgtggagaagtgcaat
gttctggagggggagccaagggagtttgtggacaattccgagtgcatacagtgccatcca
gaatgcctgccccaggccatgaatataacctgcacaggacggggcccagacagctgtgtc
aagtgtgcccactacatcgacggccctcactgcgtcaagacgtgcccagctggtgtcatg
ggagagaacaataccctggtctggaagtttgccgatgccaaccgtgtgtgccacctgtgc
cattccaactgtacctacggttgtgctgggccaggtcttgaaggctgtgcgacaaacggg
cccaagatcccatccattgccaccggcattgtgggtggcctcctcttggtggtggtggtg
gcccttggggtgggcctctttttgcgccggcgccacatcgtccggaagcgcacgcttcgt
agactgctgcaagaaagagagcttgttgagcctcttacacccagcggagaagctcccaac
caagctctcttgaggatcttaaaggaaacagaattcaaaaagatcaaggtgctgggctct
ggagcgttcggcacggtgtacaagggactctggatcccggaaggtgagaaggttaaaatt
cccgtggccatcaaggaattaagagaagccacatctccaaaagccaacaaggaaattctt
gatgaagcctacgtgatggccagcgtagacaatcctcatgtgtgccgcctcctgggcatc
tgcctgacctccacggtccagcttatcacacagctcatgcccttcggctgcctcctggac
tatgtgcgcgagcacaaggacaacattggctcccagtacctgctcaactggtgtgtgcag
attgcaaagggcatgaactacctggaagaccggcgcttggtgcaccgcgacctggcagcc
agaaatgtcctggtgaagacaccacagcatgtcaagatcacagattttgggctggccaaa
ctgcttggagccgaggagaaagagtaccacgcagaaggaggcaaagtgcctatcaagtgg
atggctttggaatcaattttacaccgaatttatacccaccaaagtgatgtgtggagctat
ggagtcaccgtttgggagttgatgacctttgggtccaagccttatgacggtatccccgca
agtgagatctcaaccatcctggagaaaggagagcgcctcccacagccgcccatatgcacc
atcgatgtctacatgatcatggtcaagtgctggatgatagatgcagacagtcgccccaaa
ttccgtgaattgatcatcgaattctccaaaatggcccgagacccccagcgctacctcgtc
atccagggagacgagaggatgcatttgccaagccctacagactccaacttttaccgtgcc
ctgatggacgaagaggacatggaagacgttgtcgatgccgatgagtacctcatcccccag
cagggcttcttccatagcccctccacatcccggacgcccctcctgagttctctgagtgcc
accagcaacaattccaccgtggcttgcattgacagaaatgggagctgccccctcaaagaa
gacagcttccttcaacggtacagctcagaccccactggcaccttgaccgaggacaacata
gatgacactttcctcccagcacctgaatacataaaccaatccgttcccaaaagacctgcg
ggttctgtccagaaccccgtctatcacaatcagcctctaaatccagctcctggcagagac
cctcactaccaaaatccccacagcaacgcagtggacaaccctgagtatctcaacacccat
cctccctgcgtcaacagtgtgctcgacggccccagcctctgggcccagaaaggcaaccac
caaatcagcctggacaaccctgactaccagcaggacttctttcccaacgaagccaagtca
aatggcatttttaagggccctgcagctgaaaatgcagactacctgagggtagcaccacca
agcagtgagtttatcggagcatga
DBGET
integrated database retrieval system
