Zalophus californianus (California sea lion): 113911462
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Entry
113911462 CDS
T07874
Symbol
GCK
Name
(RefSeq) hexokinase-4 isoform X1
KO
K12407
glucokinase [EC:
2.7.1.2
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca00010
Glycolysis / Gluconeogenesis
zca00052
Galactose metabolism
zca00500
Starch and sucrose metabolism
zca00520
Amino sugar and nucleotide sugar metabolism
zca00524
Neomycin, kanamycin and gentamicin biosynthesis
zca01100
Metabolic pathways
zca01200
Carbon metabolism
zca01250
Biosynthesis of nucleotide sugars
zca04910
Insulin signaling pathway
zca04911
Insulin secretion
zca04917
Prolactin signaling pathway
zca04922
Glucagon signaling pathway
zca04930
Type II diabetes mellitus
zca04950
Maturity onset diabetes of the young
zca05230
Central carbon metabolism in cancer
Module
zca_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
zca_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
113911462 (GCK)
00052 Galactose metabolism
113911462 (GCK)
00500 Starch and sucrose metabolism
113911462 (GCK)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
113911462 (GCK)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
113911462 (GCK)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
113911462 (GCK)
04910 Insulin signaling pathway
113911462 (GCK)
04922 Glucagon signaling pathway
113911462 (GCK)
04917 Prolactin signaling pathway
113911462 (GCK)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
113911462 (GCK)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
113911462 (GCK)
04950 Maturity onset diabetes of the young
113911462 (GCK)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.2 glucokinase
113911462 (GCK)
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GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Motif
Other DBs
NCBI-GeneID:
113911462
NCBI-ProteinID:
XP_027429935
UniProt:
A0A6J2BD50
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Position
12:complement(200551..236906)
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AA seq
466 aa
AA seq
DB search
MTMGATRSQAQTASNLAEQILADFQLQEADLKKVMRRMQKEMARGLRLETHEEASVKMLP
TYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVTTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQ
NVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMG
ELVRLVLLKLVDENLLFRGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRP
SATDCDIVRRACESVSTRAAHMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSF
KERFHASVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atgacgatgggtgccaccaggagccaggcccagacagcctcgaatctggcagagcagatc
ctggccgacttccagctgcaggaggctgacttgaagaaggtgatgcggcggatgcagaag
gagatggcgcggggcctgcggctggagacccacgaggaggccagcgtgaagatgctgccc
acctacgtgcgctccaccccagagggctcagaagtcggggacttcctctccctggacctg
ggcggcaccaacttcagggtgatgctggtgaaggtgggggagggcgaggaggggcagtgg
agtgtgacaaccaaacaccagatgtactccatccccgaggatgccatgaccggcactgct
gagatgctctttgactacatctccgagtgcatctctgacttcctggacaagcatcagatg
aagcacaagaaactgcccttgggcttcaccttctccttccccgtgaggcatgaagacatc
gacaagggcatcctcctcaattggaccaagggcttcaaggcctctggagcagaagggaac
aacatcgtggggctcctccgcgacgccatcaaacggagaggggactttgaaatggacgtg
gtagcaatggtgaacgacacagtggccacaatgatctcctgctactatgaagaccgccgg
tgtgaggttggcatgattgtgggcacaggctgtaatgcttgctacatggaggagatgcag
aacgtggagctcgtggaaggggacgagggccgcatgtgcgtcaacactgagtggggcgcc
tttggggactccggtgagctggacgagttcctgctggagtacgaccgcgtggtggacgag
aactccctgaaccccggccagcagctgtacgagaagctcatcggcggcaagtacatgggc
gagctggtgcggctcgtgctgctaaaactcgtggacgaaaacctgcttttccgcggggag
gcgtcggaacagctgcgcacgcgcggcgccttcgagacgcgcttcgtgtcgcaggtggag
agcgactcaggcgaccgcaagcagatctacaacatcctgagcacgctggggctgaggccc
tcggccaccgactgcgacatcgtgcgccgcgcctgcgagagcgtgtccacgcgcgccgcg
cacatgtgcgccgcggggctggcgggcgtcattaaccgcatgcgcgagagccgcagcgag
gacgtgatgcgcatcaccgtgggcgtggacggctccgtgtacaagctgcaccccagcttc
aaggagaggttccacgccagcgtgcgcaggctgacgcccagctgcgagatcaccttcatc
gagtcggaggagggcagtggccggggtgcggccctgatctcggcggtggcctgcaagaag
gcctgcatgctgggccagtga
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